Phosphorylation-driven aggregative proteins in neurodegenerative diseases: implications and therapeutics von Espargaró, Alba, Sabate, Raimon

Volltext

On the Binding of Congo Red to Amyloid Fibrils von Espargaró, Alba, Llabrés, Salomé, Saupe, Sven J., Curutchet, Carles, Luque, F. Javier, Sabaté, Raimon

Volltext

Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents von Viayna, Elisabet, Sola, Irene, Bartolini, Manuela, De Simone, Angela, Tapia-Rojas, Cheril, Serrano, Felipe G, Sabaté, Raimon, Juárez-Jiménez, Jordi, Pérez, Belén, Luque, F. Javier, Andrisano, Vincenza, Clos, M. Victòria, Inestrosa, Nibaldo C, Muñoz-Torrero, Diego

Volltext

New Pyrimidine and Pyridine Derivatives as Multitarget Cholinesterase Inhibitors: Design, Synthesis, and In Vitro and In Cellulo Evaluation von Bortolami, Martina, Pandolfi, Fabiana, Tudino, Valeria, Messore, Antonella, Madia, Valentina Noemi, De Vita, Daniela, Di Santo, Roberto, Costi, Roberta, Romeo, Isabella, Alcaro, Stefano, Colone, Marisa, Stringaro, Annarita, Espargaró, Alba, Sabatè, Raimon, Scipione, Luigi

Volltext

1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer’s disease von Wichur, Tomasz, Więckowska, Anna, Więckowski, Krzysztof, Godyń, Justyna, Jończyk, Jakub, Valdivieso, Álvaro del Río, Panek, Dawid, Pasieka, Anna, Sabaté, Raimon, Knez, Damijan, Gobec, Stanislav, Malawska, Barbara

Volltext

Copper, dityrosine cross-links and amyloid-β aggregation von Vázquez, Guillem, Caballero, Ana B., Kokinda, Jakub, Hijano, Ana, Sabaté, Raimon, Gamez, Patrick

Volltext

Novel drug-like fluorenyl derivatives as selective butyrylcholinesterase and β-amyloid inhibitors for the treatment of Alzheimer’s disease von Pasieka, Anna, Panek, Dawid, Zaręba, Paula, Sługocka, Emilia, Gucwa, Natalia, Espargaró, Alba, Latacz, Gniewomir, Khan, Nadia, Bucki, Adam, Sabaté, Raimon, Więckowska, Anna, Malawska, Barbara

Volltext

Thioflavin-T excimer formation upon interaction with amyloid fibers von Sabate, Raimon, Rodriguez-Santiago, Luis, Sodupe, Mariona, Saupe, Sven J, Ventura, Salvador

Volltext

Air Curtains Equipped With Hydroalcoholic Aerosol Sprayers for Massive COVID-19 Disinfection von Raventós, Judit, Sabate, Raimon

Volltext

A versatile luminescent probe for sensing and monitoring amyloid proteins von Vázquez, Guillem, Espargaró, Alba, Caballero, Ana B., Di Pede-Mattatelli, Ania, Busquets, M. Antònia, Nawrot, Daria, Sabaté, Raimon, Nicolás, Ernesto, Juárez-Jiménez, Jordi, Gamez, Patrick

Volltext

Design, Synthesis, and Biological Evaluation of 1‑Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer’s Agents von Panek, Dawid, Więckowska, Anna, Jończyk, Jakub, Godyń, Justyna, Bajda, Marek, Wichur, Tomasz, Pasieka, Anna, Knez, Damijan, Pišlar, Anja, Korabecny, Jan, Soukup, Ondrej, Sepsova, Vendula, Sabaté, Raimon, Kos, Janko, Gobec, Stanislav, Malawska, Barbara

Volltext

Potential applications of magnetic particles to detect and treat Alzheimer's disease von Busquets, Maria Antònia, Sabaté, Raimon, Estelrich, Joan

Volltext

Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease von Tonelli, Michele, Catto, Marco, Sabaté, Raimon, Francesconi, Valeria, Laurini, Erik, Pricl, Sabrina, Pisani, Leonardo, Miniero, Daniela Valeria, Liuzzi, Grazia Maria, Gatta, Elena, Relini, Annalisa, Gavín, Rosalina, Del Rio, Jose Antonio, Sparatore, Fabio, Carotti, Angelo

Volltext

Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease... von Zaręba, Paula, Łątka, Kamil, Mazur, Gabriela, Gryzło, Beata, Pasieka, Anna, Godyń, Justyna, Panek, Dawid, Skrzypczak-Wiercioch, Anna, Höfner, Georg C., Latacz, Gniewomir, Maj, Maciej, Espargaró, Alba, Sabaté, Raimon, Jóźwiak, Krzysztof, Wanner, Klaus T., Sałat, Kinga, Malawska, Barbara, Kulig, Katarzyna, Bajda, Marek

Volltext

Regioselective synthesis of 7-O-esters of the flavonolignan silibinin and SARs lead to compounds with overadditive neuroprotective effects von Schramm, Simon, Huang, Guozheng, Gunesch, Sandra, Lang, Florian, Roa, Judit, Högger, Petra, Sabaté, Raimon, Maher, Pamela, Decker, Michael

Volltext

Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies von Di Pietro, Ornella, Pérez-Areales, F. Javier, Juárez-Jiménez, Jordi, Espargaró, Alba, Clos, M. Victòria, Pérez, Belén, Lavilla, Rodolfo, Sabaté, Raimon, Luque, F. Javier, Muñoz-Torrero, Diego

Volltext

New cyclopentaquinoline and 3,5-dichlorobenzoic acid hybrids with neuroprotection against oxidative stress for the treatment of Alzheimer's disease von Czarnecka, Kamila, Girek, Małgorzata, Kręcisz, Paweł, Skibiński, Robert, Łątka, Kamil, Jończyk, Jakub, Bajda, Marek, Szymczyk, Piotr, Galita, Grzegorz, Kabziński, Jacek, Majsterek, Ireneusz, Espargaró, Alba, Sabate, Raimon, Szymański, Paweł

Volltext

Azobioisosteres of Curcumin with Pronounced Activity against Amyloid Aggregation, Intracellular Oxidative Stress, and Neuroinflammation von Hofmann, Julian, Ginex, Tiziana, Espargaró, Alba, Scheiner, Matthias, Gunesch, Sandra, Aragó, Marc, Stigloher, Christian, Sabaté, Raimon, Luque, F. Javier, Decker, Michael

Volltext

Natural Xanthones from Garcinia mangostana with Multifunctional Activities for the Therapy of Alzheimer’s Disease von Wang, Sheng-nan, Li, Qian, Jing, Ming-hua, Alba, Espargaró, Yang, Xiao-hong, Sabaté, Raimon, Han, Yi-fan, Pi, Rong-biao, Lan, Wen-jian, Yang, Xiao-bo, Chen, Jing-kao

Volltext

On the binding of Thioflavin-T to HET-s amyloid fibrils assembled at pH 2 von Sabaté, Raimon, Lascu, Ioan, Saupe, Sven J.

Volltext