Clinical Implications of Dihydropyrimidine Dehydrogenase (DPD) Deficiency in Patients with Severe 5-Fluorouracil-associated Toxicity: Identification of New Mutations in the DPD Gen... von VAN KUILENBURG, André B. P, HAASJES, Janet, RICHEL, Dick J, ZOETEKOUW, Lida, VAN LENTHE, Henk, DE ABREU, Ronney A, MARING, Jan G, VREKEN, Peter, VAN GENNIP, Albert H

Volltext

Bcl-2 prevents loss of mitochondria in CCCP-induced apoptosis von de Graaf, Aniek O., van den Heuvel, Lambert P., Dijkman, Henry B.P.M., De Abreu, Ronney A., Birkenkamp, Kim U., de Witte, Theo, van der Reijden, Bert A., Smeitink, Jan A.M., Jansen, Joop H.

Volltext

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency von SUMI, Satoshi, MARINAKI, Anthony M, SIMMONDS, H. Anne, DULEY, John A, ARENAS, Monica, FAIRBANKS, Lynette, SHOBOWALE-BAKRE, Monsor, REES, David C, SWEE LAY THEIN, ANSARI, Azhar, SANDERSON, Jeremy, DE ABREU, Ronney A

Volltext

Thiopurine methyltransferase in acute lymphoblastic leukaemia: biochemical and molecular biological aspects von Brouwer, Connie, De Abreu, Ronney A., Keizer-Garritsen, Jenneke J., Lambooy, Lambert H.J., Ament, Kai, ter Riet, Patricia G.J.H., van Wering, Elisabeth R., Trijbels, Frans J.M., Veerman, Anjo J.P., Hoogerbrugge, Peter M., Bökkerink, Jos P.M.

Volltext

Role of 5′-nucleotidase in thiopurine metabolism: Enzyme kinetic profile and association with thio-GMP levels in patients with acute lymphoblastic leukemia during 6-mercaptopurine... von Brouwer, Connie, Vogels-Mentink, Trude M., Keizer-Garritsen, Jenneke J., Trijbels, Frans J.M., Bökkerink, Jos P.M., Hoogerbrugge, Peter M., van Wering, Elisabeth R., Veerman, Anjo J.P., De Abreu, Ronney A.

Volltext

Real-time analysis of Tyrosine hydroxylase gene expression: A sensitive and semiquantitative marker for minimal residual disease detection of neuroblastoma von LAMBOOY, Lambert H. J, GIDDING, Corrie E. M, VAN DEN HEUVEL, Lambert P, HULSBERGEN-VAN DE KAA, Christina A, LIGTENBERG, Marjolijn, BÖKKERINK, Jos P. M, DE ABREU, Ronney A

Volltext

Multi-Drug Therapy Schedules for SARS-COV-2: Smart Repurposing of Old Drugs von Bayoumy, Ahmed B., Ansari, Azhar R., De Abreu, Ronney A., Peters, Godefridus J., Mulder, Chris J.J.

Volltext

Monitoring of inosine monophosphate dehydrogenase activity in mononuclear cells of children with acute lymphoblastic leukemia: Enzymological and clinical aspects von Brouwer, Connie, Vermunt-de Koning, Diana G.M., Trueworthy, Robert C., ter Riet, Patricia G.J.H., Duley, John A., Trijbels, Frans J.M., Hoogerbrugge, Peter M., Bökkerink, Jos P.M., van Wering, Elisabeth R., De Abreu, Ronney A.

Volltext

2,8-Dihydroxyadenine Urolithiasis in a Patient with Considerable Residual Adenine Phosphoribosyltransferase Activity in Cell Extracts but with Mutations in Both Copies of APRT von Deng, Li, Yang, Min, Fründ, Stefan, Wessel, Torsten, De Abreu, Ronney A, Tischfield, Jay A, Sahota, Amrik

Volltext

Reduced purine 5’-nucleotidase activity in lymphocytes of patients with systemic lupus erythematosus: results of a pilot study von Stolk, Jan N, de Koning, Diana G M, Pennings, Arie H, De Abreu, Ronney A, van de Putte, Leo B A, Boerbooms, Agnes M Th

Volltext

Inhibition of DNA methylation in malignant MOLT F4 lymphoblasts by 6-mercaptopurine von Lambooy, Lambert H. J, Leegwater, Peter A. J, van den Heuvel, Lambert P, Bokkerink, Jos P, De Abreu, Ronney A

Volltext

Methotrexate in rheumatoid arthritis: An updatewith focus on mechanisms involved in toxicity von van Ede, Annelies E., Laan, Roland F.J.M., Blom, Henk J., De Abreu, Ronney A., van de Putte, Leo B.A.

Volltext

Effects on transmethylation by high-dose 6-mercaptopurine and methotrexate infusions during consolidation treatment of acute lymphoblastic leukemia von Keuzenkamp-Jansen, Carin W., De Abreu, Ronney A., Blom, Henk J., Bökkerink, Jos P.M., Trijbels, J.M.Frans

Volltext

Inhibition of IMP Dehydrogenase by Mycophenolic Acid in Molt F4 Human Malignant Lymphoblasts von Stet, Elisabet H, De Abreu, Ronney A, Bökkerink, Jos P M, Lambooy, Lambert H J, Vogels-Mentink, Trade M, Keizer-Garritsen, Jenneke J, Trijbels, Frans J M

Volltext

High-performance liquid chromatographic assay for identification and quantitation of nucleotides in lymphocytes and malignant lymphoblasts von De Abreu, Ronney A., van Baal, John M., Bakkeren, Jan A.J.M., De Bruyn, Chris H.M.M., Schretlen, Egbert D.A.M.

Volltext

Localization of the ICF Syndrome to Chromosome 20 by Homozygosity Mapping von Wijmenga, Cisca, van den Heuvel, Lambert P. W.J., Strengman, Eric, Luyten, Jan A.F.M., van der Burgt, Ineke J.A.M., de Groot, Ronald, Smeets, Dominique F.C.M., Draaisma, Jos M.T., van Dongen, Jacques J., De Abreu, Ronney A., Pearson, Peter L., Sandkuijl, Lodewijk A., Weemaes, Corry M.R.

Volltext

Real-Time Analysis of Tyrosine Hydroxylase Gene Expression von Lambert H. J. Lambooy, Corrie E. M. Gidding, Lambert P. van den Heuvel, Christina A. Hulsbergen-van de Kaa, Marjolijn Ligtenberg, Jos P. M. Bökkerink, Ronney A. De Abreu

Volltext

6-Mercaptopurine: Cytotoxicity and biochemical pharmacology in human malignant T-lymphoblasts von Bökkerink, Jos P.M., Stet, Elisabet H., De Abreu, Ronney A., Damen, Frank J.M., Hulscher, Tilly W., Bakker, Marinka A.H., Van Baal, John A.

Volltext

Azathioprine‐related bone marrow toxicity and low activities of purine enzymes in patients with rheumatoid arthritis von Kerstens, Pit J. S. M., Stolk, Jan N., De Abreu, Ronney A., Lambooy, Lambert H. J., Van Putte, Leo B. A. De, Boerbooms, Agnes A. M. T.

Volltext

Hemodynamic and neurohumoral effects of various grades of selective adenosine transport inhibition in humans. Implications for its future role in cardioprotection von Rongen, G A, Smits, P, Ver Donck, K, Willemsen, J J, De Abreu, R A, Van Belle, H, Thien, T

Volltext