A multihit, multistage model of chemical carcinogenesis von Owens, David M., Wei, S.-J. Caroline, Smart, Robert C.

Volltext

Studies on the Metabolism of Benzo[a]Pyrene and Dose-Dependent Differences in the Mutagenic Profile of Its Ultimate Carcinogenic Metabolite von Conney, Allan H., Chang, Richard L., Jerina, Donald M., Caroline Wei, S.-J.

Volltext

Characterization of hprt splicing mutations induced by the ultimate carcinogenic metabolite of benzo[a]pyrene in Chinese hamster V-79 cells von HENNIG, E. E, CONNEY, A. H, WEI, S.-J. C

Volltext

A Single Site-specific trans-Opened 7,8,9,10-Tetrahydrobenzo[a]pyrene 7,8-Diol 9,10-EpoxideN 2-Deoxyguanosine Adduct Induces Mutations at Multiple Sites in DNA von Pavel Kramata, Barbara Zajc, Jane M. Sayer, Donald M. Jerina, Caroline S.-J. Wei

Volltext

A Single Site-specific trans-Opened 7,8,9,10-Tetrahydrobenzo[a]pyrene 7,8-Diol 9,10-EpoxideN2-Deoxyguanosine Adduct Induces Mutations at Multiple Sites in DNA210 von Kramata, Pavel, Zajc, Barbara, Sayer, Jane M., Jerina, Donald M., Wei, Caroline S.-J.

Volltext

A single site-specific trans-opened 7,8,9,10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct induces mutations at multiple sites in DNA von Kramata, Pavel, Zajc, Barbara, Sayer, Jane M, Jerina, Donald M, Wei, Caroline S-J

Volltext

A Single Site-specific trans-Opened 7,8,9,10-Tetrahydrobenzo[a]pyrene 7,8-Diol 9,10-EpoxideN2-Deoxyguanosine Adduct Induces Mutations at Multiple Sites in DNA von Kramata, Pavel, Zajc, Barbara, Sayer, Jane M., Jerina, Donald M., Wei, Caroline S.-J.

Volltext

Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase ζ in vitro von SIMHADRI, Srilatha, KRAMATA, Pavel, ZAJC, Barbara, SAYER, Jane M, JERINA, Donald M, HINKLE, David C, WEI, Caroline S.-J

Volltext

Dose-dependent differences in the mutational profiles of (-)-(1R,2S,3S,4R)-3,4-dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene and its less carcinogenic enantiomer von WEI, S.-J. C, CHANG, R. L, CUI, X. X, MERKLER, K. A, WONG, C.-Q, YAGI, H, JERINA, D. M, CONNEY, A. H

Volltext

Does-Dependent Differences in the Profile of Mutations Induced by an Ultimate Carcinogen from Benzo[a]pyrene von S.-J. Caroline Wei, Richard L. Chang, Ching-Quo Wong, Niraja Bhachech, Xiao Xing Cui, Ewa Hennig, Haruhiko Yagi, Jane M. Sayer, Donald M. Jerina, Bradley D. Preston, Allan H. Conney

Volltext

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders von Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Bergen, Sarah E., Cai, Guiqing, Chambert, Kimberly D., Chen, Eric Y.H., Cloninger, C. Robert, Cohen, David, Cormican, Paul, Djurovic, Srdjan, Drapeau, Elodie, Durmishi, Naser, Genovese, Giulio, Herms, Stefan, Hofman, Andrea, Kalaydjieva, Luba, Kim, Yunjung, Kuzelova-Ptackova, Hana, Liang, Kung-Yee, Lönnqvist, Jouko, Maher, Brion S., Meier, Sandra, Milanova, Vihra, Parkhomenko, Elena, Paunio, Tiina, Purcell, Shaun M., Quested, Digby, Rasmussen, Henrik B., Richards, Alexander L., Roussos, Panos, Sim, Kang, So, Hon-Cheong, Strengman, Eric, Strohmaier, Jana, Svrakic, Dragan M., Tosato, Sarah, Weiser, Mark, Zimprich, Fritz, Wray, Naomi R., Stefansson, Kari, Visscher, Peter M., Liu, Jianjun, McQuillin, Andrew, Rujescu, Dan, Sullivan, Patrick F., Barroso, Ines, Mathew, Christopher G., Trembath, Richard C., Su, Zhan, Bumpstead, Suzannah J., Gillman, Matthew, McCann, Owen T., Iyegbe, Conrad, Milani, Lili, Palotie, Aarno, Sanders, Alan R., Bramon, Elvira, Lee, Jimmy, Breen, Gerome, Whitehead Pavlides, Jennifer M., Pedersen, Carsten Bøcker, Bøen, Erlend, Coryell, William, Dobbyn, Amanda L., Garnham, Julie, Pedersen, Marianne Giørtz, Gordon-Smith, Katherine, Kupka, Ralph, Martinsson, Lina, McKay, James D., Meng, Fan, Mullins, Niamh, Rivera, Margarita, Shehktman, Tatyana, Spijker, Anne T., Streit, Fabian, Vedder, Helmut, Weickert, Thomas W., Zandi, Peter, Zöllner, Sebastian, Kogevinas, Manolis, Nöthen, Markus M., Smeland, Olav B., Andreassen, Ole A., Abdellaoui, Abdel, Andlauer, Till F.M., Eley, Thalia C., Lind, Penelope A., Mostafavi, Sara, Smith, Daniel J., Wellmann, Jürgen, Hayward, Caroline, Schaefer, Catherine, Boomsma, Dorret I., Willemsen, Gonneke, Teumer, Alexander, Van der Auwera, Sandra, Blokland, Gabriëlla A.M., Plath, Niels

