T cell costimulation blockade blunts pressure overload-induced heart failure von Kallikourdis, Marinos, Martini, Elisa, Carullo, Pierluigi, Sardi, Claudia, Roselli, Giuliana, Greco, Carolina M., Vignali, Debora, Riva, Federica, Ormbostad Berre, Anne Marie, Stølen, Tomas O., Fumero, Andrea, Faggian, Giuseppe, Di Pasquale, Elisa, Elia, Leonardo, Rumio, Cristiano, Catalucci, Daniele, Papait, Roberto, Condorelli, Gianluigi

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Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation von Choi, Seung Hoan, Weng, Lu-Chen, Roselli, Carolina, Lin, Honghuang, Haggerty, Christopher M, Shoemaker, M. Benjamin, Barnard, John, Arking, Dan E, Chasman, Daniel I, Albert, Christine M, Chaffin, Mark, Tucker, Nathan R, Smith, Jonathan D, Gupta, Namrata, Gabriel, Stacey, Margolin, Lauren, Shea, Marisa A, Shaffer, Christian M, Yoneda, Zachary T, Boerwinkle, Eric, Smith, Nicholas L, Silverman, Edwin K, Redline, Susan, Vasan, Ramachandran S, Burchard, Esteban G, Gogarten, Stephanie M, Laurie, Cecelia, Blackwell, Thomas W, Abecasis, Gonçalo, Carey, David J, Fornwalt, Brandon K, Smelser, Diane T, Baras, Aris, Dewey, Frederick E, Jaquish, Cashell E, Papanicolaou, George J, Sotoodehnia, Nona, Van Wagoner, David R, Psaty, Bruce M, Kathiresan, Sekar, Darbar, Dawood, Alonso, Alvaro, Heckbert, Susan R, Chung, Mina K, Roden, Dan M, Benjamin, Emelia J, Murray, Michael F, Lunetta, Kathryn L, Lubitz, Steven A, Ellinor, Patrick T

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Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank von Jurgens, Sean J., Choi, Seung Hoan, Morrill, Valerie N., Chaffin, Mark, Pirruccello, James P., Halford, Jennifer L., Weng, Lu-Chen, Nauffal, Victor, Roselli, Carolina, Hall, Amelia W., Oetjens, Matthew T., Lagerman, Braxton, vanMaanen, David P., Aragam, Krishna G., Lunetta, Kathryn L., Haggerty, Christopher M., Lubitz, Steven A., Ellinor, Patrick T.

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Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations von Khera, Amit V., Chaffin, Mark, Aragam, Krishna G., Haas, Mary E., Roselli, Carolina, Choi, Seung Hoan, Natarajan, Pradeep, Lander, Eric S., Lubitz, Steven A., Ellinor, Patrick T., Kathiresan, Sekar

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Genetic analysis of right heart structure and function in 40,000 people von Pirruccello, James P., Di Achille, Paolo, Nauffal, Victor, Nekoui, Mahan, Friedman, Samuel F., Klarqvist, Marcus D. R., Chaffin, Mark D., Weng, Lu-Chen, Cunningham, Jonathan W., Khurshid, Shaan, Roselli, Carolina, Lin, Honghuang, Koyama, Satoshi, Ito, Kaoru, Kamatani, Yoichiro, Komuro, Issei, Jurgens, Sean J., Benjamin, Emelia J., Batra, Puneet, Natarajan, Pradeep, Ng, Kenney, Hoffmann, Udo, Lubitz, Steven A., Ho, Jennifer E., Lindsay, Mark E., Philippakis, Anthony A., Ellinor, Patrick T.

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The Effect of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibition on the Risk of Venous Thromboembolism von Marston, Nicholas A., Gurmu, Yared, Melloni, Giorgio E.M., Bonaca, Marc, Gencer, Baris, Sever, Peter S., Pedersen, Terje R., Keech, Anthony C., Roselli, Carolina, Lubitz, Steven A., Ellinor, Patrick T., O’Donoghue, Michelle L., Giugliano, Robert P., Ruff, Christian T., Sabatine, Marc S.

