Regulators of mitochondrial dynamics in cancer von Senft, Daniela, Ronai, Ze’ev A

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Fine-Tuning of Drp1/Fis1 Availability by AKAP121/Siah2 Regulates Mitochondrial Adaptation to Hypoxia von Kim, Hyungsoo, Scimia, Maria C., Wilkinson, Deepti, Trelles, Ramon D., Wood, Malcolm R., Bowtell, David, Dillin, Andrew, Mercola, Mark, Ronai, Ze'ev A.

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The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors von Khateb, Ali, Deshpande, Anagha, Feng, Yongmei, Finlay, Darren, Lee, Joo Sang, Lazar, Ikrame, Fabre, Bertrand, Li, Yan, Fujita, Yu, Zhang, Tongwu, Yin, Jun, Pass, Ian, Livneh, Ido, Jeremias, Irmela, Burian, Carol, Mason, James R., Almog, Ronit, Horesh, Nurit, Ofran, Yishai, Brown, Kevin, Vuori, Kristiina, Jackson, Michael, Ruppin, Eytan, Deshpande, Aniruddha J., Ronai, Ze’ev A.

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Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons von Welsbie, Derek S., Mitchell, Katherine L., Jaskula-Ranga, Vinod, Sluch, Valentin M., Yang, Zhiyong, Kim, Jessica, Buehler, Eugen, Patel, Amit, Martin, Scott E., Zhang, Ping-Wu, Ge, Yan, Duan, Yukan, Fuller, John, Kim, Byung-Jin, Hamed, Eman, Chamling, Xitiz, Lei, Lei, Fraser, Iain D.C., Ronai, Ze’ev A., Berlinicke, Cynthia A., Zack, Donald J.

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ATF2 - at the crossroad of nuclear and cytosolic functions von Lau, Eric, Ronai, Ze'ev A

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The gut microbiome: an unexpected player in cancer immunity von Peterson, Scott N, Bradley, Linda M, Ronai, Ze’ev A

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Melanoma models for the next generation of therapies von Patton, E. Elizabeth, Mueller, Kristen L., Adams, David J., Anandasabapathy, Niroshana, Aplin, Andrew E., Bertolotto, Corine, Bosenberg, Marcus, Ceol, Craig J., Burd, Christin E., Chi, Ping, Herlyn, Meenhard, Holmen, Sheri L., Karreth, Florian A., Kaufman, Charles K., Khan, Shaheen, Kobold, Sebastian, Leucci, Eleonora, Levy, Carmit, Lombard, David B., Lund, Amanda W., Marie, Kerrie L., Marine, Jean-Christophe, Marais, Richard, McMahon, Martin, Robles-Espinoza, Carla Daniela, Ronai, Ze'ev A., Samuels, Yardena, Soengas, Maria S., Villanueva, Jessie, Weeraratna, Ashani T., White, Richard M., Yeh, Iwei, Zhu, Jiyue, Zon, Leonard I., Hurlbert, Marc S., Merlino, Glenn

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Siah2-Dependent Concerted Activity of HIF and FoxA2 Regulates Formation of Neuroendocrine Phenotype and Neuroendocrine Prostate Tumors von Qi, Jianfei, Nakayama, Koh, Cardiff, Robert D., Borowsky, Alexander D., Kaul, Karen, Williams, Roy, Krajewski, Stan, Mercola, Dan, Carpenter, Philip M., Bowtell, David, Ronai, Ze'ev A.

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Ubiquitin ligases in oncogenic transformation and cancer therapy von Senft, Daniela, Qi, Jianfei, Ronai, Ze'ev A.

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Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice von Li, Yan, Tinoco, Roberto, Elmén, Lisa, Segota, Igor, Xian, Yibo, Fujita, Yu, Sahu, Avinash, Zarecki, Raphy, Marie, Kerrie, Feng, Yongmei, Khateb, Ali, Frederick, Dennie T., Ashkenazi, Shiri K., Kim, Hyungsoo, Perez, Eva Guijarro, Day, Chi-Ping, Segura Muñoz, Rafael S., Schmaltz, Robert, Yooseph, Shibu, Tam, Miguel A., Zhang, Tongwu, Avitan-Hersh, Emily, Tzur, Lihi, Roizman, Shoshana, Boyango, Ilanit, Bar-Sela, Gil, Orian, Amir, Kaufman, Randal J., Bosenberg, Marcus, Goding, Colin R., Baaten, Bas, Levesque, Mitchell P., Dummer, Reinhard, Brown, Kevin, Merlino, Glenn, Ruppin, Eytan, Flaherty, Keith, Ramer-Tait, Amanda, Long, Tao, Peterson, Scott N., Bradley, Linda M., Ronai, Ze’ev A.

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UPR, autophagy, and mitochondria crosstalk underlies the ER stress response von Senft, Daniela, Ronai, Ze’ev A.

