Protein kinase D3 modulates MMP1 and MMP13 expression in human chondrocytes von Baker, Jonathan, Falconer, Adrian M D, Wilkinson, David J, Europe-Finner, G Nicholas, Litherland, Gary J, Rowan, Andrew D

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Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases von Hui, Wang, Litherland, Gary J, Elias, Martina S, Kitson, Gareth I, Cawston, Tim E, Rowan, Andrew D, Young, David A

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Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts von Williams, Rachel C, Skelton, Andrew J, Todryk, Stephen M, Rowan, Andrew D, Preshaw, Philip M, Taylor, John J

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Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology von Huesa, Carmen, Ortiz, Ana C, Dunning, Lynette, McGavin, Laura, Bennett, Louise, McIntosh, Kathryn, Crilly, Anne, Kurowska-Stolarska, Mariola, Plevin, Robin, van ‘t Hof, Rob J, Rowan, Andrew D, McInnes, Iain B, Goodyear, Carl S, Lockhart, John C, Ferrell, William R

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Macrophage migration and invasion is regulated by MMP10 expression von Murray, Megan Y, Birkland, Timothy P, Howe, Jonathan D, Rowan, Andrew D, Fidock, Mark, Parks, William C, Gavrilovic, Jelena

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Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli von Hodgson, David, Rowan, Andrew D, Falciani, Francesco, Proctor, Carole J

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cAMP response element‐binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chond... von Bui, Catherine, Barter, Matt J., Scott, Jenny L., Xu, Yaobo, Galler, Martin, Reynard, Louise N., Rowan, Andrew D., Young, David A.

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Novel Gain-of-Function Mutation in Stat1 Sumoylation Site Leads to CMC/CID Phenotype Responsive to Ruxolitinib von Al Shehri, Tariq, Gilmour, Kimberly, Gothe, Florian, Loughlin, Sam, Bibi, Shahnaz, Rowan, Andrew D., Grainger, Angela, Mohanadas, Thivytra, Cant, Andrew J., Slatter, Mary A., Hambleton, Sophie, Lilic, Desa, Leahy, Timothy R.

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Class I Histone Deacetylase Inhibition Modulates Metalloproteinase Expression and Blocks Cytokine‐Induced Cartilage Degradation von Culley, Kirsty L., Hui, Wang, Barter, Matt J., Davidson, Rose K., Swingler, Tracey E., Destrument, Auriane P. M., Scott, Jenny L., Donell, Simon T., Fenwick, Steve, Rowan, Andrew D., Young, David A., Clark, Ian M.

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Cytokine-induced cysteine- serine-rich nuclear protein-1 (CSRNP1) selectively contributes to MMP1 expression in human chondrocytes von Macdonald, Christopher D, Falconer, Adrian M D, Chan, Chun Ming, Wilkinson, David J, Skelton, Andrew, Reynard, Louise, Litherland, Gary J, Europe-Finner, G Nicholas, Rowan, Andrew D

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Activity of matrix metalloproteinase‐9 against native collagen types I and III von Bigg, Heather F., Rowan, Andrew D., Barker, Michael D., Cawston, Tim E.

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The Mammalian Chitinase-like Lectin, YKL-40, Binds Specifically to Type I Collagen and Modulates the Rate of Type I Collagen Fibril Formation von Bigg, Heather F., Wait, Robin, Rowan, Andrew D., Cawston, Tim E.

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Glycogen Synthase Kinase 3 Inhibition Stimulates Human Cartilage Destruction and Exacerbates Murine Osteoarthritis von Litherland, Gary J., Hui, Wang, Elias, Martina S., Wilkinson, David J., Watson, Sharon, Huesa, Carmen, Young, David A., Rowan, Andrew D.

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Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage von Hui, Wang, Young, David A, Rowan, Andrew D, Xu, Xin, Cawston, Tim E, Proctor, Carole J

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Matrix Metalloproteinase 13 Expression in Response to Double‐Stranded RNA in Human Chondrocytes von Radwan, Marta, Gavriilidis, Christos, Robinson, John H., Davidson, Rose, Clark, Ian M., Rowan, Andrew D., Young, David A.

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Synergistic Collagenase Expression and Cartilage Collagenolysis Are Phosphatidylinositol 3-Kinase/Akt Signaling-dependent von Litherland, Gary J., Dixon, Craig, Lakey, Rachel L., Robson, Timothy, Jones, Debra, Young, David A., Cawston, Tim E., Rowan, Andrew D.

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Matrix metalloproteinase‐13 is fully activated by neutrophil elastase and inactivates its serpin inhibitor, alpha‐1 antitrypsin: Implications for osteoarthritis von Wilkinson, David J., Falconer, Adrian M. D., Wright, Helen L., Lin, Hua, Yamamoto, Kazuhiro, Cheung, Kathleen, Charlton, Sarah H., Arques, Maria del Carmen, Janciauskiene, Sabina, Refaie, Ramsay, Rankin, Kenneth S., Young, David A., Rowan, Andrew D.

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Cytokine-induced MMP13 Expression in Human Chondrocytes Is Dependent on Activating Transcription Factor 3 (ATF3) Regulation von Chan, Chun Ming, Macdonald, Christopher D., Litherland, Gary J., Wilkinson, David J., Skelton, Andrew, Europe-Finner, G. Nicholas, Rowan, Andrew D.

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Serine proteinases in the turnover of the cartilage extracellular matrix in the joint: implications for therapeutics von Wilkinson, David J, Arques, Maria del Carmen, Huesa, Carmen, Rowan, Andrew D

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Gain‐of‐function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC) von Zheng, Jie, Veerdonk, Frank L., Crossland, Katherine L., Smeekens, Sanne P., Chan, Chun M., Al Shehri, Tariq, Abinun, Mario, Gennery, Andrew R., Mann, Jelena, Lendrem, Dennis W., Netea, Mihai G., Rowan, Andrew D., Lilic, Desa

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