The Transcription Factors T-bet and Eomes Control Key Checkpoints of Natural Killer Cell Maturation von Gordon, Scott M., Chaix, Julie, Rupp, Levi J., Wu, Junmin, Madera, Sharline, Sun, Joseph C., Lindsten, Tullia, Reiner, Steven L.

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Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits von Roybal, Kole T., Rupp, Levi J., Morsut, Leonardo, Walker, Whitney J., McNally, Krista A., Park, Jason S., Lim, Wendell A.

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CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells von Rupp, Levi J., Schumann, Kathrin, Roybal, Kole T., Gate, Rachel E., Ye, Chun J., Lim, Wendell A., Marson, Alexander

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Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors von Roybal, Kole T., Williams, Jasper Z., Morsut, Leonardo, Rupp, Levi J., Kolinko, Isabel, Choe, Joseph H., Walker, Whitney J., McNally, Krista A., Lim, Wendell A.

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Synthetic biology approaches to engineer T cells von Wu, Chia-Yung, Rupp, Levi J, Roybal, Kole T, Lim, Wendell A

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Domain-Specific and Stage-Intrinsic Changes in Tcrb Conformation during Thymocyte Development von Majumder, Kinjal, Rupp, Levi J, Yang-Iott, Katherine S, Koues, Olivia I, Kyle, Katherine E, Bassing, Craig H, Oltz, Eugene M

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The microRNA biogenesis machinery modulates lineage commitment during αβ T cell development von Rupp, Levi J, Brady, Brenna L, Carpenter, Andrea C, De Obaldia, Maria Elena, Bhandoola, Avinash, Bosselut, Remy, Muljo, Stefan A, Bassing, Craig H

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Requirement for dicer in survival of proliferating thymocytes experiencing DNA double-strand breaks von Brady, Brenna L, Rupp, Levi J, Bassing, Craig H

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The microRNA Biogenesis Machinery Modulates Lineage Commitment during alpha beta T Cell Development von Rupp, Levi J, Brady, Brenna L, Carpenter, Andrea C, De Obaldia, Maria Elena, Bhandoola, Avinash, Bosselut, Remy, Muljo, Stefan A, Bassing, Craig H

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Molecular Analysis of Mouse T Cell Receptor α and β Gene Rearrangements von Rupp, Levi J., Chen, Liang, Krangel, Michael S., Bassing, Craig H.

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A unified approach for process-based hydrologic modeling: 1. Modeling concept von Clark, Martyn P., Nijssen, Bart, Lundquist, Jessica D., Kavetski, Dmitri, Rupp, David E., Woods, Ross A., Freer, Jim E., Gutmann, Ethan D., Wood, Andrew W., Brekke, Levi D., Arnold, Jeffrey R., Gochis, David J., Rasmussen, Roy M.

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Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer von Barbieri, Christopher E, Baca, Sylvan C, Lawrence, Michael S, Demichelis, Francesca, Blattner, Mirjam, Theurillat, Jean-Philippe, White, Thomas A, Stojanov, Petar, Van Allen, Eliezer, Stransky, Nicolas, Nickerson, Elizabeth, Chae, Sung-Suk, Boysen, Gunther, Auclair, Daniel, Onofrio, Robert C, Park, Kyung, Kitabayashi, Naoki, MacDonald, Theresa Y, Sheikh, Karen, Vuong, Terry, Guiducci, Candace, Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L, Saksena, Gordon, Voet, Douglas, Hussain, Wasay M, Ramos, Alex H, Winckler, Wendy, Redman, Michelle C, Ardlie, Kristin, Tewari, Ashutosh K, Mosquera, Juan Miguel, Rupp, Niels, Wild, Peter J, Moch, Holger, Morrissey, Colm, Nelson, Peter S, Kantoff, Philip W, Gabriel, Stacey B, Golub, Todd R, Meyerson, Matthew, Lander, Eric S, Getz, Gad, Rubin, Mark A, Garraway, Levi A

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The heads of the measles virus attachment protein move to transmit the fusion-triggering signal von Cattaneo, Roberto, Navaratnarajah, Chanakha K, Oezguen, Numan, Rupp, Levi, Kay, Leah, Leonard, Vincent H J, Braun, Werner

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259 Discovery of synthetic signaling pathway receptors that increase the potency of CAR-T cells through optimized STAT activity von Gardner, Thomas J, Millare, Beatriz, Yao, Anzhi, Chen, Lan, Cass, Ashley, Mohanty, Suchismita, Chen, Jeremy, Gomez, Alma, DeTomaso, David, Ku, Manching, Berthoin, Lionel, Lim, Meng, Ong, Azalea, Thomas, Vince, Quant, Nicholas, Hsu, Brian, Casbon, Amy-Jo, Bezman, Natalie, Cooper, Aaron, Gray-Rupp, Levi, Boroughs, Angela, Nicholas Haining, W

