Selective HCN1 block as a strategy to control oxaliplatin-induced neuropathy von Resta, F., Micheli, L., Laurino, A., Spinelli, V., Mello, T., Sartiani, L., Di Cesare Mannelli, L., Cerbai, E., Ghelardini, C., Romanelli, M.N., Mannaioni, G., Masi, A.

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Design, synthesis and preliminary biological evaluation of new hydroxamate histone deacetylase inhibitors as potential antileukemic agents von Guandalini, L., Cellai, C., Laurenzana, A., Scapecchi, S., Paoletti, F., Romanelli, M.N.

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Influence of ring size on the cognition-enhancing activity of DM235 and MN19, two potent nootropic drugs von Guandalini, L., Martini, E., Di Cesare Mannelli, L., Dei, S., Manetti, D., Scapecchi, S., Teodori, E., Ghelardini, C., Romanelli, M.N.

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WEB-2086 and WEB-2170 trigger apoptosis in both ATRA-sensitive and -resistant promyelocytic leukemia cells and greatly enhance ATRA differentiation potential von LAURENZANA, A, CELLAI, C, VANNUCCHI, A. M, PANCRAZZI, A, ROMANELLI, M. N, PAOLETTI, F

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Design, synthesis and preliminary evaluation of a series of histone deacetylase inhibitors carrying a benzodiazepine ring von Guandalini, L., Balliu, M., Cellai, C., Martino, M.V., Nebbioso, A., Mercurio, C., Carafa, V., Bartolucci, G., Dei, S., Manetti, D., Teodori, E., Scapecchi, S., Altucci, L., Paoletti, F., Romanelli, M.N.

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AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram) von Galeotti, N, Ghelardini, C, Pittaluga, A, Pugliese, A M, Bartolini, A, Manetti, D, Romanelli, M N, Gualtieri, F

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Design, Synthesis, and in Vitro Activity of Catamphiphilic Reverters of Multidrug Resistance:  Discovery of a Selective, Highly Efficacious Chemosensitizer with Potency in the Nano... von Teodori, Elisabetta, Dei, Silvia, Quidu, Patricia, Budriesi, Roberta, Chiarini, Alberto, Garnier-Suillerot, Arlette, Gualtieri, Fulvio, Manetti, Dina, Romanelli, Maria Novella, Scapecchi, Serena

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The new low‐toxic histone deacetylase inhibitor S‐(2) induces apoptosis in various acute myeloid leukaemia cells von Cellai, C., Balliu, M., Laurenzana, A., Guandalini, L., Matucci, R., Miniati, D., Torre, E., Nebbioso, A., Carafa, V., Altucci, L., Romanelli, M. N., Paoletti, F.

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Molecular Simplification of 1,4-Diazabicyclo[4.3.0]nonan-9-ones Gives Piperazine Derivatives That Maintain High Nootropic Activity von Manetti, Dina, Ghelardini, Carla, Bartolini, Alessandro, Dei, Silvia, Galeotti, Nicoletta, Gualtieri, Fulvio, Romanelli, Maria Novella, Teodori, Elisabetta

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Analgesic effects of myrrh von Dolara, Piero, Luceri, Cristina, Ghelardini, Carla, Monserrat, Claudia, Aiolli, Silvia, Luceri, Francesca, Lodovici, Maura, Menichetti, Stefano, Romanelli, Maria Novella

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Structure–activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists von Scapecchi, S., Marucci, G., Matucci, R., Angeli, P., Bellucci, C., Buccioni, M., Dei, S., Gualtieri, F., Manetti, D., Romanelli, M.N., Teodori, E.

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Exploratory Chemistry toward the Identification of a New Class of Multidrug Resistance Reverters Inspired by Pervilleine and Verapamil Models von Teodori, Elisabetta, Dei, Silvia, Garnier-Suillerot, Arlette, Gualtieri, Fulvio, Manetti, Dina, Martelli, Cecilia, Romanelli, Maria Novella, Scapecchi, Serena, Sudwan, Paiwan, Salerno, Milena

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Synthesis and binding properties of photoactivable biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein von TEODORI, E, ETTORI, D, GARNIER-SUILLEROT, A, GUALTIERI, F, MANETTI, D, ROMANELLI, M. N, SCAPECCHI, S

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Structure-affinity relationships of a unique nicotinic ligand: N(1)-dimethyl-N(4)-phenylpiperazinium iodide (DMPP) von Romanelli, M N, Manetti, D, Scapecchi, S, Borea, P A, Dei, S, Bartolini, A, Ghelardini, C, Gualtieri, F, Guandalini, L, Varani, K

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Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity von Dei, S, Bartolini, A, Bellucci, C, Ghelardini, C, Gualtieri, F, Manetti, D, Romanelli, M.N., Scapecchi, S, Teodori, E

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Design, Synthesis, and Preliminary Pharmacological Evaluation of 1,4-Diazabicyclo[4.3.0]nonan-9-ones as a New Class of Highly Potent Nootropic Agents von Manetti, Dina, Ghelardini, Carla, Bartolini, Alessandro, Bellucci, Cristina, Dei, Silvia, Galeotti, Nicoletta, Gualtieri, Fulvio, Romanelli, Maria Novella, Scapecchi, Serena, Teodori, Elisabetta

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Structural dependence of the allosteric interaction of semi-rigid verapamil analogues with dihydropyridine-binding in kitten heart von Voigt, Werner, Novella Romanelli, M., Lemoine, Horst, Mannhold, Raimund, Dei, Silvia, Teodori, Elisabetta, Gualtieri, Fulvio

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DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer von Ghelardini, C, Galeotti, N, Gualtieri, F, Romanelli, M N, Bucherelli, C, Baldi, E, Bartolini, A

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Structure−Activity Relationships Studies in a Series of N,N-Bis(alkanol)amine Aryl Esters as P-Glycoprotein (Pgp) Dependent Multidrug Resistance (MDR) Inhibitors von Martelli, Cecilia, Coronnello, Marcella, Dei, Silvia, Manetti, Dina, Orlandi, Francesca, Scapecchi, Serena, Novella Romanelli, Maria, Salerno, Milena, Mini, Enrico, Teodori, Elisabetta

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Amino Acids as Building Blocks for Carbonic Anhydrase Inhibitors von Chiaramonte, Niccolò, Romanelli, Maria Novella, Teodori, Elisabetta, Supuran, Claudiu T

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