Different Genetic Signatures of Small‐Cell Lung Cancer Characterize Anti‐GABABR and Anti‐Hu Paraneoplastic Neurological Syndromes von Vogrig, Alberto, Pegat, Antoine, Macarena Villagrán‐García, Wucher, Valentin, Attignon, Valéry, Sohier, Emilie, Brevet, Marie, Rogemond, Veronique, Anne‐Laurie Pinto, Sergio Muñiz‐Castrillo, Peter, Elise, Melisse, Robert, Picard, Géraldine, Hopes, Lucie, Psimaras, Dimitri, Terra, Anthony, Perrin, Corinne, Cogne, Dominique, Severine Tabone‐Eglinger, Martinez, Séverine, Jury, Delphine, Valantin, Julie, Gadot, Nicolas, Jessie Auclair‐Perrossier, Viari, Alain, Dubois, Bertrand, Desestret, Virginie, Honnorat, Jérôme

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Immunomic longitudinal profiling of the NeoPembrOv trial identifies drivers of immunoresistance in high-grade ovarian carcinoma von Le Saux, Olivia, Ardin, Maude, Berthet, Justine, Barrin, Sarah, Bourhis, Morgane, Cinier, Justine, Lounici, Yasmine, Treilleux, Isabelle, Just, Pierre-Alexandre, Bataillon, Guillaume, Savoye, Aude-Marie, Mouret-Reynier, Marie-Ange, Coquan, Elodie, Derbel, Olfa, Jeay, Louis, Bouizaguen, Suliman, Labidi-Galy, Intidhar, Tabone-Eglinger, Séverine, Ferrari, Anthony, Thomas, Emilie, Ménétrier-Caux, Christine, Tartour, Eric, Galy-Fauroux, Isabelle, Stern, Marc-Henri, Terme, Magali, Caux, Christophe, Dubois, Bertrand, Ray-Coquard, Isabelle

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Added value of whole‐exome and RNA sequencing in advanced and refractory cancer patients with no molecular‐based treatment recommendation based on a 90‐gene panel von Dufresne, Armelle, Attignon, Valéry, Ferrari, Anthony, Tonon, Laurie, Boyault, Sandrine, Tabone‐Eglinger, Séverine, Cassier, Philippe, Trédan, Olivier, Corradini, Nadège, Vinceneux, Armelle, Swalduz, Aurélie, Viari, Alain, Chabaud, Sylvie, Pérol, David, Blay, Jean Yves, Saintigny, Pierre

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Niche anchorage and signaling through membrane‐bound Kit‐ligand/c‐kit receptor are kinase independent and imatinib insensitive von Tabone‐Eglinger, Séverine, Calderin‐Sollet, Zuleika, Pinon, Perrine, Aebischer, Nicole, Wehrle‐Haller, Monique, Jacquier, Marie‐Claude, Boettiger, David, Wehrle‐Haller, Bernhard

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KIT Mutations Induce Intracellular Retention and Activation of an Immature Form of the KIT Protein in Gastrointestinal Stromal Tumors von TABONE-EGLINGER, Séverine, SUBRA, Frédéric, EL SAYADI, Hiba, ALBERTI, Laurent, TABONE, Eric, MICHOT, Jean-Philippe, THEOU-ANTON, Nathalie, LEMOINE, Antoinette, BLAY, Jean-Yves, EMILE, Jean-Francois

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A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors von Marques Da Costa, Maria Eugénia, Zaidi, Sakina, Scoazec, Jean-Yves, Droit, Robin, Lim, Wan Ching, Marchais, Antonin, Salmon, Jerome, Cherkaoui, Sarah, Morscher, Raphael J., Laurent, Anouchka, Malinge, Sébastien, Mercher, Thomas, Tabone-Eglinger, Séverine, Goddard, Isabelle, Pflumio, Francoise, Calvo, Julien, Redini, Francoise, Entz-Werlé, Natacha, Soriano, Aroa, Villanueva, Alberto, Cairo, Stefano, Chastagner, Pascal, Moro, Massimo, Owens, Cormac, Casanova, Michela, Hladun-Alvaro, Raquel, Berlanga, Pablo, Daudigeos-Dubus, Estelle, Dessen, Philippe, Zitvogel, Laurence, Lacroix, Ludovic, Pierron, Gaelle, Delattre, Olivier, Schleiermacher, Gudrun, Surdez, Didier, Geoerger, Birgit

