Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations von Tamborero, David, Rubio-Perez, Carlota, Deu-Pons, Jordi, Schroeder, Michael P, Vivancos, Ana, Rovira, Ana, Tusquets, Ignasi, Albanell, Joan, Rodon, Jordi, Tabernero, Josep, de Torres, Carmen, Dienstmann, Rodrigo, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria

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In Silico Prescription of Anticancer Drugs to Cohorts of 28 Tumor Types Reveals Targeting Opportunities von Rubio-Perez, Carlota, Tamborero, David, Schroeder, Michael P., Antolín, Albert A., Deu-Pons, Jordi, Perez-Llamas, Christian, Mestres, Jordi, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria

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Molecular Diagnosis of Diffuse Gliomas through Sequencing of Cell-Free Circulating Tumor DNA from Cerebrospinal Fluid von Martínez-Ricarte, Francisco, Mayor, Regina, Martínez-Sáez, Elena, Rubio-Pérez, Carlota, Pineda, Estela, Cordero, Esteban, Cicuéndez, Marta, Poca, Maria A, López-Bigas, Nuria, Ramon Y Cajal, Santiago, Vieito, María, Carles, Joan, Tabernero, Josep, Vivancos, Ana, Gallego, Soledad, Graus, Francesc, Sahuquillo, Juan, Seoane, Joan

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Independent Component Analysis Uncovers the Landscape of the Bladder Tumor Transcriptome and Reveals Insights into Luminal and Basal Subtypes von Biton, Anne, Bernard-Pierrot, Isabelle, Lou, Yinjun, Krucker, Clémentine, Chapeaublanc, Elodie, Rubio-Pérez, Carlota, López-Bigas, Nuria, Kamoun, Aurélie, Neuzillet, Yann, Gestraud, Pierre, Grieco, Luca, Rebouissou, Sandra, de Reyniès, Aurélien, Benhamou, Simone, Lebret, Thierry, Southgate, Jennifer, Barillot, Emmanuel, Allory, Yves, Zinovyev, Andrei, Radvanyi, François

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Genetic and functional characterization of disease associations explains comorbidity von Rubio-Perez, Carlota, Guney, Emre, Aguilar, Daniel, Piñero, Janet, Garcia-Garcia, Javier, Iadarola, Barbara, Sanz, Ferran, Fernandez-Fuentes, Narcís, Furlong, Laura I., Oliva, Baldo

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A Pan-cancer Landscape of Interactions between Solid Tumors and Infiltrating Immune Cell Populations von Tamborero, David, Rubio-Perez, Carlota, Muiños, Ferran, Sabarinathan, Radhakrishnan, Piulats, Josep M, Muntasell, Aura, Dienstmann, Rodrigo, Lopez-Bigas, Nuria, Gonzalez-Perez, Abel

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Single-cell transcriptional changes associated with drug tolerance and response to combination therapies in cancer von Aissa, Alexandre F., Islam, Abul B. M. M. K., Ariss, Majd M., Go, Cammille C., Rader, Alexandra E., Conrardy, Ryan D., Gajda, Alexa M., Rubio-Perez, Carlota, Valyi-Nagy, Klara, Pasquinelli, Mary, Feldman, Lawrence E., Green, Stefan J., Lopez-Bigas, Nuria, Frolov, Maxim V., Benevolenskaya, Elizaveta V.

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Non-coding recurrent mutations in chronic lymphocytic leukaemia von Puente, Xose S., Beà, Silvia, Valdés-Mas, Rafael, Villamor, Neus, Gutiérrez-Abril, Jesús, Martín-Subero, José I., Munar, Marta, Rubio-Pérez, Carlota, Jares, Pedro, Aymerich, Marta, Baumann, Tycho, Beekman, Renée, Belver, Laura, Carrio, Anna, Castellano, Giancarlo, Clot, Guillem, Colado, Enrique, Colomer, Dolors, Costa, Dolors, Delgado, Julio, Enjuanes, Anna, Estivill, Xavier, Ferrando, Adolfo A., Gelpí, Josep L., González, Blanca, González, Santiago, González, Marcos, Gut, Marta, Hernández-Rivas, Jesús M., López-Guerra, Mónica, Martín-García, David, Navarro, Alba, Nicolás, Pilar, Orozco, Modesto, Payer, Ángel R., Pinyol, Magda, Pisano, David G., Puente, Diana A., Queirós, Ana C., Quesada, Víctor, Romeo-Casabona, Carlos M., Royo, Cristina, Royo, Romina, Rozman, María, Russiñol, Nuria, Salaverría, Itziar, Stamatopoulos, Kostas, Stunnenberg, Hendrik G., Tamborero, David, Terol, María J., Valencia, Alfonso, López-Bigas, Nuria, Torrents, David, Gut, Ivo, López-Guillermo, Armando, López-Otín, Carlos, Campo, Elías

