PitViper: a software for comparative meta-analysis and annotation of functional screening data von Meslin, Paul-Arthur, Kelly, Lois M, Benbarche, Salima, Lecourt, Séverine, Lin, Kevin H, Rutter, Justine C, Bassil, Christopher F, Itzykson, Raphael, Wood, Kris C, Puissant, Alexandre, Lobry, Camille

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Induced protein degradation for therapeutics: past, present, and future von Yoon, Hojong, Rutter, Justine C, Li, Yen-Der, Ebert, Benjamin L

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Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers von Nussbaum, Daniel P., Martz, Colin A., Waters, Andrew M., Barrera, Alejandro, Liu, Annie, Rutter, Justine C., Cerda-Smith, Christian G., Stewart, Amy E., Wu, Chao, Cakir, Merve, Levandowski, Cecilia B., Kantrowitz, David E., McCall, Shannon J., Pierobon, Mariaelena, Petricoin, Emanuel F., Joshua Smith, J., Reddy, Timothy E., Der, Channing J., Taatjes, Dylan J., Wood, Kris C.

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Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity von Lin, Kevin H., Xie, Abigail, Rutter, Justine C., Ahn, Yeong-ran, Lloyd-Cowden, Julia M., Nichols, Amanda G., Soderquist, Ryan S., Koves, Timothy R., Muoio, Deborah M., MacIver, Nancie J., Lamba, Jatinder K., Pardee, Timothy S., McCall, Chad M., Rizzieri, David A., Wood, Kris C.

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Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer von Lin, Kevin H., Rutter, Justine C., Xie, Abigail, Pardieu, Bryann, Winn, Emily T., Bello, Reinaldo Dal, Forget, Antoine, Itzykson, Raphael, Ahn, Yeong-Ran, Dai, Ziwei, Sobhan, Raiyan T., Anderson, Gray R., Singleton, Katherine R., Decker, Amy E., Winter, Peter S., Locasale, Jason W., Crawford, Lorin, Puissant, Alexandre, Wood, Kris C.

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UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability von Tsai, Jonathan M, Aguirre, Jacob D, Li, Yen-Der, Brown, Jared, Focht, Vivian, Kater, Lukas, Kempf, Georg, Sandoval, Brittany, Schmitt, Stefan, Rutter, Justine C, Galli, Pius, Sandate, Colby R, Cutler, Jevon A, Zou, Charles, Donovan, Katherine A, Lumpkin, Ryan J, Cavadini, Simone, Park, Paul M C, Sievers, Quinlan, Hatton, Charlie, Ener, Elizabeth, Regalado, Brandon D, Sperling, Micah T, Słabicki, Mikołaj, Kim, Jeonghyeon, Zon, Rebecca, Zhang, Zinan, Miller, Peter G, Belizaire, Roger, Sperling, Adam S, Fischer, Eric S, Irizarry, Rafael, Armstrong, Scott A, Thomä, Nicolas H, Ebert, Benjamin L

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Exploration of the tunability of BRD4 degradation by DCAF16 trans-labelling covalent glues von Hassan, Muhammad Murtaza, Li, Yen-Der, Ma, Michelle W., Teng, Mingxing, Byun, Woong Sub, Puvar, Kedar, Lumpkin, Ryan, Sandoval, Brittany, Rutter, Justine C., Jin, Cyrus Y., Wang, Michelle Y., Xu, Shawn, Schmoker, Anna M., Cheong, Hakyung, Groendyke, Brian J., Qi, Jun, Fischer, Eric S., Ebert, Benjamin L., Gray, Nathanael S.

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FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity von Wieder, Nicolas, Fried, Juliana Coraor, Kim, Choah, Sidhom, Eriene-Heidi, Brown, Matthew R., Marshall, Jamie L., Arevalo, Carlos, Dvela-Levitt, Moran, Kost-Alimova, Maria, Sieber, Jonas, Gabriel, Katlyn R., Pacheco, Julian, Clish, Clary, Abbasi, Hamdah Shafqat, Singh, Shantanu, Rutter, Justine C., Therrien, Martine, Yoon, Haejin, Lai, Zon Weng, Baublis, Aaron, Subramanian, Renuka, Devkota, Ranjan, Small, Jonnell, Sreekanth, Vedagopuram, Han, Myeonghoon, Lim, Donghyun, Carpenter, Anne E., Flannick, Jason, Finucane, Hilary, Haigis, Marcia C., Claussnitzer, Melina, Sheu, Eric, Stevens, Beth, Wagner, Bridget K., Choudhary, Amit, Shaw, Jillian L., Pablo, Juan Lorenzo, Greka, Anna

