Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study von Hainsworth, John D, Meric-Bernstam, Funda, Swanton, Charles, Hurwitz, Herbert, Spigel, David R, Sweeney, Christopher, Burris, Howard, Bose, Ron, Yoo, Bongin, Stein, Alisha, Beattie, Mary, Kurzrock, Razelle

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Pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer (MyPathway): an updated report from a multicentre, open-label, phase 2a, multiple basket study von Meric-Bernstam, Funda, Hurwitz, Herbert, Raghav, Kanwal Pratap Singh, McWilliams, Robert R, Fakih, Marwan, VanderWalde, Ari, Swanton, Charles, Kurzrock, Razelle, Burris, Howard, Sweeney, Christopher, Bose, Ron, Spigel, David R, Beattie, Mary S, Blotner, Steven, Stone, Alyssa, Schulze, Katja, Cuchelkar, Vaikunth, Hainsworth, John

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Pertuzumab and trastuzumab for HER2-positive, metastatic biliary tract cancer (MyPathway): a multicentre, open-label, phase 2a, multiple basket study von Javle, Milind, Borad, Mitesh J, Azad, Nilofer S, Kurzrock, Razelle, Abou-Alfa, Ghassan K, George, Ben, Hainsworth, John, Meric-Bernstam, Funda, Swanton, Charles, Sweeney, Christopher J, Friedman, Claire F, Bose, Ron, Spigel, David R, Wang, Yong, Levy, Jonathan, Schulze, Katja, Cuchelkar, Vaikunth, Patel, Arisha, Burris, Howard

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CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer von Griffith, Malachi, Spies, Nicholas C, Krysiak, Kilannin, McMichael, Joshua F, Coffman, Adam C, Danos, Arpad M, Ainscough, Benjamin J, Ramirez, Cody A, Rieke, Damian T, Kujan, Lynzey, Barnell, Erica K, Wagner, Alex H, Skidmore, Zachary L, Wollam, Amber, Liu, Connor J, Jones, Martin R, Bilski, Rachel L, Lesurf, Robert, Feng, Yan-Yang, Shah, Nakul M, Bonakdar, Melika, Trani, Lee, Matlock, Matthew, Ramu, Avinash, Campbell, Katie M, Spies, Gregory C, Graubert, Aaron P, Gangavarapu, Karthik, Eldred, James M, Larson, David E, Walker, Jason R, Good, Benjamin M, Wu, Chunlei, Su, Andrew I, Dienstmann, Rodrigo, Margolin, Adam A, Tamborero, David, Lopez-Bigas, Nuria, Jones, Steven J M, Bose, Ron, Spencer, David H, Wartman, Lukas D, Wilson, Richard K, Mardis, Elaine R, Griffith, Obi L

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Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers von Govindan, Ramaswamy, Ding, Li, Griffith, Malachi, Subramanian, Janakiraman, Dees, Nathan D., Kanchi, Krishna L., Maher, Christopher A., Fulton, Robert, Fulton, Lucinda, Wallis, John, Chen, Ken, Walker, Jason, McDonald, Sandra, Bose, Ron, Ornitz, David, Xiong, Donghai, You, Ming, Dooling, David J., Watson, Mark, Mardis, Elaine R., Wilson, Richard K.

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HER2 activating mutations are targets for colorectal cancer treatment von Kavuri, Shyam M, Jain, Naveen, Galimi, Francesco, Cottino, Francesca, Leto, Simonetta M, Migliardi, Giorgia, Searleman, Adam C, Shen, Wei, Monsey, John, Trusolino, Livio, Jacobs, Samuel A, Bertotti, Andrea, Bose, Ron

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Genomic Characterization of Primary Invasive Lobular Breast Cancer von Desmedt, Christine, Zoppoli, Gabriele, Gundem, Gunes, Pruneri, Giancarlo, Larsimont, Denis, Fornili, Marco, Fumagalli, Debora, Brown, David, Rothé, Françoise, Vincent, Delphine, Kheddoumi, Naima, Rouas, Ghizlane, Majjaj, Samira, Brohée, Sylvain, Van Loo, Peter, Maisonneuve, Patrick, Salgado, Roberto, Van Brussel, Thomas, Lambrechts, Diether, Bose, Ron, Metzger, Otto, Galant, Christine, Bertucci, François, Piccart-Gebhart, Martine, Viale, Giuseppe, Biganzoli, Elia, Campbell, Peter J, Sotiriou, Christos

