Periodontal disease is associated with increased gut colonization of pathogenic Haemophilus parainfluenzae in patients with Crohn’s disease von Sohn, Jiho, Li, Lu, Zhang, Lixia, Genco, Robert J., Falkner, Karen L., Tettelin, Hervé, Rowsam, Aryn M., Smiraglia, Dominic J., Novak, Jan M., Diaz, Patricia I., Sun, Yijun, Kirkwood, Keith L.

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Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy von Affronti, Hayley C., Rowsam, Aryn M., Pellerite, Anthony J., Rosario, Spencer R., Long, Mark D., Jacobi, Justine J., Bianchi-Smiraglia, Anna, Boerlin, Christoph S., Gillard, Bryan M., Karasik, Ellen, Foster, Barbara A., Moser, Michael, Wilton, John H., Attwood, Kristopher, Nikiforov, Mikhail A., Azabdaftari, Gissou, Pili, Roberto, Phillips, James G., Casero, Robert A., Smiraglia, Dominic J.

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Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer von Long, Mark D., Jacobi, Justine J., Singh, Prashant K., Llimos, Gerard, Wani, Sajad A., Rowsam, Aryn M., Rosario, Spencer R., Hoogstraat, Marlous, Linder, Simon, Kirk, Jason, Affronti, Hayley C., Bergman, Andries, Zwart, Wilbert, Campbell, Moray J., Smiraglia, Dominic J.

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Compromised phagosome maturation underlies RPE pathology in cell culture and whole animal models of Smith-Lemli-Opitz Syndrome von Ramachandra Rao, Sriganesh, Pfeffer, Bruce A., Más Gómez, Néstor, Skelton, Lara A., Keiko, Ueda, Sparrow, Janet R., Rowsam, Aryn M., Mitchell, Claire H., Fliesler, Steven J.

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JAZF1: A Metabolic Regulator of Sensitivity to a Polyamine-Targeted Therapy von Rosario, Spencer R, Jacobi, Justine J, Long, Mark D, Affronti, Hayley C, Rowsam, Aryn M, Smiraglia, Dominic J

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Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma von Bianchi-Smiraglia, Anna, Bagati, Archis, Fink, Emily E, Affronti, Hayley C, Lipchick, Brittany C, Moparthy, Sudha, Long, Mark D, Rosario, Spencer R, Lightman, Shivana M, Moparthy, Kalyana, Wolff, David W, Yun, Dong Hyun, Han, Zhannan, Polechetti, Anthony, Roll, Matthew V, Gitlin, Ilya I, Leonova, Katerina I, Rowsam, Aryn M, Kandel, Eugene S, Gudkov, Andrei V, Bergsagel, P Leif, Lee, Kelvin P, Smiraglia, Dominic J, Nikiforov, Mikhail A

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Abstract PO-037: Leveraging polyamine metabolic stress to enhance sensitivity to epigenetic therapy for prostate cancer von Rowsam, Aryn M., Affronti, Hayley C., Rosario, Spencer R., Long, Mark D.

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554: PERIODONTAL DISEASE INCREASES ORAL-GUT TRANSMISSION OF COLITOGENIC HAEMOPHILUS PARAINFLUENZAE IN CROHN'S DISEASE PATIENTS von Sohn, Jiho, Li, Lu, Zhang, Lixia, Falkner, Karen L., Tettelin, Hervé, Rowsam, Aryn, Smiraglia, Dominic, Novak, Jan M., Diaz-Moreno, Patricia, Sun, Yijun, Kirkwood, Keith L.

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Abstract B052: Leveraging the metabolic stress of polyamine biosynthesis in prostate cancer towards a novel therapeutic approach von Affronti, Hayley C., Pellerite, Anthony J., Rowsam, Aryn, Rosario, Spencer R., Casero, Robert A., Nikiforov, Mikhail A., Phillips, James, Smiraglia, Dominic J.

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Periodontal disease is associated with increased gut colonization of pathogenic Haemophilusparainfluenzae in patients with Crohn's disease von Sohn, Jiho, Li, Lu, Zhang, Lixia, Genco, Robert J, Falkner, Karen L, Tettelin, Hervé, Rowsam, Aryn M, Smiraglia, Dominic J, Novak, Jan M, Diaz, Patricia I, Sun, Yijun, Kirkwood, Keith L

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Compromised phagosome maturation underlies RPE pathology in cell culture and whole animal models of Smith-Lemli-Opitz Syndrome von Sriganesh Ramachandra Rao, Pfeffer, Bruce A., Néstor Más Gómez, Skelton, Lara A., Ueda Keiko, Sparrow, Janet R., Aryn M. Rowsam, Mitchell, Claire H., Fliesler, Steven J.

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