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Netrin-1 blockade inhibits tumor associated Myeloid-derived suppressor cells, cancer stemness and alleviates resistance to chemotherapy and immune checkpoint inhibitor von Ducarouge, Benjamin, Redavid, Anna-Rita, Victoor, Camille, Chira, Ruxanda, Fonseca, Aurélien, Hervieu, Maëva, Bergé, Roméo, Lengrand, Justine, Vieugué, Pauline, Neves, David, Goddard, Isabelle, Richaud, Mathieu, Laval, Pierre-Alexandre, Rama, Nicolas, Goldschneider, David, Paradisi, Andrea, Gourdin, Nicolas, Chabaud, Sylvie, Treilleux, Isabelle, Gadot, Nicolas, Ray-Coquard, Isabelle, Depil, Stéphane, Decaudin, Didier, Némati, Fariba, Marangoni, Elisabetta, Mery-Lamarche, Eliane, Génestie, Catherine, Tabone-Eglinger, Séverine, Devouassoux-Shisheboran, Mojgan, Moore, Kathryn J., Gibert, Benjamin, Mehlen, Patrick, Bernet, Agnes

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Gene expression patterns of hemizygous and heterozygous KIT mutations suggest distinct oncogenic pathways: a study in NIH3T3 cell lines and GIST samples von Bachet, Jean-Baptiste, Tabone-Eglinger, Séverine, Dessaux, Sophie, Besse, Anthony, Brahimi-Adouane, Sabrina, Emile, Jean-François, Blay, Jean-Yves, Alberti, Laurent

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Membrane‐bound Kit ligand regulates melanocyte adhesion and survival, providing physical interaction with an intraepithelial niche von Tabone‐Eglinger, Severine, Wehrle‐Haller, Monique, Aebischer, Nicole, Jacquier, Marie‐Claude, Wehrle‐Haller, Bernhard

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Dimerization of Kit-ligand and efficient cell-surface presentation requires a conserved Ser-Gly-Gly-Tyr motif in its transmembrane domain von Paulhe, Frédérique, Wehrle-Haller, Monique, Jacquier, Marie-Claude, Imhof, Beat A, Tabone-Eglinger, Séverine, Wehrle-Haller, Bernhard

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Staging of newly diagnosed Ewing sarcoma: Results of bone marrow aspiration and biopsy versus (18)FDG-PET/CT imaging for bone marrow involvement von Guinot, A., Tabone-Eglinger, S., Isnardi, V., Bahri, H., Surdez, D., Delattre, O., Pierron, G., Villemeur, M., Lapouble, E., Brahmi, M., Bouhamama, A., Corradini, N., Marec-Bérard, Perrine

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Incidence of Venous Thromboembolism in Patients With Newly Diagnosed Pancreatic Cancer and Factors Associated With Outcomes von Frere, Corinne, Bournet, Barbara, Gourgou, Sophie, Fraisse, Julien, Canivet, Cindy, Connors, Jean M., Buscail, Louis, Farge, Dominique, Bournet, Barbara, Canivet, Cindy, Buscail, Louis, Carrère, Nicolas, Muscari, Fabrice, Suc, Bertrand, Guimbaud, Rosine, Couteau, Corinne, Deslandres, Marion, Rivera, Pascale, Laurenty, Anne-Pascale, Fares, Nadim, Barange, Karl, Selves, Janick, Gomez-Brouchet, Anne, Napoléon, Bertrand, Pujol, Bertrand, Fumex, Fabien, Desrame, Jérôme, Lefort, Christine, Lepilliez, Vincent, Gincul, Rodica, Artru, Pascal, Clavel, Léa, Lemaistre, Anne-Isabelle, Palazzo, Laurent, Cros, Jérôme, Tubiana, Sarah, Flori, Nicolas, Senesse, Pierre, Colombo, Pierre-Emmanuel, Samail-Scalzi, Emmanuelle, Portales, Fabienne, Gourgou, Sophie, Ga, Claire Honfo, Plassot, Carine, Fraisse, Julien, Bibeau, Frédéric, Ychou, Marc, Guibert, Pierre, Fouchardière, Christelle de la, Sarabi, Matthieu, Peyrat, Patrice, Tabone-Eglinger, Séverine, Renard, Caroline, Piessen, Guillaume, Truant, Stéphanie, Saudemont, Alain, Millet, Guillaume, Renaud, Florence, Leteurtre, Emmanuelle, Gele, Patrick, Assenat, Eric, Fabre, Jean-Michel, Souche, François-Régis, Dupuy, Marie, Gorce-Dupuy, Anne-Marie, Ramos, Jeanne, Seitz, Jean-François, Hardwigsen, Jean, Norguet-Monnereau, Emmanuelle, Grandval, Philippe, Duluc, Muriel, Figarella-Branger, Dominique, Vendrely, Véronique, Subtil, Clément, Terrebonne, Eric, Blanc, Jean-Frédéric, Buscail, Etienne, Merlio, Jean-Philippe, Farge, Dominique, Gornet, Jean-Marc, Geromin, Daniela, Vanbiervliet, Geoffroy, Frin, Anne-Claire, Ouvrier, Delphine, Saint-Paul, Marie-Christine, Berthelémy, Philippe, Fouad, Chelbabi, Garcia, Stéphane, Lesavre, Nathalie, Gasmi, Mohamed, Barthet, Marc, Cottet, Vanessa, Delpierre, Cyrille