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Activating HER2 mutations in HER2 gene amplification negative breast cancer von Bose, Ron, Kavuri, Shyam M, Searleman, Adam C, Shen, Wei, Shen, Dong, Koboldt, Daniel C, Monsey, John, Goel, Nicholas, Aronson, Adam B, Li, Shunqiang, Ma, Cynthia X, Ding, Li, Mardis, Elaine R, Ellis, Matthew J

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Whole-genome analysis informs breast cancer response to aromatase inhibition von Ellis, Matthew J., Ding, Li, Shen, Dong, Luo, Jingqin, Suman, Vera J., Wallis, John W., Van Tine, Brian A., Hoog, Jeremy, Goiffon, Reece J., Goldstein, Theodore C., Ng, Sam, Lin, Li, Crowder, Robert, Snider, Jacqueline, Ballman, Karla, Weber, Jason, Chen, Ken, Koboldt, Daniel C., Kandoth, Cyriac, Schierding, William S., McMichael, Joshua F., Miller, Christopher A., Lu, Charles, Harris, Christopher C., McLellan, Michael D., Wendl, Michael C., DeSchryver, Katherine, Allred, D. Craig, Esserman, Laura, Unzeitig, Gary, Margenthaler, Julie, Babiera, G. V., Marcom, P. Kelly, Guenther, J. M., Leitch, Marilyn, Hunt, Kelly, Olson, John, Tao, Yu, Maher, Christopher A., Fulton, Lucinda L., Fulton, Robert S., Harrison, Michelle, Oberkfell, Ben, Du, Feiyu, Demeter, Ryan, Vickery, Tammi L., Elhammali, Adnan, Piwnica-Worms, Helen, McDonald, Sandra, Watson, Mark, Dooling, David J., Ota, David, Chang, Li-Wei, Bose, Ron, Ley, Timothy J., Piwnica-Worms, David, Stuart, Joshua M., Wilson, Richard K., Mardis, Elaine R.

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Neratinib Efficacy and Circulating Tumor DNA Detection of HER2 Mutations in HER2 Nonamplified Metastatic Breast Cancer von Ma, Cynthia X, Bose, Ron, Gao, Feng, Freedman, Rachel A, Telli, Melinda L, Kimmick, Gretchen, Winer, Eric, Naughton, Michael, Goetz, Matthew P, Russell, Christy, Tripathy, Debu, Cobleigh, Melody, Forero, Andres, Pluard, Timothy J, Anders, Carey, Niravath, Polly Ann, Thomas, Shana, Anderson, Jill, Bumb, Caroline, Banks, Kimberly C, Lanman, Richard B, Bryce, Richard, Lalani, Alshad S, Pfeifer, John, Hayes, Daniel F, Pegram, Mark, Blackwell, Kimberly, Bedard, Philippe L, Al-Kateb, Hussam, Ellis, Matthew J C

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Endocrine-Therapy-Resistant ESR1 Variants Revealed by Genomic Characterization of Breast-Cancer-Derived Xenografts von Li, Shunqiang, Shen, Dong, Shao, Jieya, Crowder, Robert, Liu, Wenbin, Prat, Aleix, He, Xiaping, Liu, Shuying, Hoog, Jeremy, Lu, Charles, Ding, Li, Griffith, Obi L., Miller, Christopher, Larson, Dave, Fulton, Robert S., Harrison, Michelle, Mooney, Tom, McMichael, Joshua F., Luo, Jingqin, Tao, Yu, Goncalves, Rodrigo, Schlosberg, Christopher, Hiken, Jeffrey F., Saied, Laila, Sanchez, Cesar, Giuntoli, Therese, Bumb, Caroline, Cooper, Crystal, Kitchens, Robert T., Lin, Austin, Phommaly, Chanpheng, Davies, Sherri R., Zhang, Jin, Kavuri, Megha Shyam, McEachern, Donna, Dong, Yi Yu, Ma, Cynthia, Pluard, Timothy, Naughton, Michael, Bose, Ron, Suresh, Rama, McDowell, Reida, Michel, Loren, Aft, Rebecca, Gillanders, William, DeSchryver, Katherine, Wilson, Richard K., Wang, Shaomeng, Mills, Gordon B., Gonzalez-Angulo, Ana, Edwards, John R., Maher, Christopher, Perou, Charles M., Mardis, Elaine R., Ellis, Matthew J.

