Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress von van Gisbergen, Marike W, Voets, An M, Biemans, Rianne, Hoffmann, Roland F, Drittij-Reijnders, Marie-José, Haenen, Guido R M M, Heijink, Irene H, Rouschop, Kasper M A, Dubois, Ludwig J, Lambin, Philippe

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Optimal selection of natural killer cells to kill myeloma: the role of HLA-E and NKG2A von Sarkar, Subhashis, van Gelder, Michel, Noort, Willy, Xu, Yunping, Rouschop, Kasper M. A., Groen, Richard, Schouten, Harry C., Tilanus, Marcel G. J., Germeraad, Wilfred T. V., Martens, Anton C. M., Bos, Gerard M. J., Wieten, Lotte

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EGFR signaling and autophagy dependence for growth, survival, and therapy resistance von Jutten, Barry, rouschop, Kasper

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Physiological Oxygen Levels Differentially Regulate Adipokine Production in Abdominal and Femoral Adipocytes from Individuals with Obesity Versus Normal Weight von Lempesis, Ioannis G, Hoebers, Nicole, Essers, Yvonne, Jocken, Johan W E, Rouschop, Kasper M A, Blaak, Ellen E, Manolopoulos, Konstantinos N, Goossens, Gijs H

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Hypoxic Activation of the PERK/eIF2α Arm of the Unfolded Protein Response Promotes Metastasis through Induction of LAMP3 von MUJCIC, Hilda, NAGELKERKE, Anika, KORITZINSKY, Marianne, WOUTERS, Bradly G, ROUSCHOP, Kasper M. A, CHUNG, Stephen, CHAUDARY, Naz, SPAN, Paul N, CLARKE, Blaise, MILOSEVIC, Michael, SYKES, Jenna, HILL, Richard P

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Protection against renal ischemia reperfusion injury by CD44 disruption von ROUSCHOP, Kasper M. A, ROELOFS, Joris J. T. H, CLAESSEN, Nike, DA COSTA MARTINS, Paula, ZWAGINGA, Jaap-Jan, PALS, Steven T, WEENING, Jan J, FLORQUIN, Sandrine

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The Immunomodulatory Role of Hypoxic Tumor-Derived Extracellular Vesicles von Beaumont, Joel E J, Beelen, Nicky A, Wieten, Lotte, Rouschop, Kasper M A

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Urothelial CD44 Facilitates Escherichia coli Infection of the Murine Urinary Tract von Rouschop, Kasper M. A, Sylva, Marc, Teske, Gwendoline J. D, Hoedemaeker, Inge, Pals, Steven T, Weening, Jan J, van der Poll, Tom, Florquin, Sandrine

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Chloroquine combined with concurrent radiotherapy and temozolomide for newly diagnosed glioblastoma: a phase IB trial von Compter, Inge, Eekers, Danielle B. P., Hoeben, Ann, Rouschop, Kasper M. A., Reymen, Bart, Ackermans, Linda, Beckervordersantforth, Jan, Bauer, Noel J. C., Anten, Monique M., Wesseling, Pieter, Postma, Alida A., De Ruysscher, Dirk, Lambin, Philippe

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Extracellular Vesicles as Transmitters of Hypoxia Tolerance in Solid Cancers von Zonneveld, Marijke I, Keulers, Tom G H, Rouschop, Kasper M A

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Endogenous tissue-type plasminogen activator is protective during ascending urinary tract infection von Roelofs, Joris J. T. H., Rouschop, Kasper M. A., Teske, Gwendoline J. D., Wagenaar, Gerry T. M., Claessen, Nike, Weening, Jan J., van der Poll, Tom, Florquin, Sandrine

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ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer von Keulers, Tom G., Koch, Alexander, van Gisbergen, Marike W., Barbeau, Lydie M.O., Zonneveld, Marijke I., de Jong, Monique C., Savelkouls, Kim G.M., Wanders, Roel G., Bussink, Johan, Melotte, Veerle, Rouschop, Kasper M.A.

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Level of Activation of the Unfolded Protein Response Correlates With Paneth Cell Apoptosis in Human Small Intestine Exposed to Ischemia/Reperfusion von Grootjans, Joep, Hodin, Caroline M, de Haan, Jacco–Juri, Derikx, Joep P.M, Rouschop, Kasper M.A, Verheyen, Fons K, van Dam, Ronald M, Dejong, Cornelis H.C, Buurman, Wim A, Lenaerts, Kaatje

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Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2 von Vaes, Nathalie, Schonkeren, Simone L, Rademakers, Glenn, Holland, Amy M, Koch, Alexander, Gijbels, Marion J, Keulers, Tom G, de Wit, Meike, Moonen, Laura, Van der Meer, Jaleesa R M, van den Boezem, Edith, Wolfs, Tim G A M, Threadgill, David W, Demmers, Jeroen, Fijneman, Remond J A, Jimenez, Connie R, Vanden Berghe, Pieter, Smits, Kim M, Rouschop, Kasper M A, Boesmans, Werend, Hofstra, Robert M W, Melotte, Veerle

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EGFRvIII expression triggers a metabolic dependency and therapeutic vulnerability sensitive to autophagy inhibition von Jutten, Barry, Keulers, Tom G., Peeters, Hanneke J. M., Schaaf, Marco B. E., Savelkouls, Kim G. M., Compter, Inge, Clarijs, Ruud, Schijns, Olaf E. M. G., Ackermans, Linda, Teernstra, Onno P. M., Zonneveld, Marijke I., Colaris, Resi M. E., Dubois, Ludwig, Vooijs, Marc A., Bussink, Johan, Sotelo, Julio, Theys, Jan, Lammering, Guido, Rouschop, Kasper M. A.

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Autophagy is required during cycling hypoxia to lower production of reactive oxygen species von Rouschop, Kasper M.A, Ramaekers, Chantal H.M.A, Schaaf, Marco B.E, Keulers, Tom G.H, Savelkouls, Kim G.M, Lambin, Philippe, Koritzinsky, Marianne, Wouters, Bradly G

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Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3 von Mujcic, Hilda, Rzymski, Tomasz, Rouschop, Kasper M.A, Koritzinsky, Marianne, Milani, Manuela, Harris, Adrian L, Wouters, Bradly G

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Pre-transplant plasma and cellular levels of CD44 correlate with acute renal allograft rejection von Rouschop, Kasper M. A., Roelofs, Joris J. T. H., Rowshani, Ajda T., Leemans, Jaklien C., van der Poll, Tom, ten Berge, Ineke J. M., Weening, Jan J., Florquin, Sandrine

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The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia von Schaaf, Marco B.E, Cojocari, Dan, Keulers, Tom G, Jutten, Barry, Starmans, Maud H, de Jong, Monique C, Begg, Adrian C, Savelkouls, Kim G.M, Bussink, Johan, Vooijs, Marc, Wouters, Bradly G, Rouschop, Kasper M.A

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GABARAPL1 is required for increased EGFR membrane expression during hypoxia von Keulers, Tom G, Schaaf, Marco B.E, Peeters, Hanneke J.M, Savelkouls, Kim G.M, Vooijs, Marc A, Bussink, Johan, Jutten, Barry, Rouschop, Kasper M.A

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