Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach von Krug, Anne K., Kolde, Raivo, Gaspar, John A., Rempel, Eugen, Balmer, Nina V., Meganathan, Kesavan, Vojnits, Kinga, Baquié, Mathurin, Waldmann, Tanja, Ensenat-Waser, Roberto, Jagtap, Smita, Evans, Richard M., Julien, Stephanie, Peterson, Hedi, Zagoura, Dimitra, Kadereit, Suzanne, Gerhard, Daniel, Sotiriadou, Isaia, Heke, Michael, Natarajan, Karthick, Henry, Margit, Winkler, Johannes, Marchan, Rosemarie, Stoppini, Luc, Bosgra, Sieto, Westerhout, Joost, Verwei, Miriam, Vilo, Jaak, Kortenkamp, Andreas, Hescheler, Jürgen, Hothorn, Ludwig, Bremer, Susanne, van Thriel, Christoph, Krause, Karl-Heinz, Hengstler, Jan G., Rahnenführer, Jörg, Leist, Marcel, Sachinidis, Agapios

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Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP von Krug, A K, Gutbier, S, Zhao, L, Pöltl, D, Kullmann, C, Ivanova, V, Förster, S, Jagtap, S, Meiser, J, Leparc, G, Schildknecht, S, Adam, M, Hiller, K, Farhan, H, Brunner, T, Hartung, T, Sachinidis, A, Leist, M

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Differences in the Early Development of Human and Mouse Embryonic Stem Cells von Gabdoulline, R, Kaisers, W, Gaspar, A, Meganathan, K, Doss, M X, Jagtap, S, Hescheler, J, Sachinidis, A, Schwender, H

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Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells von Meganathan, K, Jagtap, S, Srinivasan, S P, Wagh, V, Hescheler, J, Hengstler, J, Leist, M, Sachinidis, A

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Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery von Zimmer, B., Pallocca, G., Dreser, N., Foerster, S., Waldmann, T., Westerhout, J., Julien, S., Krause, K. H., van Thriel, C., Hengstler, J. G., Sachinidis, A., Bosgra, S., Leist, M.

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Cytosine arabinoside induces ectoderm and inhibits mesoderm expression in human embryonic stem cells during multilineage differentiation von Jagtap, S, Meganathan, K, Gaspar, J, Wagh, V, Winkler, J, Hescheler, J, Sachinidis, A

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Fam40b is required for lineage commitment of murine embryonic stem cells von Wagh, V, Doss, M X, Sabour, D, Niemann, R, Meganathan, K, Jagtap, S, Gaspar, J A, Ardestani, M A, Papadopoulos, S, Gajewski, M, Winkler, J, Hescheler, J, Sachinidis, A

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A method for the rapid construction of cRNA standard curves in quantitative real-time reverse transcription polymerase chain reaction von Fronhoffs, S., Totzke, G., Stier, S., Wernert, N., Rothe, M., Brüning, T., Koch, B., Sachinidis, A., Vetter, H., Ko, Y.

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Genome-wide expression changes induced by bisphenol A, F and S in human stem cell derived hepatocyte-like cells von Lucendo-Villarin, B, Nell, P, Hellwig, B, Filis, P, Feuerborn, D, O'Shaughnessy, P J, Godoy, P, Rahnenführer, J, Hengstler, J G, Cherianidou, A, Sachinidis, A, Fowler, P A, Hay, D C

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Effective surface-based cryopreservation of human embryonic stem cells by vitrification von Beier, A.F.J., Schulz, J.C., Dörr, D., Katsen-Globa, A., Sachinidis, A., Hescheler, J., Zimmermann, H.

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Upregulation of vascular angiotensin II receptor gene expression by low-density lipoprotein in vascular smooth muscle cells von NICKENING, G, SACHINIDIS, A, MICHAELSEN, F, BÖHM, M, SEEWALD, S, VETTER, H

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Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells von Godoy, Patricio, Schmidt-Heck, Wolfgang, Natarajan, Karthick, Lucendo-Villarin, Baltasar, Szkolnicka, Dagmara, Asplund, Annika, Björquist, Petter, Widera, Agata, Stöber, Regina, Campos, Gisela, Hammad, Seddik, Sachinidis, Agapios, Chaudhari, Umesh, Damm, Georg, Weiss, Thomas S, Nüssler, Andreas, Synnergren, Jane, Edlund, Karolina, Küppers-Munther, Barbara, Hay, David C, Hengstler, Jan G

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Evaluation of Developmental Toxicants and Signaling Pathways in a Functional Test Based on the Migration of Human Neural Crest Cells von Zimmer, Bastian, Lee, Gabsang, Balmer, Nina V., Meganathan, Kesavan, Sachinidis, Agapios, Studer, Lorenz, Leist, Marcel

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Signaling molecules, transcription growth factors and other regulators revealed from in-vivo and in-vitro models for the regulation of cardiac development von Meganathan, Kesavan, Sotiriadou, Isaia, Natarajan, Karthick, Hescheler, Jürgen, Sachinidis, Agapios

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A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors von Rempel, Eugen, Hoelting, Lisa, Waldmann, Tanja, Balmer, Nina V., Schildknecht, Stefan, Grinberg, Marianna, Das Gaspar, John Antony, Shinde, Vaibhav, Stöber, Regina, Marchan, Rosemarie, van Thriel, Christoph, Liebing, Julia, Meisig, Johannes, Blüthgen, Nils, Sachinidis, Agapios, Rahnenführer, Jörg, Hengstler, Jan G., Leist, Marcel

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Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells von Waldmann, Tanja, Rempel, Eugen, Balmer, Nina V, König, André, Kolde, Raivo, Gaspar, John Antonydas, Henry, Margit, Hescheler, Jürgen, Sachinidis, Agapios, Rahnenführer, Jörg, Hengstler, Jan G, Leist, Marcel

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Limitations of the reverse transcription-polymerase chain reaction method for the detection of carcinoembryonic antigen-positive tumor cells in peripheral blood von YON KO, KLINZ, M, TOTZKE, G, GOUNI-BERTHOLD, I, SACHINIDIS, A, VETTER, H

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Derivation of es Cells From Early Stage Preimplantation Embryos and Characterisation of their Cardiac Differentiation Potential in Mice von Bag, S, Pfannkuche, K, Krzyzak, V, Wagner, B, Sachinidis, A, Hescheler, J

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Lineage-specific regulation of epigenetic modifier genes in human liver and brain von Weng, Matthias K, Natarajan, Karthick, Scholz, Diana, Ivanova, Violeta N, Sachinidis, Agapios, Hengstler, Jan G, Waldmann, Tanja, Leist, Marcel

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Regulation of Liver Metabolism by the Endosomal GTPase Rab5 von Zeigerer, Anja, Bogorad, Roman L., Sharma, Kirti, Gilleron, Jerome, Seifert, Sarah, Sales, Susanne, Berndt, Nikolaus, Bulik, Sascha, Marsico, Giovanni, D’Souza, Rochelle C.J., Lakshmanaperumal, Naharajan, Meganathan, Kesavan, Natarajan, Karthick, Sachinidis, Agapios, Dahl, Andreas, Holzhütter, Hermann-Georg, Shevchenko, Andrej, Mann, Matthias, Koteliansky, Victor, Zerial, Marino

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