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Template-assisted covalent modification underlies activity of covalent molecular glues von Li, Yen-Der, Ma, Michelle W., Hassan, Muhammad Murtaza, Hunkeler, Moritz, Teng, Mingxing, Puvar, Kedar, Rutter, Justine C., Lumpkin, Ryan J., Sandoval, Brittany, Jin, Cyrus Y., Schmoker, Anna M., Ficarro, Scott B., Cheong, Hakyung, Metivier, Rebecca J., Wang, Michelle Y., Xu, Shawn, Byun, Woong Sub, Groendyke, Brian J., You, Inchul, Sigua, Logan H., Tavares, Isidoro, Zou, Charles, Tsai, Jonathan M., Park, Paul M. C., Yoon, Hojong, Majewski, Felix C., Sperling, Haniya T., Marto, Jarrod A., Qi, Jun, Nowak, Radosław P., Donovan, Katherine A., Słabicki, Mikołaj, Gray, Nathanael S., Fischer, Eric S., Ebert, Benjamin L.

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Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited von Li, Zhaoqi, Ji, Brian W., Dixit, Purushottam D., Tchourine, Konstantine, Lien, Evan C., Hosios, Aaron M., Abbott, Keene L., Rutter, Justine C., Westermark, Anna M., Gorodetsky, Elizabeth F., Sullivan, Lucas B., Vander Heiden, Matthew G., Vitkup, Dennis

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The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies von Su, Angela, Ling, Frank, Vaganay, Camille, Sodaro, Gaetano, Benaksas, Chaima, Dal Bello, Reinaldo, Forget, Antoine, Pardieu, Bryann, Lin, Kevin H., Rutter, Justine C., Bassil, Christopher F., Fortin, Gael, Pasanisi, Justine, Antony-Debre, Ileana, Alexe, Gabriela, Benoist, Jean-Francois, Pruvost, Alain, Pikman, Yana, Qi, Jun, Schlageter, Marie-Helene, Micol, Jean-Baptiste, Roti, Giovanni, Cluzeau, Thomas, Dombret, Herve, Preudhomme, Claude, Fenouille, Nina, Benajiba, Lina, Golan, Hava M., Stegmaier, Kimberly, Lobry, Camille, Wood, Kris C., Itzykson, Raphael, Puissant, Alexandre

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P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia von Lin, Kevin H, Rutter, Justine C, Xie, Abigail, Killarney, Shane T, Vaganay, Camille, Benaksas, Chaima, Ling, Frank, Sodaro, Gaetano, Meslin, Paul-Arthur, Bassil, Christopher F, Fenouille, Nina, Hoj, Jacob, Washart, Rachel, Ang, Hazel X, Cerda-Smith, Christian, Chaintreuil, Paul, Jacquel, Arnaud, Auberger, Patrick, Forget, Antoine, Itzykson, Raphael, Lu, Min, Lin, Jiaxing, Pierobon, Mariaelena, Sheng, Zhecheng, Li, Xinghai, Chilkoti, Ashutosh, Owzar, Kouros, Rizzieri, David A, Pardee, Timothy S, Benajiba, Lina, Petricoin, Emanuel, Puissant, Alexandre, Wood, Kris C

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Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule von Kelly, Lois M, Rutter, Justine C, Lin, Kevin H, Ling, Frank, Duchmann, Matthieu, Latour, Emmanuelle, Arang, Nadia, Pasquer, Hélène, Ho Nhat, Duong, Charles, Juliette, Killarney, Shane T, Ang, Hazel X, Namor, Federica, Culeux, Cécile, Lombard, Bérangère, Loew, Damarys, Swaney, Danielle L, Krogan, Nevan J, Brunel, Luc, Carretero, Élodie, Verdié, Pascal, Amblard, Muriel, Fodil, Sofiane, Huynh, Tony, Sebert, Marie, Adès, Lionel, Raffoux, Emmanuel, Fenouille, Nina, Itzykson, Raphaël, Lobry, Camille, Benajiba, Lina, Forget, Antoine, Martin, Anthony R, Wood, Kris C, Puissant, Alexandre

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