Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer’s disease (AD) mouse model and is increased at early stage in sporadic AD brain von Valverde, Audrey, Dunys, Julie, Lorivel, Thomas, Debayle, Delphine, Gay, Anne-Sophie, Lacas-Gervais, Sandra, Roques, Bernard. P., Chami, Mounia, Checler, Frédéric

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Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain von Roques, Bernard P., Fournié-Zaluski, Marie-Claude, Wurm, Michel

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Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects von Kandasamy, Ram, Hillhouse, Todd M., Livingston, Kathryn E., Kochan, Kelsey E., Meurice, Claire, Eans, Shainnel O., Li, Ming-Hua, White, Andrew D., Roques, Bernard P., McLaughlin, Jay P., Ingram, Susan L., Burford, Neil T., Alt, Andrew, Traynor, John R.

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Molecular mechanisms in Alzheimer's disease and related potential treatments such as structural target convergence of antibodies and simple organic molecules von Oumata, Nassima, Lu, Kui, Teng, Yuou, Cavé, Christian, Peng, Yu, Galons, Hervé, Roques, Bernard P.

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NI956/QGC006, a Potent Orally Active, Brain-Penetrating Aminopeptidase A Inhibitor for Treating Hypertension von Keck, Mathilde, De Almeida, Hugo, Compère, Delphine, Inguimbert, Nicolas, Flahault, Adrien, Balavoine, Fabrice, Roques, Bernard, Llorens-Cortes, Catherine

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Pain inhibition by blocking leukocytic and neuronal opioid peptidases in peripheral inflamed tissue von Schreiter, Anja, Gore, Carmen, Labuz, Dominika, Fournie‐Zaluski, Marie‐Claude, Roques, Bernard P., Stein, Christoph, Machelska, Halina

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Central Antihypertensive Effects of Orally Active Aminopeptidase A Inhibitors in Spontaneously Hypertensive Rats von Marc, Yannick, Gao, Ji, Balavoine, Fabrice, Michaud, Annie, Roques, Bernard P, Llorens-Cortes, Catherine

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Randomised, Double-Blind, Placebo-Controlled, Dose-Escalating Phase I Study of QGC001, a Centrally Acting Aminopeptidase A Inhibitor Prodrug von Balavoine, Fabrice, Azizi, Michel, Bergerot, Damien, De Mota, Nadia, Patouret, Rémi, Roques, Bernard P., Llorens-Cortes, Catherine

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New Orally Active Dual Enkephalinase Inhibitors (DENKIs) for Central and Peripheral Pain Treatment von Poras, Hervé, Bonnard, Elisabeth, Dangé, Emilie, Fournié-Zaluski, Marie-Claude, Roques, Bernard P

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Preventive and alleviative effects of the dual enkephalinase inhibitor (Denki) PL265 in a murine model of neuropathic pain von Bonnard, Elisabeth, Poras, Hervé, Fournié-Zaluski, Marie-Claude, Roques, Bernard P.

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Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum von Kupchik, Yonatan M, Scofield, Michael D, Rice, Kenner C, Cheng, Kejun, Roques, Bernard P, Kalivas, Peter W

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Obligatory Metabolism of Angiotensin II to Angiotensin III for Zona Glomerulosa Cell–Mediated Relaxations of Bovine Adrenal Cortical Arteries von Kopf, Phillip G, Park, Sang-Kyu, Herrnreiter, Anja, Krause, Christian, Roques, Bernard P, Campbell, William B

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TGF-β and opioid receptor signaling crosstalk results in improvement of endogenous and exogenous opioid analgesia under pathological pain conditions von Lantero, Aquilino, Tramullas, Mónica, Pílar-Cuellar, Fuencisla, Valdizán, Elsa, Santillán, Rosa, Roques, Bernard P, Hurlé, María A

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Aminopeptidase A contributes to the N-terminal truncation of amyloid β-peptide von Sevalle, Jean, Amoyel, Audrey, Robert, Philippe, Fournié-Zaluski, Marie-Claude, Roques, Bernard, Checler, Frédéric

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Orally Active Aminopeptidase A Inhibitors Reduce Blood Pressure: A New Strategy for Treating Hypertension von Bodineau, Laurence, Frugière, Alain, Marc, Yannick, Inguimbert, Nicolas, Fassot, Céline, Balavoine, Fabrice, Roques, Bernard, Llorens-Cortes, Catherine

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How the HIV-1 Nucleocapsid Protein Binds and Destabilises the (−)Primer Binding Site During Reverse Transcription von Bourbigot, Sarah, Ramalanjaona, Nick, Boudier, Christian, Salgado, Gilmar F.J., Roques, Bernard P., Mély, Yves, Bouaziz, Serge, Morellet, Nelly

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Endogenous Opioids as Physiological Antidepressants: Complementary Role of Delta Receptors and Dopamine von JUTKIEWICZ, Emily M, ROQUES, Bernard P

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Conversion of Renal Angiotensin II to Angiotensin III Is Critical for AT2 Receptor-Mediated Natriuresis In Rats von Padia, Shetal H, Kemp, Brandon A, Howell, Nancy L, Fournie-Zaluski, Marie-Claude, Roques, Bernard P, Carey, Robert M

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Protection of endogenous enkephalin catabolism as natural approach to novel analgesic and antidepressant drugs von Noble, Florence, Roques, Bernard P

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Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding von Gajiwala, Ketan S, Chen, Hua, Cornille, Fabrice, Roques, Bernard P, Reith, Walter, Mach, Bernard, Burley, Stephen K

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