An Antisense CAG Repeat Transcript at JPH3 Locus Mediates Expanded Polyglutamine Protein Toxicity in Huntington's Disease-like 2 Mice von Wilburn, Brian, Rudnicki, Dobrila D., Zhao, Jing, Weitz, Tara Murphy, Cheng, Yin, Gu, Xiaofeng, Greiner, Erin, Park, Chang Sin, Wang, Nan, Sopher, Bryce L., La Spada, Albert R., Osmand, Alex, Margolis, Russell L., Sun, Yi E., Yang, X. William

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A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity von Khaled, Houda G., Feng, Hongxuan, Hu, Xin, Sun, Xin, Zheng, Wang, Li, Pan P., Rudnicki, Dobrila D., Ye, Wenjuan, Chen, Yu-Chi, Southall, Noel, Marugan, Juan, Ross, Christopher A., Ferrer, Marc, Henderson, Mark J., Margolis, Russell L.

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Loss of junctophilin-3 contributes to huntington disease-like 2 pathogenesis von Seixas, Ana I., Holmes, Susan E., Takeshima, Hiroshi, Pavlovich, Amira, Sachs, Nancy, Pruitt, Jennifer L., Silveira, Isabel, Ross, Christopher A., Margolis, Russell L., Rudnicki, Dobrila D.

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Phosphorodiamidate morpholino oligomers suppress mutant huntingtin expression and attenuate neurotoxicity von Sun, Xin, Marque, Leonard O, Cordner, Zachary, Pruitt, Jennifer L, Bhat, Manik, Li, Pan P, Kannan, Geetha, Ladenheim, Ellen E, Moran, Timothy H, Margolis, Russell L, Rudnicki, Dobrila D

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Extracellular RNA communication: A decade of NIH common fund support illuminates exRNA biology von Amolegbe, Sara M., Johnston, Nicolas C., Ambrosi, Angela, Ganguly, Aniruddha, Howcroft, T. Kevin, Kuo, Lillian S., Labosky, Patricia A., Rudnicki, Dobrila D., Satterlee, John S., Tagle, Danilo A., Happel, Christine

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Brain, blood, and iron: Perspectives on the roles of erythrocytes and iron in neurodegeneration von Prohaska, Rainer, Sibon, Ody C.M, Rudnicki, Dobrila D, Danek, Adrian, Hayflick, Susan J, Verhaag, Esther M, Vonk, Jan J, Margolis, Russell L, Walker, Ruth H

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Exploring Novel Biologically-Relevant Chemical Space Through Artificial Intelligence: The NCATS ASPIRE Program von Duncan, Katharine K, Rudnicki, Dobrila D, Austin, Christopher P, Tagle, Danilo A

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Assessing a peptidylic inhibitor-based therapeutic approach that simultaneously suppresses polyglutamine RNA- and protein-mediated toxicities in patient cells and Drosophila von Zhang, Qian, Tsoi, Ho, Peng, Shaohong, Li, Pan P, Lau, Kwok-Fai, Rudnicki, Dobrila D, Ngo, Jacky Chi-Ki, Chan, Ho Yin Edwin

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A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression von Chung, Daniel W., Rudnicki, Dobrila D., Yu, Lan, Margolis, Russell L.

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Diced triplets expose neurons to RISC von Rudnicki, Dobrila D, Margolis, Russell L, Pearson, Christopher E, Krzyzosiak, Wlodzimierz J

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ATXN2-AS, a gene antisense to ATXN2, is associated with spinocerebellar ataxia type 2 and amyotrophic lateral sclerosis von Li, Pan P., Sun, Xin, Xia, Guangbin, Arbez, Nicolas, Paul, Sharan, Zhu, Shanshan, Peng, H. Benjamin, Ross, Christopher A., Koeppen, Arnulf H., Margolis, Russell L., Pulst, Stefan M., Ashizawa, Tetsuo, Rudnicki, Dobrila D.

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RNA Toxicity and Perturbation of rRNA Processing in Spinocerebellar Ataxia Type 2 von Li, Pan P., Moulick, Roumita, Feng, Hongxuan, Sun, Xin, Arbez, Nicolas, Jin, Jing, Marque, Leonard O., Hedglen, Erin, Chan, H.Y. Edwin, Ross, Christopher A., Pulst, Stefan M., Margolis, Russell L., Woodson, Sarah, Rudnicki, Dobrila D.

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Mapping biologically active chemical space to accelerate drug discovery von Sittampalam, G. Sitta, Rudnicki, Dobrila D., Tagle, Danilo A., Simeonov, Anton, Austin, Christopher P.

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Pathogenic insights from Huntington's disease-like 2 and other Huntington's disease genocopies von Margolis, Russell L, Rudnicki, Dobrila D

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Absence of Acanthocytosis in Huntington's Disease-like 2: A Prospective Comparison with Huntington's Disease von Anderson, David G, Carmona, Sergio, Naidoo, Kubendran, Coetzer, Theresa L, Carr, Jonathan, Rudnicki, Dobrila D, Walker, Ruth H, Margolis, Russell L, Krause, Amanda

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Quantitative Proteomic Analysis Reveals Similarities between Huntington’s Disease (HD) and Huntington’s Disease-Like 2 (HDL2) Human Brains von Ratovitski, Tamara, Chaerkady, Raghothama, Kammers, Kai, Stewart, Jacqueline C, Zavala, Anialak, Pletnikova, Olga, Troncoso, Juan C, Rudnicki, Dobrila D, Margolis, Russell L, Cole, Robert N, Ross, Christopher A

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Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65 von Sun, Xin, Li, Pan P., Zhu, Shanshan, Cohen, Rachael, Marque, Leonard O., Ross, Christopher A., Pulst, Stefan M., Chan, Ho Yin Edwin, Margolis, Russell L., Rudnicki, Dobrila D.

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Neuropathology and Cellular Pathogenesis of Spinocerebellar Ataxia Type 12 von O'Hearn, Elizabeth E., Hwang, Hyon S., Holmes, Susan E., Rudnicki, Dobrila D., Chung, Daniel W., Seixas, Ana I., Cohen, Rachael L., Ross, Christopher A., Trojanowski, John Q., Pletnikova, Olga, Troncoso, Juan C., Margolis, Russell L.

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Huntington's disease-like 2 is associated with CUG repeat-containing RNA foci von Rudnicki, Dobrila D., Holmes, Susan E., Lin, Mark W., Thornton, Charles A., Ross, Christopher A., Margolis, Russell L.

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Eighth International Chorea-Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points von Pappas, Samuel S, Bonifacino, Juan, Danek, Adrian, Dauer, William T, De, Mithu, De Franceschi, Lucia, DiPaolo, Gilbert, Fuller, Robert, Haucke, Volker, Hermann, Andreas, Kornmann, Benoit, Landwehrmeyer, Bernhard, Levin, Johannes, Neiman, Aaron M, Rudnicki, Dobrila D, Sibon, Ody, Velayos-Baeza, Antonio, Vonk, Jan J, Walker, Ruth H, Weisman, Lois S, Albin, Roger L

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