LC3/GABARAP family proteins: autophagy‐(un)related functions von Schaaf, Marco B. E., Keulers, Tom G., Vooijs, Marc A., Rouschop, Kasper M. A.

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EGFR signaling and autophagy dependence for growth, survival, and therapy resistance von Jutten, Barry, rouschop, Kasper

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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5 von Rouschop, Kasper M A, van den Beucken, Twan, Dubois, Ludwig, Niessen, Hanneke, Bussink, Johan, Savelkouls, Kim, Keulers, Tom, Mujcic, Hilda, Landuyt, Willy, Voncken, Jan Willem, Lambin, Philippe, van der Kogel, Albert J, Koritzinsky, Marianne, Wouters, Bradly G

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Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells von Bowler, Elizabeth, Porazinski, Sean, Uzor, Simon, Thibault, Philippe, Durand, Mathieu, Lapointe, Elvy, Rouschop, Kasper M A, Hancock, John, Wilson, Ian, Ladomery, Michael

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Hypoxia induced impairment of NK cell cytotoxicity against multiple myeloma can be overcome by IL-2 activation of the NK cells von Sarkar, Subhashis, Germeraad, Wilfred T V, Rouschop, Kasper M A, Steeghs, Elisabeth M P, van Gelder, Michel, Bos, Gerard M J, Wieten, Lotte

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Chloroquine combined with concurrent radiotherapy and temozolomide for newly diagnosed glioblastoma: a phase IB trial von Compter, Inge, Eekers, Danielle B. P., Hoeben, Ann, Rouschop, Kasper M. A., Reymen, Bart, Ackermans, Linda, Beckervordersantforth, Jan, Bauer, Noel J. C., Anten, Monique M., Wesseling, Pieter, Postma, Alida A., De Ruysscher, Dirk, Lambin, Philippe

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Hypoxic Activation of the PERK/eIF2α Arm of the Unfolded Protein Response Promotes Metastasis through Induction of LAMP3 von MUJCIC, Hilda, NAGELKERKE, Anika, KORITZINSKY, Marianne, WOUTERS, Bradly G, ROUSCHOP, Kasper M. A, CHUNG, Stephen, CHAUDARY, Naz, SPAN, Paul N, CLARKE, Blaise, MILOSEVIC, Michael, SYKES, Jenna, HILL, Richard P

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Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress von van Gisbergen, Marike W, Voets, An M, Biemans, Rianne, Hoffmann, Roland F, Drittij-Reijnders, Marie-José, Haenen, Guido R M M, Heijink, Irene H, Rouschop, Kasper M A, Dubois, Ludwig J, Lambin, Philippe

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Extracellular Vesicles as Transmitters of Hypoxia Tolerance in Solid Cancers von Zonneveld, Marijke I, Keulers, Tom G H, Rouschop, Kasper M A

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Iron deficiency‐induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria‐containing vesicles von Leermakers, Pieter A., Remels, Alexander H. V., Zonneveld, Marijke I., Rouschop, Kasper M. A., Schols, Annemie M. W. J., Gosker, Harry R.

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Optimal selection of natural killer cells to kill myeloma: the role of HLA-E and NKG2A von Sarkar, Subhashis, van Gelder, Michel, Noort, Willy, Xu, Yunping, Rouschop, Kasper M. A., Groen, Richard, Schouten, Harry C., Tilanus, Marcel G. J., Germeraad, Wilfred T. V., Martens, Anton C. M., Bos, Gerard M. J., Wieten, Lotte

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PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS von Rouschop, Kasper M., Dubois, Ludwig J., Keulers, Tom G., van den Beucken, Twan, Lambin, Philippe, Bussink, Johan, van der Kogel, Albert J., Koritzinsky, Marianne, Wouters, Bradly G.

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Level of Activation of the Unfolded Protein Response Correlates With Paneth Cell Apoptosis in Human Small Intestine Exposed to Ischemia/Reperfusion von Grootjans, Joep, Hodin, Caroline M, de Haan, Jacco–Juri, Derikx, Joep P.M, Rouschop, Kasper M.A, Verheyen, Fons K, van Dam, Ronald M, Dejong, Cornelis H.C, Buurman, Wim A, Lenaerts, Kaatje

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Autophagy is required during cycling hypoxia to lower production of reactive oxygen species von Rouschop, Kasper M.A, Ramaekers, Chantal H.M.A, Schaaf, Marco B.E, Keulers, Tom G.H, Savelkouls, Kim G.M, Lambin, Philippe, Koritzinsky, Marianne, Wouters, Bradly G

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ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer von Keulers, Tom G., Koch, Alexander, van Gisbergen, Marike W., Barbeau, Lydie M.O., Zonneveld, Marijke I., de Jong, Monique C., Savelkouls, Kim G.M., Wanders, Roel G., Bussink, Johan, Melotte, Veerle, Rouschop, Kasper M.A.

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GABARAPL1 is essential in extracellular vesicle cargo loading and metastasis development von Beaumont, Joel E.J., Ju, Jinzhe, Barbeau, Lydie M.O., Demers, Imke, Savelkouls, Kim G., Derks, Kasper, Bouwman, Freek G., Wauben, Marca H.M., Zonneveld, Marijke I., Keulers, Tom G.H., Rouschop, Kasper M.A.

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Tumors Responsive to Autophagy-Inhibition: Identification and Biomarkers von Barbeau, Lydie M. O., Keulers, Tom G. H., Rouschop, Kasper M. A.

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Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3 von Mujcic, Hilda, Rzymski, Tomasz, Rouschop, Kasper M.A, Koritzinsky, Marianne, Milani, Manuela, Harris, Adrian L, Wouters, Bradly G

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Secretion of pro‐angiogenic extracellular vesicles during hypoxia is dependent on the autophagy‐related protein GABARAPL1 von Keulers, Tom G., Libregts, Sten F., Beaumont, Joel E.J., Savelkouls, Kim G., Bussink, Johan, Duimel, Hans, Dubois, Ludwig, Zonneveld, Marijke I., López‐Iglesias, Carmen, Bezstarosti, Karel, Demmers, Jeroen A., Vooijs, Marc, Wauben, Marca, Rouschop, Kasper M.A.

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Autophagy-Dependent Secretion: Contribution to Tumor Progression von Keulers, Tom G, Schaaf, Marco B E, Rouschop, Kasper M A

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