Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9 von Gundry, Michael C., Brunetti, Lorenzo, Lin, Angelique, Mayle, Allison E., Kitano, Ayumi, Wagner, Dimitrios, Hsu, Joanne I., Hoegenauer, Kevin A., Rooney, Cliona M., Goodell, Margaret A., Nakada, Daisuke

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Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent von Gomes-Silva, Diogo, Mukherjee, Malini, Srinivasan, Madhuwanti, Krenciute, Giedre, Dakhova, Olga, Zheng, Yueting, Cabral, Joaquim M.S., Rooney, Cliona M., Orange, Jordan S., Brenner, Malcolm K., Mamonkin, Maksim

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Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy von Di Stasi, Antonio, Tey, Siok-Keen, Dotti, Gianpietro, Fujita, Yuriko, Kennedy-Nasser, Alana, Martinez, Caridad, Straathof, Karin, Liu, Enli, Liu, Hao, Durett, April G, Grilley, Bambi, Cruz, Conrad R, Savoldo, Barbara, Gee, Adrian P, Schindler, John, Krance, Robert A, Heslop, Helen E, Spencer, David M, Rooney, Cliona M, Brenner, Malcolm K

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Constitutive Interleukin-7 Cytokine Signaling Enhances the Persistence of Epstein-Barr Virus-Specific T-Cells von Sharma, Sandhya, Sauer, Tim, Omer, Bilal A, Shum, Thomas, Rollins, Lisa A, Rooney, Cliona M

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Allogeneic, off-the-shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high-risk patients von Vasileiou, Spyridoula, Hill, LaQuisa, Kuvalekar, Manik, Workineh, Aster G, Watanabe, Ayumi, Velazquez, Yovana, Lulla, Suhasini, Mooney, Kimberly, Lapteva, Natalia, Grilley, Bambi J, Heslop, Helen E, Rooney, Cliona M, Brenner, Malcolm K, Eagar, Todd N, Carrum, George, Grimes, Kevin A, Leen, Ann M, Lulla, Premal

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Longitudinal analysis of the evolution of cellular immunity to SARS-CoV-2 induced by infection and vaccination von Vasileiou, Spyridoula, Kuvalekar, Manik, Velazquez, Yovana, Watanabe, Ayumi, Narula, Mansi, Workineh, Aster G, French-Kim, Matthew, Chavez, Alejandro Torres, Gilmore, Sarah, Rooney, Cliona M, Leen, Ann M

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Phase 1 Study of Intratumoral Pexa-Vec (JX-594), an Oncolytic and Immunotherapeutic Vaccinia Virus, in Pediatric Cancer Patients von Cripe, Timothy P, Ngo, Minhtran C, Geller, James I, Louis, Chrystal U, Currier, Mark A, Racadio, John M, Towbin, Alexander J, Rooney, Cliona M, Pelusio, Adina, Moon, Anne, Hwang, Tae-Ho, Burke, James M, Bell, John C, Kirn, David H, Breitbach, Caroline J

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Adoptive immunotherapy for primary immunodeficiency disorders with virus-specific T lymphocytes von Naik, Swati, MD, Nicholas, Sarah K., MD, Martinez, Caridad A., MD, Leen, Ann M., PhD, Hanley, Patrick J., PhD, Gottschalk, Steven M., MD, Rooney, Cliona M., PhD, Hanson, I. Celine, MD, PhD, Krance, Robert A., MD, Shpall, Elizabeth J., MD, Cruz, Conrad R., MD, PhD, Amrolia, Persis, MD, Lucchini, Giovanna, MD, Bunin, Nancy, MD, Heimall, Jennifer, MD, Klein, Orly R., MD, Gennery, Andrew R., MD, Slatter, Mary A., MD, Vickers, Mark A., MD, Orange, Jordan S., MD, PhD, Heslop, Helen E., MD, PhD, Bollard, Catherine M., MD, Keller, Michael D., MD

