A randomized, repeat‐dose, pharmacodynamic and safety study of an antidote‐controlled factor IXa inhibitor von CHAN, M. Y., RUSCONI, C. P., ALEXANDER, J. H., TONKENS, R. M., HARRINGTON, R. A., BECKER, R. C.

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Blocking the Initiation of Coagulation by RNA Aptamers to Factor VIIa von Rusconi, Christopher P., Yeh, Alice, Lyerly, H. Kim, Lawson, Jeffrey H., Sullenger, Bruce A.

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A phase 1 ascending dose study of a subcutaneously administered factor IXa inhibitor and its active control agent von VAVALLE, J. P., RUSCONI, C. P., ZELENKOFSKE, S., WARGIN, W. A., ALEXANDER, J. H., BECKER, R. C.

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A Novel Antidote-Controlled Anticoagulant Reduces Thrombin Generation and Inflammation and Improves Cardiac Function in Cardiopulmonary Bypass Surgery von Nimjee, Shahid M, Keys, J R, Pitoc, G A, Quick, G, Rusconi, C P, Sullenger, Bruce A

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Developing aptamers into therapeutics von White, R R, Sullenger, B A, Rusconi, C P

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Inhibition of Rat Corneal Angiogenesis by a Nuclease-Resistant RNA Aptamer Specific for Angiopoietin-2 von White, Rebekah R., Shan, Siqing, Rusconi, Christopher P., Shetty, Geetha, Dewhirst, Mark W., Kontos, Christopher D., Sullenger, Bruce A.

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RNA aptamers as reversible antagonists of coagulation factor IXa von Rusconi, Christopher P, Sullenger, Bruce A, Scardino, Elizabeth, Layzer, Juliana, Pitoc, George A, Ortel, Thomas L, Monroe, Dougald

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The effect of the REG2 Anticoagulation System on thrombin generation kinetics: a pharmacodynamic and pharmacokinetic first-in-human study von Vavalle, J. P., Rusconi, C. P., Zelenkofske, S., Wargin, W. A., Ortel, T. L., Alexander, J. H., Povsic, T. J., Becker, R. C.

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Dose Selection for a Direct and Selective Factor IXa Inhibitor and its Complementary Reversal Agent: Translating Pharmacokinetic and Pharmacodynamic Properties of the REG1 System t... von Povsic, T. J., Cohen, M. G., Chan, M. Y., Zelenkofske, S. L., Wargin, W. A., Harrington, R. A., Alexander, J. H., Rusconi, C. P., Becker, R. C.

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Mitochondrial import of only one of three nuclear‐encoded glutamine tRNAs in Tetrahymena thermophila von Rusconi, C. P., Cech, T. R.

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Aptamers: an emerging class of therapeutics von Nimjee, Shahid M, Rusconi, Christopher P, Sullenger, Bruce A

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Nucleic acid aptamers as antithrombotic agents: Opportunities in extracellular therapeutics von Becker, Richard, Povsic, Thomas, Cohen, Mauricio G., Rusconi, Christopher, Sullenger, Bruce

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Identification and sequencing of two isopentenyladenosine-modified transfer RNAs from Chinese hamster ovary cells von Warner, Gregory J., Faust, Jerry R., Rusconi, Christopher P., White, Irene E.

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Antidote-mediated control of an anticoagulant aptamer in vivo von Rusconi, Christopher P, Sullenger, Bruce A, Roberts, Joseph D, Pitoc, George A, Nimjee, Shahid M, White, Rebekah R, Quick, George, Scardino, Elizabeth, Fay, William P

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Pegnivacogin results in near complete FIX inhibition in acute coronary syndrome patients: RADAR pharmacokinetic and pharmacodynamic substudy von Povsic, Thomas J., Wargin, William A., Alexander, John H., Krasnow, Joshua, Krolick, Merill, Cohen, Mauricio G., Mehran, Roxana, Buller, Christopher E., Bode, Christoph, Zelenkofske, Steven L., Rusconi, Christopher P., Becker, Richard C.

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The anticodon is the signal sequence for mitochondrial import of glutamine tRNA in Tetrahymena von Rusconi, C P, Cech, T R

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The potential of aptamers as anticoagulants von Nimjee, Shahid M., Rusconi, Christopher P., Harrington, Robert A., Sullenger, Bruce A.

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RNA aptamer to thrombin binds anion-binding exosite-2 and alters protease inhibition by heparin-binding serpins von Jeter, Martha L, Ly, Linda V, Fortenberry, Yolanda M, Whinna, Herbert C, White, Rebekah R, Rusconi, Christopher P, Sullenger, Bruce A, Church, Frank C

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Regulatable aptamers in medicine: focus on antithrombotic strategies von Potti, Anil, Rusconi, Christopher P, Sullenger, Bruce A, Ortel, Thomas L

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Therapeutic Aptamers and Antidotes: A Novel Approach to Safer Drug Design von Sullenger, B. A., White, R. R., Rusconi, C. P.

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