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LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy von Pascual-García, Mónica, Bonfill-Teixidor, Ester, Planas-Rigol, Ester, Rubio-Perez, Carlota, Iurlaro, Raffaella, Arias, Alexandra, Cuartas, Isabel, Sala-Hojman, Ada, Escudero, Laura, Martínez-Ricarte, Francisco, Huber-Ruano, Isabel, Nuciforo, Paolo, Pedrosa, Leire, Marques, Carolina, Braña, Irene, Garralda, Elena, Vieito, María, Squatrito, Massimo, Pineda, Estela, Graus, Francesc, Espejo, Carmen, Sahuquillo, Juan, Tabernero, Josep, Seoane, Joan

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Cell free circulating tumor DNA in cerebrospinal fluid detects and monitors central nervous system involvement of B-cell lymphomas von Bobillo, Sabela, Crespo, Marta, Escudero, Laura, Mayor, Regina, Raheja, Priyanka, Carpio, Cecilia, Rubio-Perez, Carlota, Tazón-Vega, Bárbara, Palacio, Carlos, Carabia, Júlia, Jiménez, Isabel, Nieto, Juan C, Montoro, Julia, Martínez-Ricarte, Francisco, Castellvi, Josep, Simó, Marc, Puigdefàbregas, Lluis, Abrisqueta, Pau, Bosch, Francesc, Seoane, Joan

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Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma von Escudero, Laura, Llort, Anna, Arias, Alexandra, Diaz-Navarro, Ander, Martínez-Ricarte, Francisco, Rubio-Perez, Carlota, Mayor, Regina, Caratù, Ginevra, Martínez-Sáez, Elena, Vázquez-Méndez, Élida, Lesende-Rodríguez, Iván, Hladun, Raquel, Gros, Luis, Ramón y Cajal, Santiago, Poca, Maria A., Puente, Xose S., Sahuquillo, Juan, Gallego, Soledad, Seoane, Joan

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The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities von Boni, Jacopo, Rubio-Perez, Carlota, López-Bigas, Nuria, Fillat, Cristina, de la Luna, Susana

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Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment von Rubio-Perez, Carlota, Planas-Rigol, Ester, Trincado, Juan L., Bonfill-Teixidor, Ester, Arias, Alexandra, Marchese, Domenica, Moutinho, Catia, Serna, Garazi, Pedrosa, Leire, Iurlaro, Raffaella, Martínez-Ricarte, Francisco, Escudero, Laura, Cordero, Esteban, Cicuendez, Marta, Ruiz, Sara, Parra, Genís, Nuciforo, Paolo, Gonzalez, Josep, Pineda, Estela, Sahuquillo, Juan, Tabernero, Josep, Heyn, Holger, Seoane, Joan

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OncodriveROLE classifies cancer driver genes in loss of function and activating mode of action von Schroeder, Michael P, Rubio-Perez, Carlota, Tamborero, David, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria

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Rational design of cancer gene panels with OncoPaD von Rubio-Perez, Carlota, Deu-Pons, Jordi, Tamborero, David, Lopez-Bigas, Nuria, Gonzalez-Perez, Abel

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Pan-cancer analysis of whole genomes von Campbell, Peter J, Getz, Gad, Korbel, Jan O, Stuart, Joshua M, Jennings, Jennifer L, Stein, Lincoln D, Perry, Marc D

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Analyses of non-coding somatic drivers in 2,658 cancer whole genomes von Rheinbay, Esther, Nielsen, Morten Muhlig, Abascal, Federico, Wala, Jeremiah A., Shapira, Ofer, Tiao, Grace, Hornshøj, Henrik, Hess, Julian M., Juul, Randi Istrup, Lin, Ziao, Feuerbach, Lars, Sabarinathan, Radhakrishnan, Madsen, Tobias, Kim, Jaegil, Mularoni, Loris, Shuai, Shimin, Lanzós, Andrés, Herrmann, Carl, Maruvka, Yosef E., Shen, Ciyue, Amin, Samirkumar B., Bandopadhayay, Pratiti, Bertl, Johanna, Boroevich, Keith A., Busanovich, John, Carlevaro-Fita, Joana, Chakravarty, Dimple, Chan, Calvin Wing Yiu, Craft, David, Dhingra, Priyanka, Diamanti, Klev, Fonseca, Nuno A., Gonzalez-Perez, Abel, Guo, Qianyun, Hamilton, Mark P., Haradhvala, Nicholas J., Hong, Chen, Isaev, Keren, Johnson, Todd A., Juul, Malene, Kahles, Andre, Kahraman, Abdullah, Kim, Youngwook, Komorowski, Jan, Kumar, Kiran, Kumar, Sushant, Lee, Donghoon, Lehmann, Kjong-Van, Li, Yilong, Liu, Eric Minwei, Lochovsky, Lucas, Park, Keunchil, Pich, Oriol, Roberts, Nicola D., Saksena, Gordon, Schumacher, Steven E., Sidiropoulos, Nikos, Sieverling, Lina, Sinnott-Armstrong, Nasa, Stewart, Chip, Tamborero, David, Tubio, Jose M. C., Umer, Husen M., Uusküla-Reimand, Liis, Wadelius, Claes, Wadi, Lina, Yao, Xiaotong, Zhang, Cheng-Zhong, Zhang, Jing, Haber, James E., Hobolth, Asger, Imielinski, Marcin, Kellis, Manolis, Lawrence, Michael S., von Mering, Christian, Nakagawa, Hidewaki, Raphael, Benjamin J., Rubin, Mark A., Sander, Chris, Stein, Lincoln D., Stuart, Joshua M., Tsunoda, Tatsuhiko, Wheeler, David A., Johnson, Rory, Reimand, Jüri, Gerstein, Mark, Khurana, Ekta, Campbell, Peter J., López-Bigas, Núria, Weischenfeldt, Joachim, Beroukhim, Rameen, Martincorena, Iñigo, Pedersen, Jakob Skou, Getz, Gad

