Exploration of human serum albumin binding sites by docking and molecular dynamics flexible ligand-protein interactions von Deeb, Omar, Rosales-Hernández, Martha Cecilia, Gómez-Castro, Carlos, Garduño-Juárez, Ramón, Correa-Basurto, José

Volltext

Exploring the biotransformation of N‐(2‐hydroxyphenyl)‐2‐propylpentanamide (an aryl valproic acid derivative) by CYP2C11, using in silico predictions and in vitro studies von Mendieta‐Wejebe, Jessica Elena, Silva‐Trujillo, Arianna, Bello, Martiniano, Mendoza‐Figueroa, Humberto L., Galindo‐Alvarez, Norma Lizeth, Albores, Arnulfo, Tamay‐Cach, Feliciano, Rosales‐Hernández, Martha Cecilia, Romero‐Castro, Aurelio, Correa‐Basurto, José

Volltext

Pharmacokinetics in Wistar Rats of 5-[(4-Carboxybutanoyl)Amino]-2-Hydroxybenzoic Acid: A Novel Synthetic Derivative of 5-Aminosalicylic Acid (5-ASA) with Possible Anti-Inflammatory... von Romero-Castro, Aurelio, Gutiérrez-Sánchez, Mara, Correa-Basurto, José, Rosales Hernández, Martha Cecilia, Padilla Martínez, Itzia Irene, Mendieta-Wejebe, Jessica Elena

Volltext

Exploring the Benzazoles Derivatives as Pharmacophores for AChE, BACE1, and as Anti-Aβ Aggregation to Find Multitarget Compounds against Alzheimer's Disease von Rosales Hernández, Martha Cecilia, Olvera-Valdez, Marycruz, Velazquez Toledano, Jazziel, Mendieta Wejebe, Jessica Elena, Fragoso Morales, Leticia Guadalupe, Cruz, Alejandro

Volltext

New compounds from heterocyclic amines scaffold with multitarget inhibitory activity on Aβ aggregation, AChE, and BACE1 in the Alzheimer disease von García Marín, Iohanan Daniel, Camarillo López, Raúl Horacio, Martínez, Oscar Aurelio, Padilla-Martínez, Itzia Irene, Correa-Basurto, José, Rosales-Hernández, Martha Cecilia

Volltext

PAMAM-G4 protect the N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA) and maintain its antiproliferative effects on MCF-7 von Ortiz-Morales, Alma Alicia, García-Vázquez, Juan Benjamín, Fragoso-Vázquez, Manuel Jonathan, Rosales-Hernández, Martha Cecilia, Fragoso-Morales, Leticia Guadalupe, Estrada-Pérez, Alan Rubén, Correa-Basurto, José

Volltext

Synthesis and Biological Importance of 2-(thio)ureabenzothiazoles von Rosales-Hernández, Martha Cecilia, Mendieta-Wejebe, Jessica E, Padilla-Martínez, Itzia I, García-Báez, Efrén V, Cruz, Alejandro

Volltext

Repurposing FDA Drug Compounds against Breast Cancer by Targeting EGFR/HER2 von Balbuena-Rebolledo, Irving, Padilla-Martínez, Itzia Irene, Rosales-Hernández, Martha Cecilia, Bello, Martiniano

Volltext

Preclinical Pharmacokinetics and Acute Toxicity in Rats of 5-{[(2E)-3-Bromo-3-carboxyprop-2-enoyl]amino}-2-hydroxybenzoic Acid: A Novel 5-Aminosalicylic Acid Derivative with Potent... von Gutiérrez-Sánchez, Mara, Romero-Castro, Aurelio, Correa-Basurto, José, Rosales-Hernández, Martha Cecilia, Padilla-Martínez, Itzia Irene, Mendieta-Wejebe, Jessica Elena

Volltext

Protective effect of (E)-(2,4-dihydroxy)-α-aminocinnamic acid, a hydroxy cinnamic acid derivative, in an ulcerative colitis model induced by TNBS von Rivera Antonio, Astrid Mayleth, Padilla Martínez, Itzia Irene, Márquez-Flores, Yazmín Karina, Juárez Solano, Alan Hipólito, Torres Ramos, Mónica A, Rosales Hernández, Martha Cecilia

