Combination of MIDGE-Th1 DNA vaccines with the cationic lipid SAINT-18: Studies on formulation, biodistribution and vector clearance von Endmann, Anne, Oswald, Detlef, Riede, Oliver, Talman, Eduard G, Vos, Roelien E, Schroff, Matthias, Kleuss, Christiane, Ruiters, Marcel H.J, Juhls, Christiane

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Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner von Cano-Rodriguez, David, Gjaltema, Rutger A F., Jilderda, Laura J, Jellema, Pytrick, Dokter-Fokkens, Jelleke, Ruiters, Marcel H J., Rots, Marianne G

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Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter von Chen, Hui, Kazemier, Hinke G, de Groote, Marloes L, Ruiters, Marcel H J, Xu, Guo-Liang, Rots, Marianne G

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Experimental mitochondria-targeted DNA methylation identifies GpC methylation, not CpG methylation, as potential regulator of mitochondrial gene expression von van der Wijst, Monique G. P., van Tilburg, Amanda Y., Ruiters, Marcel H. J., Rots, Marianne G.

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EpCAM in carcinogenesis: the good, the bad or the ugly von van der Gun, Bernardina T.F., Melchers, Lieuwe J., Ruiters, Marcel H.J., de Leij, Lou F.M.H., McLaughlin, Pamela M.J., Rots, Marianne G.

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Targeting Rapamycin to Podocytes Using a Vascular Cell Adhesion Molecule-1 (VCAM-1)-Harnessed SAINT-Based Lipid Carrier System von Visweswaran, Ganesh Ram R, Gholizadeh, Shima, Ruiters, Marcel H J, Molema, Grietje, Kok, Robbert J, Kamps, Jan A A M

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Detection of micrometastatic breast cancer by means of real time quantitative RT‐PCR and immunostaining in perioperative blood samples and sentinel nodes von Schröder, Carolien P., Ruiters, Marcel H.J., de Jong, Steven, Tiebosch, Anton T.M.G., Wesseling, Jelle, Veenstra, Rense, de Vries, Jaap, Hoekstra, Harold J, de Leij, Lou F.M.H., de Vries, Elisabeth G.E.

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Endothelium-targeted delivery of dexamethasone by anti-VCAM-1 SAINT-O-Somes in mouse endotoxemia von Li, Ranran, Kowalski, Piotr S, Morselt, Henriëtte W M, Schepel, Ilona, Jongman, Rianne M, Aslan, Adnan, Ruiters, Marcel H J, Zijlstra, Jan G, Molema, Grietje, van Meurs, Matijs, Kamps, Jan A A M

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The Mitochondrial Epigenome: An Unexplored Avenue to Explain Unexplained Myopathies? von Mposhi, Archibold, Liang, Lin, Mennega, Kevin P, Yildiz, Dilemin, Kampert, Crista, Hof, Ingrid H, Jellema, Pytrick G, de Koning, Tom J, Faber, Klaas Nico, Ruiters, Marcel H J, Niezen-Koning, Klary E, Rots, Marianne G

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Anti-VCAM-1 SAINT-O-Somes enable endothelial-specific delivery of siRNA and downregulation of inflammatory genes in activated endothelium in vivo von Kowalski, Piotr S., Zwiers, Peter J., Morselt, Henriëtte W.M., Kuldo, Joanna M., Leus, Niek G.J., Ruiters, Marcel H.J., Molema, Grietje, Kamps, Jan A.A.M.

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Efficient nontoxic delivery of PD-L1 and PD-L2 siRNA into dendritic cell vaccines using the cationic lipid SAINT-18 von Roeven, Mieke W H, Hobo, Willemijn, van der Voort, Robbert, Fredrix, Hanny, Norde, Wieger J, Teijgeler, Kasper, Ruiters, Marcel H J, Schaap, Nicolaas, Dolstra, Harry

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Regulation of spontaneous and TNF/IFN‐induced IL‐6 expression in two human ovarian‐carcinoma cell lines von Asschert, Johanna G.W., Vellenga, Edo, Ruiters, Marcel H.J., de Vries, Elisabeth G.E.

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Anti-VCAM‑1 and Anti-E-selectin SAINT-O-Somes for Selective Delivery of siRNA into Inflammation-Activated Primary Endothelial Cells von Kowalski, Piotr S, Lintermans, Lucas L, Morselt, Henriëtte W. M, Leus, Niek G. J, Ruiters, Marcel H. J, Molema, Grietje, Kamps, Jan A. A. M

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Cationic lipid-formulated DNA vaccine against hepatitis B virus: immunogenicity of MIDGE-Th1 vectors encoding small and large surface antigen in comparison to a licensed protein va... von Endmann, Anne, Klünder, Katharina, Kapp, Kerstin, Riede, Oliver, Oswald, Detlef, Talman, Eduard G, Schroff, Matthias, Kleuss, Christiane, Ruiters, Marcel H J, Juhls, Christiane

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Effective siRNA delivery to inflamed primary vascular endothelial cells by anti-E-selectin and anti-VCAM-1 PEGylated SAINT-based lipoplexes von Leus, Niek G.J., Talman, Eduard G., Ramana, Pranov, Kowalski, Piotr S., Woudenberg-Vrenken, Titia E., Ruiters, Marcel H.J., Molema, Grietje, Kamps, Jan A.A.M.

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VCAM-1 specific PEGylated SAINT-based lipoplexes deliver siRNA to activated endothelium in vivo but do not attenuate target gene expression von Leus, Niek G.J., Morselt, Henriëtte W.M., Zwiers, Peter J., Kowalski, Piotr S., Ruiters, Marcel H.J., Molema, Grietje, Kamps, Jan A.A.M.

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TCTN2: a novel tumor marker with oncogenic properties von Cano-Rodriguez, David, Campagnoli, Susanna, Grandi, Alberto, Parri, Matteo, Camilli, Elisa De, Song, Chaojun, Jin, Boquan, Lacombe, Aurelien, Pierleoni, Andrea, Bombaci, Mauro, Cordiglieri, Chiara, Ruiters, Marcel Hj, Viale, Giuseppe, Terracciano, Luigi, Sarmientos, Paolo, Abrignani, Sergio, Grandi, Guido, Pileri, Piero, Rots, Marianne G, Grifantini, Renata

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SAINT-liposome-polycation particles, a new carrier for improved delivery of siRNAs to inflamed endothelial cells von Kowalski, Piotr S., Kuninty, Praneeth R., Bijlsma, Klaas T., Stuart, Marc C.A., Leus, Niek G.J., Ruiters, Marcel H.J., Molema, Grietje, Kamps, Jan A.A.M.

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Targeted transfection increases siRNA uptake and gene silencing of primary endothelial cells in vitro — A quantitative study von Ásgeirsdóttir, Sigridur A., Talman, Eduard G., de Graaf, Inge A., Kamps, Jan A.A.M., Satchell, Simon C., Mathieson, Peter W., Ruiters, Marcel H.J., Molema, Grietje

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Targeted SAINT-O-Somes for improved intracellular delivery of siRNA and cytotoxic drugs into endothelial cells von Adrian, Joanna E., Morselt, Henriëtte W.M., Süss, Regine, Barnert, Sabine, Kok, Jan Willem, Ásgeirsdóttir, Sigridur A., Ruiters, Marcel H.J., Molema, Grietje, Kamps, Jan A.A.M.

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