Volltext

VGF function in depression and antidepressant efficacy von Jiang, C, Lin, W-J, Sadahiro, M, Labonté, B, Menard, C, Pfau, M L, Tamminga, C A, Turecki, G, Nestler, E J, Russo, S J, Salton, S R

Volltext

Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia von Yougbaré, Issaka, Tai, Wei-She, Zdravic, Darko, Oswald, Brigitta Elaine, Lang, Sean, Zhu, Guangheng, Leong-Poi, Howard, Qu, Dawei, Yu, Lisa, Dunk, Caroline, Zhang, Jianhong, Sled, John G., Lye, Stephen J., Brkić, Jelena, Peng, Chun, Höglund, Petter, Croy, B. Anne, Adamson, S. Lee, Wen, Xiao-Yan, Stewart, Duncan J., Freedman, John, Ni, Heyu

Volltext

Mapping the human genetic architecture of COVID-19 von Niemi, Mari E. K, Karjalainen, Juha, Liao, Rachel G, Neale, Benjamin M, Daly, Mark, Ganna, Andrea

Volltext

Effectiveness of mRNA Covid-19 Vaccine among U.S. Health Care Personnel von Pilishvili, Tamara, Gierke, Ryan, Fleming-Dutra, Katherine E, Farrar, Jennifer L, Mohr, Nicholas M, Talan, David A, Krishnadasan, Anusha, Harland, Karisa K, Smithline, Howard A, Hou, Peter C, Lee, Lilly C, Lim, Stephen C, Moran, Gregory J, Krebs, Elizabeth, Steele, Mark T, Beiser, David G, Faine, Brett, Haran, John P, Nandi, Utsav, Schrading, Walter A, Chinnock, Brian, Henning, Daniel J, Lovecchio, Frank, Lee, Jane, Barter, Devra, Brackney, Monica, Fridkin, Scott K, Marceaux-Galli, Kaytlynn, Lim, Sarah, Phipps, Erin C, Dumyati, Ghinwa, Pierce, Rebecca, Markus, Tiffanie M, Anderson, Deverick J, Debes, Amanda K, Lin, Michael Y, Mayer, Jeanmarie, Kwon, Jennie H, Safdar, Nasia, Fischer, Marc, Singleton, Rosalyn, Chea, Nora, Magill, Shelley S, Verani, Jennifer R, Schrag, Stephanie J

Volltext

Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients With Heart Failure and Atrial Fibrillation: Results from the RAFT-AF trial von Parkash, Ratika, Wells, George A., Rouleau, Jean, Talajic, Mario, Essebag, Vidal, Skanes, Allan, Wilton, Stephen B., Verma, Atul, Healey, Jeffrey S., Sterns, Laurence, Bennett, Matthew, Roux, Jean-Francois, Rivard, Lena, Leong-Sit, Peter, Jensen-Urstad, Mats, Jolly, Umjeet, Philippon, Francois, Sapp, John L., Tang, Anthony S.L.

