T Cell Subset and Stimulation Strength-Dependent Modulation of T Cell Activation by Kv1.3 Blockers von Fung-Leung, Wai-Ping, Edwards, Wilson, Liu, Yi, Ngo, Karen, Angsana, Julianty, Castro, Glenda, Wu, Nancy, Liu, Xuejun, Swanson, Ronald V, Wickenden, Alan D

Volltext

Structural Basis for Bisphosphonate-mediated Inhibition of Isoprenoid Biosynthesis von Hosfield, David J., Zhang, Yanming, Dougan, Douglas R., Broun, Alexei, Tari, Leslie W., Swanson, Ronald V., Finn, John

Volltext

Conjugation of a peptide to an antibody engineered with free cysteines dramatically improves half-life and activity von Camacho, Raul C., You, Seohee, D’Aquino, Katharine E., Li, Wenyu, Wang, Yuanping, Gunnet, Joseph, Littrell, James, Qi, Jian Shen, Kang, Lijuan, Jian, Wenying, MacDonald, Mary, Tat, Timothy, Steiner, Derek, Zhang, Yue-Mei, Lanter, James, Patch, Raymond, Zhang, Rui, Li, Jiali, Edavettal, Suzanne, Edwards, Wilson, Dinh, Thai, Wang, Li Ying, Connor, Judy, Hunter, Michael, Chi, Ellen, Swanson, Ronald V., Leonard, James N., Case, Martin A.

Volltext

The complete genome of the hyperthermophilic bacterium Aquifex aeolicus von Huber, Robert, Swanson, Ronald V, Deckert, Gerard, Warren, Patrick V, Gaasterland, Terry, Young, William G, Lenox, Anna L, Graham, David E, Overbeek, Ross, Snead, Marjory A, Keller, Martin, Aujay, Monette, Feldman, Robert A, Short, Jay M, Olsen, Gary J

Volltext

A Long-Acting PYY3–36 Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates von Rangwala, Shamina M., D’Aquino, Katharine, Zhang, Yue-Mei, Bader, Lindsay, Edwards, Wilson, Zheng, Songmao, Eckardt, Annette, Lacombe, Ann, Pick, Rebecca, Moreno, Veronica, Kang, Lijuan, Jian, Wenying, Arnoult, Eric, Case, Martin, Jenkinson, Celia, Chi, Ellen, Swanson, Ronald V., Kievit, Paul, Grove, Kevin, Macielag, Mark, Erion, Mark D., SinhaRoy, Ranabir, Leonard, James N.

Volltext

Structures of the Cancer-Related Aurora-A, FAK, and EphA2 Protein Kinases from Nanovolume Crystallography von Nowakowski, Jacek, Cronin, Ciarán N., McRee, Duncan E., Knuth, Mark W., Nelson, Christian G., Pavletich, Nikola P., Rogers, Joe, Sang, Bi-Ching, Scheibe, Daniel N., Swanson, Ronald V., Thompson, Devon A.

Volltext

Comparative Genomic Analysis of Archaeal Genotypic Variants in a Single Population and in Two Different Oceanic Provinces von BEJA, Oded, KOONIN, Eugene V, ARAVIND, L, TAYLOR, Lance T, SEITZ, Heidi, STEIN, Jefferey L, BENSEN, Daniel C, FELDMAN, Robert A, SWANSON, Ronald V, DELONG, Edward F

Volltext

A Long-Acting PYY 3-36 Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates von Rangwala, Shamina M, D'Aquino, Katharine, Zhang, Yue-Mei, Bader, Lindsay, Edwards, Wilson, Zheng, Songmao, Eckardt, Annette, Lacombe, Ann, Pick, Rebecca, Moreno, Veronica, Kang, Lijuan, Jian, Wenying, Arnoult, Eric, Case, Martin, Jenkinson, Celia, Chi, Ellen, Swanson, Ronald V, Kievit, Paul, Grove, Kevin, Macielag, Mark, Erion, Mark D, SinhaRoy, Ranabir, Leonard, James N

Volltext

Discovery of TYRA-300: First Oral Selective FGFR3 Inhibitor for the Treatment of Urothelial Cancers and Achondroplasia von Hudkins, Robert L., Allen, Eric, Balcer, Alexandra, Hoffman, Isaac D., Iyer, Samhita, Neal, Melissa, Nelson, Kirk J., Rideout, Marc, Ye, Qing, Starrett, Jacqueline H., Patel, Piyush, Harris, Todd, Swanson, Ronald V., Bensen, Daniel C.

Volltext

Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases von Somoza, John R, Skene, Robert J, Katz, Bradley A, Mol, Clifford, Ho, Joseph D, Jennings, Andy J, Luong, Christine, Arvai, Andrew, Buggy, Joseph J, Chi, Ellen, Tang, Jie, Sang, Bi-Ching, Verner, Erik, Wynands, Robert, Leahy, Ellen M, Dougan, Douglas R, Snell, Gyorgy, Navre, Marc, Knuth, Mark W, Swanson, Ronald V, McRee, Duncan E, Tari, Leslie W

Volltext

N‐linked glycosylation of dipeptidyl peptidase IV (CD26): Effects on enzyme activity, homodimer formation, and adenosine deaminase binding von Aertgeerts, Kathleen, Ye, Sheng, Shi, Lihong, Prasad, Sridhar G., Witmer, Darbi, Chi, Ellen, Sang, Bi‐Ching, Wijnands, Robert A., Webb, David R., Swanson, Ronald V.