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A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression von Gupta, Rajat M., Hadaya, Joseph, Trehan, Aditi, Zekavat, Seyedeh M., Roselli, Carolina, Klarin, Derek, Emdin, Connor A., Hilvering, Catharina R.E., Bianchi, Valerio, Mueller, Christian, Khera, Amit V., Ryan, Russell J.H., Engreitz, Jesse M., Issner, Robbyn, Shoresh, Noam, Epstein, Charles B., de Laat, Wouter, Brown, Jonathan D., Schnabel, Renate B., Bernstein, Bradley E., Kathiresan, Sekar

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Genetic Risk Prediction of Atrial Fibrillation von Lubitz, Steven A, Yin, Xiaoyan, Lin, Henry J, Kolek, Matthew, Smith, J Gustav, Trompet, Stella, Rienstra, Michiel, Rost, Natalia S, Teixeira, Pedro L, Almgren, Peter, Anderson, Christopher D, Chen, Lin Y, Engström, Gunnar, Ford, Ian, Furie, Karen L, Guo, Xiuqing, Larson, Martin G, Lunetta, Kathryn L, Macfarlane, Peter W, Psaty, Bruce M, Soliman, Elsayed Z, Sotoodehnia, Nona, Stott, David J, Taylor, Kent D, Weng, Lu-Chen, Yao, Jie, Geelhoed, Bastiaan, Verweij, Niek, Siland, Joylene E, Kathiresan, Sekar, Roselli, Carolina, Roden, Dan, van der Harst, Pim, Darbar, Dawood, Jukema, J Wouter, Melander, Olle, Rosand, Jonathan, Rotter, Jerome I, Heckbert, Susan R, Ellinor, Patrick T, Alonso, Alvaro, Benjamin, Emelia J

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Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction von Khera, Amit V., Chaffin, Mark, Zekavat, Seyedeh M., Collins, Ryan L., Roselli, Carolina, Natarajan, Pradeep, Lichtman, Judith H., D’Onofrio, Gail, Mattera, Jennifer, Dreyer, Rachel, Spertus, John A., Taylor, Kent D., Psaty, Bruce M., Rich, Stephen S., Post, Wendy, Gupta, Namrata, Gabriel, Stacey, Lander, Eric, Ida Chen, Yii-Der, Talkowski, Michael E., Rotter, Jerome I., Krumholz, Harlan M., Kathiresan, Sekar

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Deep learning enables genetic analysis of the human thoracic aorta von Pirruccello, James P., Chaffin, Mark D., Chou, Elizabeth L., Fleming, Stephen J., Lin, Honghuang, Nekoui, Mahan, Khurshid, Shaan, Friedman, Samuel F., Bick, Alexander G., Arduini, Alessandro, Weng, Lu-Chen, Choi, Seung Hoan, Akkad, Amer-Denis, Batra, Puneet, Tucker, Nathan R., Hall, Amelia W., Roselli, Carolina, Benjamin, Emelia J., Vellarikkal, Shamsudheen K., Gupta, Rajat M., Stegmann, Christian M., Juric, Dejan, Stone, James R., Vasan, Ramachandran S., Ho, Jennifer E., Hoffmann, Udo, Lubitz, Steven A., Philippakis, Anthony A., Lindsay, Mark E., Ellinor, Patrick T.

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Genetic Susceptibility for Atrial Fibrillation in Patients Undergoing Atrial Fibrillation Ablation von Shoemaker, M. Benjamin, Husser, Daniela, Roselli, Carolina, Al Jazairi, Meelad, Chrispin, Jonathan, Kühne, Michael, Neumann, Benjamin, Knight, Stacey, Sun, Han, Mohanty, Sanghamitra, Shaffer, Christian, Thériault, Sébastien, Rinke, Lauren Lee, Siland, Joylene E., Crawford, Diane M., Ueberham, Laura, Zardkoohi, Omeed, Büttner, Petra, Geelhoed, Bastiaan, Blum, Steffen, Aeschbacher, Stefanie, Smith, Jonathan D., Van Wagoner, David R., Freudling, Rebecca, Müller-Nurasyid, Martina, Montgomery, Jay, Yoneda, Zachary, Wells, Quinn, Issa, Tariq, Weeke, Peter, Jacobs, Victoria, Van Gelder, Isabelle C., Hindricks, Gerhard, Barnard, John, Calkins, Hugh, Darbar, Dawood, Michaud, Greg, Kääb, Stefan, Ellinor, Patrick, Natale, Andrea, Chung, Mina, Nazarian, Saman, Cutler, Michael J., Sinner, Moritz F., Conen, David, Rienstra, Michiel, Bollmann, Andreas, Roden, Dan M., Lubitz, Steven

