A Quantitative Human Red Blood Cell Agglutination Assay for Characterisation of Galectin Inhibitors von Gasson, Rhianna, Roper, James A, Slack, Robert J

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Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis von John, Alison E., Graves, Rebecca H., Pun, K. Tao, Vitulli, Giovanni, Forty, Ellen J., Mercer, Paul F., Morrell, Josie L., Barrett, John W., Rogers, Rebecca F., Hafeji, Maryam, Bibby, Lloyd I., Gower, Elaine, Morrison, Valerie S., Man, Yim, Roper, James A., Luckett, Jeni C., Borthwick, Lee A., Barksby, Ben S., Burgoyne, Rachel A., Barnes, Rory, Le, Joelle, Flint, David J., Pyne, Susan, Habgood, Anthony, Organ, Louise A., Joseph, Chitra, Edwards-Pritchard, Rochelle C., Maher, Toby M., Fisher, Andrew J., Gudmann, Natasja Stæhr, Leeming, Diana J., Chambers, Rachel C., Lukey, Pauline T., Marshall, Richard P., Macdonald, Simon J. F., Jenkins, R. Gisli, Slack, Robert J.

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Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues von Hazell, Georgina G J, Yao, Song T, Roper, James A, Prossnitz, Eric R, O'Carroll, Anne-Marie, Lolait, Stephen J

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Resistance to anti-PD-1/anti-PD-L1: galectin-3 inhibition with GB1211 reverses galectin-3-induced blockade of pembrolizumab and atezolizumab binding to PD-1/PD-L1 von Mabbitt, Joseph, Holyer, Ian D., Roper, James A., Nilsson, Ulf J., Zetterberg, Fredrik R., Vuong, Lynda, Mackinnon, Alison C., Pedersen, Anders, Slack, Robert J.

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Determining the Affinity and Kinetics of Small Molecule Inhibitors of Galectin-1 Using Surface Plasmon Resonance von Kim, Henry, Kretz, Louis, Ronin, Céline, Starck, Christina, Roper, James A, Kahl-Knutson, Barbro, Peterson, Kristoffer, Leffler, Hakon, Nilsson, Ulf J, Pedersen, Anders, Zetterberg, Fredrik R, Slack, Robert J

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Ultrasonic Stimulation of Mouse Skin Reverses the Healing Delays in Diabetes and Aging by Activation of Rac1 von Roper, James A., Williamson, Rosalind C., Bally, Blandine, Cowell, Christopher A.M., Brooks, Rebecca, Stephens, Phil, Harrison, Andrew J., Bass, Mark D.

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Coronin-1C Protein and Caveolin Protein Provide Constitutive and Inducible Mechanisms of Rac1 Protein Trafficking von Williamson, Rosalind C., Cowell, Christopher A.M., Reville, Thomas, Roper, James A., Rendall, Thomas C.S., Bass, Mark D.

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G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei – serpentine gateways to neuroendocrine homeostasis von Hazell, Georgina G.J, Hindmarch, Charles C, Pope, George R, Roper, James A, Lightman, Stafford L, Murphy, David, O’Carroll, Anne-Marie, Lolait, Stephen J

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Discovery and Optimization of the First Highly Effective and Orally Available Galectin‑3 Inhibitors for Treatment of Fibrotic Disease von Zetterberg, Fredrik R., MacKinnon, Alison, Brimert, Thomas, Gravelle, Lise, Johnsson, Richard E., Kahl-Knutson, Barbro, Leffler, Hakon, Nilsson, Ulf J., Pedersen, Anders, Peterson, Kristoffer, Roper, James A., Schambye, Hans, Slack, Robert J., Tantawi, Susan

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Integrins as a drug target in liver fibrosis von Rahman, Syedia R., Roper, James A., Grove, Jane I., Aithal, Guruprasad P., Pun, K. Tao, Bennett, Andrew J.

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Discovery of Selective and Orally Available Galectin‑1 Inhibitors von Zetterberg, Fredrik R., Diehl, Carl, Håkansson, Maria, Kahl-Knutson, Barbro, Leffler, Hakon, Nilsson, Ulf J., Peterson, Kristoffer, Roper, James A., Slack, Robert J.

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Downregulation of the alpha v beta 6 Integrin via RGD Engagement Is Affinity and Time Dependent von Roper, James A., Wilkinson, Alex L., Gower, Elaine, Slack, Robert J.

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Downregulation of the αvβ6 Integrin via RGD Engagement Is Affinity and Time Dependent von Roper, James A, Wilkinson, Alex L, Gower, Elaine, Slack, Robert J

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Core Modifications of GSK3335103 toward Orally Bioavailable αvβ6 Inhibitors with Improved Synthetic Tractability von Hryczanek, Heather F., Barrett, John, Barrett, Tim N., Burley, Glenn A., Cookson, Rosa E., Hatley, Richard J. D., Measom, Nicholas D., Roper, James A., Rowedder, James E., Slack, Robert J., Śmieja, Connor B., Macdonald, Simon J. F.

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Core Modifications of GSK3335103 toward Orally Bioavailable α v β 6 Inhibitors with Improved Synthetic Tractability von Hryczanek, Heather F, Barrett, John, Barrett, Tim N, Burley, Glenn A, Cookson, Rosa E, Hatley, Richard J D, Measom, Nicholas D, Roper, James A, Rowedder, James E, Slack, Robert J, Śmieja, Connor B, Macdonald, Simon J F

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Discovery of the Selective and Orally Available Galectin‑1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer von Zetterberg, Fredrik R., Peterson, Kristoffer, Nilsson, Ulf J., Andréasson Dahlgren, Kajsa, Diehl, Carl, Holyer, Ian, Håkansson, Maria, Khabut, Areej, Kahl-Knutson, Barbro, Leffler, Hakon, MacKinnon, Alison C., Roper, James A., Slack, Robert J., Zarrizi, Reihaneh, Pedersen, Anders

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Syndecan and integrin interactomes: large complexes in small spaces von Roper, James A, Williamson, Rosalind C, Bass, Mark D

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Effect of GB1107, a novel galectin-3 inhibitor on pro-fibrotic signalling in the liver von MacKinnon, Alison C., Humphries, Duncan C., Herman, Kimberley, Roper, James A., Holyer, Ian, Mabbitt, Joseph, Mills, Ross, Nilsson, Ulf J., Leffler, Hakon, Pedersen, Anders, Schambye, Hans, Zetterberg, Fredrik, Slack, Robert J.

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The role of the arginine vasopressin Avp1b receptor in the acute neuroendocrine action of antidepressants von Stewart, Lesley Q, Roper, James A, Scott Young, W, O’Carroll, Anne-Marie, Lolait, Stephen J

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Galectin-1 Induces the Production of Immune-Suppressive Cytokines in Human and Mouse T Cells von Herman, Kimberly D., Holyer, Ian, Humphries, Duncan C., Adamska, Anna, Roper, James A., Peterson, Kristoffer, Zetterberg, Fredrik R., Pedersen, Anders, MacKinnon, Alison C., Slack, Robert J.

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