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Comprehensive Characterization of Cancer Driver Genes and Mutations von Colaprico, Antonio, Cao, Song, Liang, Wen-Wei, Hess, Julian M., Ferguson, Martin L., Hutter, Carolyn M., Tarnuzzer, Roy, Wang, Zhining, Noble, Michael S., Dhankani, Varsha, Knijnenburg, Theo, Miller, Michael, Abeshouse, Adam, Ladanyi, Marc, Luna, Augustin, Wong, Christopher K., Yau, Christina, Kasaian, Katayoon, Kucherlapati, Melanie H., Danilova, Ludmila, Bootwalla, Moiz S., Fan, Cheng, Mose, Lisle E., Roach, Jeffrey, Tan, Donghui, Covington, Kyle, Donehower, Lawrence A., Drummond, Jennifer, Liu, Xiuping, Morgan, Margaret, Wheeler, David A., Appelbaum, Elizabeth L., Bailey, Matthew, Kandoth, Cyriac, Wilson, Richard K., Penny, Robert, Thompson, Eric, Zmuda, Erik, de Carvalho, Ana C., Fregnani, José H., Huntsman, David, Kohl, Bernard, Paklina, Oxana, McPherson, Christopher, Barnholtz-Sloan, Jill S., Tucker, Kelinda, Larson, Caroline, Iacocca, Mary, Bergeron, Alain, Sepulveda, Antonia, Desjardins, Laurence, Sastre, Xavier, Cheng, Feixiong, Force, Seth, Khuri, Fadlo, Owonikoko, Taofeek, Korpershoek, Esther, Looijenga, Leendert, DiMeco, Francesco, Kycler, Witold, Chung, Ki, Noushmehr, Houtan, Scarpace, Lisa, Campo, Elias, Van Bang, Nguyen, Colman, Howard, Breggia, Anne, Bryce, Alan H., Copland, John A., Petersen, Gloria, Zhang, Lizhi, Mann, Graham, Mirsaidi, Cyrus, Zaren, Howard, Stancul, Irina, Tcaciuc, Diana, Arnaout, Angel, Rassl, Doris M., Urba, Walter, Farver, Carol, Raymond, Daniel, Dinkin, Mikhail, Carpino, Guido, Dubina, Michael, Abdel-Rahman, Mohamed H., Mandt, Randy, Nguyen, Phuong, Rai, Karan, Waldmann, Jens, Fassnacht, Martin, Simon, Ronald, Fehrenbach, Ashley, von Deimling, Andreas, Jacobus, Laura, Carlotti, Carlos Gilberto, Godwin, Eryn M., Carey, Thomas, Getz, Gad, Lazar, Alexander J., Ding, Li

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NK Cell Infiltrates and HLA Class I Expression in Primary HER2 + Breast Cancer Predict and Uncouple Pathological Response and Disease-free Survival von Muntasell, Aura, Rojo, Federico, Servitja, Sonia, Rubio-Perez, Carlota, Cabo, Mariona, Tamborero, David, Costa-García, Marcel, Martínez-Garcia, María, Menéndez, Sílvia, Vazquez, Ivonne, Lluch, Ana, Gonzalez-Perez, Abel, Rovira, Ana, López-Botet, Miguel, Albanell, Joan

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Severe SARS-CoV-2 placenta infection can impact neonatal outcome in the absence of vertical transmission von Cribiù, Fulvia Milena, Erra, Roberta, Pugni, Lorenza, Rubio-Perez, Carlota, Alonso, Lidia, Simonetti, Sara, Croci, Giorgio Alberto, Serna, Garazi, Ronchi, Andrea, Pietrasanta, Carlo, Lunghi, Giovanna, Fagnani, Anna Maria, Piñana, Maria, Matter, Matthias, Tzankov, Alexandar, Terracciano, Luigi, Anton, Andres, Ferrazzi, Enrico, Ferrero, Stefano, Iurlaro, Enrico, Seoane, Joan, Nuciforo, Paolo

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