How TCRs bind MHCs, peptides, and coreceptors von Rudolph, Markus G, Stanfield, Robyn L, Wilson, Ian A

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Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7 von Jaeger, Kathrin, Bruenle, Steffen, Weinert, Tobias, Guba, Wolfgang, Muehle, Jonas, Miyazaki, Takuya, Weber, Martin, Furrer, Antonia, Haenggi, Noemi, Tetaz, Tim, Huang, Chia-Ying, Mattle, Daniel, Vonach, Jean-Marie, Gast, Alain, Kuglstatter, Andreas, Rudolph, Markus G., Nogly, Przemyslaw, Benz, Joerg, Dawson, Roger J.P., Standfuss, Joerg

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D3R Grand Challenge 2: blind prediction of protein–ligand poses, affinity rankings, and relative binding free energies von Gaieb, Zied, Liu, Shuai, Gathiaka, Symon, Chiu, Michael, Yang, Huanwang, Shao, Chenghua, Feher, Victoria A., Walters, W. Patrick, Kuhn, Bernd, Rudolph, Markus G., Burley, Stephen K., Gilson, Michael K., Amaro, Rommie E.

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Mapping the Spectrum of Conformational States of the DNA- and C-Gates in Bacillus subtilis Gyrase von Rudolph, Markus G., Klostermeier, Dagmar

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Using macromolecular phasing and refinement techniques for a small molecule gyrase inhibitor von Rudolph, Markus G., Guba, Wolfgang, Xuefei, Tan, Xu, Bruce

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When core competence is not enough: functional interplay of the DEAD-box helicase core with ancillary domains and auxiliary factors in RNA binding and unwinding von Rudolph, Markus G., Klostermeier, Dagmar

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DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome von Richter, Hans, Satz, Alexander L, Bedoucha, Marc, Buettelmann, Bernd, Petersen, Ann C, Harmeier, Anja, Hermosilla, Ricardo, Hochstrasser, Remo, Burger, Dominique, Gsell, Bernard, Gasser, Rodolfo, Huber, Sylwia, Hug, Melanie N, Kocer, Buelent, Kuhn, Bernd, Ritter, Martin, Rudolph, Markus G, Weibel, Franziska, Molina-David, Judith, Kim, Jin-Ju, Santos, Javier Varona, Stihle, Martine, Georges, Guy J, Bonfil, R. Daniel, Fridman, Rafael, Uhles, Sabine, Moll, Solange, Faul, Christian, Fornoni, Alessia, Prunotto, Marco

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Discovery of a Series of Indane-Containing NBTIs with Activity against Multidrug-Resistant Gram-Negative Pathogens von Cumming, John G., Kreis, Lukas, Kühne, Holger, Wermuth, Roger, Vercruysse, Maarten, Kramer, Christian, Rudolph, Markus G., Xu, Zhiheng

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TIP47 functions in the biogenesis of lipid droplets von Bulankina, Anna V, Deggerich, Anke, Wenzel, Dirk, Mutenda, Kudzai, Wittmann, Julia G, Rudolph, Markus G, Burger, Koert N.J, Höning, Stefan

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Discovery of a microbial transglutaminase enabling highly site-specific labeling of proteins von Steffen, Wojtek, Ko, Fu Chong, Patel, Jigar, Lyamichev, Victor, Albert, Thomas J., Benz, Jörg, Rudolph, Markus G., Bergmann, Frank, Streidl, Thomas, Kratzsch, Peter, Boenitz-Dulat, Mara, Oelschlaegel, Tobias, Schraeml, Michael

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Structure of reverse gyrase with a minimal latch that supports ATP‐dependent positive supercoiling without specific interactions with the topoisomerase domain von Mhaindarkar, Vaibhav P., Rasche, René, Kümmel, Daniel, Rudolph, Markus G., Klostermeier, Dagmar

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A high quality, industrial data set for binding affinity prediction: performance comparison in different early drug discovery scenarios von Tosstorff, Andreas, Rudolph, Markus G., Cole, Jason C., Reutlinger, Michael, Kramer, Christian, Schaffhauser, Hervé, Nilly, Agnès, Flohr, Alexander, Kuhn, Bernd

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A Real-World Perspective on Molecular Design von Kuhn, Bernd, Guba, Wolfgang, Hert, Jérôme, Banner, David, Bissantz, Caterina, Ceccarelli, Simona, Haap, Wolfgang, Körner, Matthias, Kuglstatter, Andreas, Lerner, Christian, Mattei, Patrizio, Neidhart, Werner, Pinard, Emmanuel, Rudolph, Markus G, Schulz-Gasch, Tanja, Woltering, Thomas, Stahl, Martin

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Details Matter in Structure-based Drug Design von Kuhn, Bernd, Peters, Jens-Uwe, Rudolph, Markus G, Mohr, Peter, Stahl, Martin, Tosstorff, Andreas

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Ligand channel in pharmacologically stabilized rhodopsin von Mattle, Daniel, Kuhn, Bernd, Aebi, Johannes, Bedoucha, Marc, Kekilli, Demet, Grozinger, Nathalie, Alker, Andre, Rudolph, Markus G., Schmid, Georg, Schertler, Gebhard F. X., Hennig, Michael, Standfuss, Jörg, Dawson, Roger J. P.

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Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase von Baltgalvis, Kristen A., Lamb, Kelsey N., Symons, Kent T., Wu, Chu-Chiao, Hoffman, Melissa A., Snead, Aaron N., Song, Xiaodan, Glaza, Thomas, Kikuchi, Shota, Green, Jason C., Rogness, Donald C., Lam, Betty, Rodriguez-Aguirre, Maria E., Woody, David R., Eissler, Christie L., Rodiles, Socorro, Negron, Seth M., Bernard, Steffen M., Tran, Eileen, Pollock, Jonathan, Tabatabaei, Ali, Contreras, Victor, Williams, Heather N., Pastuszka, Martha K., Sigler, John J., Pettazzoni, Piergiorgio, Rudolph, Markus G., Classen, Moritz, Brugger, Doris, Claiborne, Christopher, Plancher, Jean-Marc, Cuartas, Isabel, Seoane, Joan, Burgess, Laurence E., Abraham, Robert T., Weinstein, David S., Simon, Gabriel M., Patricelli, Matthew P., Kinsella, Todd M.

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Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1 von Dawson, Roger J.P., Benz, Jörg, Stohler, Peter, Tetaz, Tim, Joseph, Catherine, Huber, Sylwia, Schmid, Georg, Hügin, Daniela, Pflimlin, Pascal, Trube, Gerd, Rudolph, Markus G., Hennig, Michael, Ruf, Armin

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Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain von Richter, Kirsten, Rufer, Arne C., Muller, Magali, Burger, Dominique, Casagrande, Fabio, Grossenbacher, Tabea, Huber, Sylwia, Hug, Melanie N., Koldewey, Philipp, D'Osualdo, Andrea, Schlatter, Daniel, Stoll, Theodor, Rudolph, Markus G.

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Mapping the conformational space accessible to catechol-O-methyltransferase von Ehler, Andreas, Benz, Jörg, Schlatter, Daniel, Rudolph, Markus G.

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Domain swap in the C‐terminal ubiquitin‐like domain of human doublecortin von Rufer, Arne C., Kusznir, Eric, Burger, Dominique, Stihle, Martine, Ruf, Armin, Rudolph, Markus G.

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