A bioluminescence reporter mouse model for visualizing and quantifying CD8+ T cells in vivo von Bettano, Kimberly, Zielstorff, Mark, Sevilla, Raquel, Yang, Ruojing, Zhou, Heather, Rosahl, Thomas, Zhang-Hoover, Jie, Moy, Lily Y., Zhang, Weisheng

Volltext

Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications von Lim, Jongwon, Altman, Michael D., Baker, James, Brubaker, Jason D., Chen, Hongmin, Chen, Yiping, Kleinschek, Melanie A., Li, Chaomin, Liu, Duan, Maclean, John K.F., Mulrooney, Erin F., Presland, Jeremy, Rakhilina, Larissa, Smith, Graham F., Yang, Ruojing

Volltext

Discovery of Potent, Selective, Orally Bioavailable Stearoyl-CoA Desaturase 1 Inhibitors von Liu, Gang, Lynch, John K, Freeman, Jennifer, Liu, Bo, Xin, Zhili, Zhao, Hongyu, Serby, Michael D, Kym, Philip R, Suhar, Tom S, Smith, Harriet T, Cao, Ning, Yang, Ruojing, Janis, Rich S, Krauser, Joel A, Cepa, Steven P, Beno, David W. A, Sham, Hing L, Collins, Christine A, Surowy, Teresa K, Camp, Heidi S

Volltext

Glucose Limitation Induces GCN4 Translation by Activation of Gcn2 Protein Kinase von Yang, Ruojing, Wek, Sheree A., Wek, Ronald C.

Volltext

cSSMD: assessing collective activity for addressing off-target effects in genome-scale RNA interference screens von Zhang, Xiaohua Douglas, Santini, Francesca, Lacson, Raul, Marine, Shane D., Wu, Qian, Benetti, Luca, Yang, Ruojing, McCampbell, Alex, Berger, Joel P., Toolan, Dawn M., Stec, Erica M., Holder, Daniel J., Soper, Keith A., Heyse, Joseph F., Ferrer, Marc

Volltext

A genome-wide siRNA screen to identify modulators of insulin sensitivity and gluconeogenesis von Yang, Ruojing, Lacson, Raul G, Castriota, Gino, Zhang, Xiaohua D, Liu, Yaping, Zhao, Wenqing, Einstein, Monica, Camargo, Luiz Miguel, Qureshi, Sajjad, Wong, Kenny K, Zhang, Bei B, Ferrer, Marc, Berger, Joel P

Volltext

Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor von Ma, Xiaoshen, Sloman, David L., Duggal, Ruchia, Anderson, Kenneth D., Ballard, Jeanine E., Bharathan, Indu, Brynczka, Christopher, Gathiaka, Symon, Henderson, Timothy J., Lyons, Thomas W., Miller, Richard, Munsell, Erik V., Orth, Peter, Otte, Ryan D., Palani, Anandan, Rankic, Danica A., Robinson, Michelle R., Sather, Aaron C., Solban, Nicolas, Song, Xuelei Sherry, Wen, Xin, Xu, Zangwei, Yang, Yi, Yang, Ruojing, Day, Phil J., Stoeck, Alexander, Bennett, David Jonathan, Han, Yongxin

Volltext

Hepatic Expression of a Targeting Subunit of Protein Phosphatase-1 in Streptozotocin-diabetic Rats Reverses Hyperglycemia and Hyperphagia Despite Depressed Glucokinase Expression von Yang, Ruojing, Newgard, Christopher B

Volltext

Determination of EPAC2 function using EPAC2 null Min6 sublines generated through CRISPR-Cas9 technology von Xu, Haiyan, Yang, Yi, Chen, Yiping, Mueller, Uwe, Iyer, Sharanya, Presland, Jeremy, Yang, Ruojing, Kariv, Ilona

Volltext

Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRAS G12C Inhibitor von Ma, Xiaoshen, Sloman, David L, Duggal, Ruchia, Anderson, Kenneth D, Ballard, Jeanine E, Bharathan, Indu, Brynczka, Christopher, Gathiaka, Symon, Henderson, Timothy J, Lyons, Thomas W, Miller, Richard, Munsell, Erik V, Orth, Peter, Otte, Ryan D, Palani, Anandan, Rankic, Danica A, Robinson, Michelle R, Sather, Aaron C, Solban, Nicolas, Song, Xuelei Sherry, Wen, Xin, Xu, Zangwei, Yang, Yi, Yang, Ruojing, Day, Phil J, Stoeck, Alexander, Bennett, David Jonathan, Han, Yongxin