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The prognostic effects of somatic mutations in ER-positive breast cancer von Griffith, Obi L., Spies, Nicholas C., Anurag, Meenakshi, Griffith, Malachi, Luo, Jingqin, Tu, Dongsheng, Yeo, Belinda, Kunisaki, Jason, Miller, Christopher A, Krysiak, Kilannin, Hundal, Jasreet, Ainscough, Benjamin J, Skidmore, Zachary L., Campbell, Katie, Kumar, Runjun, Fronick, Catrina, Cook, Lisa, Snider, Jacqueline E., Davies, Sherri, Kavuri, Shyam M., Chang, Eric C., Magrini, Vincent, Larson, David E., Fulton, Robert S, Liu, Shuzhen, Leung, Samuel, Voduc, David, Bose, Ron, Dowsett, Mitch, Wilson, Richard K., Nielsen, Torsten O., Mardis, Elaine R, Ellis, Matthew J.

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Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface von Pickin, Kerry A, Jura, Natalia, Cole, Philip A, Bose, Ron, Kuriyan, John, Zhang, Xuewu

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Sacituzumab-govitecan-induced severe acute tubulointerstitial nephritis requiring hemodialysis von Guarin, Geneva, Netzel, Audrey, Flores, Karen Marie, Cumpelik, Arun, Bose, Ron

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Analysis of somatic mutations across the kinome reveals loss-of-function mutations in multiple cancer types von Kumar, Runjun D., Bose, Ron

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Environmental impact improvements due to introducing automation into underground copper mines von Moreau, Kyle, Laamanen, Corey, Bose, Ron, Shang, Helen, Scott, John Ashley

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Nonamplification ERBB2 genomic alterations in 5605 cases of recurrent and metastatic breast cancer: An emerging opportunity for anti‐HER2 targeted therapies von Ross, Jeffrey S., Gay, Laurie M., Wang, Kai, Ali, Siraj M., Chumsri, Saranya, Elvin, Julia A., Bose, Ron, Vergilio, Jo‐Anne, Suh, James, Yelensky, Roman, Lipson, Doron, Chmielecki, Juliann, Waintraub, Stanley, Leyland‐Jones, Brian, Miller, Vincent A., Stephens, Philip J.

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Immunogenomic profiling and pathological response results from a clinical trial of docetaxel and carboplatin in triple-negative breast cancer von Ademuyiwa, Foluso O., Chen, Ina, Luo, Jingqin, Rimawi, Mothaffar F., Hagemann, Ian S., Fisk, Bryan, Jeffers, Gejae, Skidmore, Zachary L., Basu, Anamika, Richters, Megan, Ma, Cynthia X., Weilbaecher, Katherine, Davis, Jennifer, Suresh, Rama, Peterson, Lindsay L., Bose, Ron, Bagegni, Nusayba, Rigden, Caron E., Frith, Ashley, Rearden, Timothy P., Hernandez-Aya, Leonel F., Roshal, Anna, Clifton, Katherine, Opyrchal, Mateusz, Akintola-Ogunremi, Olaronke, Lee, Byung Ha, Ferrando-Martinez, Sara, Church, Sarah E., Anurag, Meenakshi, Ellis, Matthew J., Gao, Feng, Gillanders, William, Griffith, Obi L., Griffith, Malachi

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Her4 and Her2/neu Tyrosine Kinase Domains Dimerize and Activate in a Reconstituted in Vitro System von Monsey, John, Shen, Wei, Schlesinger, Paul, Bose, Ron

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Biophysical Evidence for Intrinsic Disorder in the C-terminal Tails of the Epidermal Growth Factor Receptor (EGFR) and HER3 Receptor Tyrosine Kinases von Keppel, Theodore R., Sarpong, Kwabena, Murray, Elisa M., Monsey, John, Zhu, Jian, Bose, Ron

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