Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes von Rotroff, DM, Shahin, MH, Gurley, SB, Zhu, H, Motsinger‐Reif, A, Meisner, M, Beitelshees, AL, Fiehn, O, Johnson, JA, Elbadawi‐Sidhu, M, Frye, RF, Gong, Y, Weng, L, Cooper‐DeHoff, RM, Kaddurah‐Daouk, R

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Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting anti... von Rotroff, D M, Corum, D G, Motsinger-Reif, A, Fiehn, O, Bottrel, N, Drevets, W C, Singh, J, Salvadore, G, Kaddurah-Daouk, R

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The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: effects of estradiol and progesterone addback von Nguyen, T V, Reuter, J M, Gaikwad, N W, Rotroff, D M, Kucera, H R, Motsinger-Reif, A, Smith, C P, Nieman, L K, Rubinow, D R, Kaddurah-Daouk, R, Schmidt, P J

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Response to "Accurate Risk-Based Chemical Screening Relies on Robust Exposure Estimates" von Wetmore, B. A., Wambaugh, J. F., Ferguson, S. S., Sochaski, M. A., Rotroff, D. M., Freeman, K., Clewell, H. J., Dix, D. J., Andersen, M. E., Houck, K. A., Allen, B., Judson, R. S., Singh, R., Kavlock, R. J., Richard, A. M., Thomas, R. S.

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Impacts of COVID-19 on Glycemia and Risk of Diabetic Ketoacidosis von Sharma, Anukriti, Misra-Hebert, Anita D, Mariam, Arshiya, Milinovich, Alex, Onuzuruike, Anthony, Koomson, Wilhemina, Kattan, Michael W, Pantalone, Kevin M, Rotroff, Daniel M

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Metabolic network failures in Alzheimer's disease—A biochemical road map von Toledo, Jon B, Arnold, Matthias, Kastenmüller, Gabi, Chang, Rui, Baillie, Rebecca A, Han, Xianlin, Thambisetty, Madhav, Tenenbaum, Jessica D, Suhre, Karsten, Thompson, J. Will, John-Williams, Lisa St, MahmoudianDehkordi, Siamak, Rotroff, Daniel M, Jack, John R, Motsinger-Reif, Alison, Risacher, Shannon L, Blach, Colette, Lucas, Joseph E, Massaro, Tyler, Louie, Gregory, Zhu, Hongjie, Dallmann, Guido, Klavins, Kristaps, Koal, Therese, Kim, Sungeun, Nho, Kwangsik, Shen, Li, Casanova, Ramon, Varma, Sudhir, Legido-Quigley, Cristina, Moseley, M. Arthur, Zhu, Kuixi, Henrion, Marc Y.R, van der Lee, Sven J, Harms, Amy C, Demirkan, Ayse, Hankemeier, Thomas, van Duijn, Cornelia M, Trojanowski, John Q, Shaw, Leslie M, Saykin, Andrew J, Weiner, Michael W, Doraiswamy, P. Murali, Kaddurah-Daouk, Rima

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Plasma metabolomic differences in early-onset compared to average-onset colorectal cancer von Jayakrishnan, Thejus, Mariam, Arshiya, Farha, Nicole, Rotroff, Daniel M., Aucejo, Federico, Barot, Shimoli V., Conces, Madison, Nair, Kanika G., Krishnamurthi, Smitha S., Schmit, Stephanie L., Liska, David, Khorana, Alok A., Kamath, Suneel D.

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Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin von Zhou, Kaixin, Yee, Sook Wah, Seiser, Eric L, van Leeuwen, Nienke, Tavendale, Roger, Bennett, Amanda J, Groves, Christopher J, Coleman, Ruth L, van der Heijden, Amber A, Beulens, Joline W, de Keyser, Catherine E, Zaharenko, Linda, Rotroff, Daniel M, Out, Mattijs, Jablonski, Kathleen A, Chen, Ling, Javorský, Martin, Židzik, Jozef, Levin, Albert M, Williams, L Keoki, Dujic, Tanja, Semiz, Sabina, Kubo, Michiaki, Chien, Huan-Chieh, Maeda, Shiro, Witte, John S, Wu, Longyang, Tkáč, Ivan, Kooy, Adriaan, van Schaik, Ron H N, Stehouwer, Coen D A, Logie, Lisa, Sutherland, Calum, Klovins, Janis, Pirags, Valdis, Hofman, Albert, Stricker, Bruno H, Motsinger-Reif, Alison A, Wagner, Michael J, Innocenti, Federico, Hart, Leen M 't, Holman, Rury R, McCarthy, Mark I, Hedderson, Monique M, Palmer, Colin N A, Florez, Jose C, Giacomini, Kathleen M, Pearson, Ewan R

