Flavone inspired discovery of benzylidenebenzofuran-3(2H)-ones (aurones) as potent inhibitors of human protein kinase CK2 von Protopopov, M.V., Vdovin, V.S., Starosyla, S.A., Borysenko, I.P., Prykhod'ko, A.O., Lukashov, S.S., Bilokin, Y.V., Bdzhola, V.G., Yarmoluk, S.M.

Volltext

Evaluation of in vitro activity and SAR study of the novel hetarylamino-3-aryl-1H-indazole derivatives as inhibitors of protein kinase CK2 von Protopopov, M. V., Vdovin, V. S., Lukashov, S. S., Ostrynska, O. V., Borysenko, I. P., Borovykov, O. V., Starosyla, S. A., Bilokin, Y. V., Kukharenko, O. P., Bdzhola, V. G., Yarmoluk, S. M.

Volltext

Identification of membrane proteins as potential drug targets in Escherichia coli ATCC 25922 using in silico approaches von Koleiev, I. M., Starosyla, S. A., Protopopov, M. V., Volynets, G. P., Sapelkin, V. M., Pletnova, L. V., Syniugin, A. R., Kachaput, N. O., Matiushok, V. I., Bdzhola, V. G., Yarmoluk, S. M.

Volltext

The synthesis of 5-hetarylamino-3-aryl-1H-indazoles as inhibitors of protein kinase CK2 von Protopopov, M. V., Vdovin, V. S., Lukashov, S. S., Ostrynska, O. V., Borysenko, I. P., Borovykov, O. V., Starosyla, S. A., Bilokin, Y. V., Kukharenko, O. P., Bdzhola, V. G., Yarmoluk, S. M.

Volltext

Identification of 4‐methoxythieno[2,3‐d]pyrimidines as FGFR1 Inhibitors von Kotey, I. M., Protopopov, M. V., Starosyla, S. A., Balanda, A. O., Pletnova, L. V., Prykhod'ko, A. O., Bdzhola, V. G., Yarmoluk, S. M.

Volltext

Search of protein kinase CK2 inhibitors based on purine-2,6-diones derivatives von M. V. Protopopov, O. V. Ostrynska, D. H. Ivanchenko, S. A. Starosyla, V. G. Bdzhola, M. I. Romanenko, S. M. Yarmoluk

Volltext

Hit identification of CK2 inhibitors by virtual screening von Protopopov, M. V., Starosyla, S. A., Borovykov, O. V., Sapelkin, V. N., Bilokin, Y. V., Bdzhola, V. G., Yarmoluk, S. M.

Volltext

Discovery of potent anti–tuberculosis agents targeting aminoacyl–tRNA synthetases von Volynets, G. P., Starosyla, S. A., Bdzhola, V. G., Yarmoluk, S. M., Tukalo, M. A.

Volltext

Development of receptor-based protein kinase Cβ (PKCβ) pharmacophore model for the search of inhibitors with potential activity against acute respiratory distress syndrome (ARDS) von Starosyla, S. A., Volynets, G. P., Protopopov, M. V., Koleiev, I. M., Bdzhola, V. G., Yarmoluk, S. M.

Volltext

Discovery of novel antituberculosis agents among 3-phenyl-5-(1-phenyl-1H-[1,2,3]triazol-4-yl)-[1,2,4]oxadiazole derivatives targeting aminoacyl-tRNA synthetases von Rybak, Mariia Yu, Balanda, Anatoliy O., Yatsyshyna, Anna P., Kotey, Igor. M., Starosyla, Sergiy A., Bdzhola, Volodymyr G., Lukash, Lubov L., Yarmoluk, Sergiy M., Tukalo, Michael A., Volynets, Galyna P.

Volltext

Benzaldehyde thiosemicarbazone derivatives against replicating and nonreplicating Mycobacterium tuberculosis von Volynets, Galyna P., Tukalo, Michail A., Bdzhola, Volodymyr G., Derkach, Nataliia M., Gumeniuk, Mykola I., Tarnavskiy, Sergiy S., Starosyla, Sergiy A., Yarmoluk, Sergiy M.

