The tumor microenvironment is the main source of IL-6 for plasma cell tumor development in mice von Rosean, T R, Tompkins, V S, Olivier, A K, Sompallae, R, Norian, L A, Morse, H C, Waldschmidt, T J, Janz, S

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18F-FDG-PET/CT imaging in an IL-6- and MYC-driven mouse model of human multiple myeloma affords objective evaluation of plasma cell tumor progression and therapeutic response to th... von Duncan, K, Rosean, T R, Tompkins, V S, Olivier, A, Sompallae, R, Zhan, F, Tricot, G, Acevedo, M R, Ponto, L L B, Walsh, S A, Tygrett, L T, Berger, A J, Waldschmidt, T, Morse, H C, Sunderland, J J, Janz, S

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Adoptive B-cell transfer mouse model of human myeloma von Tompkins, V S, Rosean, T R, Holman, C J, DeHoedt, C, Olivier, A K, Duncan, K M, Jing, X, Foor, S D, Acevedo, M R, Walsh, S A, Tricot, G, Zhan, F, Janz, S

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KSHV-encoded vIL-6 collaborates with deregulated c-Myc to drive plasmablastic neoplasms in mice von Rosean, T R, Holman, C J, Tompkins, V S, Jing, X, Krasowski, M D, Rose-John, S, Janz, S

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Transgenic mouse model of IgM+ lymphoproliferative disease mimicking Waldenström macroglobulinemia von Tompkins, V S, Sompallae, R, Rosean, T R, Walsh, S, Acevedo, M, Kovalchuk, A L, Han, S-S, Jing, X, Holman, C, Rehg, J E, Herms, S, Sunderland, J S, Morse, H C, Janz, S

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(18)F-FDG-PET/CT imaging in an IL-6- and MYC-driven mouse model of human multiple myeloma affords objective evaluation of plasma cell tumor progression and therapeutic response to... von Duncan, K, Rosean, T R, Tompkins, V S, Olivier, A, Sompallae, R, Zhan, F, Tricot, G, Acevedo, M R, Ponto, L L B, Walsh, S A, Tygrett, L T, Berger, A J, Waldschmidt, T, Morse, 3rd, H C, Sunderland, J J, Janz, S

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The influence of the commensal microbiota on distal tumor-promoting inflammation von Buchta Rosean, Claire M., Rutkowski, Melanie R.

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Preexisting Commensal Dysbiosis Is a Host-Intrinsic Regulator of Tissue Inflammation and Tumor Cell Dissemination in Hormone Receptor-Positive Breast Cancer von Buchta Rosean, Claire, Bostic, Raegan R, Ferey, Joshua C M, Feng, Tzu-Yu, Azar, Francesca N, Tung, Kenneth S, Dozmorov, Mikhail G, Smirnova, Ekaterina, Bos, Paula D, Rutkowski, Melanie R

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Role of NK cell subsets in organ-specific murine melanoma metastasis von Ballas, Zuhair K, Buchta, Claire M, Rosean, Timothy R, Heusel, Jonathan W, Shey, Michael R

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Eradication of metastatic renal cell carcinoma after adenovirus-encoded TNF-related apoptosis-inducing ligand (TRAIL)/CpG immunotherapy von Norian, Lyse A, Kresowik, Timothy P, Rosevear, Henry M, James, Britnie R, Rosean, Timothy R, Lightfoot, Andrew J, Kucaba, Tamara A, Schwarz, Christopher, Weydert, Christine J, Henry, Michael D, Griffith, Thomas S

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Impact of the microbiome on cancer progression and response to anti-cancer therapies von Buchta Rosean, Claire, Feng, Tzu-Yu, Azar, Francesca N, Rutkowski, Melanie R

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HHV-8–encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice von Suthaus, Jan, Stuhlmann-Laeisz, Christiane, Tompkins, Van S., Rosean, Timothy R., Klapper, Wolfram, Tosato, Giovanna, Janz, Siegfried, Scheller, Jürgen, Rose-John, Stefan

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Preclinical validation of interleukin 6 as a therapeutic target in multiple myeloma von Rosean, Timothy R., Tompkins, Van S., Tricot, Guido, Holman, Carol J., Olivier, Alicia K., Zhan, Fenghuang, Janz, Siegfried

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NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas von Reed, Sara M, Hagen, Jussara, Muniz, Viviane P, Rosean, Timothy R, Borcherding, Nick, Sciegienka, Sebastian, Goeken, J Adam, Naumann, Paul W, Zhang, Weizhou, Tompkins, Van S, Janz, Siegfried, Meyerholz, David K, Quelle, Dawn E

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Identification of novel plasma cell subsets in a mouse model of SLE von Rosean, Timothy R, Loo, William, Erickson, Loren D

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Reciprocal Interactions Between the Gut Microbiome and Mammary Tissue Mast Cells Promote Metastatic Dissemination of HR+ Breast Tumors von Feng, Tzu-Yu, Azar, Francesca N, Dreger, Sally A, Rosean, Claire Buchta, McGinty, Mitchell T, Putelo, Audrey M, Kolli, Sree H, Carey, Maureen A, Greenfield, Stephanie, Fowler, Wesley J, Robinson, Stephen D, Rutkowski, Melanie R

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Platinum Chemotherapy Induces Lymphangiogenesis in Cancerous and Healthy Tissues That Can be Prevented With Adjuvant Anti-VEGFR3 Therapy von Harris, Alexandra R, Esparza, Savieay, Azimi, Mohammad S, Cornelison, Robert, Azar, Francesca N, Llaneza, Danielle C, Belanger, Maura, Mathew, Alexander, Tkachenko, Svyatoslav, Perez, Matthew J, Rosean, Claire Buchta, Bostic, Raegan R, Cornelison, R Chase, Tate, Kinsley M, Peirce-Cottler, Shayn M, Paquette, Cherie, Mills, Anne, Landen, Charles N, Saucerman, Jeff, Dillon, Patrick M, Pompano, Rebecca R, Rutkowski, Melanie A, Munson, Jennifer M

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The role of plasma cell precursors in a mouse model of lupus von Rosean, Timothy R, Loo, William, Erickson, Loren D

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Commensal dysbiosis modulates the tumor microenvironment in breast cancer and diminishes efficacy of PD-L1 inhibition von Rutkowski, Melanie R., Rosean, Claire M., Bostic, Raegan, Feng, Tzu-Yu

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Abstract A64: Commensal dysbiosis alters the tumor microenvironment in breast cancer and diminishes efficacy of PD-L1 blockade von Rosean, Claire Buchta, Bostic, Raegan, Feng, Tzu Yu, Rutkowski, Melanie R.

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