Necroptosis microenvironment directs lineage commitment in liver cancer von Seehawer, Marco, Heinzmann, Florian, D’Artista, Luana, Harbig, Jule, Roux, Pierre-François, Hoenicke, Lisa, Dang, Hien, Klotz, Sabrina, Robinson, Lucas, Doré, Grégory, Rozenblum, Nir, Kang, Tae-Won, Chawla, Rishabh, Buch, Thorsten, Vucur, Mihael, Roth, Mareike, Zuber, Johannes, Luedde, Tom, Sipos, Bence, Longerich, Thomas, Heikenwälder, Mathias, Wang, Xin Wei, Bischof, Oliver, Zender, Lars

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Transcriptional plasticity promotes primary and acquired resistance to BET inhibition von Rathert, Philipp, Roth, Mareike, Neumann, Tobias, Muerdter, Felix, Roe, Jae-Seok, Muhar, Matthias, Deswal, Sumit, Cerny-Reiterer, Sabine, Peter, Barbara, Jude, Julian, Hoffmann, Thomas, Boryń, Łukasz M., Axelsson, Elin, Schweifer, Norbert, Tontsch-Grunt, Ulrike, Dow, Lukas E., Gianni, Davide, Pearson, Mark, Valent, Peter, Stark, Alexander, Kraut, Norbert, Vakoc, Christopher R., Zuber, Johannes

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An Optimized microRNA Backbone for Effective Single-Copy RNAi von Fellmann, Christof, Hoffmann, Thomas, Sridhar, Vaishali, Hopfgartner, Barbara, Muhar, Matthias, Roth, Mareike, Lai, Dan Yu, Barbosa, Inês A.M., Kwon, Jung Shick, Guan, Yuanzhe, Sinha, Nishi, Zuber, Johannes

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Stage-specific control of early B cell development by the transcription factor Ikaros von Schwickert, Tanja A, Tagoh, Hiromi, Gültekin, Sinan, Dakic, Aleksandar, Axelsson, Elin, Minnich, Martina, Ebert, Anja, Werner, Barbara, Roth, Mareike, Cimmino, Luisa, Dickins, Ross A, Zuber, Johannes, Jaritz, Markus, Busslinger, Meinrad

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MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity von Skucha, Anna, Ebner, Jessica, Schmöllerl, Johannes, Roth, Mareike, Eder, Thomas, César-Razquin, Adrián, Stukalov, Alexey, Vittori, Sarah, Muhar, Matthias, Lu, Bin, Aichinger, Martin, Jude, Julian, Müller, André C., Győrffy, Balázs, Vakoc, Christopher R., Valent, Peter, Bennett, Keiryn L., Zuber, Johannes, Superti-Furga, Giulio, Grebien, Florian

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A kinase-independent role for CDK8 in BCR-ABL1+ leukemia von Menzl, Ingeborg, Zhang, Tinghu, Berger-Becvar, Angelika, Grausenburger, Reinhard, Heller, Gerwin, Prchal-Murphy, Michaela, Edlinger, Leo, Knab, Vanessa M., Uras, Iris Z., Grundschober, Eva, Bauer, Karin, Roth, Mareike, Skucha, Anna, Liu, Yao, Hatcher, John M., Liang, Yanke, Kwiatkowski, Nicholas P., Fux, Daniela, Hoelbl-Kovacic, Andrea, Kubicek, Stefan, Melo, Junia V., Valent, Peter, Weichhart, Thomas, Grebien, Florian, Zuber, Johannes, Gray, Nathanael S., Sexl, Veronika

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Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies von Matthews, Geoffrey M., Mehdipour, Parinaz, Cluse, Leonie A., Falkenberg, Katrina J., Wang, Eric, Roth, Mareike, Santoro, Fabio, Vidacs, Eva, Stanley, Kym, House, Colin M., Rusche, James R., Vakoc, Christopher R., Zuber, Johannes, Minucci, Saverio, Johnstone, Ricky W.

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X‐linked inhibitor of apoptosis protein represents a promising therapeutic target for relapsed/refractory ALL von Carlet, Michela, Schmelz, Karin, Vergalli, Jenny, Herold, Tobias, Senft, Daniela, Jurinovic, Vindi, Hoffmann, Thomas, Proba, Jutta, Weichert, Nina, Junghanß, Christian, Roth, Mareike, Eschenburg, Georg, Barz, Malwine, Henze, Günter, Eckert, Cornelia, Eggert, Angelika, Zuber, Johannes, Hundsdoerfer, Patrick, Jeremias, Irmela

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Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia von Rudolph, Dorothea, Impagnatiello, Maria Antonietta, Blaukopf, Claudia, Sommer, Christoph, Gerlich, Daniel W, Roth, Mareike, Tontsch-Grunt, Ulrike, Wernitznig, Andreas, Savarese, Fabio, Hofmann, Marco H, Albrecht, Christoph, Geiselmann, Lena, Reschke, Markus, Garin-Chesa, Pilar, Zuber, Johannes, Moll, Jürgen, Adolf, Günther R, Kraut, Norbert

