Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes von Zhu, Zengrong, Li, Qing V., Lee, Kihyun, Rosen, Bess P., González, Federico, Soh, Chew-Li, Huangfu, Danwei

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Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions von Luo, Renhe, Yan, Jielin, Oh, Jin Woo, Xi, Wang, Shigaki, Dustin, Wong, Wilfred, Cho, Hyein S., Murphy, Dylan, Cutler, Ronald, Rosen, Bess P., Pulecio, Julian, Yang, Dapeng, Glenn, Rachel A., Chen, Tingxu, Li, Qing V., Vierbuchen, Thomas, Sidoli, Simone, Apostolou, Effie, Huangfu, Danwei, Beer, Michael A.

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Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness von Rosen, Bess P., Li, Qing V., Cho, Hyein S., Liu, Dingyu, Yang, Dapeng, Graff, Sarah, Yan, Jielin, Luo, Renhe, Verma, Nipun, Damodaran, Jeyaram R., Kale, Hanuman T., Kaplan, Samuel J., Beer, Michael A., Sidoli, Simone, Huangfu, Danwei

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QSER1 protects DNA methylation valleys from de novo methylation von Dixon, Gary, Pan, Heng, Yang, Dapeng, Rosen, Bess P, Jashari, Therande, Verma, Nipun, Pulecio, Julian, Caspi, Inbal, Lee, Kihyun, Stransky, Stephanie, Glezer, Abigail, Liu, Chang, Rivas, Marco, Kumar, Ritu, Lan, Yahui, Torregroza, Ingrid, He, Chuan, Sidoli, Simone, Evans, Todd, Elemento, Olivier, Huangfu, Danwei

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Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation von Li, Qing V., Dixon, Gary, Verma, Nipun, Rosen, Bess P., Gordillo, Miriam, Luo, Renhe, Xu, Chunlong, Wang, Qiong, Soh, Chew-Li, Yang, Dapeng, Crespo, Miguel, Shukla, Abhijit, Xiang, Qing, Dündar, Friederike, Zumbo, Paul, Witkin, Matthew, Koche, Richard, Betel, Doron, Chen, Shuibing, Massagué, Joan, Garippa, Ralph, Evans, Todd, Beer, Michael A., Huangfu, Danwei

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Glutamine independence is a selectable feature of pluripotent stem cells von Vardhana, Santosha A., Arnold, Paige K., Rosen, Bess P., Chen, Yanyang, Carey, Bryce W., Huangfu, Danwei, Carmona-Fontaine, Carlos, Thompson, Craig B., Finley, Lydia W. S.

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Decoding pluripotency: Genetic screens to interrogate the acquisition, maintenance, and exit of pluripotency von Li, Qing V., Rosen, Bess P., Huangfu, Danwei

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CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction von Yang, Dapeng, Cho, Hyunwoo, Tayyebi, Zakieh, Shukla, Abhijit, Luo, Renhe, Dixon, Gary, Ursu, Valeria, Stransky, Stephanie, Tremmel, Daniel M., Sackett, Sara D., Koche, Richard, Kaplan, Samuel J., Li, Qing V., Park, Jiwoon, Zhu, Zengrong, Rosen, Bess P., Pulecio, Julian, Shi, Zhong-Dong, Bram, Yaron, Schwartz, Robert E., Odorico, Jon S., Sidoli, Simone, Wright, Christopher V., Leslie, Christina S., Huangfu, Danwei

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Glutamine independence is a selectable feature of pluripotent stem cells von Vardhana, Santosha A., Arnold, Paige K., Rosen, Bess P., Chen, Yanyang, Carey, Bryce W., Huangfu, Danwei, Carmona-Fontaine, Carlos, Thompson, Craig B., Finley, Lydia W. S.

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Dynamic-network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer-gene regulatory activity during cell state transitions von Luo, Renhe, Yan, Jielin, Oh, Jin Woo, Xi, Wang, Shigaki, Dustin, Wong, Wilfred, Cho, Hyunwoo, Murphy, Dylan, Cutler, Ronald, Rosen, Bess P., Pulecio, Julian, Yang, Dapeng, Glenn, Rachel, Vierbuchen, Thomas, Sidoli, Simone, Apostolou, Effie, Huangfu, Danwei

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MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling von Mellios, N, Feldman, D A, Sheridan, S D, Ip, J P K, Kwok, S, Amoah, S K, Rosen, B, Rodriguez, B A, Crawford, B, Swaminathan, R, Chou, S, Li, Y, Ziats, M, Ernst, C, Jaenisch, R, Haggarty, S J, Sur, M

