Molecular Mechanisms of PLD Function in Membrane Traffic von Roth, Michael G

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Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer von Lum, Lawrence, Chen, Baozhi, Dodge, Michael E, Tang, Wei, Lu, Jianming, Ma, Zhiqiang, Fan, Chih-Wei, Wei, Shuguang, Hao, Wayne, Kilgore, Jessica, Williams, Noelle S, Roth, Michael G, Amatruda, James F, Chen, Chuo

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Phosphoinositides in Constitutive Membrane Traffic von Roth, Michael G

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Systematic Identification of Molecular Subtype-Selective Vulnerabilities in Non-Small-Cell Lung Cancer von Kim, Hyun Seok, Mendiratta, Saurabh, Kim, Jiyeon, Pecot, Chad Victor, Larsen, Jill E., Zubovych, Iryna, Seo, Bo Yeun, Kim, Jimi, Eskiocak, Banu, Chung, Hannah, McMillan, Elizabeth, Wu, Sherry, De Brabander, Jef, Komurov, Kakajan, Toombs, Jason E., Wei, Shuguang, Peyton, Michael, Williams, Noelle, Gazdar, Adi F., Posner, Bruce A., Brekken, Rolf A., Sood, Anil K., Deberardinis, Ralph J., Roth, Michael G., Minna, John D., White, Michael A.

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Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway von Wang, May-Yun, Yan, Hai, Shi, Zhiqing, Evans, Matthew R., Yu, Xinxin, Lee, Young, Chen, Shiuhwei, Williams, Annie, Philippe, Jacques, Roth, Michael G., Unger, Roger H.

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SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers von Tagal, Vural, Wei, Shuguang, Zhang, Wei, Brekken, Rolf A., Posner, Bruce A., Peyton, Michael, Girard, Luc, Hwang, TaeHyun, Wheeler, David A., Minna, John D., White, Michael A., Gazdar, Adi F., Roth, Michael G.

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A New Biology of Diabetes Revealed by Leptin von Unger, Roger H., Roth, Michael G.

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Synthetic lethal screen identification of chemosensitizer loci in cancer cells von Peyton, Michael, Bodemann, Brian O, Minna, John D, Hao, Weihua, Ferguson, Deborah, White, Michael A, Xie, Xian-Jin, Cardenas, Jessica, Roth, Michael G, Girard, Luc, Michnoff, Carolyn, Whitehurst, Angelique W

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Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells von Lee, Young, Berglund, Eric D., Yu, Xinxin, Wang, May-Yun, Evans, Matthew R., Scherer, Philipp E., Holland, William L., Charron, Maureen J., Roth, Michael G., Unger, Roger H.

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Loss of Aurora Kinase Signaling Allows Lung Cancer Cells to Adopt Endoreplication and Form Polyploid Giant Cancer Cells That Resist Antimitotic Drugs von Tagal, Vural, Roth, Michael G.

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Phosphatidylinositol 4 Phosphate Regulates Targeting of Clathrin Adaptor AP-1 Complexes to the Golgi von Wang, Ying Jie, Wang, Jing, Sun, Hui Qiao, Martinez, Manuel, Sun, Yu Xiao, Macia, Eric, Kirchhausen, Tomas, Albanesi, Joseph P., Roth, Michael G., Yin, Helen L.

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Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells von Ganesan, Anand K, Ho, Hsiang, Bodemann, Brian, Petersen, Sean, Aruri, Jayavani, Koshy, Shiney, Richardson, Zachary, Le, Lu Q, Krasieva, Tatiana, Roth, Michael G, Farmer, Pat, White, Michael A

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Small molecule glucagon release inhibitors with activity in human islets von Kalwat, Michael A, Rodrigues-Dos-Santos, Karina, Binns, Derk D, Wei, Shuguang, Zhou, Anwu, Evans, Matthew R, Posner, Bruce A, Roth, Michael G, Cobb, Melanie H

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High-throughput Screening for Potent and Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase von Baldwin, Jeffrey, Michnoff, Carolyn H., Malmquist, Nicholas A., White, John, Roth, Michael G., Rathod, Pradipsinh K., Phillips, Margaret A.

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Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor von Mata, Miguel A, Satterly, Neal, Versteeg, Gijs A, Frantz, Doug, Wei, Shuguang, Williams, Noelle, Schmolke, Mirco, Peña-Llopis, Samuel, Brugarolas, James, Forst, Christian V, White, Michael A, García-Sastre, Adolfo, Roth, Michael G, Fontoura, Beatriz M A

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Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export von Zhang, Liang, Das, Priyabrata, Schmolke, Mirco, Manicassamy, Balaji, Wang, Yaming, Deng, Xiaoyi, Cai, Ling, Tu, Benjamin P, Forst, Christian V, Roth, Michael G, Levy, David E, García-Sastre, Adolfo, de Brabander, Jef, Phillips, Margaret A, Fontoura, Beatriz M A

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Studies toward the Unique Pederin Family Member Psymberin: Structure–Activity Relationships, Biochemical Studies, and Genetics Identify the Mode-of-Action of Psymberin von Wu, Cheng-Yang, Feng, Yu, Cardenas, Eduardo R, Williams, Noelle, Floreancig, Paul E, De Brabander, Jef K, Roth, Michael G

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Host modulators of H1N1 cytopathogenicity von Ward, Samuel E, Kim, Hyun Seok, Komurov, Kakajan, Mendiratta, Saurabh, Tsai, Pei-Ling, Schmolke, Mirco, Satterly, Neal, Manicassamy, Balaji, Forst, Christian V, Roth, Michael G, García-Sastre, Adolfo, Blazewska, Katarzyna M, McKenna, Charles E, Fontoura, Beatriz M, White, Michael A

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Inhibition of iron uptake is responsible for differential sensitivity to V-ATPase inhibitors in several cancer cell lines von Straud, Sarah, Zubovych, Iryna, De Brabander, Jef K, Roth, Michael G

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Evaluating the potential of Vacuolar ATPase inhibitors as anticancer agents and multigram synthesis of the potent salicylihalamide analog saliphenylhalamide von Lebreton, Sylvain, Jaunbergs, Janis, Roth, Michael G., Ferguson, Deborah A., De Brabander, Jef K.

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