Volltext

ORthopaedic trauma hospital outcomes - Patient operative delays (ORTHOPOD) Study: The management of day-case orthopaedic trauma in the United Kingdom von Eardley, William P.G., Bowe, David, Gunn, Christopher, Le, Ha Phuong Do, Evans, Ashish, Diamond, Owen, King, Samuel, Lin, Benjamin, Davoudi, Kaveh, Raghuvanshi, Manav, Buddhdev, Pranai, Karam, Edward, Jayadeep, JS, Mazur, Karolina, Ibrahim, Amr, Gopal, Prasanth, Kennedy, Matthew, Oyekan, Adekinte, Raad, Marjan, Raut, Pramin, Gorvett, Alexander, Tinning, Craig, Chaturvedi, Abhishek, Alsawada, Osama, Vasarhelyi, Ferenc, Ardolino, Toni, Gouda, Joe, Ravi, Sanjeev Musuvathy, Imam, Sam, Tunstall, Charlotte, Holmes, Benjamin, Nichols, Jennifer, Thiagarajan, Aarthi, Rageeb, Peter Morad, Dong, Huan, Bawa, Akshdeep, Burden, Eleanor, Johnson-Lynn, Sarah, Mundy, Gary, Hussainy, Haydar Al, Jamalfar, Aral, Alcock, Liam, Koziara, Michal, Ollivere, Benjamin, Jamal, Bilal, Bell, Stuart, Wilson, Victoria, Chapman, Laura, Beaven, Alastair, Elzawahry, Ahmed, Trew, Christopher, Neo, Chryssa, Ashwood, Neil, Eyre-Brook, Alistair, Watts, Anna, Fullarton, Mairi, Thomas, Ellen, Williams, Mark, Bell, Katrina, Lum, Joann, Ford, David, Guryel, Enis, McLean, Elizabeth, Donovan, Richard, Diamond, Owen, Matthews, Scott, Zaheen, Humayoon, Islam, Saad, Theivendran, Kanthan, Sanghera, Ranjodh, Robinson, Karen, Fong, Angus, McGregor-Riley, Jonathan, Elhassan, Almutasim, Qazzaz, Layth, Mohamed, Muawia, Poole, William, Trompeter, Alex, Beer, Alexander, Green, Stephen, Rowland, David, O'Donnell, Janine, Edwards, Taff, Al-Habsi, Ruqaiya, Wong, Matthew Lynch, Patil, Sunit, Farhan-Alanie, Muhamed M, Larsen, Matthew P, Fang Soh, Terrence Chi, Doorgakant, Ashtin, Yogeswaran, Apimaan, Little, Max, Deakin, Sue, Douglas, Trixie, Atkinson, Kate V, Jamal, Shazil, Thomas, Terin, Pillai, Anand, Akkena, Sudheer, Lankester, Benedict

Volltext

Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus von Stacey, David, Chen, Lingyan, Stanczyk, Paulina J., Howson, Joanna M. M., Mason, Amy M., Burgess, Stephen, MacDonald, Stephen, Langdown, Jonathan, McKinney, Harriett, Downes, Kate, Farahi, Neda, Peters, James E., Basu, Saonli, Pankow, James S., Tang, Weihong, Pankratz, Nathan, Sabater-Lleal, Maria, de Vries, Paul S., Smith, Nicholas L., Gelinas, Amy D., Schneider, Daniel J., Janjic, Nebojsa, Samani, Nilesh J., Ye, Shu, Summers, Charlotte, Chilvers, Edwin R., Danesh, John, Paul, Dirk S.

Volltext

Genetic Implication of a Novel Thiamine Transporter in Human Hypertension von Zhang, Kuixing, MD, PhD, Huentelman, Matthew J., PhD, Rao, Fangwen, MD, Sun, Eric I., PhD, Corneveaux, Jason J., PhD, Schork, Andrew J., BS, Wei, Zhiyun, PhD, Waalen, Jill, MD, MPH, Miramontes-Gonzalez, Jose Pablo, MD, PhD, Hightower, C. Makena, PhD, Maihofer, Adam X., BS, Mahata, Manjula, PhD, Pastinen, Tomi, PhD, Ehret, Georg B., MD, Schork, Nicholas J., PhD, Eskin, Eleazar, PhD, Nievergelt, Caroline M., PhD, Saier, Milton H., PhD, O'Connor, Daniel T., MD

Volltext

Dose-dependent mutation profile in the c-Ha-ras proto-oncogene of skin tumors in mice initiated with benzo[a]pyrene von Wei, Shu-Jing Caroline, Chang, Richard L., Merkler, Kathleen A., Gwynne, Mark, Cui, Xiao Xing, Murthy, Bindu, Huang, Mou-Tuan, Xie, Jian-Guo, Lu, Yao-Ping, Lou, You-Rong, Jerina, Donald M., Conney, Allan H.

Volltext