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Precise interpolar phasing of abrupt climate change during the last ice age von Buizert, Christo, Adrian, Betty, Ahn, Jinho, Albert, Mary, Alley, Richard B, Baggenstos, Daniel, Bauska, Thomas K, Bay, Ryan C, Bencivengo, Brian B, Bentley, Charles R, Brook, Edward J, Chellman, Nathan J, Clow, Gary D, Cole-Dai, Jihong, Conway, Howard, Cravens, Eric, Cuffey, Kurt M, Dunbar, Nelia W, Edwards, Jon S, Fegyveresi, John M, Ferris, Dave G, Fitzpatrick, Joan J, Fudge, T J, Gibson, Chris J, Gkinis, Vasileios, Goetz, Joshua J, Gregory, Stephanie, Hargreaves, Geoffrey M, Iverson, Nels, Johnson, Jay A, Jones, Tyler R, Kalk, Michael L, Kippenhan, Matthew J, Koffman, Bess G, Kreutz, Karl, Kuhl, Tanner W, Lebar, Donald A, Lee, James E, Marcott, Shaun A, Markle, Bradley R, Maselli, Olivia J, McConnell, Joseph R, McGwire, Kenneth C, Mitchell, Logan E, Mortensen, Nicolai B, Neff, Peter D, Nishiizumi, Kunihiko, Nunn, Richard M, Orsi, Anais J, Pasteris, Daniel R, Pedro, Joel B, Pettit, Erin C, Price, P Buford, Priscu, John C, Rhodes, Rachael H, Rosen, Julia L, Schauer, Andrew J, Schoenemann, Spruce W, Sendelbach, Paul J, Severinghaus, Jeffrey P, Shturmakov, Alexander J, Sigl, Michael, Slawny, Kristina R, Souney, Joseph M, Sowers, Todd A, Spencer, Matthew K, Steig, Eric J, Taylor, Kendrick C, Twickler, Mark S, Vaughn, Bruce H, Voigt, Donald E, Waddington, Edwin D, Welten, Kees C, Wendricks, Anthony W, White, James W C, Winstrup, Mai, Wong, Gifford J, Woodruff, Thomas E

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Baseline Characteristics of the Vitamin D and Type 2 Diabetes (D2d) Study: A Contemporary Prediabetes Cohort That Will Inform Diabetes Prevention Efforts von LeBlanc, Erin S, Pratley, Richard E, Dawson-Hughes, Bess, Staten, Myrlene A, Sheehan, Patricia R, Lewis, Michael R, Peters, Anne, Kim, Sun H, Chatterjee, Ranee, Aroda, Vanita R, Chadha, Chhavi, Neff, Lisa M, Brodsky, Irwin G, Rosen, Clifford, Desouza, Cyrus V, Foreyt, John P, Hsia, Daniel S, Johnson, Karen C, Raskin, Philip, Kashyap, Sangeeta R, O'Neil, Patrick, Phillips, Lawrence S, Rasouli, Neda, Liao, Emilia P, Robbins, David C, Pittas, Anastassios G

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Erratum. Baseline Characteristics of the Vitamin D and Type 2 Diabetes (D2d) Study: A Contemporary Prediabetes Cohort That Will Inform Diabetes Prevention Efforts. Diabetes Care 20... von LeBlanc, Erin S., Pratley, Richard E., Dawson-Hughes, Bess, Staten, Myrlene A., Sheehan, Patricia R., Lewis, Michael R., Peters, Anne, Kim, Sun H., Chatterjee, Ranee, Aroda, Vanita R., Chadha, Chhavi, Neff, Lisa M., Brodsky, Irwin G., Rosen, Clifford, Desouza, Cyrus V., Foreyt, John P., Hsia, Daniel S., Johnson, Karen C., Raskin, Philip, Kashyap, Sangeeta R., O’Neil, Patrick, Phillips, Lawrence S., Rasouli, Neda, Liao, Emilia P., Robbins, David C., Pittas, Anastassios G.

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Vitamin D Dose Requirements for Fracture Prevention von Ott, Susan M, Grey, Andrew, Bolland, Mark J, Reid, Ian R, Rosen, Clifford J, Mayne, Susan T, Paterson, Colin R, Bischoff-Ferrari, Heike A, Willett, Walter C, Dawson-Hughes, Bess, Heaney, Robert P

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Dietary Changes Favorably Affect Bone Remodeling in Older Adults von HEANEY, ROBERT P., McCARRON, DAVID A., DAWSON-HUGHES, BESS, OPARIL, SUZANNE, BERGA, SARAH L., STERN, JUDITH S., BARR, SUSAN I., ROSEN, CLIFFORD J.

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