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A strategy to protect off-the-shelf cell therapy products using virus-specific T-cells engineered to eliminate alloreactive T-cells von Quach, David H, Becerra-Dominguez, Luis, Rouce, Rayne H, Rooney, Cliona M

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Post-transplant lymphoproliferative disorders von Gottschalk, Stephen, Rooney, Cliona M, Heslop, Helen E

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Characterization and treatment of chronic active Epstein-Barr virus disease: a 28-year experience in the United States von Cohen, Jeffrey I., Jaffe, Elaine S., Dale, Janet K., Pittaluga, Stefania, Heslop, Helen E., Rooney, Cliona M., Gottschalk, Stephen, Bollard, Catherine M., Rao, V. Koneti, Marques, Adriana, Burbelo, Peter D., Turk, Siu-Ping, Fulton, Rachael, Wayne, Alan S., Little, Richard F., Cairo, Mitchell S., El-Mallawany, Nader K., Fowler, Daniel, Sportes, Claude, Bishop, Michael R., Wilson, Wyndham, Straus, Stephen E.

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Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo von O’Neil, Richard T., Saha, Sunandan, Veach, Ruth Ann, Welch, Richard C., Woodard, Lauren E., Rooney, Cliona M., Wilson, Matthew H.

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Adoptive T-Cell Therapy for Epstein-Barr Virus-Related Lymphomas von Heslop, Helen E, Sharma, Sandhya, Rooney, Cliona M

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Banking on virus-specific T cells to fulfill the need for off-the-shelf cell therapies von Quach, David H., Lulla, Premal, Rooney, Cliona M.

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Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells von Morita, Daisuke, Nishio, Nobuhiro, Saito, Shoji, Tanaka, Miyuki, Kawashima, Nozomu, Okuno, Yusuke, Suzuki, Satoshi, Matsuda, Kazuyuki, Maeda, Yasuhiro, Wilson, Matthew H, Dotti, Gianpietro, Rooney, Cliona M, Takahashi, Yoshiyuki, Nakazawa, Yozo

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CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity von Sauer, Tim, Parikh, Kathan, Sharma, Sandhya, Omer, Bilal, Sedloev, David, Chen, Qian, Angenendt, Linus, Schliemann, Christoph, Schmitt, Michael, Müller-Tidow, Carsten, Gottschalk, Stephen, Rooney, Cliona M

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CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity von Sauer, Tim, Parikh, Kathan, Sharma, Sandhya, Omer, Bilal, Sedloev, David, Chen, Qian, Angenendt, Linus, Schliemann, Christoph, Schmitt, Michael, Müller-Tidow, Carsten, Gottschalk, Stephen, Rooney, Cliona M.

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CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma von Heczey, Andras, Louis, Chrystal U., Savoldo, Barbara, Dakhova, Olga, Durett, April, Grilley, Bambi, Liu, Hao, Wu, Mengfeng F., Mei, Zhuyong, Gee, Adrian, Mehta, Birju, Zhang, Huimin, Mahmood, Nadia, Tashiro, Haruko, Heslop, Helen E., Dotti, Gianpietro, Rooney, Cliona M., Brenner, Malcolm K.

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Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation von Gerdemann, Ulrike, Keukens, Laura, Keirnan, Jacqueline M., Katari, Usha L., Nguyen, Chinh T.Q., de Pagter, Anne P., Ramos, Carlos A., Kennedy-Nasser, Alana, Gottschalk, Stephen M., Heslop, Helen E., Brenner, Malcolm K., Rooney, Cliona M., Leen, Ann M.

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Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs von Ninomiya, Soranobu, Narala, Neeharika, Huye, Leslie, Yagyu, Shigeki, Savoldo, Barbara, Dotti, Gianpietro, Heslop, Helen E., Brenner, Malcolm K., Rooney, Cliona M., Ramos, Carlos A.

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