Volltext

Identification of apoptosis signal-regulating kinase 1 (ASK1) inhibitors among the derivatives of benzothiazol-2-yl-3-hydroxy-5-phenyl-1,5-dihydro-pyrrol-2-one von Starosyla, Sergiy A., Volynets, Galyna P., Lukashov, Sergiy S., Gorbatiuk, Oksana B., Golub, Andriy G., Bdzhola, Volodymyr G., Yarmoluk, Sergiy M.

Volltext

The Influence of Flavonoid Compositions on Nrf2 Transcription Factor Expression in Case of Infections Triggered by Influenza A Virus and Transmissible Gastroenteritis Coronavirus von Arkhypova, Maryna, Deriabin, Oleg, Trokhymchuk, Tetiana, Starosyla, Daria, Atamaniuk, Viktor, Zavelevich, Michael, Vialykh, Zhanna, Rybalko, Svitlana, Galkin, Alexander

Volltext

Biological Evaluation of Medical Devices in the Form of Suppositories for Rectal and Vaginal Use von Dmytrenko, Oleksandra, Arkhypova, Maryna, Starosyla, Darya, Rybalko, Svitlana, Gevorkyan, Michael, Galkin, Alexander

Volltext

Computer-aided design of muscarinic acetylcholine receptor M3 inhibitors: Promising compounds among trifluoromethyl containing hexahydropyrimidinones/thiones von Nyporko, Alex, Tsymbalyuk, Olga, Voiteshenko, Ivan, Starosyla, Sergiy, Protopopov, Mykola, Bdzhola, Volodymyr

Volltext

Discovery of potent anti-tuberculosis agents targeting leucyl-tRNA synthetase von Gudzera, Olga I., Golub, Andriy G., Bdzhola, Volodymyr G., Volynets, Galyna P., Lukashov, Sergiy S., Kovalenko, Oksana P., Kriklivyi, Ivan A., Yaremchuk, Anna D., Starosyla, Sergiy A., Yarmoluk, Sergiy M., Tukalo, Michail A.

Volltext

Pharmacophore modeling, docking and molecular dynamics simulation for identification of novel human protein kinase C beta (PKCβ) inhibitors von Starosyla, Sergiy A., Volynets, Galyna P., Protopopov, Mykola V., Bdzhola, Volodymyr G., Pashevin, Denis O., Polishchuk, Valentyna O., Kozak, Taisiia O., Stroi, Dmytro O., Dosenko, Victor E., Yarmoluk, Sergiy M.

Volltext

3DProtDTA: a deep learning model for drug-target affinity prediction based on residue-level protein graphs von Voitsitskyi, Taras, Stratiichuk, Roman, Koleiev, Ihor, Popryho, Leonid, Ostrovsky, Zakhar, Henitsoi, Pavlo, Khropachov, Ivan, Vozniak, Volodymyr, Zhytar, Roman, Nechepurenko, Diana, Yesylevskyy, Semen, Nafiiev, Alan, Starosyla, Serhii

Volltext

Augmenting a training dataset of the generative diffusion model for molecular docking with artificial binding pockets von Voitsitskyi, Taras, Bdzhola, Volodymyr, Stratiichuk, Roman, Koleiev, Ihor, Ostrovsky, Zakhar, Vozniak, Volodymyr, Khropachov, Ivan, Henitsoi, Pavlo, Popryho, Leonid, Zhytar, Roman, Yesylevskyy, Semen, Nafiiev, Alan, Starosyla, Serhii

Volltext

Dual-targeted hit identification using pharmacophore screening von Volynets, Galyna P., Starosyla, Sergiy A., Rybak, Mariia Yu, Bdzhola, Volodymyr G., Kovalenko, Oksana P., Vdovin, Vasyl S., Yarmoluk, Sergiy M., Tukalo, Michail A.

Volltext