Phase I/IIa trial of the mammalian target of rapamycin inhibitor ridaforolimus (AP23573; MK-8669) administered orally in patients with refractory or advanced malignancies and sarco... von Mita, M.M., Poplin, E., Britten, C.D., Tap, W.D., Rubin, E.H., Scott, B.B., Berk, L., Rivera, V.M., Loewy, J.W., Dodion, P., Haluska, F., Sarantopoulos, J., Mita, A., Tolcher, A.

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Cerebral amyloid deposition and diffuse plaques in normal aging : Evidence for presymptomatic and very mild Alzheimer's disease von MORRIS, J. C, STORANDT, M, MCKEEL, D. W, RUBIN, E. H, PRICE, J. L, GRANT, E. A, BERG, L

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Pembrolizumab KEYNOTE-001: an adaptive study leading to accelerated approval for two indications and a companion diagnostic von Kang, S.P., Gergich, K., Lubiniecki, G.M., de Alwis, D.P., Chen, C., Tice, M.A.B., Rubin, E.H.

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Absence of cognitive impairment or decline in preclinical Alzheimer's disease von GOLDMAN, W. P, PRICE, J. L, STORANDT, M, GRANT, E. A, MCKEEL, D. W, RUBIN, E. H, MORRIS, J. C

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A novel framework for evaluating biomarker response relationships in immuno-oncology (IO) von Evelhoch, J.L., Mogg, R., Cristescu, R., Aurora-Garg, D., Chow, L.Q., Loi, S., Catenacci, D.V.T., Matulonis, U.A., Ott, P.A., Antonarakis, E.S., Poehlein, C.H., Joe, A., Keefe, S.M., Kang, P., Karantza, V., Cheng, J., Rubin, E.H.

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Mechanisms of resistance to topoisomerase I-targeting drugs von Rasheed, Zeshaan A, Rubin, Eric H

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Mechanisms of Resistance to Camptothecins von SALEEM, AHAMED, EDWARDS, TROY K., RASHEED, ZESHAAN, RUBIN, ERIC H.

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A multicenter, randomized, placebo controlled, multiple-dose, safety and pharmacokinetic study of AIT-082 (Neotrofin™) in mild Alzheimer's disease patients von Grundman, M, Capparelli, E, Kim, H.T, Morris, J.C, Farlow, M, Rubin, E.H, Heidebrink, J, Hake, A, Ho, G, Schultz, A.N, Schafer, K, Houston, W, Thomas, R, Thal, L.J

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Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells von DESAI, Shyamal D, LI, Tsai-Kun, RODRIGUEZ-BAUMAN, Alexandra, RUBIN, Eric H, LIU, Leroy F

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Role for Nucleolin/Nsr1 in the Cellular Localization of Topoisomerase I von Edwards, Troy K., Saleem, Ahamed, Shaman, Jeffrey A., Dennis, Tracey, Gerigk, Claudia, Oliveros, Elder, Gartenberg, Marc R., Rubin, Eric H.

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Psychotic symptoms and the longitudinal course of senile dementia of the Alzheimer type von Drevets, Wayne C., Rubin, Eugene H.

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Transcription-Dependent Degradation of Topoisomerase I-DNA Covalent Complexes von Desai, Shyamal D., Zhang, Hui, Rodriguez-Bauman, Alexandra, Yang, Jin-Ming, Wu, Xiaohua, Gounder, Murugesan K., Rubin, Eric H., Liu, Leroy F.

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Selective cytotoxicity of topoisomerase-directed protoberberines against glioblastoma cells von Sanders, MarilynM, Liu, AngelaA, Li, Tsai-Kun, Wu, Hong-Yan, Desai, ShyamalD, Mao, Yong, Rubin, EricH, LaVoie, EdmondJ, Makhey, Darshan, Liu, LeroyF

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Mechanisms of resistance in a human cell line exposed to sequential topoisomerase poisoning von SALEEM, A, IBRAHIM, N, PATEL, M, LI, X.-G, GUPTA, E, MENDOZA, J, PANTAZIS, P, RUBIN, E. H

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Psychopathology of very mild dementia of the Alzheimer type von RUBIN, E. H, KINSCHERF, D. A

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Effects of nortriptyline on depression and glycemic control in diabetes: results of a double-blind, placebo-controlled trial von Lustman, P J, Griffith, L S, Clouse, R E, Freedland, K E, Eisen, S A, Rubin, E H, Carney, R M, McGill, J B

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Risk factors for high-dose cytarabine neurotoxicity: an analysis of a cancer and leukemia group B trial in patients with acute myeloid leukemia von RUBIN, E. H, ANDERSEN, J. W, BERG, D. T, SCHIFFER, C. A, MAYER, R. J, STONE, R. M

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Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen von Haluska, Paul, Saleem, Ahamed, Edwards, Troy K., Rubin, Eric H.

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The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor von Saleem, Ahamed, Dutta, Jayeeta, Malegaonkar, Diptee, Rasheed, Farheena, Rasheed, Zeshaan, Rajendra, Rajeev, Marshall, Henderson, Luo, Minje, Li, Honghua, Rubin, Eric H

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Involvement of amino acids 361 to 364 of human topoisomerase I in camptothecin resistance and enzyme catalysis von Li, Xi-Guang, Paul, Haluska, Yaw-Huei, Hsiang, Ajit, K.Bharti, Donald, W.Kufe, Leroy, F.Liu, Eric, H.Rubin

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