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Is It Worth It? Obesity Affects Snack Food Valuation Across the Menstrual Cycle von Heuberger, Larissa S, Gobbi, Susanna, Weber, Susanna C, Graf, Gwendolyn, Tobler, Philippe N, Asarian, Lori, Geary, Nori, Roth, Mareike, Leeners, Brigitte

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lncRNA requirements for mouse acute myeloid leukemia and normal differentiation von Delás, M Joaquina, Sabin, Leah R, Dolzhenko, Egor, Knott, Simon Rv, Munera Maravilla, Ester, Jackson, Benjamin T, Wild, Sophia A, Kovacevic, Tatjana, Stork, Eva Maria, Zhou, Meng, Erard, Nicolas, Lee, Emily, Kelley, David R, Roth, Mareike, Barbosa, Inês Am, Zuber, Johannes, Rinn, John L, Smith, Andrew D, Hannon, Gregory J

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A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation von Pinter, Sabine, Knodel, Franziska, Choudalakis, Michel, Schnee, Philipp, Kroll, Carolin, Fuchs, Marina, Broehm, Alexander, Weirich, Sara, Roth, Mareike, Eisler, Stephan A, Zuber, Johannes, Jeltsch, Albert, Rathert, Philipp

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Molecular role of the PAX5‐ETV6 oncoprotein in promoting B‐cell acute lymphoblastic leukemia von Smeenk, Leonie, Fischer, Maria, Jurado, Sabine, Jaritz, Markus, Azaryan, Anna, Werner, Barbara, Roth, Mareike, Zuber, Johannes, Stanulla, Martin, den Boer, Monique L, Mullighan, Charles G, Strehl, Sabine, Busslinger, Meinrad

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MEK1 is required for the development of NRAS-driven leukemia von Nowacka, Joanna D, Baumgartner, Christian, Pelorosso, Cristiana, Roth, Mareike, Zuber, Johannes, Baccarini, Manuela

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Novel genetically engineered patient-derived xenograft (GEPDX) models reveal that XIAP plays an essential role for patients’ all growing in mice von Vergalli, Jenny, Carlet, Michela, Hoffmann, Thomas, Roth, Mareike, Zuber, Johannes, Jeremias, Irmela

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Author Correction: Necroptosis microenvironment directs lineage commitment in liver cancer von Seehawer, Marco, Heinzmann, Florian, D’Artista, Luana, Harbig, Jule, Roux, Pierre-François, Hoenicke, Lisa, Dang, Hien, Klotz, Sabrina, Robinson, Lucas, Doré, Grégory, Rozenblum, Nir, Kang, Tae-Won, Chawla, Rishabh, Buch, Thorsten, Vucur, Mihael, Roth, Mareike, Zuber, Johannes, Luedde, Tom, Sipos, Bence, Longerich, Thomas, Heikenwälder, Mathias, Wang, Xin Wei, Bischof, Oliver, Zender, Lars

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Necroptosis microenvironment directs lineage commitment in liver cancer von Seehawer, Marco, Heinzmann, Florian, D’Artista, Luana, Harbig, Jule, Roux, Pierre-François, Hoenicke, Lisa, Dang, Hien, Klotz, Sabrina, Robinson, Lucas, Doré, Grégory, Rozenblum, Nir, Kang, Tae-Won, Chawla, Rishabh, Buch, Thorsten, Vucur, Mihael, Roth, Mareike, Zuber, Johannes, Luedde, Tom, Sipos, Bence, Longerich, Thomas, Heikenwälder, Mathias, Wang, Xin Wei, Bischof, Oliver, Zender, Lars

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Is It Worth It? Obesity Affects Snack Food Valuation Across the Menstrual Cycle von Heuberger, Larissa S, Gobbi, Susanna, Weber, Susanna C, Graf, Gwendolyn, Tobler, Philippe N, Asarian, Lori, Geary, Nori, Roth, Mareike, Leeners, Brigitte

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Molecular role of the PAX 5‐ ETV 6 oncoprotein in promoting B‐cell acute lymphoblastic leukemia von Smeenk, Leonie, Fischer, Maria, Jurado, Sabine, Jaritz, Markus, Azaryan, Anna, Werner, Barbara, Roth, Mareike, Zuber, Johannes, Stanulla, Martin, den Boer, Monique L, Mullighan, Charles G, Strehl, Sabine, Busslinger, Meinrad

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Abstract 5533: RNAi-mediated depletion of histone deacetylases highlights the potential for isoform-specific inhibitors in B-cell lymphoma and acute myeloid leukemia von Matthews, Geoffrey M., Cluse, Leonie, Wang, Eric, Roth, Mareike, Vakoc, Chris, Miao, Wenyan, Rusche, James, Zuber, Johannes, Johnstone, Ricky W.

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