Molecular and Microenvironmental Determinants of Glioma Stem-Like Cell Survival and Invasion von Roos, Alison, Ding, Zonghui, Loftus, Joseph C, Tran, Nhan L

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EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival von Roos, Alison, Dhruv, Harshil D, Peng, Sen, Inge, Landon J, Tuncali, Serdar, Pineda, Michael, Millard, Nghia, Mayo, Zachary, Eschbacher, Jennifer M, Loftus, Joseph C, Winkles, Jeffrey A, Tran, Nhan L

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EGFRvIII Confers Sensitivity to Saracatinib in a STAT5-Dependent Manner in Glioblastoma von Blomquist, Mylan R, Eghlimi, Ryan, Beniwal, Angad, Grief, Dustin, Nascari, David G, Inge, Landon, Sereduk, Christopher P, Tuncali, Serdar, Roos, Alison, Inforzato, Hannah, Sharma, Ritin, Pirrotte, Patrick, Mehta, Shwetal, Fortin Ensign, Shannon P, Loftus, Joseph C, Tran, Nhan L

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A Novel Signaling Complex between TROY and EGFR Mediates Glioblastoma Cell Invasion von Ding, Zonghui, Roos, Alison, Kloss, Jean, Dhruv, Harshil, Peng, Sen, Pirrotte, Patrick, Eschbacher, Jennifer M, Tran, Nhan L, Loftus, Joseph C

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Two Independent Regions of Simian Virus 40 T Antigen Increase CBP/p300 Levels, Alter Patterns of Cellular Histone Acetylation, and Immortalize Primary Cells von Sáenz Robles, Maria Teresa, Shivalila, Chikdu, Wano, Jeremy, Sorrells, Shelly, Roos, Alison, Pipas, James M

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Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway von Dhruv, Harshil D., Roos, Alison, Tomboc, Patrick J., Tuncali, Serdar, Chavez, Ashley, Mathews, Ian, Berens, Michael E., Loftus, Joseph C., Tran, Nhan L.

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Real-world BRCA1/2 and homologous recombination deficiency testing dynamics and time to treatment discontinuation on PARP inhibitor first-line maintenance among patients with epith... von Previs, Rebecca, Roos, Alison, Vasudevan, Anupama, Blanc, Simon, Schnettler, Erica, Craver, Christopher, Severson, Eric, Sathyan, Pratheesh, Varughese, Prateesh, Ramkissoon, Shakti

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Effect of testing for BRCA1/2 on outcomes in patients with ovarian cancer treated with PARPi in 1st line maintenance (1LM) von Gordan, Lucio N., Vasudevan, Anupama, English, Sandy, Roos, Alison, Fares, Marielle, Aton, Lindsay, Wang, Brandon, Blanc, Simon

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A pilot precision medicine trial for children with diffuse intrinsic pontine glioma—PNOC003: A report from the Pacific Pediatric Neuro‐Oncology Consortium von Mueller, Sabine, Jain, Payal, Liang, Winnie S., Kilburn, Lindsay, Kline, Cassie, Gupta, Nalin, Panditharatna, Eshini, Magge, Suresh N., Zhang, Bo, Zhu, Yuankun, Crawford, John R., Banerjee, Anu, Nazemi, Kellie, Packer, Roger J., Petritsch, Claudia K., Truffaux, Nathalene, Roos, Alison, Nasser, Sara, Phillips, Joanna J., Solomon, David, Molinaro, Annette, Waanders, Angela J., Byron, Sara A., Berens, Michael E., Kuhn, John, Nazarian, Javad, Prados, Michael, Resnick, Adam C.

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Effective biomarker testing rates in a large U.S. community practice von Gordan, Lucio N., Diaz, Michael, Patel, Anjan Jayantilal, Fink, Matthew A., Wenk, David, Roos, Alison, Jiang, Yuqiu, Tam, Janice, Sathyan, Pratheesh, Febbo, Phillip G.

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Genomic profiling of NSCLC tumors with the TruSight oncology 500 assay provides broad coverage of clinically actionable genomic alterations and detection of known and novel associa... von Wallen, Zachary D., Nesline, Mary K., Tierno, Marni, Roos, Alison, Schnettler, Erica, Husain, Hatim, Sathyan, Pratheesh, Caveney, Brian, Eisenberg, Marcia, Severson, Eric A., Ramkissoon, Shakti H.

