X-ray and Nuclear Magnetic Resonance (NMR) Studies of Signalizing the Tripeptide Sequence (Tyr-D-Ala-Phe) of Dermorphin and Deltorphins I and II. Comparative Analysis in the Liquid... von Słabicki, Mikołaj M, Potrzebowski, Marek J, Bujacz, Grzegorz, Olejniczak, Sebastian, Olczak, Jacek

Volltext

Anti‐SARS‐CoV‐2 activity of targeted kinase inhibitors: Repurposing clinically available drugs for COVID‐19 therapy von Boytz, RuthMabel, Słabicki, Mikołaj, Ramaswamy, Sita, Patten, J. J., Zou, Charles, Meng, Chengcheng, Hurst, Brett L., Wang, Jinhua, Nowak, Radosław P., Yang, Priscilla L., Sattler, Martin, Stone, Richard M., Griffin, James D., Gray, Nathanael S., Gummuluru, Suryaram, Davey, Robert A., Weisberg, Ellen

Volltext

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K von Słabicki, Mikołaj, Kozicka, Zuzanna, Petzold, Georg, Li, Yen-Der, Manojkumar, Manisha, Bunker, Richard D., Donovan, Katherine A., Sievers, Quinlan L., Koeppel, Jonas, Suchyta, Dakota, Sperling, Adam S., Fink, Emma C., Gasser, Jessica A., Wang, Li R., Corsello, Steven M., Sellar, Rob S., Jan, Max, Gillingham, Dennis, Scholl, Claudia, Fröhling, Stefan, Golub, Todd R., Fischer, Eric S., Thomä, Nicolas H., Ebert, Benjamin L.

Volltext

Small-molecule-induced polymerization triggers degradation of BCL6 von Słabicki, Mikołaj, Yoon, Hojong, Koeppel, Jonas, Nitsch, Lena, Roy Burman, Shourya S., Di Genua, Cristina, Donovan, Katherine A., Sperling, Adam S., Hunkeler, Moritz, Tsai, Jonathan M., Sharma, Rohan, Guirguis, Andrew, Zou, Charles, Chudasama, Priya, Gasser, Jessica A., Miller, Peter G., Scholl, Claudia, Fröhling, Stefan, Nowak, Radosław P., Fischer, Eric S., Ebert, Benjamin L.

Volltext

A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia von Słabicki, Mikołaj, Theis, Mirko, Krastev, Dragomir B, Samsonov, Sergey, Mundwiller, Emeline, Junqueira, Magno, Paszkowski-Rogacz, Maciej, Teyra, Joan, Heninger, Anne-Kristin, Poser, Ina, Prieur, Fabienne, Truchetto, Jérémy, Confavreux, Christian, Marelli, Cécilia, Durr, Alexandra, Camdessanche, Jean Philippe, Brice, Alexis, Shevchenko, Andrej, Pisabarro, M Teresa, Stevanin, Giovanni, Buchholz, Frank

Volltext

Polymerization of ZBTB transcription factors regulates chromatin occupancy von Park, Paul M.C., Park, Jiho, Brown, Jared, Hunkeler, Moritz, Roy Burman, Shourya S., Donovan, Katherine A., Yoon, Hojong, Nowak, Radosław P., Słabicki, Mikołaj, Ebert, Benjamin L., Fischer, Eric S.

Volltext

Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis von Kim, Peter Geon, Niroula, Abhishek, Shkolnik, Veronica, McConkey, Marie, Lin, Amy E, Słabicki, Mikołaj, Kemp, John P, Bick, Alexander, Gibson, Christopher J, Griffin, Gabriel, Sekar, Aswin, Brooks, Daniel J, Wong, Waihay J, Cohen, Drew N, Uddin, Md Mesbah, Shin, Wesley J, Pirruccello, James, Tsai, Jonathan M, Agrawal, Mridul, Kiel, Douglas P, Bouxsein, Mary L, Richards, J Brent, Evans, David M, Wein, Marc N, Charles, Julia F, Jaiswal, Siddhartha, Natarajan, Pradeep, Ebert, Benjamin L

Volltext

UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability von Tsai, Jonathan M, Aguirre, Jacob D, Li, Yen-Der, Brown, Jared, Focht, Vivian, Kater, Lukas, Kempf, Georg, Sandoval, Brittany, Schmitt, Stefan, Rutter, Justine C, Galli, Pius, Sandate, Colby R, Cutler, Jevon A, Zou, Charles, Donovan, Katherine A, Lumpkin, Ryan J, Cavadini, Simone, Park, Paul M C, Sievers, Quinlan, Hatton, Charlie, Ener, Elizabeth, Regalado, Brandon D, Sperling, Micah T, Słabicki, Mikołaj, Kim, Jeonghyeon, Zon, Rebecca, Zhang, Zinan, Miller, Peter G, Belizaire, Roger, Sperling, Adam S, Fischer, Eric S, Irizarry, Rafael, Armstrong, Scott A, Thomä, Nicolas H, Ebert, Benjamin L