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Whole Exome Sequencing in Atrial Fibrillation von Lubitz, Steven A, Brody, Jennifer A, Bihlmeyer, Nathan A, Roselli, Carolina, Weng, Lu-Chen, Christophersen, Ingrid E, Alonso, Alvaro, Boerwinkle, Eric, Gibbs, Richard A, Bis, Joshua C, Cupples, L Adrienne, Mohler, Peter J, Nickerson, Deborah A, Muzny, Donna, Perez, Marco V, Psaty, Bruce M, Soliman, Elsayed Z, Sotoodehnia, Nona, Lunetta, Kathryn L, Benjamin, Emelia J, Heckbert, Susan R, Arking, Dan E, Ellinor, Patrick T, Lin, Honghuang

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Rare variant contribution to the heritability of coronary artery disease von Rocheleau, Ghislain, Clarke, Shoa L., Auguste, Gaëlle, Hasbani, Natalie R., Morrison, Alanna C., Heath, Adam S., Bielak, Lawrence F., Iyer, Kruthika R., Young, Erica P., Stitziel, Nathan O., Jun, Goo, Laurie, Cecelia, Broome, Jai G., Khan, Alyna T., Arnett, Donna K., Becker, Lewis C., Bis, Joshua C., Boerwinkle, Eric, Bowden, Donald W., Carson, April P., Ellinor, Patrick T., Fornage, Myriam, Franceschini, Nora, Freedman, Barry I., Heard-Costa, Nancy L., Hou, Lifang, Chen, Yii-Der Ida, Kenny, Eimear E., Kooperberg, Charles, Kral, Brian G., Loos, Ruth J. F., Lutz, Sharon M., Manson, JoAnn E., Martin, Lisa W., Mitchell, Braxton D., Nassir, Rami, Palmer, Nicholette D., Post, Wendy S., Preuss, Michael H., Psaty, Bruce M., Raffield, Laura M., Regan, Elizabeth A., Rich, Stephen S., Smith, Jennifer A., Taylor, Kent D., Yanek, Lisa R., Young, Kendra A., Hilliard, Austin T., Tcheandjieu, Catherine, Peyser, Patricia A., Vasan, Ramachandran S., Rotter, Jerome I., Miller, Clint L., Assimes, Themistocles L., de Vries, Paul S., Do, Ron

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Abstract 9393: A Genetic Risk Score to Predict Peripheral Artery Disease and Acute Limb Ischemia in Patients With Cardiometabolic Disease von Patel, Siddharth M, Marston, Nicholas A, Melloni, Giorgio E, Kamanu, Frederick K, Roselli, Carolina, Antman, Elliott M, Bhatt, Deepak L, Braunwald, Eugene, Cannon, Christopher P, Odonoghue, Michelle L, Giugliano, Robert P, Mosenzon, Ofri, Scirica, Benjamin M, Lubitz, Steven A, Ellinor, Patrick T, Bonaca, Marc P, Sabatine, Marc S, Ruff, Christian T

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Deep learning enables genetic analysis of the human thoracic aorta von Pirruccello, James P, Chaffin, Mark D, Chou, Elizabeth L, Fleming, Stephen J, Lin, Honghuang, Nekoui, Mahan, Khurshid, Shaan, Friedman, Samuel F, Bick, Alexander G, Arduini, Alessandro, Weng, Lu-Chen, Choi, Seung Hoan, Akkad, Amer-Denis, Batra, Puneet, Tucker, Nathan R, Hall, Amelia W, Roselli, Carolina, Benjamin, Emelia J, Vellarikkal, Shamsudheen K, Gupta, Rajat M, Stegmann, Christian M, Juric, Dejan, Stone, James R, Vasan, Ramachandran S, Ho, Jennifer E, Hoffmann, Udo, Lubitz, Steven A, Philippakis, Anthony A, Lindsay, Mark E, Ellinor, Patrick T

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Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations von Khera, Amit V, Chaffin, Mark, Aragam, Krishna G, Haas, Mary E, Roselli, Carolina, Choi, Seung Hoan, Natarajan, Pradeep, Lander, Eric S, Lubitz, Steven A, Ellinor, Patrick T, Kathiresan, Sekar