Volltext

Hyperlipidemic Effects of Dietary Saturated Fats Mediated through PGC-1β Coactivation of SREBP von Lin, Jiandie, Yang, Ruojing, Tarr, Paul T., Wu, Pei-Hsuan, Handschin, Christoph, Li, Siming, Yang, Wenli, Pei, Liming, Uldry, Marc, Tontonoz, Peter, Newgard, Christopher B., Spiegelman, Bruce M.

Volltext

c-Jun N-terminal kinase pathways in diabetes von Yang, Ruojing, Trevillyan, James M.

Volltext

Bioenergetic Analysis of Peroxisome Proliferator-activated Receptor γ Coactivators 1α and 1β (PGC-1α and PGC-1β) in Muscle Cells von St-Pierre, Julie, Lin, Jiandie, Krauss, Stefan, Tarr, Paul T., Yang, Ruojing, Newgard, Christopher B., Spiegelman, Bruce M.

Volltext

Glycogen-targeting Subunits and Glucokinase Differentially Affect Pathways of Glycogen Metabolism and Their Regulation in Hepatocytes von Yang, Ruojing, Cao, Liwei, Gasa, Rosa, Brady, Matthew J, Sherry, A Dean, Newgard, Christopher B

Volltext

Abstract B074: Discovery of MK-1084, a low dose selective clinical stage KRAS G12C inhibitor von Maddess, Matthew L, Sloman, David L, Ma, Xiaoshen, Palani, Anandan, Stoeck, Alexander, Sather, Aaron C, Solban, Nicolas, Duggal, Ruchia, Ballard, Jeanine, Munsell, Erik V, Chen, Lin-Chi, Han, Yongxin, Miller, Richard, Gathiaka, Symon, Brynczka, Christopher, Li, Hongming, Yang, Ruojing, Brynczka, Christopher, Day, Phil

Volltext

Establishing and Validating Cellular Functional Target Engagement Assay for Selective IRAK4 Inhibitor Discovery von Chen, Yiping, Sun, Dongyu, Yang, Ruojing, Lim, Jongwon, Sondey, Christopher, Presland, Jeremy, Rakhilina, Larissa, Addona, George, Kariv, Ilona, Chen, Hongmin

Volltext

Reversal of Diet-induced Glucose Intolerance by Hepatic Expression of a Variant Glycogen-targeting Subunit of Protein Phosphatase-1 von Gasa, Rosa, Clark, Catherine, Yang, Ruojing, DePaoli-Roach, Anna A, Newgard, Christopher B

Volltext

Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation von Smith, Graham F., Altman, Michael D., Andresen, Brian, Baker, James, Brubaker, Jason D., Chen, Hongmin, Chen, Yiping, Childers, Matthew, Donofrio, Anthony, Ferguson, Heidi, Fischer, Christian, Fischmann, Thierry O., Gibeau, Craig, Hicks, Alexander, Jin, Sue, Kattar, Sam, Kleinschek, Melanie A., Leccese, Erica, Lesburg, Charles, Li, Chaomin, Lim, Jongwon, Liu, Duan, Maclean, John K.F., Mansoor, Faruk, Moy, Lilly Y., Mulrooney, Erin F., Necheva, Antoaneta S., Presland, Jeremy, Rakhilina, Larissa, Yang, Ruojing, Torres, Luis, Zhang-Hoover, Jie, Northrup, Alan

Volltext

Optimizing the Real Estate Portfolio Decision Model Based on Modern Portfolio Theory von Ruojing Yang

Volltext bestellen

PGC-1β in the Regulation of Hepatic Glucose and Energy Metabolism von Lin, Jiandie, Tarr, Paul T., Yang, Ruojing, Rhee, James, Puigserver, Pere, Newgard, Christopher B., Spiegelman, Bruce M.

Volltext