Effects of Pioglitazone on Nonalcoholic Fatty Liver Disease in the Absence of Constitutive Androstane Receptor Expression von Cho, Bo Youn, Park, Changhun, Hwang, Ji-Yeon, Kim, Hwan Hee, Ahn, Hwa Young, Park, Young Joo

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Ligand and Target Discovery by Fragment-Based Screening in Human Cells von Parker, Christopher G., Galmozzi, Andrea, Wang, Yujia, Correia, Bruno E., Sasaki, Kenji, Joslyn, Christopher M., Kim, Arthur S., Cavallaro, Cullen L., Lawrence, R. Michael, Johnson, Stephen R., Narvaiza, Iñigo, Saez, Enrique, Cravatt, Benjamin F.

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Pharmacologic IRE1/XBP1s activation promotes systemic adaptive remodeling in obesity von Madhavan, Aparajita, Kok, Bernard P., Rius, Bibiana, Grandjean, Julia M. D., Alabi, Adekunle, Albert, Verena, Sukiasyan, Ara, Powers, Evan T., Galmozzi, Andrea, Saez, Enrique, Wiseman, R. Luke

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Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue von GALMOZZI, Andrea, MITRO, Nico, VALENTE, Sergio, GUERRINI, Uliano, CARUSO, Donatella, MAI, Antonello, SAEZ, Enrique, DE FABIANI, Emma, CRESTANI, Maurizio, FERRARI, Alessandra, GERS, Elise, GILARDI, Federica, GODIO, Cristina, CERMENATI, Gaia, GUALERZI, Alice, DONETTI, Elena, ROTILI, Dante

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T0901317 is a potent PXR ligand: Implications for the biology ascribed to LXR von Mitro, Nico, Vargas, Leo, Romeo, Russell, Koder, Alan, Saez, Enrique

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Structure and Mobility of Dissociated Vacancies at Twist Grain Boundaries and Screw Dislocations in Ionic Rocksalt Compounds von Kolluri, Kedarnath, Martinez Saez, Enrique, Uberuaga, Blas Pedro

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Isolation and Differentiation of Primary White and Brown Preadipocytes from Newborn Mice von Galmozzi, Andrea, Kok, Bernard P., Saez, Enrique

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Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension von Rinschen, Markus M., Palygin, Oleg, El-Meanawy, Ashraf, Domingo-Almenara, Xavier, Palermo, Amelia, Dissanayake, Lashodya V., Golosova, Daria, Schafroth, Michael A., Guijas, Carlos, Demir, Fatih, Jaegers, Johannes, Gliozzi, Megan L., Xue, Jingchuan, Hoehne, Martin, Benzing, Thomas, Kok, Bernard P., Saez, Enrique, Bleich, Markus, Himmerkus, Nina, Weisz, Ora A., Cravatt, Benjamin F., Krüger, Marcus, Benton, H. Paul, Siuzdak, Gary, Staruschenko, Alexander

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Intestinal bitter taste receptor activation alters hormone secretion and imparts metabolic benefits von Kok, Bernard P., Galmozzi, Andrea, Littlejohn, Nicole K., Albert, Verena, Godio, Cristina, Kim, Woojoo, Kim, Sean M., Bland, Jeffrey S., Grayson, Neile, Fang, Mingliang, Meyerhof, Wolfgang, Siuzdak, Gary, Srinivasan, Supriya, Behrens, Maik, Saez, Enrique

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Activation of Kappa Opioid Receptor Regulates the Hypothermic Response to Calorie Restriction and Limits Body Weight Loss von Cintron-Colon, Rigo, Johnson, Christopher W., Montenegro-Burke, J. Rafael, Guijas, Carlos, Faulhaber, Lila, Sanchez-Alavez, Manuel, Aguirre, Carlos A., Shankar, Kokila, Singh, Mona, Galmozzi, Andrea, Siuzdak, Gary, Saez, Enrique, Conti, Bruno

