Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy von Roongta, Urvashi V, Pabalan, Jonathan G, Wang, Xinyu, Ryseck, Rolf-Peter, Fargnoli, Joseph, Henley, Benjamin J, Yang, Wen-Pin, Zhu, Jun, Madireddi, Malavi T, Lawrence, R Michael, Wong, Tai W, Rupnow, Brent A

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Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors von Richters, André, Doyle, Shelby K., Freeman, David B., Lee, Christina, Leifer, Becky S., Jagannathan, Sajjeev, Kabinger, Florian, Koren, Jošt Vrabič, Struntz, Nicholas B., Urgiles, Julie, Stagg, Ryan A., Curtin, Brice H., Chatterjee, Deep, Mathea, Sebastian, Mikochik, Peter J., Hopkins, Tamara D., Gao, Hua, Branch, Jonathan R., Xin, Hong, Westover, Lori, Bignan, Gilles C., Rupnow, Brent A., Karlin, Kristen L., Olson, Calla M., Westbrook, Thomas F., Vacca, Joseph, Wilfong, Chris M., Trotter, B. Wesley, Saffran, Douglas C., Bischofberger, Norbert, Knapp, Stefan, Russo, Joshua W., Hickson, Ian, Bischoff, James R., Gottardis, Marco M., Balk, Steven P., Lin, Charles Y., Pop, Marius S., Koehler, Angela N.

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AKR1C3 mediates pan‐AR antagonist resistance in castration‐resistant prostate cancer von Hertzog, Jennifer R., Zhang, Zhuming, Bignan, Gilles, Connolly, Peter J., Heindl, Jason E., Janetopoulos, Christopher J., Rupnow, Brent A., McDevitt, Theresa M.

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Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor von CARBONI, Joan M, LEE, Adrian V, HURLBURT, Warren, AIXIN LI, SAUJNIER, Mark, VELAPARTHI, Upender, WANG, Cindy, WEN, Mei-Li, WESTHOUSE, Richard A, WINMAN, Mark, ZIMMERMANN, Kurt, RUPNOW, Brent A, HADSELL, Darryl L, WONG, Tai W, ROWLEY, Bruce R, LEE, Francis Y, BOL, David K, CAMUSO, Amy E, GOTTARDIS, Marco, GREER, Ann F, CHING PING HO

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Direct evidence that apoptosis enhances tumor responses to fractionated radiotherapy von RUPNOW, B. A, MURTHA, A. D, ALARCON, R. M, GIACCIA, A. J, KNOX, S. J

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Long-term follow-up of patients with Stage III follicular lymphoma treated with primary radiotherapy at Stanford University von Murtha, Albert D, Knox, Susan J, Hoppe, Richard T, Rupnow, Brent A, Hanson, John

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Modulation of c-myc activity and apoptosis in vivo von ALARCON, R. M, RUPNOW, B. A, GRAEBER, T. G, KNOX, S. J, GIACCIA, A. J

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Synthetic Lethality of Retinoblastoma Mutant Cells in the Drosophila Eye by Mutation of a Novel Peptidyl Prolyl Isomerase Gene von Edgar, Kyle A, Belvin, Marcia, Parks, Annette L, Whittaker, Kellie, Mahoney, Matt B, Nicoll, Monique, Park, Christopher C, Winter, Christopher G, Chen, Feng, Lickteig, Kim, Ahmad, Ferhad, Esengil, Hanife, Lorenzi, Matthew V, Norton, Amanda, Rupnow, Brent A, Shayesteh, Laleh, Tabios, Mariano, Young, Lynn M, Carroll, Pamela M, Kopczynski, Casey, Plowman, Gregory D, Friedman, Lori S, Francis-Lang, Helen L

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CheckMate 331: An open-label, randomized phase III trial of nivolumab versus chemotherapy in patients (pts) with relapsed small cell lung cancer (SCLC) after first-line platinum-ba... von Horn, Leora, Reck, Martin, Gettinger, Scott N., Spigel, David R., Antonia, Scott Joseph, Rupnow, Brent A., Pieters, Anne, Selvaggi, Giovanni, Fairchild, Justin P., Peters, Solange