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Abstract 4073: Tunable STAT activation by synthetic pathway activators (SPAs) increases engineered T-cell potency and persistence von Gardner, Thomas J., Millare, Beatriz, Yao, Anzhi, Cass, Ashley, Mohanty, Suchismita, Chen, Jeremy, Gomez, Alma, DeTomaso, David, Ku, Manching, Berthoin, Lionel, Lim, Meng, Ong, Azalea, Thomas, Vince, Quant, Nicholas, Hsu, Brian, Casbon, Amy-Jo, Bezman, Natalie, Cooper, Aaron, Gray-Rupp, Levi, Boroughs, Angela C., Haining, W. Nicholas

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Abstract 1768: Multiplexed shRNA cassettes targeting orthogonal pathways (FAS/PTPN2/TGFBR) enhance the potency of integrated circuit T cells (ICTs) in multiple solid tumor models von Gardner, Thomas J., Litterman, Adam, Singh, Brenal K., Silva, Luisa, Hari, Mukund, Zhou, Stanley, Tang, Colin, Joshi, Sahil, Gagnon, John, Takacsi-Nagy, Oliver, Hall, Jason, Pope, Hans, Zhang, James, Gomez, Alma, Chen, Jeremy, Mohanty, Suchismita, Thomas, Vince, Quant, Nicholas, Millare, Beatriz, Casbon, Amy-Jo, Bezman, Natalie, Gray-Rupp, Levi, Boroughs, Angela C., Haining, W. Nicholas

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Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer von Mittmann, Gesa, Laiouar-Pedari, Sara, Mehrtens, Hendrik A, Haggenmüller, Sarah, Bucher, Tabea-Clara, Chanda, Tirtha, Gaisa, Nadine T, Wagner, Mathias, Klamminger, Gilbert Georg, Rau, Tilman T, Neppl, Christina, Compérat, Eva Maria, Gocht, Andreas, Hämmerle, Monika, Rupp, Niels J, Westhoff, Jula, Krücken, Irene, Seidl, Maximillian, Schürch, Christian M, Bauer, Marcus, Solass, Wiebke, Tam, Yu Chun, Weber, Florian, Grobholz, Rainer, Augustyniak, Jaroslaw, Kalinski, Thomas, Hörner, Christian, Mertz, Kirsten D, Döring, Constanze, Erbersdobler, Andreas, Deubler, Gabriele, Bremmer, Felix, Sommer, Ulrich, Brodhun, Michael, Griffin, Jon, Lenon, Maria Sarah L, Trpkov, Kiril, Cheng, Liang, Chen, Fei, Levi, Angelique, Cai, Guoping, Nguyen, Tri Q, Amin, Ali, Cimadamore, Alessia, Shabaik, Ahmed, Manucha, Varsha, Ahmad, Nazeel, Messias, Nidia, Sanguedolce, Francesca, Taheri, Diana, Baraban, Ezra, Jia, Liwei, Shah, Rajal B, Siadat, Farshid, Swarbrick, Nicole, Park, Kyung, Hassan, Oudai, Sakhaie, Siamak, Downes, Michelle R, Miyamoto, Hiroshi, Williamson, Sean R, Holland-Letz, Tim, Schneider, Carolin V, Kather, Jakob Nikolas, Tolkach, Yuri, Brinker, Titus J

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Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer von Mittmann, Gesa, Laiouar-Pedari, Sara, Mehrtens, Hendrik A, Haggenmüller, Sarah, Bucher, Tabea-Clara, Chanda, Tirtha, Gaisa, Nadine T, Wagner, Mathias, Gilbert, Georg Klamminger, Rau, Tilman T, Neppl, Christina, Compérat, Eva Maria, Gocht, Andreas, Hämmerle, Monika, Rupp, Niels J, Westhoff, Jula, Krücken, Irene, Seidl, Maximillian, Schürch, Christian M, Bauer, Marcus, Solass, Wiebke, Tam, Yu Chun, Weber, Florian, Grobholz, Rainer, Augustyniak, Jaroslaw, Kalinski, Thomas, Hörner, Christian, Mertz, Kirsten D, Döring, Constanze, Erbersdobler, Andreas, Deubler, Gabriele, Bremmer, Felix, Sommer, Ulrich, Brodhun, Michael, Griffin, Jon, Lenon, Maria Sarah L, Trpkov, Kiril, Cheng, Liang, Chen, Fei, Levi, Angelique, Cai, Guoping, Nguyen, Tri Q, Amin, Ali, Cimadamore, Alessia, Shabaik, Ahmed, Manucha, Varsha, Ahmad, Nazeel, Messias, Nidia, Sanguedolce, Francesca, Taheri, Diana, Baraban, Ezra, Jia, Liwei, Shah, Rajal B, Siadat, Farshid, Swarbrick, Nicole, Park, Kyung, Oudai Hassan, Sakhaie, Siamak, Downes, Michelle R, Miyamoto, Hiroshi, Williamson, Sean R, Holland-Letz, Tim, Schneider, Carolin V, Kather, Jakob Nikolas, Tolkach, Yuri, Brinker, Titus J

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Immune cells having co-expressed TGFBR SHRNAs von GAGNON, JOHN, SINGH, BRENAL, GRAY-RUPP, LEVI, COOPER, AARON, HALL, JASON, BEZMAN, NATALIE, CASBON, AMY-JO, LITTERMAN, ADAM

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