Cationic Polymethacrylate-Modified Liposomes Significantly Enhanced Doxorubicin Delivery and Antitumor Activity von Wang, Wenxi, Shao, Anna, Zhang, Nan, Fang, Jinzhang, Ruan, Jennifer Jin, Ruan, Benfang Helen

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Click chemistry-based synthesis and anticancer activity evaluation of novel C-14 1,2,3-triazole dehydroabietic acid hybrids von Hou, Wei, Luo, Zhi, Zhang, Guanjun, Cao, Danhui, Li, Di, Ruan, Haoqiang, Ruan, Benfang Helen, Su, Lin, Xu, Hongtao

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Discovery of an Inhibitor for Bacterial 3-Mercaptopyruvate Sulfurtransferase that Synergistically Controls Bacterial Survival von Croppi, Giorgia, Zhou, Yueyang, Yang, Rong, Bian, Yunfei, Zhao, Mingtao, Hu, Youtian, Ruan, Benfang Helen, Yu, Jing, Wu, Fang

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Mono-sulfonated tetrazolium salt based NAD(P)H detection reagents suitable for dehydrogenase and real-time cell viability assays von Zhang, Wei, Zhu, Min, Wang, Feng, Cao, Danhui, Ruan, Jennifer Jin, Su, Weike, Ruan, Benfang Helen

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Identification of a diverse synthetic abietane diterpenoid library and insight into the structure-activity relationships for antibacterial activity von Hou, Wei, Zhang, Guanjun, Luo, Zhi, Li, Di, Ruan, Haoqiang, Ruan, Benfang Helen, Su, Lin, Xu, Hongtao

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Biomolecular Interaction Assays Identified Dual Inhibitors of Glutaminase and Glutamate Dehydrogenase That Disrupt Mitochondrial Function and Prevent Growth of Cancer Cells von Zhu, Min, Fang, Jinzhang, Zhang, Jingjing, Zhang, Zheng, Xie, Jianhui, Yu, Yan, Ruan, Jennifer Jin, Chen, Zhao, Hou, Wei, Yang, Gensheng, Su, Weike, Ruan, Benfang Helen

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Propylselen inhibits cancer cell growth by targeting glutamate dehydrogenase at the NADP+ binding site von Hou, Wei, Lu, Shiying, Zhao, Han, Yu, Yan, Xu, Haodong, Yu, Biao, Su, Lin, Lin, Chenshui, Ruan, Benfang Helen

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Diselenide Covalent Allosteric Inhibitors of Glutaminase with Strong In Vivo Anticancer Activity von Hou, Wei, Chen, Zhao, Pan, Chuqiao, Ni, Maowei, Ruan, Haoqiang, Song, Jun, Lu, Shiying, Bhasin, Aman, Ruan, Benfang Helen

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Design and synthesis of biotinylated Hexylselen as a probe to identify KGA allosteric inhibitors by a convenient biomolecular interaction assay von Hou, Wei, Fang, Jinzhang, Su, Lin, Ye, Hengyu, Ruan, Benfang Helen

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Ebselen: Mechanisms of Glutamate Dehydrogenase and Glutaminase Enzyme Inhibition von Yu, Yan, Jin, Yanhong, Zhou, Jie, Ruan, Haoqiang, Zhao, Han, Lu, Shiying, Zhang, Yue, Li, Di, Ji, Xiaoyun, Ruan, Benfang Helen

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Abstract 3947: Glutaminolysis inhibitors benzo[d][1,2]selenazol -3(2H)-one dimers completely disrupt mitochondrial function and showed early promise as effective antitumor agents w... von Ruan, Benfang Helen, Yu, Yan, Chen, Zhao, Jin, Yanhong, Fang, Jinzhang, Zhao, Han, Ruan, Jennifer

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Self-Assembled Micellar Glutaminase Allosteric Inhibitor for Effective Therapeutic Intervention von Fang, Jinzhang, Chen, Zhao, Li, Jinxiu, Li, Di, Wang, Wenxi, Ruan, Benfang Helen

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FITC-labeled d-glucose analog is suitable as a probe for detecting insulin-dependent glucose uptake von Su, Lin, Wu, Rui, Chen, Xinrou, Hou, Wei, Ruan, Benfang Helen

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Design and synthesis of novel tellurodibenzoic acid compounds as kidney-type glutaminase (KGA) inhibitors von Hou, Wei, Zhou, Yucheng, Rui, Jingjing, Bai, Ruisong, Bhasin, Aman K.K., Ruan, Benfang Helen

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A sensitive EZMTT method provides microscale, quantitative and high-throughput evaluation of drug efficacy in the treatment of Mycobacterium tuberculosis infectious diseases von Xie, Li, Chen, Zhao, Liu, Wei, Gu, Dongshi, Yu, Yan, Chen, Xinrou, Wu, Yefei, Xu, Ning, Xie, Jie, Zhao, Gang, Ruan, Benfang Helen

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Biomolecular interaction analysis for carbon nanotubes and for biocompatibility prediction von Chen, Xiaoping, Fang, Jinzhang, Cheng, Yun, Zheng, Jianhui, Zhang, Jingjing, Chen, Tao, Ruan, Benfang Helen

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Synthesis of Novel Kidney-Type Glutaminase Allosteric Inhibitors Targeting the Critical Lys-320 Residue von Song, Jun, Pan, Chuqiao, Li, Jinxiu, Bai, Ruisong, Zeng, Ziying, Han, Yunying, Chen, Zhao, Hou, Wei, Li, Yong, Ruan, Benfang Helen

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Ebselen Reversibly Inhibits Human Glutamate Dehydrogenase at the Catalytic Site von Jin, Yanhong, Li, Di, Lu, Shiying, Zhao, Han, Chen, Zhao, Hou, Wei, Ruan, Benfang Helen

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Rapid High-Throughput Assay Identified Gemcitabine and Derivatives As Potent Inhibitors Against Multidrug-Resistant Staphylococcus aureus von Chen, Zhao, Li, Jinxiu, Wan, Yue, Bai, Ruisong, Wang, Wenjuan, Gao, Xuan, Li, Di, Hu, Qingfeng, Li, Yong, Ruan, Benfang Helen

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Novel 1,3,4-Selenadiazole-Containing Kidney-Type Glutaminase Inhibitors Showed Improved Cellular Uptake and Antitumor Activity von Chen, Zhao, Li, Di, Xu, Ning, Fang, Jinzhang, Yu, Yan, Hou, Wei, Ruan, Haoqiang, Zhu, Panpan, Ma, Renchao, Lu, Shiying, Cao, Danhui, Wu, Rui, Ni, Mowei, Zhang, Wei, Su, Weike, Ruan, Benfang Helen

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