Volltext

Drug-perturbation-based stratification of blood cancer von Dietrich, Sascha, Oleś, Małgorzata, Lu, Junyan, Sellner, Leopold, Anders, Simon, Velten, Britta, Wu, Bian, Hüllein, Jennifer, da Silva Liberio, Michelle, Walther, Tatjana, Wagner, Lena, Rabe, Sophie, Ghidelli-Disse, Sonja, Bantscheff, Marcus, Oleś, Andrzej K, Słabicki, Mikołaj, Mock, Andreas, Oakes, Christopher C, Wang, Shihui, Oppermann, Sina, Lukas, Marina, Kim, Vladislav, Sill, Martin, Benner, Axel, Jauch, Anna, Sutton, Lesley Ann, Young, Emma, Rosenquist, Richard, Liu, Xiyang, Jethwa, Alexander, Lee, Kwang Seok, Lewis, Joe, Putzker, Kerstin, Lutz, Christoph, Rossi, Davide, Mokhir, Andriy, Oellerich, Thomas, Zirlik, Katja, Herling, Marco, Nguyen-Khac, Florence, Plass, Christoph, Andersson, Emma, Mustjoki, Satu, von Kalle, Christof, Ho, Anthony D, Hensel, Manfred, Dürig, Jan, Ringshausen, Ingo, Zapatka, Marc, Huber, Wolfgang, Zenz, Thorsten

Volltext

Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor von Huang, Yung-Hsin, Chen, Chun-Wei, Sundaramurthy, Venkatasubramaniam, Słabicki, Mikołaj, Hao, Dapeng, Watson, Caroline J, Tovy, Ayala, Reyes, Jaime M, Dakhova, Olga, Crovetti, Brielle R, Galonska, Christina, Lee, Minjung, Brunetti, Lorenzo, Zhou, Yubin, Tatton-Brown, Katrina, Huang, Yun, Cheng, Xiaodong, Meissner, Alexander, Valk, Peter J M, Van Maldergem, Lionel, Sanders, Mathijs A, Blundell, Jamie R, Li, Wei, Ebert, Benjamin L, Goodell, Margaret A

Volltext

LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding von Ludwig, Kerstin U., Schmithausen, Ricarda M., Li, David, Jacobs, Max L., Hollstein, Ronja, Blumenstock, Katja, Liebing, Jana, Słabicki, Mikołaj, Ben-Shmuel, Amir, Israeli, Ofir, Weiss, Shay, Ebert, Thomas S., Paran, Nir, Rüdiger, Wibke, Wilbring, Gero, Feldman, David, Lippke, Bärbel, Ishorst, Nina, Hochfeld, Lara M., Beins, Eva C., Kaltheuner, Ines H., Schmitz, Maximilian, Wöhler, Aliona, Döhla, Manuel, Sib, Esther, Jentzsch, Marius, Moench, Eva-Maria C., Borrajo, Jacob D., Strecker, Jonathan, Reinhardt, Julia, Cleary, Brian, Geyer, Matthias, Hölzel, Michael, Macrae, Rhiannon, Nöthen, Markus M., Hoffmann, Per, Exner, Martin, Regev, Aviv, Zhang, Feng, Schmid-Burgk, Jonathan L.

Volltext

Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry von Sarott, Roman C., You, Inchul, Li, Yen-Der, Toenjes, Sean T., Donovan, Katherine A., Seo, Pooreum, Ordonez, Martha, Byun, Woong Sub, Hassan, Muhammad Murtaza, Wachter, Franziska, Chouchani, Edward T., Słabicki, Mikołaj, Fischer, Eric S., Ebert, Benjamin L., Hinshaw, Stephen M., Gray, Nathanael S.

Volltext

PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy von Miller, Peter G., Sperling, Adam S., Mayerhofer, Christina, McConkey, Marie E., Ellegast, Jana M., Da Silva, Carmen, Cohen, Drew N., Wang, Chuqi, Sharda, Azeem, Yan, Ni, Saha, Subha, Schluter, Cameron, Schechter, Ilexa, Słabicki, Mikołaj, Sandoval, Brittany, Kahn, Josephine, Boettcher, Steffen, Gibson, Christopher J., Scadden, David T., Stegmaier, Kimberly, Bhatt, Shruti, Lindsley, R. Coleman, Ebert, Benjamin L.

