The ability of molecular docking to unravel the controversy and challenges related to P-glycoprotein—a well-known, yet poorly understood drug transporter von Zeino, Maen, Saeed, Mohamed E. M., Kadioglu, Onat, Efferth, Thomas

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Collateral sensitivity of natural products in drug-resistant cancer cells von Efferth, Thomas, Saeed, Mohamed E.M., Kadioglu, Onat, Seo, Ean-Jeong, Shirooie, Samira, Mbaveng, Armelle T., Nabavi, Seyed Mohammad, Kuete, Victor

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Chemopreventive Property of Sencha Tea Extracts towards Sensitive and Multidrug-Resistant Leukemia and Multiple Myeloma Cells von Lu, Xiaohua, Saeed, Mohamed E M, Hegazy, Mohamed-Elamir F, Kampf, Christopher J, Efferth, Thomas

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Anti-inflammatory and tight junction protective activity of the herbal preparation STW 5-II on mouse intestinal organoids von Elbadawi, Mohamed, Ammar, Ramy M., Aziz-Kalbhenn, Heba, Rabini, Sabine, Klauck, Sabine M., Dawood, Mona, Saeed, Mohamed E M, Kampf, Christopher J., Efferth, Thomas

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Identification of novel drug resistance mechanisms by genomic and transcriptomic profiling of glioblastoma cells with mutation-activated EGFR von Kadioglu, Onat, Saeed, Mohamed E.M., Mahmoud, Nuha, Azawi, Shaymaa, Mrasek, Kristin, Liehr, Thomas, Efferth, Thomas

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Targeting epidermal growth factor receptors and downstream signaling pathways in cancer by phytochemicals von Kadioglu, Onat, Cao, Jingming, Saeed, Mohamed E. M., Greten, Henry Johannes, Efferth, Thomas

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In Silico and In Vitro Screening of 50 Curcumin Compounds as EGFR and NF-κB Inhibitors von Saeed, Mohamed E M, Yücer, Rümeysa, Dawood, Mona, Hegazy, Mohamed-Elamir F, Drif, Assia, Ooko, Edna, Kadioglu, Onat, Seo, Ean-Jeong, Kamounah, Fadhil S, Titinchi, Salam J, Bachmeier, Beatrice, Efferth, Thomas

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Synthesis of Thymoquinone–Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents von Fröhlich, Tony, Reiter, Christoph, Saeed, Mohamed E. M, Hutterer, Corina, Hahn, Friedrich, Leidenberger, Maria, Friedrich, Oliver, Kappes, Barbara, Marschall, Manfred, Efferth, Thomas, Tsogoeva, Svetlana B

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Prevention of carcinogenesis and metastasis by Artemisinin-type drugs von Abba, Mohammed L., Patil, Nitin, Leupold, Jörg Hendrik, Saeed, Mohamed E.M., Efferth, Thomas, Allgayer, Heike

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Xylochemical Synthesis and Biological Evaluation of Shancigusin C and Bletistrin G von Geske, Leander, Kauhl, Ulrich, Saeed, Mohamed E M, Schüffler, Anja, Thines, Eckhard, Efferth, Thomas, Opatz, Till

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Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR) von Saeed, Mohamed E M, Mahmoud, Nuha, Sugimoto, Yoshikazu, Efferth, Thomas, Abdel-Aziz, Heba

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Identification of metastasis-related genes by genomic and transcriptomic studies in murine melanoma von Kadioglu, Onat, Saeed, Mohamed E.M., Mahmoud, Nuha, Hussein Azawi, Shaymaa S., Rincic, Martina, Liehr, Thomas, Efferth, Thomas

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Molecular Determinants of Sensitivity or Resistance of Cancer Cells Toward Sanguinarine von Saeed, Mohamed E M, Mahmoud, Nuha, Sugimoto, Yoshikazu, Efferth, Thomas, Abdel-Aziz, Heba

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Repurposing of the ALK Inhibitor Crizotinib for Acute Leukemia and Multiple Myeloma Cells von Boulos, Joelle C., Saeed, Mohamed E. M., Chatterjee, Manik, Bülbül, Yagmur, Crudo, Francesco, Marko, Doris, Munder, Markus, Klauck, Sabine M., Efferth, Thomas

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Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma von Saeed, Mohamed E. M., Kadioglu, Onat, Greten, Henry Johannes, Yildirim, Adem, Mayr, Katharina, Wenz, Frederik, Giordano, Frank A., Efferth, Thomas

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Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells von Ooko, Edna, Saeed, Mohamed E.M., Kadioglu, Onat, Sarvi, Shabnam, Colak, Merve, Elmasaoudi, Kaoutar, Janah, Rabab, Greten, Henry J., Efferth, Thomas

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Modulation of P-glycoprotein activity by novel synthetic curcumin derivatives in sensitive and multidrug-resistant T-cell acute lymphoblastic leukemia cell lines von Ooko, Edna, Alsalim, Tahseen, Saeed, Bahjat, Saeed, Mohamed E.M., Kadioglu, Onat, Abbo, Hanna S., Titinchi, Salam J.J., Efferth, Thomas

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Protein Expression Profiling and Virtual Drug Screening as an Approach for Individualized Therapy of Small Cell Vaginal Carcinoma von SAEED, MOHAMED E.M., KHALID, HASSAN E., THAKUR, SAILESH K., EFFERTH, THOMAS

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Disruption of Lipid Raft Microdomains, Regulation of CD38, TP53, and MYC Signaling, and Induction of Apoptosis by Lomitapide in Multiple Myeloma Cells von SAEED, MOHAMED E. M., BOULOS, JOELLE C., MÜCKLICH, SABRINA B., LEICH, ELLEN, CHATTERJEE, MANIK, KLAUCK, SABINE M., EFFERTH, THOMAS

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Pharmacogenomic and molecular docking studies on the cytotoxicity of the natural steroid wortmannin against multidrug-resistant tumor cells von Kuete, Victor, Saeed, Mohamed E.M., Kadioglu, Onat, Börtzler, Jonas, Khalid, Hassan, Greten, Henry Johannes, Efferth, Thomas

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