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SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation von Jiang, Tian-Xia, Zou, Jiang-Bo, Zhu, Qian-Qian, Liu, Cui Hua, Wang, Guang-Fei, Du, Ting-Ting, Luo, Zi-Yu, Guo, Fang, Zhou, Lu-Ming, Liu, Juan-Juan, Zhang, Wensheng, Shu, You-Sheng, Yu, Li, Li, Peng, Ronai, Ze’ev A., Matsuzawa, Shu-ichi, Goldberg, Alfred L., Qiu, Xiao-Bo

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PKCε Promotes Oncogenic Functions of ATF2 in the Nucleus while Blocking Its Apoptotic Function at Mitochondria von Lau, Eric, Kluger, Harriet, Varsano, Tal, Lee, KiYoung, Scheffler, Immo, Rimm, David L., Ideker, Trey, Ronai, Ze'ev A.

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Targeting eIF4F translation initiation complex with SBI-756 sensitises B lymphoma cells to venetoclax von Herzog, Lee-or, Walters, Beth, Buono, Roberta, Lee, J. Scott, Mallya, Sharmila, Fung, Amos, Chiu, Honyin, Nguyen, Nancy, Li, Boyang, Pinkerton, Anthony B., Jackson, Michael R., Schneider, Robert J., Ronai, Ze’ev A., Fruman, David A.

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Translational Homeostasis via the mRNA Cap-Binding Protein, eIF4E von Yanagiya, Akiko, Suyama, Eigo, Adachi, Hironori, Svitkin, Yuri V., Aza-Blanc, Pedro, Imataka, Hiroaki, Mikami, Satoshi, Martineau, Yvan, Ronai, Ze'ev A., Sonenberg, Nahum

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PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets von Scortegagna, Marzia, Lau, Eric, Zhang, Tongwu, Feng, Yongmei, Sereduk, Chris, Yin, Hongwei, De, Surya K, Meeth, Katrina, Platt, James T, Langdon, Casey G, Halaban, Ruth, Pellecchia, Maurizio, Davies, Michael A, Brown, Kevin, Stern, David F, Bosenberg, Marcus, Ronai, Ze'ev A

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SPANX Control of Lamin A/C Modulates Nuclear Architecture and Promotes Melanoma Growth von Lazar, Ikrame, Fabre, Bertrand, Feng, Yongmei, Khateb, Ali, Turko, Patrick, Gomez, Julia M. Martinez, Frederick, Dennie T., Levesque, Mitchell P., Feld, Lea, Zhang, Gao, Zhang, Tongwu, James, Brian, Shklover, Jeny, Avitan-Hersh, Emily, Livneh, Ido, Scortegagna, Marzia, Brown, Kevin, Larsson, Ola, Topisirovic, Ivan, Wolfenson, Haguy, Herlyn, Meenhard, Flaherty, Keith, Dummer, Reinhard, Ronai, Ze'ev A.

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Ubiquitin-recognition protein Ufd1 couples the endoplasmic reticulum (ER) stress response to cell cycle control von Chen, Meifan, Gutierrez, Gustavo J, Ronai, Ze'ev A

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Preclinical Studies of Celastrol and Acetyl Isogambogic Acid in Melanoma von ABBAS, Sabiha, BHOUMIK, Anindita, DAHL, Russell, VASILE, Stefan, KRAJEWSKI, Stan, COSFORD, Nicholas D. P, RONAI, Zeev A

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Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance von Liu, Jianglan, Rebecca, Vito W., Kossenkov, Andrew, Connelly, Thomas, Liu, Qin, Gutierrez, Alexis, Xiao, Min, Li, Ling, Zhang, Gao, Samarkina, Anastasia, Zayasbazan, Delaine, Zhang, Jie, Cheng, Chaoran, Wei, Zhi, Alicea, Gretchen M., Fukunaga-Kalabis, Mizuho, Krepler, Clemens, Aza-Blanc, Pedro, Yang, Chih-Cheng, Delvadia, Bela, Tong, Cynthia, Huang, Ye, Delvadia, Maya, Morias, Alice S., Sproesser, Katrin, Brafford, Patricia, Wang, Joshua X., Beqiri, Marilda, Somasundaram, Rajasekharan, Vultur, Adina, Hristova, Denitsa M., Wu, Lawrence W., Lu, Yiling, Mills, Gordon B., Xu, Wei, Karakousis, Giorgos C., Xu, Xiaowei, Schuchter, Lynn M., Mitchell, Tara C., Amaravadi, Ravi K., Kwong, Lawrence N., Frederick, Dennie T., Boland, Genevieve M., Salvino, Joseph M., Speicher, David W., Flaherty, Keith T., Ronai, Ze'ev A., Herlyn, Meenhard

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