Volltext

DECIPHER pooled shRNA library screen identifies PP2A and FGFR signaling as potential therapeutic targets for diffuse intrinsic pontine gliomas von Schramm, Kathrin, Iskar, Murat, Statz, Britta, Jäger, Natalie, Haag, Daniel, Słabicki, Mikołaj, Pfister, Stefan M, Zapatka, Marc, Gronych, Jan, Jones, David T W, Lichter, Peter

Volltext

Genetic retargeting of E3 ligases to enhance CAR T cell therapy von Lane, Isabel C., Kembuan, Gabriele, Carreiro, Jeannie, Kann, Michael C., Lin, William, Bouffard, Amanda A., Kreuzer, Johannes, Morris, Robert, Schneider, Emily M., Kim, Joanna Y., Zou, Charles, Salas-Benito, Diego, Gasser, Jessica A., Leick, Mark B., Słabicki, Mikołaj, Haas, Wilhelm, Maus, Marcela V., Jan, Max

Volltext

Template-assisted covalent modification underlies activity of covalent molecular glues von Li, Yen-Der, Ma, Michelle W., Hassan, Muhammad Murtaza, Hunkeler, Moritz, Teng, Mingxing, Puvar, Kedar, Rutter, Justine C., Lumpkin, Ryan J., Sandoval, Brittany, Jin, Cyrus Y., Schmoker, Anna M., Ficarro, Scott B., Cheong, Hakyung, Metivier, Rebecca J., Wang, Michelle Y., Xu, Shawn, Byun, Woong Sub, Groendyke, Brian J., You, Inchul, Sigua, Logan H., Tavares, Isidoro, Zou, Charles, Tsai, Jonathan M., Park, Paul M. C., Yoon, Hojong, Majewski, Felix C., Sperling, Haniya T., Marto, Jarrod A., Qi, Jun, Nowak, Radosław P., Donovan, Katherine A., Słabicki, Mikołaj, Gray, Nathanael S., Fischer, Eric S., Ebert, Benjamin L.

Volltext

The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein von Zou, Charles, Yoon, Hojong, Park, Paul M.C., Patten, J.J., Pellman, Jesse, Carreiro, Jeannie, Tsai, Jonathan M., Li, Yen-Der, Roy Burman, Shourya S., Donovan, Katherine A., Gasser, Jessica, Sperling, Adam S., Nowak, Radosław P., Fischer, Eric S., Davey, Robert A., Ebert, Benjamin L., Słabicki, Mikołaj

Volltext

Author Correction: LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding von Ludwig, Kerstin U., Schmithausen, Ricarda M., Li, David, Jacobs, Max L., Hollstein, Ronja, Blumenstock, Katja, Liebing, Jana, Słabicki, Mikołaj, Ben-Shmuel, Amir, Israeli, Ofir, Weiss, Shay, Ebert, Thomas S., Paran, Nir, Rüdiger, Wibke, Wilbring, Gero, Feldman, David, Lippke, Bärbel, Ishorst, Nina, Hochfeld, Lara M., Beins, Eva C., Kaltheuner, Ines H., Schmitz, Maximilian, Wöhler, Aliona, Döhla, Manuel, Sib, Esther, Jentzsch, Marius, Moench, Eva-Maria C., Borrajo, Jacob D., Strecker, Jonathan, Reinhardt, Julia, Cleary, Brian, Geyer, Matthias, Hölzel, Michael, Macrae, Rhiannon, Nöthen, Markus M., Hoffmann, Per, Exner, Martin, Regev, Aviv, Zhang, Feng, Schmid-Burgk, Jonathan L.

Volltext

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma von Jethwa, Alexander, Słabicki, Mikołaj, Hüllein, Jennifer, Jentzsch, Marius, Dalal, Vineet, Rabe, Sophie, Wagner, Lena, Walther, Tatjana, Klapper, Wolfram, Bohnenberger, Hanibal, Rettel, Mandy, Lu, Junyan, Smits, Arne H., Stein, Frank, Savitski, Mikhail M., Huber, Wolfgang, Aylon, Yael, Oren, Moshe, Zenz, Thorsten, MMML Network Project

Volltext

LAMP-Seq: Sensitive, Scalable, and Multiplexable COVID-19 Diagnostics Using Molecular Barcoding von Ludwig, Kerstin U., Schmithausen, Ricarda M., Li, David, Jacobs, Max L., Hollstein, Ronja, Blumenstock, Katja, Liebing, Jana, Słabicki, Mikołaj, Ben-Shmuel, Amir, Israeli, Ofir, Weiss, Shay, Ebert, Thomas S., Paran, Nir, Rüdiger, Wibke, Wilbring, Gero, Feldman, David, Lippke, Bärbel, Ishorst, Nina, Hochfeld, Lara M., Beins, Eva C., Kaltheuner, Ines H., Schmitz, Maximilian, Wöhler, Aliona, Döhla, Manuel, Sib, Esther, Jentzsch, Marius, Borrajo, Jacob D., Strecker, Jonathan, Reinhardt, Julia, Cleary, Brian, Geyer, Matthias, Hölzel, Michael, Macrae, Rhiannon, Nöthen, Markus M., Hoffmann, Per, Exner, Martin, Regev, Aviv, Zhang, Feng, Schmid-Burgk, Jonathan L.

Volltext