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Effects of endoplasmic reticulum stressors on maturation and signaling of hemizygous and heterozygous wild-type and mutant forms of KIT von Brahimi-Adouane, Sabrina, Bachet, Jean-Baptiste, Tabone-Eglinger, Séverine, Subra, Frédéric, Capron, Claude, Blay, Jean-Yves, Emile, Jean-François

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Prognostic Value of KIT Exon 11 Deletions in GISTs von Emile, Jean-François, Tabone–Eglinger, Séverine, Théou–Anton, Nathalie, Lemoine, Antoinette

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Peripheral blood CD56bright NK cells respond to stem cell factor and adhere to its membrane‐bound form after upregulation of c‐kit von Pradier, Amandine, Tabone‐Eglinger, Severine, Huber, Vincent, Bosshard, Carine, Rigal, Emmanuel, Wehrle‐Haller, Bernhard, Roosnek, Eddy

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Abstract 3846: Imodi initiative: A novel holistic and integrative approach with patient-derived tumor models against pancreatic cancer von Iovanna, Juan, Dussetti, Nelson, Meyer-losic, Florence, Vacon, Françoise Le, Calvet, Loreley, Forraz, Nico, Dhondt, Kevin, Kuras, Mariana, Lautrette, Christophe, Tabone-Eglinger, Séverine, Vaglio, Philippe, Duchamp, Olivier

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MEDIPLEX: A phase 1 study of durvalumab (D) combined with pexidartinib (P) in patients (pts) with advanced pancreatic ductal adenocarcinoma (PDAC) and colorectal cancer (CRC) von Cassier, Philippe Alexandre, Garin, Gwenaelle, Eberst, Lauriane, Delord, Jean-Pierre, Chabaud, Sylvie, Terret, Catherine, Montane, Laure, Bidaux, Anne-Sophie, Laurent, Séverine, Jaubert, Lise, Ferlay, Celine, Bernardin, Mathilde, Tabone-Eglinger, Séverine, Gilles-Afchain, Laurence, Menetrier-Caux, Christine, Caux, Christophe, Treilleux, Isabelle, Pérol, David, Gomez-Roca, Carlos Alberto

