Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes von Zhu, Zengrong, Li, Qing V., Lee, Kihyun, Rosen, Bess P., González, Federico, Soh, Chew-Li, Huangfu, Danwei

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Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions von Luo, Renhe, Yan, Jielin, Oh, Jin Woo, Xi, Wang, Shigaki, Dustin, Wong, Wilfred, Cho, Hyein S., Murphy, Dylan, Cutler, Ronald, Rosen, Bess P., Pulecio, Julian, Yang, Dapeng, Glenn, Rachel A., Chen, Tingxu, Li, Qing V., Vierbuchen, Thomas, Sidoli, Simone, Apostolou, Effie, Huangfu, Danwei, Beer, Michael A.

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QSER1 protects DNA methylation valleys from de novo methylation von Dixon, Gary, Pan, Heng, Yang, Dapeng, Rosen, Bess P, Jashari, Therande, Verma, Nipun, Pulecio, Julian, Caspi, Inbal, Lee, Kihyun, Stransky, Stephanie, Glezer, Abigail, Liu, Chang, Rivas, Marco, Kumar, Ritu, Lan, Yahui, Torregroza, Ingrid, He, Chuan, Sidoli, Simone, Evans, Todd, Elemento, Olivier, Huangfu, Danwei

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Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation von Li, Qing V., Dixon, Gary, Verma, Nipun, Rosen, Bess P., Gordillo, Miriam, Luo, Renhe, Xu, Chunlong, Wang, Qiong, Soh, Chew-Li, Yang, Dapeng, Crespo, Miguel, Shukla, Abhijit, Xiang, Qing, Dündar, Friederike, Zumbo, Paul, Witkin, Matthew, Koche, Richard, Betel, Doron, Chen, Shuibing, Massagué, Joan, Garippa, Ralph, Evans, Todd, Beer, Michael A., Huangfu, Danwei

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Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness von Rosen, Bess P., Li, Qing V., Cho, Hyein S., Liu, Dingyu, Yang, Dapeng, Graff, Sarah, Yan, Jielin, Luo, Renhe, Verma, Nipun, Damodaran, Jeyaram R., Kale, Hanuman T., Kaplan, Samuel J., Beer, Michael A., Sidoli, Simone, Huangfu, Danwei

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Decoding pluripotency: Genetic screens to interrogate the acquisition, maintenance, and exit of pluripotency von Li, Qing V., Rosen, Bess P., Huangfu, Danwei

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CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction von Yang, Dapeng, Cho, Hyunwoo, Tayyebi, Zakieh, Shukla, Abhijit, Luo, Renhe, Dixon, Gary, Ursu, Valeria, Stransky, Stephanie, Tremmel, Daniel M., Sackett, Sara D., Koche, Richard, Kaplan, Samuel J., Li, Qing V., Park, Jiwoon, Zhu, Zengrong, Rosen, Bess P., Pulecio, Julian, Shi, Zhong-Dong, Bram, Yaron, Schwartz, Robert E., Odorico, Jon S., Sidoli, Simone, Wright, Christopher V., Leslie, Christina S., Huangfu, Danwei

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Glutamine independence is a selectable feature of pluripotent stem cells von Vardhana, Santosha A., Arnold, Paige K., Rosen, Bess P., Chen, Yanyang, Carey, Bryce W., Huangfu, Danwei, Carmona-Fontaine, Carlos, Thompson, Craig B., Finley, Lydia W. S.

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Glutamine independence is a selectable feature of pluripotent stem cells von Vardhana, Santosha A., Arnold, Paige K., Rosen, Bess P., Chen, Yanyang, Carey, Bryce W., Huangfu, Danwei, Carmona-Fontaine, Carlos, Thompson, Craig B., Finley, Lydia W. S.

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MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling von Mellios, N, Feldman, D A, Sheridan, S D, Ip, J P K, Kwok, S, Amoah, S K, Rosen, B, Rodriguez, B A, Crawford, B, Swaminathan, R, Chou, S, Li, Y, Ziats, M, Ernst, C, Jaenisch, R, Haggarty, S J, Sur, M

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Sphingosine Kinase 1 Is Regulated by Peroxisome Proliferator-activated Receptor α in Response to Free Fatty Acids and Is Essential for Skeletal Muscle Interleukin-6 Production and... von Ross, Jessica S., Hu, Wei, Rosen, Bess, Snider, Ashley J., Obeid, Lina M., Cowart, L. Ashley

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Sphingosine Kinase 1 is regulated by PPARα in response to free fatty acids and mediates skeletal muscle IL‐6 production and signaling in diet‐induced obesity von Ross, Jessica Shavonne, Hu, Wei, Rosen, Bess, Snider, Ashley J, Obeid, Lina M, Cowart, L. Ashley

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Dynamic-network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer-gene regulatory activity during cell state transitions von Luo, Renhe, Yan, Jielin, Oh, Jin Woo, Xi, Wang, Shigaki, Dustin, Wong, Wilfred, Cho, Hyunwoo, Murphy, Dylan, Cutler, Ronald, Rosen, Bess P., Pulecio, Julian, Yang, Dapeng, Glenn, Rachel, Vierbuchen, Thomas, Sidoli, Simone, Apostolou, Effie, Huangfu, Danwei