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A Multimodal Approach to Discover Biomarkers for Taxane-Induced Peripheral Neuropathy (TIPN): A Study Protocol von Sharma, Anukriti, Johnson, Ken B., Bie, Bihua, Rhoades, Emily E., Sen, Alper, Kida, Yuri, Hockings, Jennifer, Gatta, Alycia, Davenport, Jacqueline, Arcangelini, Connie, Ritzu, Jennifer, DeVecchio, Jennifer, Hughen, Ron, Wei, Mei, Thomas Budd, G., Lynn Henry, N., Eng, Charis, Foss, Joseph, Rotroff, Daniel M.

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Bariatric Surgery Improves HDL Function Examined by ApoA1 Exchange Rate and Cholesterol Efflux Capacity in Patients with Obesity and Type 2 Diabetes von Lorkowski, Shuhui Wang, Brubaker, Gregory, Rotroff, Daniel M, Kashyap, Sangeeta R, Bhatt, Deepak L, Nissen, Steven E, Schauer, Philip R, Aminian, Ali, Smith, Jonathan D

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795-P: Elucidating the Role of Weight Loss and Glycemia with Observed Benefits of GLP-1 Receptor Agonist Treatment in Patients with T2D von SHARMA, ANUKRITI, MARIAM, ARSHIYA, ZACHERLE, EMILY, MILINOVICH, ALEX, BAUMAN, JANINE, SUGANO, DAVID S., NOONE, JOSHUA, RAJPURA, JIGAR R., ZIMMERMAN, ROBERT S., BURGUERA, BARTO, KATTAN, MICHAEL, MISRA-HEBERT, ANITA D., PANTALONE, KEVIN M., ROTROFF, DANIEL M.

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Elucidating the role of weight loss and glycaemic control in patients with type 2 diabetes von Sharma, Anukriti, Mariam, Arshiya, Zacherle, Emily, Milinovich, Alex, Bauman, Janine, Sugano, David S., Noone, Josh, Rajpura, Jigar R., Zimmerman, Robert S., Burguera, Bartolome, Kattan, Michael W., Misra‐Hebert, Anita D., Pantalone, Kevin M., Rotroff, Daniel M.

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Adaptive selection at G6PD and disparities in diabetes complications von Breeyear, Joseph H., Hellwege, Jacklyn N., Schroeder, Philip H., House, John S., Poisner, Hannah M., Mitchell, Sabrina L., Charest, Brian, Khakharia, Anjali, Basnet, Til B., Halladay, Christopher W., Reaven, Peter D., Meigs, James B., Rhee, Mary K., Sun, Yang, Lynch, Mary G., Bick, Alexander G., Wilson, Otis D., Hung, Adriana M., Nealon, Cari L., Iyengar, Sudha K., Rotroff, Daniel M., Buse, John B., Leong, Aaron, Mercader, Josep M., Sobrin, Lucia, Brantley, Milam A., Peachey, Neal S., Motsinger-Reif, Alison A., Wilson, Peter W., Sun, Yan V., Giri, Ayush, Phillips, Lawrence S., Edwards, Todd L.

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Associations of weight loss with obesity‐related comorbidities in a large integrated health system von Mariam, Arshiya, Miller‐Atkins, Galen, Pantalone, Kevin M., Iyer, Neeraj, Misra‐Hebert, Anita D., Milinovich, Alex, Bauman, Janine, Mocarski, Michelle, Ramasamy, Abhilasha, Smolarz, B. Gabriel, Hobbs, Todd M., Zimmerman, Robert S., Burguera, Bartolome, Kattan, Michael W., Rotroff, Daniel M.