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Chemical short-range order in derivative Cr-Ta-Ti-V-W high entropy alloys from the first-principles thermodynamic study von Sobieraj, Damian, Wróbel, Jan S, Rygier, Tomasz, Kurzyd owski, Krzysztof J, El Atwani, Osman, Devaraj, Arun, Martinez Saez, Enrique, Nguyen-Manh, Duc

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Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes von Dominguez, Eduardo, Galmozzi, Andrea, Chang, Jae Won, Hsu, Ku-Lung, Pawlak, Joanna, Li, Weiwei, Godio, Cristina, Thomas, Jason, Partida, David, Niessen, Sherry, O'Brien, Paul E, Russell, Aaron P, Watt, Matthew J, Nomura, Daniel K, Cravatt, Benjamin F, Saez, Enrique

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Discovery of small-molecule enzyme activators by activity-based protein profiling von Kok, Bernard P., Ghimire, Srijana, Kim, Woojoo, Chatterjee, Shreyosree, Johns, Tyler, Kitamura, Seiya, Eberhardt, Jerome, Ogasawara, Daisuke, Xu, Janice, Sukiasyan, Ara, Kim, Sean M., Godio, Cristina, Bittencourt, Julia M., Cameron, Michael, Galmozzi, Andrea, Forli, Stefano, Wolan, Dennis W., Cravatt, Benjamin F., Boger, Dale L., Saez, Enrique

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TLE3 Is a Dual-Function Transcriptional Coregulator of Adipogenesis von Villanueva, Claudio J., Waki, Hironori, Godio, Cristina, Nielsen, Ronni, Chou, Wen-Ling, Vargas, Leo, Wroblewski, Kevin, Schmedt, Christian, Chao, Lily C., Boyadjian, Rima, Mandrup, Susanne, Hevener, Andrea, Saez, Enrique, Tontonoz, Peter

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Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function von Wortham, Matthew, Benthuysen, Jacqueline R., Wallace, Martina, Savas, Jeffrey N., Mulas, Francesca, Divakaruni, Ajit S., Liu, Fenfen, Albert, Verena, Taylor, Brandon L., Sui, Yinghui, Saez, Enrique, Murphy, Anne N., Yates, John R., Metallo, Christian M., Sander, Maike

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Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation von Cermenati, Gaia, Abbiati, Federico, Cermenati, Solei, Brioschi, Elisabetta, Volonterio, Alessandro, Cavaletti, Guido, Saez, Enrique, De Fabiani, Emma, Crestani, Maurizio, Garcia-Segura, Luis M., Melcangi, Roberto C., Caruso, Donatella, Mitro, Nico

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ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue von Galmozzi, Andrea, Sonne, Si B, Altshuler-Keylin, Svetlana, Hasegawa, Yutaka, Shinoda, Kosaku, Luijten, Ineke H N, Chang, Jae Won, Sharp, Louis Z, Cravatt, Benjamin F, Saez, Enrique, Kajimura, Shingo

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RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs von Wang, Jiexin, Rajbhandari, Prashant, Damianov, Andrey, Han, Areum, Sallam, Tamer, Waki, Hironori, Villanueva, Claudio J, Lee, Stephen D, Nielsen, Ronni, Mandrup, Susanne, Reue, Karen, Young, Stephen G, Whitelegge, Julian, Saez, Enrique, Black, Douglas L, Tontonoz, Peter

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Activation of the liver X receptor increases neuroactive steroid levels and protects from diabetes-induced peripheral neuropathy von Cermenati, Gaia, Giatti, Silvia, Cavaletti, Guido, Bianchi, Roberto, Maschi, Omar, Pesaresi, Marzia, Abbiati, Federico, Volonterio, Alessandro, Saez, Enrique, Caruso, Donatella, Melcangi, Roberto Cosimo, Mitro, Nico

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Activation of Liver X Receptor Improves Glucose Tolerance through Coordinate Regulation of Glucose Metabolism in Liver and Adipose Tissue von Laffitte, Bryan A., Chao, Lily C., Li, Jing, Walczak, Robert, Hummasti, Sarah, Joseph, Sean B., Castrillo, Antonio, Wilpitz, Damien C., Mangelsdorf, David J., Collins, Jon L., Saez, Enrique, Tontonoz, Peter

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