Volltext

Determining Structural Changes for Ligand Recognition between Human and Rat Phosphorylated BACE1 in Silico and Its Phosphorylation by GSK3β at Thr252 by in Vitro Studies von Velazquez Toledano, Jazziel, Bello, Martiniano, Correa Basurto, José, Guerrero González, Isaac, Pacheco-Yépez, Judith, Rosales Hernández, Martha Cecilia

Volltext

Recent Advances by In Silico and In Vitro Studies of Amyloid-β 1-42 Fibril Depicted a S-Shape Conformation von Acosta, Daniel Miguel Ángel Villalobos, Vega, Brenda Chimal, Basurto, José Correa, Morales, Leticia Guadalupe Fragoso, Rosales Hernández, Martha Cecilia

Volltext

Implication of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase and Its Inhibitors in Alzheimer's Disease Murine Models von Fragoso-Morales, Leticia Guadalupe, Correa-Basurto, José, Rosales-Hernández, Martha Cecilia

Volltext

Tert-butyl-(4-hydroxy-3-((3-(2-methylpiperidin-yl)propyl)carbamoyl)phenyl)carbamate Has Moderated Protective Activity in Astrocytes Stimulated with Amyloid Beta 1-42 and in a Scopo... von Camarillo-López, Raúl Horacio, Hernández Rodríguez, Maricarmen, Torres-Ramos, Mónica Adriana, Arciniega-Martínez, Ivonne Maciel, García-Marín, Iohanan Daniel, Correa Basurto, José, Méndez Méndez, Juan Vicente, Rosales-Hernández, Martha Cecilia

Volltext

LDH-A Promotes Metabolic Rewiring in Leucocytes from the Intestine of Rats Treated with TNBS von Mendoza-Arroyo, Belen, Rosales-Hernández, Martha Cecilia, Pacheco-Yépez, Judith, Rivera-Antonio, Astrid Mayleth, Márquez-Flores, Yazmín Karina, Cárdenas-Jaramillo, Luz María, Reséndiz-Albor, Aldo Arturo, Arciniega-Martínez, Ivonne Maciel, Cruz-Hernández, Teresita Rocío, Abarca-Rojano, Edgar

Volltext

Novel 5-aminosalicylic derivatives as anti-inflammatories and myeloperoxidase inhibitors evaluated in silico, in vitro and ex vivo von Cabrera Pérez, Laura Cristina, Gutiérrez Sánchez, Mara, Mendieta Wejebe, Jessica Elena, Hernández Rgodríguez, Maricarmen, Fragoso Vázquez, Manuel Jonathan, Salazar, Juan Rodrigo, Correa Basurto, José, Padilla Martínez, Itzia Irene, Rosales Hernández, Martha Cecilia

Volltext

Evaluation of F3S4-m loaded liposomes as anti-AChE and its cytotoxic activity in PC12 and HMC3 cells von Camarillo López, Raúl Horacio, Fragoso Morales, Leticia Guadalupe, Delgado Cárdenas, Lilia Fernanda, Rivera Antonio, Astrid Mayleth, Corea, Mónica, Santos Macías, Juan Israel, Olvera Valdez, Marycruz, Rosales Hernández, Martha Cecilia

Volltext

In silico study suggests potential drugs that target CD151 to treat breast cancer and glioblastoma von Ramírez‐Salinas, Gema, Rosales‐Hernandéz, Martha Cecilia, Correa‐Basurto, José, Guerrero‐González, Issac, Hernández‐Castro, Selene Saraí, Martinez‐Archundia, Marlet

Volltext

Exploration of the valproic acid binding site on histone deacetylase 8 using docking and molecular dynamic simulations von Bermúdez-Lugo, Jorge Antonio, Perez-Gonzalez, Oscar, Rosales-Hernández, Martha Cecilia, Ilizaliturri-Flores, Ian, Trujillo-Ferrara, José, Correa-Basurto, Jose

Volltext

Hydroxamic acid derivatives as HDAC1, HDAC6 and HDAC8 inhibitors with antiproliferative activity in cancer cell lines von Sixto-López, Yudibeth, Gómez-Vidal, José Antonio, de Pedro, Nuria, Bello, Martiniano, Rosales-Hernández, Martha Cecilia, Correa-Basurto, José

Volltext