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TargetableBRAFandRAF1Alterations in Advanced Pediatric Cancers von Rankin, Andrew, Johnson, Adrienne, Roos, Alison, Kannan, Geoffrey, Knipstein, Jeffrey, Britt, Nicholas, Rosenzweig, Mark, Haberberger, James, Pavlick, Dean, Severson, Eric, Vergilio, Jo-Anne, Squillace, Rachel, Erlich, Rachel, Sathyan, Pratheesh, Cramer, Stuart, Kram, David, Ross, Jeffrey, Miller, Vince, Reddy, Prasanth, Alexander, Brian, Ali, Siraj M., Ramkissoon, Shakti

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Abstract 1878: PDZ-RhoGEF functions as a critical signaling effector for TROY von Ding, Zonghui, Roos, Alison, Kloss, Jean, Dhruv, Harshil, Symons, Marc, Tran, Nhan L., Loftus, Joseph C.

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Targetable BRAF and RAF1 Alterations in Advanced Pediatric Cancers von Rankin, Andrew, Johnson, Adrienne, Roos, Alison, Kannan, Geoffrey, Knipstein, Jeffrey, Britt, Nicholas, Rosenzweig, Mark, Haberberger, James, Pavlick, Dean, Severson, Eric, Vergilio, Jo‐Anne, Squillace, Rachel, Erlich, Rachel, Sathyan, Pratheesh, Cramer, Stuart, Kram, David, Ross, Jeffrey, Miller, Vince, Reddy, Prasanth, Alexander, Brian, Ali, Siraj M., Ramkissoon, Shakti

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Abstract 5036: Oncogenic role of Runx2 in the development of osteosarcoma von Roos, Alison, Yustein, Jason T., Donehower, Larry

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Loss of Runx2 sensitises osteosarcoma to chemotherapy-induced apoptosis von Roos, Alison, Satterfield, Laura, Zhao, Shuying, Fuja, Daniel, Shuck, Ryan, Hicks, M John, Donehower, Lawrence A, Yustein, Jason T

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The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance von Hersh, David S, Harder, Bryan G, Roos, Alison, Peng, Sen, Heath, Jonathan E, Legesse, Teklu, Kim, Anthony J, Woodworth, Graeme F, Tran, Nhan L, Winkles, Jeffrey A

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Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion von Byron, Sara A., Hendricks, William P. D., Nagulapally, Abhinav B., Kraveka, Jacqueline M., Ferguson, William S., Brown, Valerie, Eslin, Don E., Mitchell, Deanna, Cornelius, Albert, Roberts, William, Isakoff, Michael S., Oesterheld, Javier E., Wada, Randal K., Rawwas, Jawhar, Neville, Kathleen, Zage, Peter E., Harrod, Virginia L., Bergendahl, Genevieve, VanSickle, Elizabeth, Dykema, Karl, Bond, Jeffrey, Chou, Hsien-Chao, Wei, Jun S., Wen, Xinyu, Reardon, Hue, Roos, Alison, Nasser, Sara, Izatt, Tyler, Enriquez, Daniel, Hegde, Apurva M., Cisneros, Faith, Christofferson, Austin, Turner, Bryce, Szelinger, Szabolcs, Keats, Jonathan J., Halperin, Rebecca F., Khan, Javed, Sholler, Giselle L. Saulnier, Trent, Jeffrey M.

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Abstract 3462: EGFRvIII-Stat5 signaling enhances glioblastoma cell invasion von Roos, Alison, Dhruv, Harshil D., Peng, Sen, Inge, Landon J., Tuncali, Serdar, Pineda, Michael, Millard, Nghia, Winkles, Jeffrey A., Loftus, Joseph C., Tran, Nhan L.

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Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion von Byron, Sara A., Hendricks, William P. D., Nagulapally, Abhinav B., Kraveka, Jacqueline M., Ferguson, William S., Brown, Valerie I., Eslin, Don E., Mitchell, Deanna, Cornelius, Albert, Roberts, William, Isakoff, Michael S., Oesterheld, Javier E., Wada, Randal K., Rawwas, Jawhar, Neville, Kathleen, Zage, Peter E., Harrod, Virginia L., Bergendahl, Genevieve, VanSickle, Elizabeth, Dykema, Karl, Bond, Jeffrey, Chou, Hsien-Chao, Wei, Jun S., Wen, Xinyu, Reardon, Hue V., Roos, Alison, Nasser, Sara, Izatt, Tyler, Enriquez, Daniel, Hegde, Apurva M., Cisneros, Faith, Christofferson, Austin, Turner, Bryce, Szelinger, Szabolcs, Keats, Jonathan J., Halperin, Rebecca F., Khan, Javed, Sholler, Giselle L. Saulnier, Trent, Jeffrey M.

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