NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts von Marlein, Christopher R., Zaitseva, Lyubov, Piddock, Rachel E., Robinson, Stephen D., Edwards, Dylan R., Shafat, Manar S., Zhou, Zhigang, Lawes, Matthew, Bowles, Kristian M., Rushworth, Stuart A.

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CD38-Driven Mitochondrial Trafficking Promotes Bioenergetic Plasticity in Multiple Myeloma von Marlein, Christopher R, Piddock, Rachel E, Mistry, Jayna J, Zaitseva, Lyubov, Hellmich, Charlotte, Horton, Rebecca H, Zhou, Zhigang, Auger, Martin J, Bowles, Kristian M, Rushworth, Stuart A

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Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment von Shafat, Manar S., Oellerich, Thomas, Mohr, Sebastian, Robinson, Stephen D., Edwards, Dylan R., Marlein, Christopher R., Piddock, Rachel E., Fenech, Matthew, Zaitseva, Lyubov, Abdul-Aziz, Amina, Turner, Jeremy, Watkins, Johnathan A., Lawes, Matthew, Bowles, Kristian M., Rushworth, Stuart A.

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The bone marrow microenvironment – Home of the leukemic blasts von Shafat, Manar S, Gnaneswaran, Bruno, Bowles, Kristian M, Rushworth, Stuart A

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Free fatty-acid transport via CD36 drives β-oxidation-mediated hematopoietic stem cell response to infection von Mistry, Jayna J., Hellmich, Charlotte, Moore, Jamie A., Jibril, Aisha, Macaulay, Iain, Moreno-Gonzalez, Mar, Di Palma, Federica, Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.

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ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection von Mistry, Jayna J., Marlein, Christopher R., Moore, Jamie A., Hellmich, Charlotte, Wojtowicz, Edyta E., Smith, James G. W., Macaulay, Iain, Sun, Yu, Morfakis, Adam, Patterson, Angela, Horton, Rebecca H., Divekar, Devina, Morris, Christopher J., Haestier, Anna, Di Palma, Federica, Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.

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LC3-associated phagocytosis in bone marrow macrophages suppresses acute myeloid leukemia progression through STING activation von Moore, Jamie A, Mistry, Jayna J, Hellmich, Charlotte, Horton, Rebecca H, Wojtowicz, Edyta E, Jibril, Aisha, Jefferson, Matthew, Wileman, Thomas, Beraza, Naiara, Bowles, Kristian M, Rushworth, Stuart A

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HSC-derived fatty acid oxidation in steady-state and stressed hematopoiesis von Mistry, Jayna J., Bowles, Kristian, Rushworth, Stuart A.

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The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistance von Rushworth, Stuart A., Zaitseva, Lyubov, Murray, Megan Y., Shah, Niraj M., Bowles, Kristian M., MacEwan, David J.

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In Vivo Imaging of Bone Marrow Long-Chain Fatty Acid Uptake von Mistry, Jayna J., Rushworth, Stuart A.

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Mitochondrial oxidative phosphorylation in cutaneous melanoma von Kumar, Prakrit R., Moore, Jamie A., Bowles, Kristian M., Rushworth, Stuart A., Moncrieff, Marc D.

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Identification of Bruton's tyrosine kinase as a therapeutic target in acute myeloid leukemia von Rushworth, Stuart A., Murray, Megan Y., Zaitseva, Lyubov, Bowles, Kristian M., MacEwan, David J.

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HO-1 underlies resistance of AML cells to TNF-induced apoptosis von Rushworth, Stuart A., MacEwan, David J.

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Lipopolysaccharide-Induced Expression of NAD(P)H:Quinone Oxidoreductase 1 and Heme Oxygenase-1 Protects against Excessive Inflammatory Responses in Human Monocytes von Rushworth, Stuart A, MacEwan, David J, O'Connell, Maria A

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Acute myeloid leukemia-driven IL-3-dependent upregulation of BCL2 in non-malignant hematopoietic stem and progenitor cells increases venetoclax-induced cytopenias von Fowler-Shorten, Dominic J, Maynard, Rebecca S, Hampton, Katherine, Altera, Annalisa, Markham, Matthew, Ehikioya, Martha, Wojtowicz, Edyta E, Bowles, Kristian M, Rushworth, Stuart A, Hellmich, Charlotte

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Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment von Abdul-Aziz, Amina M., Sun, Yu, Hellmich, Charlotte, Marlein, Christopher R., Mistry, Jayna, Forde, Eoghan, Piddock, Rachel E., Shafat, Manar S., Morfakis, Adam, Mehta, Tarang, Di Palma, Federica, Macaulay, Iain, Ingham, Christopher J., Haestier, Anna, Collins, Angela, Campisi, Judith, Bowles, Kristian M., Rushworth, Stuart A.

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ARQ531: the therapy that targets multiple pathways in acute myeloid leukemia von Hellmich, Charlotte, Bowles, Kristian, Rushworth, Stuart

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BCL-2 inhibition in haematological malignancies: Clinical application and complications von Fowler-Shorten, Dominic J., Hellmich, Charlotte, Markham, Matthew, Bowles, Kristian M., Rushworth, Stuart A.

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Daratumumab inhibits acute myeloid leukemia metabolic capacity by blocking mitochondrial transfer from mesenchymal stromal cells von Mistry, Jayna J., Moore, Jamie A., Kumar, Prakrit, Marlein, Christopher R., Hellmich, Charlotte, Pillinger, Genevra, Jibril, Aisha, Di Palma, Federica, Collins, Angela, Bowles, Kristian M., Rushworth, Stuart A.

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Acute Myeloid Leukaemia Drives Metabolic Changes in the Bone Marrow Niche von Maynard, Rebecca S., Hellmich, Charlotte, Bowles, Kristian M., Rushworth, Stuart A.

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