DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid von Abrahams, Katherine A., Batt, Sarah M., Gurcha, Sudagar S., Veerapen, Natacha, Bashiri, Ghader, Besra, Gurdyal S.

Volltext

Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol von Zhang, Lu, Zhao, Yao, Gao, Yan, Wu, Lijie, Gao, Ruogu, Zhang, Qi, Wang, Yinan, Wu, Chengyao, Wu, Fangyu, Gurcha, Sudagar S, Veerapen, Natacha, Batt, Sarah M, Zhao, Wei, Qin, Ling, Yang, Xiuna, Wang, Manfu, Zhu, Yan, Zhang, Bing, Bi, Lijun, Zhang, Xian'en, Yang, Haitao, Guddat, Luke W, Xu, Wenqing, Wang, Quan, Li, Jun, Besra, Gurdyal S, Rao, Zihe

Volltext

Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome von Shenderov, Kevin, Barber, Daniel L, Mayer-Barber, Katrin D, Gurcha, Sudagar S, Jankovic, Dragana, Feng, Carl G, Oland, Sandy, Hieny, Sara, Caspar, Pat, Yamasaki, Sho, Lin, Xin, Ting, Jenny P-Y, Trinchieri, Giorgio, Besra, Gurdyal S, Cerundolo, Vincenzo, Sher, Alan

Volltext

The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth von Franklin, Aaron, Salgueiro, Vivian C., Layton, Abigail J., Sullivan, Rudi, Mize, Todd, Vázquez-Iniesta, Lucía, Benedict, Samuel T., Gurcha, Sudagar S., Anso, Itxaso, Besra, Gurdyal S., Banzhaf, Manuel, Lovering, Andrew L., Williams, Spencer J., Guerin, Marcelo E., Scott, Nichollas E., Prados-Rosales, Rafael, Lowe, Elisabeth C., Moynihan, Patrick J.

Volltext

Author Correction: The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth von Franklin, Aaron, Salgueiro, Vivian C., Layton, Abigail J., Sullivan, Rudi, Mize, Todd, Vázquez-Iniesta, Lucía, Benedict, Samuel T., Gurcha, Sudagar S., Anso, Itxaso, Besra, Gurdyal S., Banzhaf, Manuel, Lovering, Andrew L., Williams, Spencer J., Guerin, Marcelo E., Scott, Nichollas E., Prados-Rosales, Rafael, Lowe, Elisabeth C., Moynihan, Patrick J.

Volltext

Production of third generation bio-fuel through thermal cracking process by utilizing Covid-19 plastic wastes von Ramalingam, Senthil, Thamizhvel, R., Sudagar, S., Silambarasan, R.

Volltext

Structure of the priming arabinosyltransferase AftA required for AG biosynthesis of Mycobacterium tuberculosis von Gong, Yicheng, Wei, Chuancun, Wang, Jun, Mu, Nengjiang, Lu, Qinhong, Wu, Chengyao, Yan, Ning, Yang, Huifang, Zhao, Yao, Yang, Xiuna, Gurcha, Sudagar S, Veerapen, Natacha, Batt, Sarah M, Hao, Zhiqiang, Da, Lintai, Besra, Gurdyal S, Rao, Zihe, Zhang, Lu

Volltext

Keto-mycolic acid-dependent pellicle formation confers tolerance to drug-sensitive Mycobacterium tuberculosis von Sambandan, Dhinakaran, Dao, Dee N, Weinrick, Brian C, Vilchèze, Catherine, Gurcha, Sudagar S, Ojha, Anil, Kremer, Laurent, Besra, Gurdyal S, Hatfull, Graham F, Jacobs, Jr, William R

Volltext

A comparative study of different biomass properties by using pyrolysis process von Sudagar, S., Adhisegar, C., Bernadsha, P., Balamurugan, R.