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Metagenomics and chemotherapy‐induced nausea: A roadmap for future research von Crowder, Sylvia L., Hoogland, Aasha I., Welniak, Taylor L., LaFranchise, Elizabeth A., Carpenter, Kristen M., Li, Daneng, Rotroff, Daniel M., Mariam, Arshiya, Pierce, Christine M., Fischer, Stacy M., Kinney, Anita Y., Dong‐Binh Tran, Thi, Rastegari, Farzaneh, Berry, Donna L., Extermann, Martine, Kim, Richard D., Tometich, Danielle B., Figueiredo, Jane C., Muzaffar, Jameel, Bari, Shahla, Turner, Kea, Weinstock, George M., Jim, Heather S. L.

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Targeted metabolomics and medication classification data from participants in the ADNI1 cohort von St John-Williams, Lisa, Blach, Colette, Toledo, Jon B., Rotroff, Daniel M., Kim, Sungeun, Klavins, Kristaps, Baillie, Rebecca, Han, Xianlin, Mahmoudiandehkordi, Siamak, Jack, John, Massaro, Tyler J., Lucas, Joseph E., Louie, Gregory, Motsinger-Reif, Alison A., Risacher, Shannon L., Saykin, Andrew J., Kastenmüller, Gabi, Arnold, Matthias, Koal, Therese, Moseley, M. Arthur, Mangravite, Lara M., Peters, Mette A., Tenenbaum, Jessica D., Thompson, J. Will, Kaddurah-Daouk, Rima

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Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome von MahmoudianDehkordi, Siamak, Arnold, Matthias, Nho, Kwangsik, Ahmad, Shahzad, Jia, Wei, Xie, Guoxiang, Louie, Gregory, Kueider-Paisley, Alexandra, Moseley, M. Arthur, Thompson, J. Will, St John Williams, Lisa, Tenenbaum, Jessica D., Blach, Colette, Baillie, Rebecca, Han, Xianlin, Bhattacharyya, Sudeepa, Toledo, Jon B., Schafferer, Simon, Klein, Sebastian, Koal, Therese, Risacher, Shannon L., Kling, Mitchel Allan, Motsinger-Reif, Alison, Rotroff, Daniel M., Jack, John, Hankemeier, Thomas, Bennett, David A., De Jager, Philip L., Trojanowski, John Q., Shaw, Leslie M., Weiner, Michael W., Doraiswamy, P. Murali, van Duijn, Cornelia M., Saykin, Andrew J., Kastenmüller, Gabi, Kaddurah-Daouk, Rima

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Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome‐Wide Interaction Meta‐Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studie... von McDonough, Caitrin W., Warren, Helen R., Jack, John R., Motsinger‐Reif, Alison A., Armstrong, Nicole D., Bis, Joshua C., House, John S., Singh, Sonal, El Rouby, Nihal M., Gong, Yan, Mychaleckyj, Joesyf C., Rotroff, Daniel M., Benavente, Oscar R., Caulfield, Mark J., Doria, Alessandrio, Pepine, Carl J., Psaty, Bruce M., Glorioso, Valeria, Glorioso, Nicola, Hiltunen, Timo P., Kontula, Kimmo K., Arnett, Donna K., Buse, John B., Irvin, Marguerite R., Johnson, Julie A., Munroe, Patricia B., Wagner, Michael J., Cooper‐DeHoff, Rhonda M.

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Circulating Gut Microbe-Derived Metabolites Are Associated with Hepatocellular Carcinoma von Banerjee, Rakhee, Wehrle, Chase J, Wang, Zeneng, Wilcox, Jennifer D, Uppin, Vinayak, Varadharajan, Venkateshwari, Mrdjen, Marko, Hershberger, Courtney, Reizes, Ofer, Yu, Jennifer S, Lathia, Justin D, Rotroff, Daniel M, Hazen, Stanley L, Tang, W H Wilson, Aucejo, Federico, Brown, J Mark

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Multi-omics machine learning to study host-microbiome interactions in early-onset colorectal cancer von Jayakrishnan, Thejus T., Sangwan, Naseer, Barot, Shimoli V., Farha, Nicole, Mariam, Arshiya, Xiang, Shao, Aucejo, Federico, Conces, Madison, Nair, Kanika G., Krishnamurthi, Smitha S., Schmit, Stephanie L., Liska, David, Rotroff, Daniel M., Khorana, Alok A., Kamath, Suneel D.

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