The effects of PEGylation on LNP based mRNA delivery to the eye von Ryals, Renee C., Patel, Siddharth, Acosta, Chris, McKinney, Madison, Pennesi, Mark E., Sahay, Gaurav

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Strategies for non-viral vectors targeting organs beyond the liver von Kim, Jeonghwan, Eygeris, Yulia, Ryals, Renee C., Jozić, Antony, Sahay, Gaurav

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Lipid nanoparticles for delivery of messenger RNA to the back of the eye von Patel, Siddharth, Ryals, Renee C, Weller, Kyle K, Pennesi, Mark E, Sahay, Gaurav

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Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors von Kay, Christine N, Ryals, Renee C, Aslanidi, George V, Min, Seok Hong, Ruan, Qing, Sun, Jingfen, Dyka, Frank M, Kasuga, Daniel, Ayala, Andrea E, Van Vliet, Kim, Agbandje-McKenna, Mavis, Hauswirth, William W, Boye, Sanford L, Boye, Shannon E

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Lipid nanoparticles with PEG-variant surface modifications mediate genome editing in the mouse retina von Gautam, Milan, Jozic, Antony, Su, Grace Li-Na, Herrera-Barrera, Marco, Curtis, Allison, Arrizabalaga, Sebastian, Tschetter, Wayne, Ryals, Renee C., Sahay, Gaurav

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The LCHADD Mouse Model Recapitulates Early-Stage Chorioretinopathy in LCHADD Patients von Babcock, Shannon J, Curtis, Allison G, Gaston, Garen, Elizondo, Gabriela, Gillingham, Melanie B, Ryals, Renee C

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Thiophene-based lipids for mRNA delivery to pulmonary and retinal tissues von Eygeris, Yulia, Gupta, Mohit, Kim, Jeonghwan, Jozic, Antony, Gautam, Milan, Renner, Jonas, Nelson, Dylan, Bloom, Elissa, Tuttle, Adam, Stoddard, Jonathan, Reynaga, Rene, Neuringer, Martha, Lauer, Andreas K, Ryals, Renee C, Sahay, Gaurav

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Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography von Ryals, Renee C, Andrews, Michael D, Datta, Shreya, Coyner, Aaron S, Fischer, Cody M, Wen, Yuquan, Pennesi, Mark E, McGill, Trevor J

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The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9–dependent innate immune responses in the liver von Martino, Ashley T., Suzuki, Masataka, Markusic, David M., Zolotukhin, Irene, Ryals, Renee C., Moghimi, Babak, Ertl, Hildegund C.J., Muruve, Daniel A., Lee, Brendan, Herzog, Roland W.

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Peptide-guided lipid nanoparticles deliver mRNA to the neural retina of rodents and nonhuman primates von Herrera-Barrera, Marco, Ryals, Renee C, Gautam, Milan, Jozic, Antony, Landry, Madeleine, Korzun, Tetiana, Gupta, Mohit, Acosta, Chris, Stoddard, Jonathan, Reynaga, Rene, Tschetter, Wayne, Jacomino, Nick, Taratula, Oleh, Sun, Conroy, Lauer, Andreas K, Neuringer, Martha, Sahay, Gaurav

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Preformed Vesicle Approach to LNP Manufacturing Enhances Retinal mRNA Delivery von Eygeris, Yulia, Henderson, Michael I., Curtis, Allison G., Jozić, Antony, Stoddard, Jonathan, Reynaga, Rene, Chirco, Kathleen R., Su, Grace Li‐Na, Neuringer, Martha, Lauer, Andreas K., Ryals, Renee C., Sahay, Gaurav

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Monomethyl Fumarate Protects the Retina From Light-Induced Retinopathy von Jiang, Dan, Ryals, Renee C, Huang, Samuel J, Weller, Kyle K, Titus, Hope E, Robb, Bryan M, Saad, Firas W, Salam, Ribal A, Hammad, Hytham, Yang, Paul, Marks, Daniel L, Pennesi, Mark E

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Retinal Neuroprotective Effects of Flibanserin, an FDA-Approved Dual Serotonin Receptor Agonist-Antagonist von Coyner, Aaron S, Ryals, Renee C, Ku, Cristy A, Fischer, Cody M, Patel, Rachel C, Datta, Shreya, Yang, Paul, Wen, Yuquan, Hen, René, Pennesi, Mark E

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The Role of ERK1/2 Activation in Sarpogrelate-Mediated Neuroprotection von Ku, Cristy A, Ryals, Renee C, Jiang, Dan, Coyner, Aaron S, Weller, Kyle K, Sinha, Wrik, Robb, Bryan M, Yang, Paul, Pennesi, Mark E

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Natural history of cone disease in the murine model of Leber congenital amaurosis due to CEP290 mutation: determining the timing and expectation of therapy von Boye, Shannon E, Huang, Wei-Chieh, Roman, Alejandro J, Sumaroka, Alexander, Boye, Sanford L, Ryals, Renee C, Olivares, Melani B, Ruan, Qing, Tucker, Budd A, Stone, Edwin M, Swaroop, Anand, Cideciyan, Artur V, Hauswirth, William W, Jacobson, Samuel G

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Spontaneous allelic variant in deafness–blindness gene Ush1g resulting in an expanded phenotype von Vartanian, Vladimir, Krey, Jocelyn F., Chatterjee, Paroma, Curtis, Allison, Six, Makayla, Rice, Sean P. M., Jones, Sherri M., Sampath, Harini, Allen, Charles N., Ryals, Renee C., Lloyd, R. Stephen, Barr‐Gillespie, Peter G.

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An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells von Surendran, Harshini, Soundararajan, Lalitha, Reddy K, Vijay Bhaskar, Subramani, Janavi, Stoddard, Jonathan, Reynaga, Rene, Tschetter, Wayne, Ryals, Renee C., Pal, Rajarshi

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Functional and behavioral restoration of vision by gene therapy in the guanylate cyclase-1 (GC1) knockout mouse von Boye, Shannon E, Boye, Sanford L, Pang, Jijing, Ryals, Renee, Everhart, Drew, Umino, Yumiko, Neeley, Andy W, Besharse, Joseph, Barlow, Robert, Hauswirth, William W

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Sarpogrelate, a 5-HT2A Receptor Antagonist, Protects the Retina From Light-Induced Retinopathy von Tullis, Brandon E, Ryals, Renee C, Coyner, Aaron S, Gale, Michael J, Nicholson, Alex, Ku, Cristy, Regis, Dain, Sinha, Wrik, Datta, Shreya, Wen, Yuquan, Yang, Paul, Pennesi, Mark E

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Gene Therapy to Rescue Retinal Degeneration Caused by Mutations in Rhodopsin von Rossmiller, Brian P., Ryals, Renee C., Lewin, Alfred S.

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