Therapeutics targeting Bcl-2 in hematological malignancies von Ruefli-Brasse, Astrid, Reed, John C

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Apoptosis: A Link between Cancer Genetics and Chemotherapy von Johnstone, Ricky W., Ruefli, Astrid A., Lowe, Scott W.

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STK33 Kinase Activity Is Nonessential in KRAS-Dependent Cancer Cells von BABIJ, Carol, YIHONG ZHANG, FAJARDO, Flordeliza, JACKSON, Angela, ZONDLO, James, YU SUN, ELLISON, Aaron R, PLEWA, Cherylene A, SAN MIGUEL, Tisha, ROBINSON, John, MCCARTER, John, SCHWANDNER, Ralf, KURZEJA, Robert J, JUDD, Ted, CARNAHAN, Josette, DUSSAULT, Isabelle, MUNZLI, Anke, SHEHABELDIN, Amro, FERNANDO, Manory, QUON, Kim, KASSNER, Paul D, RUEFLI-BRASSE, Astrid A, WATSON, Vivienne J

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Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodies von Nolan-Stevaux, Olivier, Zhong, Wendy, Culp, Stacey, Shaffer, Kathy, Hoover, Joseph, Wickramasinghe, Dineli, Ruefli-Brasse, Astrid

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Histone deacetylase inhibitors specifically kill nonproliferating tumour cells von Burgess, Andrew, Ruefli, Astrid, Beamish, Heather, Warrener, Robyn, Saunders, Nicholas, Johnstone, Ricky, Gabrielli, Brian

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Novel mechanisms of apoptosis induced by histone deacetylase inhibitors von PEART, Melissa J, TAINTON, Kellie M, RUEFLI, Astrid A, DEAR, Anthony E, SEDELIES, Karin A, O'REILLY, Lorraine A, WATERHOUSE, Nigel J, TRAPANI, Joseph A, JOHNSTONE, Ricky W

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Multiple physiological functions for multidrug transporter P-glycoprotein? von Johnstone, Ricky W, Ruefli, Astrid A, Smyth, Mark J

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The Histone Deacetylase Inhibitor and Chemotherapeutic Agent Suberoylanilide Hydroxamic Acid (SAHA) Induces a Cell-Death Pathway Characterized by Cleavage of Bid and Production of... von Ruefli, Astrid A., Ausserlechner, Michael J., Bernhard, David, Sutton, Vivien R., Tainton, Kellie M., Kofler, Reinhard, Smyth, Mark J., Johnstone, Ricky W.

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Sphingosine kinase activity is not required for tumor cell viability von Rex, Karen, Jeffries, Shawn, Brown, Matthew L, Carlson, Timothy, Coxon, Angela, Fajardo, Flordeliza, Frank, Brendon, Gustin, Darin, Kamb, Alexander, Kassner, Paul D, Li, Shyun, Li, Yihong, Morgenstern, Kurt, Plant, Matthew, Quon, Kim, Ruefli-Brasse, Astrid, Schmidt, Joanna, Swearingen, Elissa, Walker, Nigel, Wang, Zhulun, Watson, J E Vivienne, Wickramasinghe, Dineli, Wong, Mariwil, Xu, Guifen, Wesche, Holger

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Measurement of Cancer Cell Growth Heterogeneity through Lentiviral Barcoding Identifies Clonal Dominance as a Characteristic of In Vivo Tumor Engraftment von Nolan-Stevaux, Olivier, Tedesco, Donato, Ragan, Seamus, Makhanov, Mikhail, Chenchik, Alex, Ruefli-Brasse, Astrid, Quon, Kim, Kassner, Paul D

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Regulation of NF-κB-Dependent Lymphocyte Activation and Development by Paracaspase von Ruefli-Brasse, Astrid A., French, Dorothy M., Dixit, Vishva M.

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Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P‐glycoprotein‐expressing cells von Ruefli, Astrid A., Bernhard, David, Tainton, Kellie M., Kofler, Reinhard, Smyth, Mark J., Johnstone, Ricky W.

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The Growth Factor Midkine Antagonizes VEGF Signaling In Vitro and In Vivo von van der Horst, Edward Htun, Frank, Brendon T., Chinn, Lawrence, Coxon, Angela, Li, Shyun, Polesso, Fanny, Slavin, Anthony, Ruefli-Brasse, Astrid, Wesche, Holger

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Calcium Regulates Processing of the Alzheimer Amyloid Protein Precursor in a Protein Kinase C-Independent Manner von Buxbaum, Joseph D., Ruefli, Astrid A., Parker, Carolyn A., Cypess, Aaron M., Greengard, Paul

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Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation von Sutton, V R, Davis, J E, Cancilla, M, Johnstone, R W, Ruefli, A A, Sedelies, K, Browne, K A, Trapani, J A

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A role for P-glycoprotein in regulating cell growth and survival von Ruefli, Astrid A, Johnstone, Ricky W

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Tissue-Specific Immunoregulation: A Call for Better Understanding of the "Immunostat" in the Context of Cancer von Pao, William, Ooi, Chia-Huey, Birzele, Fabian, Ruefli-Brasse, Astrid, Cannarile, Michael A, Reis, Bernhard, Scharf, Sebastian H, Schubert, David A, Hatje, Klas, Pelletier, Nadege, Spleiss, Olivia, Reed, John C

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Abstract 1703: Sensitizing cancer cells to TNF induced cell death by the BET-inhibitor RG6146 von Wellinger, Lisa C., Hogg, Simon J., Newman, Dane, Friess, Thomas, Geiss, Daniela, Bacac, Marina, Fauti, Tanja, Ruefli-Brasse, Astrid, Johnstone, Ricky W., Rohle, Daniel

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P-glycoprotein Does Not Protect Cells against Cytolysis Induced by Pore-forming Proteins von Johnstone, Ricky W., Tainton, Kellie M., Ruefli, Astrid A., Froelich, Christopher J., Cerruti, Loretta, Jane, Stephen M., Smyth, Mark J.

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HMBA induces activation of a caspase-independent cell death pathway to overcome P-glycoprotein-mediated multidrug resistance von Ruefli, Astrid A., Smyth, Mark J., Johnstone, Ricky W.

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