Preliminary Results of a Trial of Atabecestat in Preclinical Alzheimer’s Disease von Henley, David, Raghavan, Nandini, Sperling, Reisa, Aisen, Paul, Raman, Rema, Romano, Gary

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Genome-wide association study of abnormal elevation of ALT in patients exposed to atabecestat von Li, Qingqin S, Francke, Stephan, Snoeys, Jan, Thipphawong, John, Romano, Gary, Novak, Gerald P

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Targeting Progranulin as an Immuno-Neurology Therapeutic Approach von Boylan, Maria A, Pincetic, Andrew, Romano, Gary, Tatton, Nadine, Kenkare-Mitra, Sara, Rosenthal, Arnon

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The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable von Knopman, David S., Haeberlein, Samantha Budd, Carrillo, Maria C., Hendrix, James A., Kerchner, Geoff, Margolin, Richard, Maruff, Paul, Miller, David S., Tong, Gary, Tome, Maria B., Murray, Melissa E., Nelson, Peter T., Sano, Mary, Mattsson, Niklas, Sultzer, David L., Montine, Thomas J., Jack, Clifford R., Kolb, Hartmuth, Petersen, Ronald C., Vemuri, Prashanthi, Canniere, Megan Zoschg, Schneider, Julie A., Resnick, Susan M., Romano, Gary, van Harten, Argonde Corien, Wolk, David A., Bain, Lisa J., Siemers, Eric

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TRPV1 antagonist JNJ-39439335 (mavatrep) demonstrates proof of pharmacology in healthy men: a first-in-human, double-blind, placebo-controlled, randomized, sequential group study von Manitpisitkul, Prasarn, Brandt, Michael, Flores, Christopher M., Kenigs, Velga, Moyer, John A., Romano, Gary, Shalayda, Kevin, Mayorga, Arthur J.

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Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial von Sperling, Reisa, Henley, David, Aisen, Paul S, Raman, Rema, Donohue, Michael C, Ernstrom, Karin, Rafii, Michael S, Streffer, Johannes, Shi, Yingqi, Karcher, Keith, Raghavan, Nandini, Tymofyeyev, Yevgen, Bogert, Jennifer, Brashear, H. Robert, Novak, Gerald, Thipphawong, John, Saad, Ziad S, Kolb, Hartmuth, Rofael, Hany, Sanga, Panna, Romano, Gary

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INVOKE‐2: Phase 2 trial of a TREM2 mAb in Early AD von Romano, Gary, Mayorga, Arthur, Simmons, Adam, Burgess, Brady, Grundman, Michael, Gao, Jinjing

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SCN9A Variants May be Implicated in Neuropathic Pain Associated With Diabetic Peripheral Neuropathy and Pain Severity von Li, Qingqin S, Cheng, Peter, Favis, Reyna, Wickenden, Alan, Romano, Gary, Wang, Hao

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Views and perceptions of amyloid imaging in a preclinical Alzheimer’s disease trial von Ritchie, Marina, Raman, Rema, Ernstrom, Karin, Wang, Shunran, Donohue, Michael C., Aisen, Paul S. S, Henley, David, Romano, Gary, Novak, Gerald P, Brashear, H. Robert, Sperling, Reisa A., Grill, Joshua D.

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Impact of cerebrospinal fluid matrix on the detection of Alzheimer's disease with Aβ42 and influence of disease on the total‐Aβ42/Aβ40 ratio von Slemmon, J. Randall, Shapiro, Alice, Mercken, Marc, Streffer, Johannes, Romano, Gary, Andreasen, Niels, Zetterberg, Henrik, Blennow, Kaj

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Fulranumab for treatment of diabetic peripheral neuropathic pain: A randomized controlled trial von Wang, Hao, Romano, Gary, Frustaci, Mary Ellen, Bohidar, Norm, Ma, Huizhong, Sanga, Panna, Ness, Seth, Russell, Lucille J, Fedgchin, Margaret, Kelly, Kathleen M, Thipphawong, John

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Fulranumab in Patients With Pain Associated With Postherpetic Neuralgia and Postraumatic Neuropathy: Efficacy, Safety, and Tolerability Results From a Randomized, Double-blind, Pla... von Wang, Hao, Romano, Gary, Fedgchin, Margaret, Russell, Lucille, Sanga, Panna, Kelly, Kathleen M, Frustaci, Mary Ellen, Thipphawong, John