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Incidence of Venous Thromboembolism in Patients With Newly Diagnosed Pancreatic Cancer and Factors Associated With Outcomes von Frere, Corinne, Bournet, Barbara, Gourgou, Sophie, Fraisse, Julien, Canivet, Cindy, Connors, Jean, Buscail, Louis, Farge, Dominique, Carrère, Nicolas, Muscari, Fabrice, Suc, Bertrand, Guimbaud, Rosine, Couteau, Corinne, Deslandres, Marion, Rivera, Pascale, Laurenty, Anne-Pascale, Fares, Nadim, Barange, Karl, Selves, Janick, Gomez-Brouchet, Anne, Napoléon, Bertrand, Pujol, Bertrand, Fumex, Fabien, Desrame, Jérôme, Lefort, Christine, Lepilliez, Vincent, Gincul, Rodica, Artru, Pascal, Clavel, Léa, Lemaistre, Anne-Isabelle, Palazzo, Laurent, Cros, Jérôme, Tubiana, Sarah, Flori, Nicolas, Senesse, Pierre, Colombo, Pierre-Emmanuel, Samail-Scalzi, Emmanuelle, Portales, Fabienne, Gourgou, Sophie, Ga, Claire Honfo, Plassot, Carine, Bibeau, Frédéric, Ychou, Marc, Guibert, Pierre, Fouchardière, Christelle de La, Sarabi, Matthieu, Peyrat, Patrice, Tabone-Eglinger, Séverine, Renard, Caroline, Piessen, Guillaume, Truant, Stéphanie, Saudemont, Alain, Millet, Guillaume, Renaud, Florence, Leteurtre, Emmanuelle, Gele, Patrick, Assenat, Eric, Fabre, Jean-Michel, Souche, François-Régis, Dupuy, Marie, Gorce-Dupuy, Anne-Marie, Ramos, Jeanne, Seitz, Jean-François, Hardwigsen, Jean, Norguet-Monnereau, Emmanuelle, Grandval, Philippe, Duluc, Muriel, Figarella-Branger, Dominique, Vendrely, Véronique, Subtil, Clément, Terrebonne, Eric, Blanc, Jean-Frédéric, Buscail, Etienne, Merlio, Jean-Philippe, Gornet, Jean-Marc, Geromin, Daniela, Vanbiervliet, Geoffroy, Frin, Anne-Claire, Ouvrier, Delphine, Saint-Paul, Marie-Christine, Berthelémy, Philippe, Fouad, Chelbabi, Garcia, Stéphane, Lesavre, Nathalie, Gasmi, Mohamed, Barthet, Marc, Cottet, Vanessa, Delpierre, Cyrille

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A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors von Marques Da Costa, Maria Eugénia, Zaidi, Sakina, Scoazec, Jean-Yves, Droit, Robin, Lim, Wan Ching, Marchais, Antonin, Salmon, Jerome, Cherkaoui, Sarah, Morscher, Raphael J, Laurent, Anouchka, Malinge, Sébastien, Mercher, Thomas, Tabone-Eglinger, Séverine, Goddard, Isabelle, Pflumio, Francoise, Calvo, Julien, Redini, Francoise, Entz-Werlé, Natacha, Soriano, Aroa, Villanueva, Alberto, Cairo, Stefano, Chastagner, Pascal, Moro, Massimo, Owens, Cormac, Casanova, Michela, Hladun-Alvaro, Raquel, Berlanga, Pablo, Daudigeos-Dubus, Estelle, Dessen, Philippe, Surdez, Didier

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PD-1 Blockade in Solid Tumors with Defects in Polymerase Epsilon von Rousseau, Benoit, Bieche, Ivan, Pasmant, Eric, Hamzaoui, Nadim, Leulliot, Nicolas, Michon, Lucas, de Reynies, Aurelien, Attignon, Valerie, Foote, Michael B, Masliah-Planchon, Julien, Svrcek, Magali, Cohen, Romain, Simmet, Victor, Augereau, Paule, Malka, David, Hollebecque, Antoine, Pouessel, Damien, Gomez-Roca, Carlos, Guimbaud, Rosine, Bruyas, Amandine, Guillet, Marielle, Grob, Jean-Jacques, Duluc, Muriel, Cousin, Sophie, de la Fouchardiere, Christelle, Flechon, Aude, Rolland, Frederic, Hiret, Sandrine, Saada-Bouzid, Esma, Bouche, Olivier, Andre, Thierry, Pannier, Diane, El Hajbi, Farid, Oudard, Stephane, Tournigand, Christophe, Soria, Jean-Charles, Champiat, Stephane, Gerber, Drew G, Stephens, Dennis, Lamendola-Essel, Michelle F, Maron, Steven B, Diplas, Bill H, Argiles, Guillem, Krishnan, Asha R, Tabone-Eglinger, Severine, Ferrari, Anthony, Segal, Neil H, Cercek, Andrea, Hoog-Labouret, Natalie, Legrand, Frederic, Simon, Clotilde, Lamrani-Ghaouti, Assia, Diaz, Luis A, Saintigny, Pierre, Chevret, Sylvie, Marabelle, Aurelien

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