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An APOO Pseudogene on Chromosome 5q Is Associated With Low-Density Lipoprotein Cholesterol Levels von O’Hare, Elizabeth A, Wang, Xiaochun, Chang, Yen-Pei C, Anderson, Peter, Applebaum-Bowden, Debora, Aslibekyan, Stella, Graham Barr, R, Broeckel, Ulrich, Burchard, Esteban, Cardwell, Jonathan, Casaburi, Richard, Choi, Seung Hoan, Curran, Joanne, Curtis, Jeffrey, Custer, Brian, David, Sean, Davis, Colleen, Daya, Michelle, Deka, Ranjan, Duan, Qing, Duggirala, Ravi, Dutcher, Susan, Eaton, Charles, Ellinor, Patrick, Farnam, Leanna, Franceschini, Nora, Fu, Mao, Fulton, Lucinda, Gabriel, Stacey, Gan, Weiniu, Geng, Xiaoqi (Priscilla), Germer, Soren, Gignoux, Chris, Charles Gu, C, Guan, Yue, Harris, Daniel, Heavner, Ben, Heckbert, Susan, Hixson, James, Hokanson, John, Hsiung, Chao (Agnes), Jackson, Rebecca, Jaquish, Cashell, Jones, Kimberly, Kaufman, Laura, Kessler, Michael, Khan, Alyna, Konkle, Barbara, Lange, Leslie, Laurie, Cecelia, Lee, Seunggeun, Liu, Simin, Liu, Yongmei, Loos, Ruth, Lunetta, Kathryn, Luo, James, Margolin, Lauren, McArdle, Patrick, McDonald, Merry-Lynn, McFarland, Sean, Meyers, Deborah, Min, Nancy, Minster, Ryan L, O’Connell, Jeff, Pattison, Jessica Tangarone, Peyser, Patricia, Becker, Julia Powers, Qiao, Dandi, Rao, D.C, Redline, Susan, Regan, Elizabeth, Rice, Ken, Roselli, Carolina, Ruuska, Sarah, Salimi, Shabnam, Shetty, Amol, Shetty, Aniket, Benjamin Shoemaker, M, Silverman, Edwin, Smith, Jennifer, Smith, Josh, Smith, Nicholas, Snively, Beverly, Sylvia, Jody, Szpiro, Adam, Taub, Margaret, Taylor, Kent, Tiwari, Hemant, Tsai, Michael, Vrieze, Scott, Walts, Avram, Weeks, Daniel E, Weng, Lu-Chen, Keoki Williams, L, Wong, Quenna, Xu, Huichun, Yang, Rongze, Zaghloul, Norann, Zhou, Xiang, Zody, Michael

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Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation von Christophersen, Ingrid E, Rienstra, Michiel, Roselli, Carolina, Geelhoed, Bastiaan, Barnard, John, Lin, Honghuang, Smith, Albert V, Albert, Christine M, Chaffin, Mark, Li, Molong, Low, Siew-Kee, Smith, J Gustav, Brody, Jennifer A, Dörr, Marcus, Trompet, Stella, Gustafsson, Stefan, Schurmann, Claudia, Kleber, Marcus E, R V R Horimoto, Andrea, Sinisalo, Juha, Yao, Jie, Radmanesh, Farid, Choi, Seung Hoan, Clauss, Sebastian, Deo, Rajat, Rader, Daniel J, Sun, Albert, Hopewell, Jemma C, Debette, Stephanie, Yang, Qiong, Worrall, Bradford B, Paré, Guillaume, Kamatani, Yoichiro, Hagemeijer, Yanick P, Verweij, Niek, Van Wagoner, David R, Psaty, Bruce M, Ridker, Paul M, Magnani, Jared W, Harris, Tamara B, Launer, Lenore J, Shoemaker, M Benjamin, Padmanabhan, Sandosh, Haessler, Jeffrey, Waldenberger, Melanie, Lichtner, Peter, Arendt, Marina, Kähönen, Mika, Mansur, Alfredo J, Smith, Blair H, Scott, Stuart A, Lu, Yingchang, Bottinger, Erwin B, Lindgren, Cecilia M, Morris, Andrew P, Ford, Ian, Reiner, Alex P, Delgado, Graciela, Chen, Lin Y, Chen, Yii-Der Ida, Sandhu, Roopinder K, Boerwinkle, Eric, Eisele, Lewin, Lannfelt, Lars, Rost, Natalia, Anderson, Christopher D, Taylor, Kent D, Campbell, Archie, Hocking, Lynne J, Vlachopoulou, Efthymia, Orho-Melander, Marju, Hamsten, Anders, Kriebel, Jennifer, Newton-Cheh, Christopher, Shaffer, Christian, Heilmann-Heimbach, Stefanie, Almgren, Peter, Huang, Paul L, Sotoodehnia, Nona, Soliman, Elsayed Z, Uitterlinden, Andre G, Sinner, Moritz F, Lin, Henry J, Dichgans, Martin, Ingelsson, Erik, Melander, Olle, J F Loos, Ruth, Laurikka, Jari, Rosand, Jonathan, Lokki, Marja-Liisa, Kathiresan, Sekar, Hayward, Caroline, Chung, Mina K, Roden, Dan M, Kääb, Stefan, Chasman, Daniel I, Benjamin, Emelia J, Tanaka, Toshihiro, Lunetta, Kathryn L, Ellinor, Patrick T

