The peptide neuromedin U (NMU) is elevated in NYHA II and III heart failure von Healy, Vincent, O'Hora, Therese Ruane, Markos, Farouk

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Small and intermediate Ca2+-sensitive K+ channels do not play a role in vascular conductance during resting blood flow in the anaesthetised pig von Ruane-O’Hora, Therese, Markos, Farouk

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The vascular glycocalyx is not a mechanosensor in conduit arteries in the anesthetized pig von Ruane-O'Hora, Therese, Ahmeda, Ahmad, Markos, Farouk

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Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII von Gurda, Brittney L, De Guilhem De Lataillade, Adrien, Bell, Peter, Zhu, Yanqing, Yu, Hongwei, Wang, Ping, Bagel, Jessica, Vite, Charles H, Sikora, Tracey, Hinderer, Christian, Calcedo, Roberto, Yox, Alexander D, Steet, Richard A, Ruane, Therese, O'Donnell, Patricia, Gao, Guangping, Wilson, James M, Casal, Margret, Ponder, Katherine P, Haskins, Mark E

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What is the mechanism of flow-mediated arterial dilatation von Markos, Farouk, Ruane O'Hora, Therese, Noble, Mark IM

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Liver-directed gene therapy corrects cardiovascular lesions in feline mucopolysaccharidosis type I von Hinderer, Christian, Bell, Peter, Gurda, Brittney L., Wang, Qiang, Louboutin, Jean-Pierre, Zhu, Yanqing, Bagel, Jessica, O'Donnell, Patricia, Sikora, Tracey, Ruane, Therese, Wang, Ping, Haskins, Mark E., Wilson, James M.

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Platelets Do Not Alter Flow-Mediated Dilation or Arterial Conduction in vivo von Ruane-O’Hora, Therese, Markos, Farouk

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A novel lipid-based solid dispersion for enhancing oral bioavailability of Lycopene – In vivo evaluation using a pig model von Faisal, Waleed, Ruane-O’Hora, Therese, O’Driscoll, Caitriona M., Griffin, Brendan T.

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Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments von O’Shea, Joseph P., Faisal, Waleed, Ruane-O’Hora, Therese, Devine, Ken J., Kostewicz, Edmund S., O’Driscoll, Caitriona M., Griffin, Brendan T.

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Intrathecal Gene Therapy Corrects CNS Pathology in a Feline Model of Mucopolysaccharidosis I von Hinderer, Christian, Bell, Peter, Gurda, Brittney L, Wang, Qiang, Louboutin, Jean-Pierre, Zhu, Yanqing, Bagel, Jessica, O'Donnell, Patricia, Sikora, Tracey, Ruane, Therese, Wang, Ping, Haskins, Mark E, Wilson, James M

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Neonatal Systemic AAV Induces Tolerance to CNS Gene Therapy in MPS I Dogs and Nonhuman Primates von Hinderer, Christian, Bell, Peter, Louboutin, Jean-Pierre, Zhu, Yanqing, Yu, Hongwei, Lin, Gloria, Choa, Ruth, Gurda, Brittney L, Bagel, Jessica, O'Donnell, Patricia, Sikora, Tracey, Ruane, Therese, Wang, Ping, Tarantal, Alice F, Casal, Margret L, Haskins, Mark E, Wilson, James M

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Effect of clazosentan, a selective endothelin A receptor antagonist, and tezosentan, a dual endothelin A/B antagonist, on pulsatile shear stress induced constriction of the iliac i... von Ruane-O'Hora, Therese, Rae, Mark George, Markos, Farouk

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Small and intermediate Ca 2+ -sensitive K + channels do not play a role in vascular conductance during resting blood flow in the anaesthetised pig von Ruane-O'Hora, Therese, Markos, Farouk

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Evaluating the impact of systemic AAV9.cIDUA administration on brain pathology in MPS I dogs von Bell, Peter, Gurda, Brittney L., Zhu, Yanqing, Sikora, Tracey, Ruane, Therese, O'Donnell, Patricia, Haskins, Mark E., Wilson, James M.

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Pentosan polysulfate: New mechanistic insights and treatment of the mucopolysaccharidoses von Simonaro, Calogera M., Tomatsu, Shunji, Ge, Yi, Meng, Fanli, Frohbergh, Michael, Haskins, Mark E., Ruane, Therese, Wang, Raymond Y., Vera, Moin, Solyom, Alexander, Schuchman, Edward H.

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Pharmacodynamics, pharmacokinetics and biodistribution of recombinant human N-acetylgalactosamine 4-sulfatase after 6months of therapy in cats using different IV infusion durations von Ruane, Therese, Haskins, Mark, Cheng, Alphonsus, Wang, Ping, Aguirre, Gustavo, Knox, Van W. (Rafe), Qi, Yulan, Tompkins, Troy, O'Neill, Charles A.

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Adeno-associated virus vector-mediated gene therapy can effectively treat CNS and cardiac lesions and induce immune tolerance to the therapeutic enzyme in large animal models of mu... von Wilson, James M., Hinderer, Christian, Bell, Peter, Gurda, Brittney L., Wang, Qiang, Louboutin, Jean-Pierre, Zhu, Yanqing, Choa, Ruth, Lin, Gloria, Bagel, Jessica, O'Donnell, Patricia, Sikora, Tracey, Ruane, Therese, Wang, Ping, Haskins, Mark E.

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Gene therapy for mucopolysaccharidosis VII: evaluation of intrathecal rAAV vectors in the canine model von Gurda, Brittney, Wang, Ping, Bell, Peter, Bagel, Jessica, Sikora, Tracey, O'Donnell, Patricia, Zhu, Yanqing, Ruane, Therese, Calcedo, Roberto, Yu, Hongwei, Casal, Margret, Vite, Charles, Ponder, Katherine, Wilson, James, Haskins, Mark

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Intracisternal cyclodextrin ameliorates neurological dysfunction, increases survival time, and stops Purkinje cell death in feline Niemann–Pick type C1 disease von Vite, Charles H., Bagel, Jessica H., Swain, Gary P., Prociuk, Maria, Sikora, Tracey U., O'Donnell, Patricia, Ruane, Therese, Ward, Sarah, Crooks, Alexandra, Li, Su, Mauldin, Elizabeth, Stein, Veronika, Ory, Daniel S., Kao, Mark L., Davidson, Cristin, Vanier, Marie T., Walkely, Steven U.

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Transfusion of 28 Day-Old Leukoreduced or Non-Leukoreduced Stored Red Blood Cells Induces an Inflammatory Response in Healthy Dogs von Callan, Mary Beth, Patel, Reema T., Rux, Ann H., Bandyopadhyay, Sheila, Sireci, Anthony N., O’Donnell, Patricia A., Ruane, Therese, Sikora, Tracey, Marryott, Kimberly, Sachais, Bruce S., Hod, Eldad A.

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