Pharmacogenetics in drug discovery and development: a translational perspective von Roses, Allen D

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Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study von Lin, X, Song, K, Lim, N, Yuan, X, Johnson, T, Abderrahmani, A, Vollenweider, P, Stirnadel, H, Sundseth, S. S, Lai, E, Burns, D. K, Middleton, L. T, Roses, A. D, Matthews, P. M, Waeber, G, Cardon, L, Waterworth, D. M, Mooser, V

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APOLIPOPROTEIN E ALLELES AS RISK FACTORS IN ALZHEIMER'S DISEASE von Roses, M.D, Allen D

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Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts von Muglia, P, Tozzi, F, Galwey, N W, Francks, C, Upmanyu, R, Kong, X Q, Antoniades, A, Domenici, E, Perry, J, Rothen, S, Vandeleur, C L, Mooser, V, Waeber, G, Vollenweider, P, Preisig, M, Lucae, S, Müller-Myhsok, B, Holsboer, F, Middleton, L T, Roses, A D

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A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing von Davies, G, Harris, S E, Reynolds, C A, Payton, A, Knight, H M, Liewald, D C, Lopez, L M, Luciano, M, Gow, A J, Corley, J, Henderson, R, Murray, C, Pattie, A, Fox, H C, Redmond, P, Lutz, M W, Chiba-Falek, O, Linnertz, C, Saith, S, Haggarty, P, McNeill, G, Ke, X, Ollier, W, Horan, M, Roses, A D, Ponting, C P, Porteous, D J, Tenesa, A, Pickles, A, Starr, J M, Whalley, L J, Pedersen, N L, Pendleton, N, Visscher, P M, Deary, I J

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Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry von Scott, Laura J, Muglia, Pierandrea, Kong, Xiangyang Q, Guan, Weihua, Flickinger, Matthew, Upmanyu, Ruchi, Tozzi, Federica, Li, Jun Z, Burmeister, Margit, Absher, Devin, Thompson, Robert C, Francks, Clyde, Meng, Fan, Antoniades, Athos, Southwick, Audrey M, Schatzberg, Alan F, Bunney, William E, Barchas, Jack D, Jones, Edward G, Day, Richard, Matthews, Keith, McGuffin, Peter, Strauss, John S, Kennedy, James L, Middleton, Lefkos, Roses, Allen D, Watson, Stanley J, Vincent, John B, Myers, Richard M, Farmer, Ann E, Akil, Huda, Burns, Daniel K, Boehnke, Michael

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Pharmacogenetics and future drug development and delivery von Roses, Allen D

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Genetic variations in HLA-B region and hypersensitivity reactions to abacavir von Hetherington, Seth, Hughes, Arlene R, Mosteller, Michael, Shortino, Denise, Baker, Katherine L, Spreen, William, Lai, Eric, Davies, Kirstie, Handley, Abigail, Dow, David J, Fling, Mary E, Stocum, Michael, Bowman, Clive, Thurmond, Linda M, Roses, Allen D

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Using Genetics to Enable Studies on the Prevention of Alzheimer's Disease von Crenshaw, D G, Gottschalk, W K, Lutz, M W, Grossman, I, Saunders, A M, Burke, J R, Welsh-Bohmer, K A, Brannan, S K, Burns, D K, Roses, A D

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Genome-based pharmacogenetics and the pharmaceutical industry von Roses, Allen D

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Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease von Risner, M E, Saunders, A M, Altman, J F B, Ormandy, G C, Craft, S, Foley, I M, Zvartau-Hind, M E, Hosford, D A, Roses, A D

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New applications of disease genetics and pharmacogenetics to drug development von Roses, Allen D, Saunders, Ann M, Lutz, Michael W, Zhang, Nanyin, Hariri, Ahmad R, Asin, Karen E, Crenshaw, Donna G, Budur, Kumar, Burns, Daniel K, Brannan, Stephen K

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The genetic contributions of SNCA and LRRK2 genes to Lewy Body pathology in Alzheimer's disease von Linnertz, Colton, Lutz, Michael W, Ervin, John F, Allen, Jawara, Miller, Natalie R, Welsh-Bohmer, Kathleen A, Roses, Allen D, Chiba-Falek, Ornit

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Cerebral Metabolic and Cognitive Decline in Persons at Genetic Risk for Alzheimer's Disease von Small, Gary W., Ercoli, Linda M., Daniel H. S. Silverman, S.-C. Huang, Komo, Scott, Bookheimer, Susan Y., Lavretsky, Helen, Miller, Karen, Siddarth, Prabha, Rasgon, Natalie L., Mazziotta, John C., Saxena, Sanjaya, Wu, H. M., Mega, Michael S., Cummings, Jeffrey L., Saunders, Ann M., Pericak-Vance, Margaret A., Roses, Allen D., Barrio, Jorge R., Phelps, Michael E.

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Apolipoprotein E Affects the Rate of Alzheimer Disease Expression: (β-Amyloid Burden Is a Secondary Consequence Dependent on APOE Genotype and Duration of Disease von Roses, Allen D

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Apolipoprotein E and Alzheimer Disease von Strittmatter, Warren J., Roses, Allen D.

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Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease) von Roses, A D, Saunders, A M, Huang, Y, Strum, J, Weisgraber, K H, Mahley, R W

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Binding of Human Apolipoprotein E to Synthetic Amyloid β Peptide: Isoform-Specific Effects and Implications for Late-Onset Alzheimer Disease von Strittmatter, Warren J., Weisgraber, Karl H., Huang, David Y., Dong, Li-Ming, Salvesen, Guy S., Pericak-Vance, Margaret, Schmechel, Donald, Saunders, Ann M., Goldgaber, Dmitry, Roses, Allen D.

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Apolipoprotein E: High-Avidity Binding to β-Amyloid and Increased Frequency of Type 4 Allele in Late-Onset Familial Alzheimer Disease von Strittmatter, Warren J., Saunders, Ann M., Schmechel, Donald, Pericak-Vance, Margaret, Enghild, Jan, Salvesen, Guy S., Roses, Allen D.

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APOE ε4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans von Yu, Lei, Lutz, Michael W, Wilson, Robert S, Burns, Daniel K, Roses, Allen D, Saunders, Ann M, Yang, Jingyun, Gaiteri, Chris, De Jager, Philip L, Barnes, Lisa L, Bennett, David A

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