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Impact of cerebrospinal fluid matrix on the detection of Alzheimer's disease with A beta 42 and influence of disease on the total-A beta 42/A beta 40 ratio von Slemmon, JRandall, Shapiro, Alice, Mercken, Marc, Streffer, Johannes, Romano, Gary, Andreasen, Niels, Zetterberg, Henrik, Blennow, Kaj

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Sensitivity of the Preclinical Alzheimer’s Cognitive Composite (PACC), PACC5, and Repeatable Battery for Neuropsychological Status (RBANS) to Amyloid Status in Preclinical Alzheime... von Papp, Kathryn V., Rofael, H., Veroff, A. E., Donohue, M. C., Wang, S., Randolph, C., Grober, E., Brashear, H. Robert, Novak, G., Ernstrom, K., Raman, R., Aisen, P. S., Sperling, R., Romano, Gary, Henley, David

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A multiple-dose double-blind randomized study to evaluate the safety, pharmacokinetics, pharmacodynamics and analgesic efficacy of the TRPV1 antagonist JNJ-39439335 (mavatrep) von Manitpisitkul, Prasarn, Flores, Christopher M., Moyer, John A., Romano, Gary, Shalayda, Kevin, Tatikola, Kanaka, Hutchison, James S., Mayorga, Arthur J.

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Immediate Reactions to Alzheimer Biomarker Disclosure in Cognitively Unimpaired Individuals in a Global Truncated Randomized Trial von Grill, Joshua D, Raman, Rema, Ernstrom, Karin, Wang, Shunran, Donohue, Michael C, Aisen, Paul S, Karlawish, Jason, Henley, David, Romano, Gary, Novak, Gerald, Brashear, H Robert, Sperling, Reisa A

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Impact of cerebrospinal fluid matrix on the detection of Alzheimer's disease with A[beta]42 and influence of disease on the total-A[beta]42/A[beta]40 ratio von Slemmon, J Randall, Shapiro, Alice, Mercken, Marc, Streffer, Johannes, Romano, Gary, Andreasen, Niels, Zetterberg, Henrik, Blennow, Kaj

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A randomized study to evaluate the analgesic efficacy of a single dose of the TRPV1 antagonist mavatrep in patients with osteoarthritis von Mayorga, Arthur J., Flores, Christopher M., Trudeau, Jeremiah J., Moyer, John A., Shalayda, Kevin, Dale, Mark, Frustaci, Mary Ellen, Katz, Nathaniel, Manitpisitkul, Prasarn, Treister, Roi, Ratcliffe, Stuart, Romano, Gary

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FTS3‐01‐04: FINAL EFFICACY, SAFETY AND BIOMARKER RESULTS OF THE PHASE 2B/3 RANDOMIZED, DOUBLE‐BLINDED, PLACEBO‐CONTROLLED EARLY TRIAL OF ATABECESTAT IN PRECLINICAL ALZHEIMER'S DISE... von Henley, David, Sperling, Reisa A., Aisen, Paul S., Raman, Rema, Donohue, Michael C., Ernstrom, Karin, Shi, Yingqi, Karcher, Keith, Raghavan, Nandini, Tymofyeyev, Yevgen, Brashear, Robert, Novak, Gerald P., Thipphawong, John, Saad, Ziad, Kolb, Hartmuth C., Romano, Gary

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FINAL EFFICACY, SAFETY AND BIOMARKER RESULTS OF THE PHASE 2B/3 RANDOMIZED, DOUBLE-BLINDED, PLACEBO-CONTROLLED EARLY TRIAL OF ATABECESTAT IN PRECLINICAL ALZHEIMER’S DISEASE von Henley, David, Sperling, Reisa A., Aisen, Paul S., Raman, Rema, Donohue, Michael C., Ernstrom, Karin, Shi, Yingqi, Karcher, Keith, Raghavan, Nandini, Tymofyeyev, Yevgen, Brashear, Robert, Novak, Gerald P., Thipphawong, John, Saad, Ziad, Kolb, Hartmuth C., Romano, Gary

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