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MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling von Mellios, Nikolaos, Feldman, Danielle A, Sheridan, Steven D, Ip, Jacque P.K, Kwok, Showming, Amoah, Stephen K, Rosen, Bess, Rodriguez, Brian A, Crawford, Benjamin, Swaminathan, Radha, Chou, Stephanie, Li, Yun, Ziats, Mark, Ernst, Carl, Jaenisch, Rudolf, Haggarty, Stephen J, Sur, Mriganka

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Precise interpolar phasing of abrupt climate change during the last ice age von Buizert, Christo, Adrian, Betty, Ahn, Jinho, Albert, Mary, Alley, Richard B, Baggenstos, Daniel, Bauska, Thomas K, Bay, Ryan C, Bencivengo, Brian B, Bentley, Charles R, Brook, Edward J, Chellman, Nathan J, Clow, Gary D, Cole-Dai, Jihong, Conway, Howard, Cravens, Eric, Cuffey, Kurt M, Dunbar, Nelia W, Edwards, Jon S, Fegyveresi, John M, Ferris, Dave G, Fitzpatrick, Joan J, Fudge, T J, Gibson, Chris J, Gkinis, Vasileios, Goetz, Joshua J, Gregory, Stephanie, Hargreaves, Geoffrey M, Iverson, Nels, Johnson, Jay A, Jones, Tyler R, Kalk, Michael L, Kippenhan, Matthew J, Koffman, Bess G, Kreutz, Karl, Kuhl, Tanner W, Lebar, Donald A, Lee, James E, Marcott, Shaun A, Markle, Bradley R, Maselli, Olivia J, McConnell, Joseph R, McGwire, Kenneth C, Mitchell, Logan E, Mortensen, Nicolai B, Neff, Peter D, Nishiizumi, Kunihiko, Nunn, Richard M, Orsi, Anais J, Pasteris, Daniel R, Pedro, Joel B, Pettit, Erin C, Price, P Buford, Priscu, John C, Rhodes, Rachael H, Rosen, Julia L, Schauer, Andrew J, Schoenemann, Spruce W, Sendelbach, Paul J, Severinghaus, Jeffrey P, Shturmakov, Alexander J, Sigl, Michael, Slawny, Kristina R, Souney, Joseph M, Sowers, Todd A, Spencer, Matthew K, Steig, Eric J, Taylor, Kendrick C, Twickler, Mark S, Vaughn, Bruce H, Voigt, Donald E, Waddington, Edwin D, Welten, Kees C, Wendricks, Anthony W, White, James W C, Winstrup, Mai, Wong, Gifford J, Woodruff, Thomas E

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Vitamin D Supplementation and Prevention of Type 2 Diabetes von Pittas, Anastassios G, Dawson-Hughes, Bess, Sheehan, Patricia, Ware, James H, Knowler, William C, Aroda, Vanita R, Brodsky, Irwin, Ceglia, Lisa, Chadha, Chhavi, Chatterjee, Ranee, Desouza, Cyrus, Dolor, Rowena, Foreyt, John, Fuss, Paul, Ghazi, Adline, Hsia, Daniel S, Johnson, Karen C, Kashyap, Sangeeta R, Kim, Sun, LeBlanc, Erin S, Lewis, Michael R, Liao, Emilia, Neff, Lisa M, Nelson, Jason, O’Neil, Patrick, Park, Jean, Peters, Anne, Phillips, Lawrence S, Pratley, Richard, Raskin, Philip, Rasouli, Neda, Robbins, David, Rosen, Clifford, Vickery, Ellen M, Staten, Myrlene

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Yoga as a Complementary Therapy for Smoking Cessation: Results From BreathEasy, a Randomized Clinical Trial von Bock, Beth C, Dunsiger, Shira I, Rosen, Rochelle K, Thind, Herpreet, Jennings, Ernestine, Fava, Joseph L, Becker, Bruce M, Carmody, James, Marcus, Bess H

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Internet-Based Physical Activity Intervention for Women With a Family History of Breast Cancer von Hartman, Sheri J, Dunsiger, Shira I, Marinac, Catherine R, Marcus, Bess H, Rosen, Rochelle K, Gans, Kim M

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Effects of Vitamin D Supplementation on Insulin Sensitivity and Secretion in Prediabetes von Rasouli, Neda, Brodsky, Irwin G, Chatterjee, Ranee, Kim, Sun H, Pratley, Richard E, Staten, Myrlene A, Pittas, Anastassios G

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Rationale and design of the Vitamin D and Type 2 Diabetes (D2d) study: a diabetes prevention trial von Pittas, Anastassios G, Dawson-Hughes, Bess, Sheehan, Patricia R, Rosen, Clifford J, Ware, James H, Knowler, William C, Staten, Myrlene A

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