Population Pharmacokinetics and Pharmacodynamics of Benralizumab in Healthy Volunteers and Patients With Asthma von Wang, B, Yan, L, Yao, Z, Roskos, LK

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Clinical Pharmacology: a Discipline at the Nexus Between Translational Science and Precision Medicine: Commentary on “Enhancing Value of Clinical Pharmacodynamics in Oncology Drug... von Vicini, P, Roskos, LK

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Topiramate and Phenytoin Pharmacokinetics During Repetitive Monotherapy and Combination Therapy to Epileptic Patients von Sachdeo, R. C., Sachdeo, S. K., Levy, R. H., Streeter, A. J., Bishop, F. E., Kunze, K. L., Mather, G. G., Roskos, L. K., Shen, D. D., Thummel, K. E., Trager, W. F., Curtin, C. R., Doose, Dennis R., Gisclon, L. G., Bialer, Meir

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Elimination mechanisms of therapeutic monoclonal antibodies von Tabrizi, Mohammad A., Tseng, Chih-Ming L., Roskos, Lorin K.

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Preclinical and clinical safety of monoclonal antibodies von Tabrizi, Mohammad A., Roskos, Lorin K.

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Effects of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers von Harker, Laurence A., Roskos, Lorin K., Marzec, Ulla M., Carter, Richard A., Cherry, Judith K., Sundell, Birgitta, Cheung, Ellen N., Terry, Dixon, Sheridan, William

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Population pharmacokinetic-pharmacodynamic modeling of filgrastim (r-metHuG-CSF) in healthy volunteers von Wang, B, Ludden, T M, Cheung, E N, Schwab, G G, Roskos, L K

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Treatment of steroid-refractory acute graft-versus-host disease with anti-CD147 monoclonal antibody ABX-CBL von Deeg, H. Joachim, Blazar, Bruce R., Bolwell, Brian J., Long, Gwynn D., Schuening, Friedrich, Cunningham, John, Rifkin, Robert M., Abhyankar, Sunil, Briggs, Adrienne D., Burt, Richard, Lipani, John, Roskos, Lorin K., White, J. Michael, Havrilla, Nancy, Schwab, Gisela, Heslop, Helen E.

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The clinical pharmacology of therapeutic monoclonal antibodies von Roskos, Lorin K., Davis, C. Geoffrey, Schwab, Gisela M.

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A population approach to enzyme characterization and identification : Application to phenacetin O-deethylation von BELLE, Donna J, RING, Barbara J, ALLERHEILIGEN, Sandra R. B, HEATHMAN, Michael A, O'BRIEN, Lisa M, SINHA, Vikram, ROSKOS, Lorin K, WRIGHTON, Steven A

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Cyclic immune thrombocytopenia responsive to thrombopoietic growth factor therapy von Rice, Lawrence, Nichol, Janet L., McMillan, Robert, Roskos, Lorin K., Bacile, Margaret

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Pharmacokinetic Analysis of Pegylated Megakaryocyte Growth and Development Factor in Humans von De Boer, Richard H., Roskos, Lorin K., Cheung, Ellen, Fox, Simon, Basser, Russell L., Marty, Jennifer, Begley, C. Glenn, Cebon, Jonathan

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Suppression of soluble T cell-associated proteins by an anti-interferon-  monoclonal antibody in adult patients with dermatomyositis or polymyositis von Guo, X., Higgs, B. W., Rebelatto, M., Zhu, W., Greth, W., Yao, Y., Roskos, L. K., White, W. I.

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Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody von Foon, Kenneth A, Yang, Xiao-Dong, Weiner, Louis M, Belldegrun, Arie S, Figlin, Robert A, Crawford, Jeffrey, Rowinsky, Eric K, Dutcher, Janice P, Vogelzang, Nicholas J, Gollub, Jared, Thompson, John A, Schwartz, Garry, Bukowski, Ronald M, Roskos, Lorin K, Schwab, Gisela M

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AB0445 Exposure–Efficacy Analysis of Mavrilimumab in Rheumatoid Arthritis: Modeling and Simulation of Phase II Clinical Data von Jin, D.C., Wu, C.-Y., Roskos, L.K., Godwood, A., Close, D., Wang, B.

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OP0244 Sustained Suppression of Rheumatoid Arthritis Disease Markers by Mavrilimumab but Not Golimumab in Anti-Tumor Necrosis Factor-Inadequate Responders: An Exploratory Analysis... von Guo, X., Wang, S., Bay-Jensen, A.C., Karsdal, M.A., Godwood, A., Close, D., Ryan, P.C., Roskos, L.K., White, W.I.

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SAT0212 Sustained Response to Mavrilimumab in Rheumatoid Arthritis Patients VIA Suppression of Macrophage and T Cells von Guo, X., Sinibaldi, D., Kuziora, M., Brohawn, P., Ryan, P.C., Bay-Jensen, A.C., Karsdal, M.A., Roskos, L.K., White, W.I.

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OP0238 Suppression of T Cell Activation and Collagen Accumulation by an Anti-Type I Interferon Receptor Monoclonal Antibody in Adult Subjects with Systemic Sclerosis von Guo, X., Higgs, B.W., Bay-Jensen, A.-C., Morehouse, C., Liu, Z., Wang, L., Yoo, S., Karsdal, M.A., Yao, Y., Roskos, L.K., White, W.I.

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Polyethylene Glycol Modification of Filgrastim Results in Decreased Renal Clearance of the Protein in Rats von Yang, Bing-Bing, Lum, Peggy K., Hayashi, Michael M., Roskos, Lorin K.

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Integration of pharmacokinetic and pharmacodynamic studies in the discovery, development, and review of protein therapeutic agents: A conference report von Galluppi, Gerald R., Rogge, Mark C., Roskos, Lorin K., Lesko, Lawrence J., Green, Martin D., Feigal, David W., Peck, Carl C.

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