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p53 mediates apoptosis induced by c-Myc activation in hypoxic or gamma irradiated fibroblasts von Rupnow, B A, Alarcon, R M, Giaccia, A J, Knox, S J

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Abstract LB087: Characterization of JNJ-70218902, a TMEFF2 x CD3 bispecific antibody, in prostate cancer models von Basu, Subhasree, Russell, Mike, Sproesser, Katrin, Mattson, Bethany, Lowenstein, Cassandra L., Venkataramani, Sathya, Diamond, Maura, Ernst, Robin E., Jarantow, Stephen, Wong, Jackson, Chu, Gerald, Packman, Kathryn, Tian, Shaozhou Ken, Brodeur, Scott R., Yu, Margaret, Rupnow, Brent A.

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Abstract 5395: Anti-tumor activity of BMS-595, a novel CK2 kinase inhibitor von Rupnow, Brent A., Yu, Chiang, Pabalan, Jonathan G., Roongta, Urvashi V., Lippy, Jonathan S., Dongre, Ashok R., Obermeier, Mary T., Fura, Aberra, Elzinga, Paul A., Henley, Benjamin J., Fargnoli, Joseph, Lee, Francis Y., Foster, William R., Tarby, Christine M., Fink, Brian E., Tokarski, John S., Gavai, Ashvinikumar V., Wong, Tai W., Hunt, John T., Vite, Gregory D., Purandare, Ashok V.

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Abstract 5417: The identification of BMS-595, an orally active imidazo[1,2-b]pyridazine CK2 inhibitor with in vivo anti-tumor activity von Tarby, Christine M., He, Liqi, Fink, Brian E., Nation, Andrew, Zhao, Yufen, Kim, Soong-Hoon, Chen, Libing, Tokarski, John S., Yu, Chiang, Pabalan, Jonathan G., Roongta, Urvashi V., Lippy, Jonathan, Obermeier, Mary, Elzinga, Paul A., Fura, Aberra, Henley, Benjamin, Fargnoli, Joseph J., Foster, William R., Gavai, Ashvinikumar V., Wong, Tai W., Hunt, John T., Vite, Gregory D., Purandare, Ashok V., Rupnow, Brent A.

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Myc activation reduces fibroblast clonogenicity via an apoptotic mechanism that can be suppressed by a soluble paracrine factor von Rupnow, Brent A, Murtha 1, Albert D, Chen, Eric, Knox, Susan J

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Abstract 4115: Depletion of unsaturated fatty acids by stearoyl-coA desaturase inhibition results in endoplasmic reticulum stress-mediated tumor cell death von Roongta, Urvashi V., Pabalan, Jonathan G., Wang, Cindy, Ryseck, Rolf-Peter, Fargnoli, Joseph, Henley, Benjamin, Yang, Wen-Pin, Zhu, Jun, Madireddi, Malavi, Lawrence, Michael, Wong, Tai W., Rupnow, Brent A.

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Abstract C62: Cancer cell dependence on unsaturated fatty acids implicates stearoyl-coA desaturase as a target for cancer therapy von Roongta, Urvashi V., Lawrence, R. Michael, Wong, Tai W., Rupnow, Brent A., Pabalan, Jonathan G., Wang, Xinyu, Ryseck, Rolf-Peter, Fargnoli, Joseph, Henley, Benjamin J., Yang, Wen-Pin, Zhu, Jun, Madireddi, Malavi T.

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Association of BCL-2 with membrane hyperpolarization and radioresistance von Gilbert, Mark S., Saad, Ali H., Rupnow, Brent A., Knox, Susan J.

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COMBINATION OF CK2 INHIBITORS AND IMMUNE CHECKPOINT MODULATORS FOR CANCER TREATMENT von JURE-KUNKEL, Maria, RUPNOW, Brent, A

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89 Apoptotic potential and cell sensitivity to fractionated radiotherapy von Rupnow, Brent A., Murtha, Albert D., Alarcon, Rodolfo M., Giaccia, Amato J., Knox, Susan J.

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BIOMARKERS OF CYCLIN-DEPENDENT KINASE MODULATION von WEBSTER, KEVIN, R, WONG, TAI, W, RUPNOW, BRENT, A, LI, MARTHA, JACKSON, DONALD, G

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