Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: Novel Atherosclerosis Model Induced by High Fat and Cholesterol Diet von Kawaguchi, Hiroaki, Miyoshi, Noriaki, Miura, Naoki, Fujiki, Makoto, Horiuchi, Masahisa, Izumi, Yasukatsu, Miyajima, Hiroaki, Nagata, Ryoichi, Misumi, Kazuhiro, Takeuchi, Toru, Tanimoto, Akihide, Yoshida, Hiroki

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CYP2C76, a Novel Cytochrome P450 in Cynomolgus Monkey, Is a Major CYP2C in Liver, Metabolizing Tolbutamide and Testosterone von Uno, Yasuhiro, Fujino, Hideki, Kito, Go, Kamataki, Tetsuya, Nagata, Ryoichi

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Characterization of cynomolgus monkey cytochrome P450 (CYP) cDNAs: Is CYP2C76 the only monkey-specific CYP gene responsible for species differences in drug metabolism? von Uno, Yasuhiro, Hosaka, Shinya, Matsuno, Kiyomi, Nakamura, Chika, Kito, Go, Kamataki, Tetsuya, Nagata, Ryoichi

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Genetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus Macaques von UNO, Yasuhiro, MATSUSHITA, Akinori, OSADA, Naoki, UEHARA, Shotaro, KOHARA, Sakae, NAGATA, Ryoichi, FUKUZAKI, Koichiro, UTOH, Masahiro, MURAYAMA, Norie, YAMAZAKI, Hiroshi

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Newly identified CYP2C93 is a functional enzyme in rhesus monkey, but not in cynomolgus monkey von Uno, Yasuhiro, Uehara, Shotaro, Kohara, Sakae, Iwasaki, Kazuhide, Nagata, Ryoichi, Fukuzaki, Koichiro, Utoh, Masahiro, Murayama, Norie, Yamazaki, Hiroshi

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Ginsenoside Rb1 Reduces Neurodegeneration in the Peri-infarct Area of a Thromboembolic Stroke Model in Non-human Primates von Yoshikawa, Tetsuya, Akiyoshi, Yuki, Susumu, Teruo, Tokado, Hiroshi, Fukuzaki, Koichiro, Nagata, Ryoichi, Samukawa, Keiichi, Iwao, Hiroshi, Kito, Go

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Expression Profile of Hepatic Genes in Cynomolgus Macaques Bred in Cambodia, China, and Indonesia: Implications for Cytochrome P450 Genes von Ise, Ryota, Nakanishi, Yasuharu, Kohara, Sakae, Yamashita, Hiroyuki, Yoshikawa, Tsuyoshi, Iwasaki, Kazuhide, Nagata, Ryoichi, Fukuzaki, Koichiro, Utoh, Masahiro, Nakamura, Chika, Yamazaki, Hiroshi, Uno, Yasuhiro

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A Null Allele Impairs Function of CYP2C76 Gene in Cynomolgus Monkeys: A Possible Genetic Tool for Generation of a Better Animal Model in Drug Metabolism von UNO, Yasuhiro, SAKURABA, Hiroko, UEHARA, Shotaro, KUMANO, Takayuki, MATSUNO, Kiyomi, NAKAMURA, Chika, KITO, Go, KAMATAKI, Tetsuya, NAGATA, Ryoichi

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A Newly Developed DNA Microarray Is Useful to Assess Induction of Cytochromes P450 in the Cynomolgus Monkey von Ise, Ryota, Uehara, Shotaro, Akiyama, Hideo, Kondo, Satoshi, Iwasaki, Kazuhide, Nagata, Ryoichi, Nobumasa, Hitoshi, Yamazaki, Hiroshi, Uno, Yasuhiro

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Sex-Related Differences in the Expression of mfGSTA2, a Novel GST Identified in Cynomolgus Monkey (Macaca fascicularis) von Uno, Yasuhiro, Ohuchi, Tsukasa, Uehara, Shotaro, Kito, Go, Kamataki, Tetsuya, Nagata, Ryoichi

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Effects of Intra-arterial Urokinase on a Non-human Primate Thromboembolic Stroke Model von Susumu, Teruo, Yoshikawa, Tetsuya, Akiyoshi, Yuki, Nagata, Ryoichi, Fujiwara, Michihiro, Kito, Go

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Experimental thromboembolic stroke in cynomolgus monkey von Kito, Go, Nishimura, Akira, Susumu, Teruo, Nagata, Ryoichi, Kuge, Yuji, Yokota, Chiaki, Minematsu, Kazuo

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Characteristics of troponins as myocardial damage biomarkers in cynomolgus monkeys von Minomo, Hirofumi, Torikai, Yusuke, Furukawa, Tomohiro, Uchino, Hiroshi, Kadokura, Hidetomi, Nakama, Kazuhiro, Maeda, Hiroshi, Kamenosono, Takeshi, Sukamoto, Takayuki, Fukuzaki, Koichiro, Nagata, Ryoichi

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The Effects of Repeated Administration of 7,12-Dimethylbenz[a]anthracene on the Induction of Mammary Carcinomas and Dysplasias in Rats von Hori, Takao, Kawaguchi, Hiroaki, Umekita, Yoshihisa, Nagata, Ryoichi, Yoshida, Hiroki

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Lack of CYP1A1 expression is involved in unresponsiveness of the human hepatoma cell line SK-HEP-1 to dioxin von Shiizaki, Kazuhiro, Ohsako, Seiichiroh, Koyama, Toshie, Nagata, Ryoichi, Yonemoto, Junzo, Tohyama, Chiharu

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Effects of Ropinirole on Various Parkinsonian Models in Mice, Rats, and Cynomolgus Monkeys von Fukuzaki, Koichiro, Kamenosono, Takeshi, Nagata, Ryoichi

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Effects of Neonatally Administered Low-dose Diethylstilbestrol on the Induction of Mammary Carcinomas and Dysplasias Induced by 7,12-Dimethylbenz[a]anthracene in Female Rats von Yoshikawa, Tsuyoshi, Kawaguchi, Hiroaki, Umekita, Yoshihisa, Souda, Masakazu, Gejima, Kentaro, Kawashima, Hideo, Nagata, Ryoichi, Yoshida, Hiroki

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Effects of phosphodiesterase (PDE) inhibitors on human ether-a-go-go related gene (hERG) channel activity von Yunomae, Kiyokazu, Ichisaki, Satoko, Matsuo, Junko, Nagayama, Shinichi, Fukuzaki, Koichiro, Nagata, Ryoichi, Kito, Go

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Evaluation of cardiac function in primates using real-time three-dimensional echocardiography as applications to safety assessment von Tsusaki, Hideshi, Yonamine, Haruno, Tamai, Asako, Shimomoto, Mutsuko, Iwao, Hiroshi, Nagata, Ryoichi, Kito, Go

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Increased Bone Mineral Density in Aged Rats with Spontaneous Mammary Dysplasia von Kawaguchi, Hiroaki, Umekita, Yoshihisa, Souda, Masakazu, Gejima, Kentaro, Kawashima, Hideo, Maeda, Hiroshi, Miyajima, Hiroaki, Nagata, Ryoichi, Yoshida, Hiroki

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