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Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes von Malik, Rainer, , Mishra, Aniket, Almgren, Peter, Bartz, Traci M, Brown, Robert D, Carrera, Caty, Correa, Adolfo, Cotlarciuc, Ioana, den Hoed, Marcel, Engelter, Stefan T, Falcone, Guido J, Gudnason, Vilmundur, Gustafsson, Stefan, Hassan, Ahamad, Ikram, M. Arfan, Johnson, Julie A, Keene, Keith L, Langefeld, Carl D, Langenberg, Claudia, Leys, Didier, Lewis, Cathryn M, Lorentzen, Erik, Manichaikul, Ani, Meschia, James F, Nalls, Michael A, Rexrode, Kathryn M, Rotter, Jerome I, Sakaue, Saori, Sale, Michele M, Salomaa, Veikko, Sharma, Pankaj, Slowik, Agnieszka, Tanislav, Christian, Taylor, Kent D, Thorleifsson, Gudmar, Tiedt, Steffen, van Duijn, Cornelia M, Walters, Matthew, Bis, Joshua C, Pastinen, Tomi, Trégouët, David A, Roselli, Carolina, Ellinor, Patrick T, Tai, E. Shyong, Kato, Norihiro, He, Jiang, Chambers, John C, Takeuchi, Fumihiko, Johnson, Andrew D, Sanghera, Dharambir K, Melander, Olle, Jern, Christina, Rolfs, Arndt, Woo, Daniel, Hopewell, Jemma C, Seshadri, Sudha, Dichgans, Martin, Amin, Najaf, Aparicio, Hugo S, Berr, Claudine, Cheng, Yu-Ching, Chowhan, Ayesha, Cullell, Natalia, Delavaran, Hossein, Ibanez, Laura, Ingelsson, Martin, Iwasaki, Motoki, Jousilahti, Pekka, Kaffashian, Sara, Kitazono, Takanari, Koudstaal, Peter J, Laurie, Cathy C, Liu, Yong Mei, Lopez, Oscar L, Makoto, Hirata, Martinez-Majander, Nicolas, Morris, Andrew P, Muiño, Elena, Peddareddygari, Leema Reddy, Pileggi, Silvana, Riba-Llena, Iolanda, Romero, Jose R, Sarin, Antti-Pekka, Sarnowski, Chloe, Satizabal, Claudia L, Satoh, Mamoru, Sibolt, Gerli, Sigurdsson, Ásgeir, Smith, Albert, Stine, O. Colin, Strauch, Konstantin, Takai, Takako, Tanaka, Hideo, Tanno, Kozo, Tomppo, Liisa, Torres-Aguila, Nuria P, Tsugane, Shoichiro, Valdimarsson, Einar M, Wong, Quenna

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Whole Exome Sequencing in Atrial Fibrillation von Lubitz, Steven A, Brody, Jennifer A, Bihlmeyer, Nathan A, Roselli, Carolina, Weng, Lu-Chen, Christophersen, Ingrid E, Alonso, Alvaro, Boerwinkle, Eric, Gibbs, Richard A, Bis, Joshua C, Cupples, L. Adrienne, Mohler, Peter J, Nickerson, Deborah A, Muzny, Donna, Perez, Marco V, Psaty, Bruce M, Soliman, Elsayed Z, Sotoodehnia, Nona, Lunetta, Kathryn L, Benjamin, Emelia J, Heckbert, Susan R, Arking, Dan E, Ellinor, Patrick T, Lin, Honghuang

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