Volltext

Crystal Structures of Active Fully Assembled Substrate- and Product-Bound Complexes of UDP-N-Acetylmuramic Acid:l-Alanine Ligase (MurC) from Haemophilus influenzae von Mol, Clifford D, Brooun, Alexei, Dougan, Douglas R, Hilgers, Mark T, Tari, Leslie W, Wijnands, Robert A, Knuth, Mark W, McRee, Duncan E, Swanson, Ronald V

Volltext

The Crystal Structure of Shikimate Dehydrogenase (AroE) Reveals a Unique NADPH Binding Mode von Ye, Sheng, Von Delft, Frank, Brooun, Alexei, Knuth, Mark W, Swanson, Ronald V, McRee, Duncan E

Volltext

Targeting the Ion Channel Kv1.3 with Scorpion Venom Peptides Engineered for Potency, Selectivity, and Half-life von Edwards, Wilson, Fung-Leung, Wai-Ping, Huang, Chichi, Chi, Ellen, Wu, Nancy, Liu, Yi, Maher, Michael P., Bonesteel, Rachelle, Connor, Judith, Fellows, Ross, Garcia, Elena, Lee, Jerry, Lu, Lu, Ngo, Karen, Scott, Brian, Zhou, Hong, Swanson, Ronald V., Wickenden, Alan D.

Volltext

The genome of M. acetivorans reveals extensive metabolic and physiological diversity von Galagan, James E, Nusbaum, Chad, Roy, Alice, Endrizzi, Matthew G, Macdonald, Pendexter, FitzHugh, Will, Calvo, Sarah, Engels, Reinhard, Smirnov, Serge, Atnoor, Deven, Brown, Adam, Allen, Nicole, Naylor, Jerome, Stange-Thomann, Nicole, DeArellano, Kurt, Johnson, Robin, Linton, Lauren, McEwan, Paul, McKernan, Kevin, Talamas, Jessica, Tirrell, Andrea, Ye, Wenjuan, Zimmer, Andrew, Barber, Robert D, Cann, Isaac, Graham, David E, Grahame, David A, Guss, Adam M, Hedderich, Reiner, Ingram-Smith, Cheryl, Kuettner, H Craig, Krzycki, Joseph A, Leigh, John A, Li, Weixi, Liu, Jinfeng, Mukhopadhyay, Biswarup, Reeve, John N, Smith, Kerry, Springer, Timothy A, Umayam, Lowell A, White, Owen, White, Robert H, Conway de Macario, Everly, Ferry, James G, Jarrell, Ken F, Jing, Hua, Macario, Alberto J L, Paulsen, Ian, Pritchett, Matthew, Sowers, Kevin R, Swanson, Ronald V, Zinder, Steven H, Lander, Eric, Metcalf, William W, Birren, Bruce

Volltext

Assembly and function of a quaternary signal transduction complex monitored by surface plasmon resonance von Schuster, Stephan C, Swanson, Ronald V, Alex, Lisa A, Bourret, Robert B, Simon, Melvin I

Volltext

Characterization of a high-affinity human antibody with a disulfide bridge in the third complementarity-determining region of the heavy chain von Almagro, Juan Carlos, Raghunathan, Gopalan, Beil, Eric, Janecki, Dariusz J., Chen, Qiang, Dinh, Thai, LaCombe, Ann, Connor, Judy, Ware, Mark, Kim, Paul H., Swanson, Ronald V., Fransson, Johan

Volltext

Human Framework Adaptation of a Mouse Anti-Human IL-13 Antibody von Fransson, Johan, Teplyakov, Alexey, Raghunathan, Gopalan, Chi, Ellen, Cordier, Wendy, Dinh, Thai, Feng, Yiqing, Giles-Komar, Jill, Gilliland, Gary, Lollo, Bridget, Malia, Thomas J., Nishioka, Walter, Obmolova, Galina, Zhao, Shanrong, Zhao, Yonghong, Swanson, Ronald V., Almagro, Juan C.

Volltext

Molecular Cloning and Functional Expression of a Protein-Serine/Threonine Phosphatase from the Hyperthermophilic Archaeon Pyrodictium abyssi TAG11 von Mai, B, Frey, G, Swanson, R V, Mathur, E J, Stetter, K O

Volltext

The solution structure and interactions of CheW from Thermotoga maritima von Dahlquist, Frederick W, Griswold, Ian J, Zhou, Hongjun, Matison, Mikenzie, Swanson, Ronald V, McIntosh, Lawrence P, Simon, Melvin I

Volltext