Volltext

Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production von Dao, Dee N, Sweeney, Kari, Hsu, Tsungda, Gurcha, Sudagar S, Nascimento, Ivan P, Roshevsky, Dan, Besra, Gurdyal S, Chan, John, Porcelli, Steven A, Jacobs, William R

Volltext

Identification of KasA as the cellular target of an anti-tubercular scaffold von Abrahams, Katherine A., Chung, Chun-wa, Ghidelli-Disse, Sonja, Rullas, Joaquín, Rebollo-López, María José, Gurcha, Sudagar S., Cox, Jonathan A. G., Mendoza, Alfonso, Jiménez-Navarro, Elena, Martínez-Martínez, María Santos, Neu, Margarete, Shillings, Anthony, Homes, Paul, Argyrou, Argyrides, Casanueva, Ruth, Loman, Nicholas J., Moynihan, Patrick J., Lelièvre, Joël, Selenski, Carolyn, Axtman, Matthew, Kremer, Laurent, Bantscheff, Marcus, Angulo-Barturen, Iñigo, Izquierdo, Mónica Cacho, Cammack, Nicholas C., Drewes, Gerard, Ballell, Lluis, Barros, David, Besra, Gurdyal S., Bates, Robert H.

Volltext

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target von Gurcha, Sudagar S, Usha, Veeraraghavan, Cox, Jonathan A G, Fütterer, Klaus, Abrahams, Katherine A, Bhatt, Apoorva, Alderwick, Luke J, Reynolds, Robert C, Loman, Nicholas J, Nataraj, VijayaShankar, Alemparte, Carlos, Barros, David, Lloyd, Adrian J, Ballell, Lluis, Hobrath, Judith V, Besra, Gurdyal S

Volltext

Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice von Bhatt, Apoorva, Fujiwara, Nagatoshi, Bhatt, Kiranmai, Gurcha, Sudagar S, Kremer, Laurent, Chen, Bing, Chan, John, Porcelli, Steven A, Kobayashi, Kazuo, Besra, Gurdyal S, Jacobs, William R. Jr

Volltext

Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2 von Zhang, Lu, Zhao, Yao, Gao, Ruogu, Li, Jun, Yang, Xiuna, Gao, Yan, Zhao, Wei, Gurcha, Sudagar S., Veerapen, Natacha, Batt, Sarah M., Besra, Kajelle Kaur, Xu, Wenqing, Bi, Lijun, Zhang, Xian’en, Guddat, Luke W., Yang, Haitao, Wang, Quan, Besra, Gurdyal S., Rao, Zihe

Volltext

3‐Ketosteroid 9α‐hydroxylase is an essential factor in the pathogenesis of Mycobacterium tuberculosis von Hu, Yanmin, Van Der Geize, Robert, Besra, Gurdyal S., Gurcha, Sudagar S., Liu, Alexander, Rohde, Manfred, Singh, Mahavir, Coates, Anthony

Volltext

Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis von Gao, Shan, Wu, Fangyu, Gurcha, Sudagar S., Batt, Sarah M., Besra, Gurdyal S., Rao, Zihe, Zhang, Lu

Volltext

Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis von Usha, Veeraraghavan, Hobrath, Judith V, Gurcha, Sudagar S, Reynolds, Robert C, Besra, Gurdyal S

Volltext

Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component von Stoop, Esther J M, Schipper, Tim, Rosendahl Huber, Sietske K, Nezhinsky, Alexander E, Verbeek, Fons J, Gurcha, Sudagar S, Besra, Gurdyal S, Vandenbroucke-Grauls, Christina M J E, Bitter, Wilbert, van der Sar, Astrid M

Volltext

Ppm1-encoded polyprenyl monophosphomannose synthase activity is essential for lipoglycan synthesis and survival in mycobacteria von Rana, Amrita K, Singh, Albel, Gurcha, Sudagar S, Cox, Liam R, Bhatt, Apoorva, Besra, Gurdyal S

Volltext

Role of Phosphatidylinositol Mannosides in the Interaction between Mycobacteria and DC-SIGN von Driessen, Nicole N, Ummels, Roy, Maaskant, Janneke J, Gurcha, Sudagar S, Besra, Gurdyal S, Ainge, Gary D, Larsen, David S, Painter, Gavin F, Vandenbroucke-Grauls, Christina M.J.E, Geurtsen, Jeroen, Appelmelk, Ben J

Volltext