Multiplexed immunohistochemistry, imaging, and quantitation: A review, with an assessment of Tyramide signal amplification, multispectral imaging and multiplex analysis von Stack, Edward C., Wang, Chichung, Roman, Kristin A., Hoyt, Clifford C.

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Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer von Lee, Sanghoon, Zhao, Li, Rojas, Christine, Bateman, Nicholas W., Yao, Hui, Lara, Olivia D., Celestino, Joseph, Morgan, Margaret B., Nguyen, Tri V., Conrads, Kelly A., Rangel, Kelly M., Dood, Robert L., Hajek, Richard A., Fawcett, Gloria L., Chu, Randy A., Wilson, Katlin, Loffredo, Jeremy L., Viollet, Coralie, Jazaeri, Amir A., Dalgard, Clifton L., Mao, Xizeng, Song, Xingzhi, Zhou, Ming, Hood, Brian L., Banskota, Nirad, Wilkerson, Matthew D., Te, Jerez, Soltis, Anthony R., Roman, Kristin, Dunn, Andrew, Cordover, David, Eterovic, Agda Karina, Liu, Jinsong, Burks, Jared K., Baggerly, Keith A., Fleming, Nicole D., Lu, Karen H., Westin, Shannon N., Coleman, Robert L., Mills, Gordon B., Casablanca, Yovanni, Zhang, Jianhua, Conrads, Thomas P., Maxwell, George L., Futreal, P. Andrew, Sood, Anil K.

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Multi-institutional TSA-amplified Multiplexed Immunofluorescence Reproducibility Evaluation (MITRE) Study von Taube, Janis M, Roman, Kristin, Engle, Elizabeth L, Wang, Chichung, Ballesteros-Merino, Carmen, Jensen, Shawn M, McGuire, John, Jiang, Mei, Coltharp, Carla, Remeniuk, Bethany, Wistuba, Ignacio, Locke, Darren, Parra, Edwin R, Fox, Bernard A, Rimm, David L, Hoyt, Cliff

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924 The spatial hierarchy of primary and recurrent medulloblastoma tumor ecosystems von Donovan, Laura, Hopkins, Bei, Draper, Ben, Shah, Rivani, Roman, Kristin, Remeniuk, Bethany

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51 A novel cross-site analysis of Vectra® Polaris™ multiplex fluorescence PD-1/PD-L1 immunohistochemistry on colorectal cancer with high and low microsatellite instability von Pollan, Sara, Remeniuk, Bethany, Hanifi, Arezoo, Roman, Kristin, Hopkins, Bei, Monteiro, Natalie, Nunns, Harry, Parnell, Erinn, William, Josette, Au, Qingyan

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A Review and Assessment of Potential Sources of Ethnic Differences in Drug Responsiveness von Bjornsson, Thorir D., Wagner, John A., Donahue, Stephen R., Harper, Dawn, Karim, Aziz, Khouri, Marlene S., Murphy, William R., Roman, Kristin, Schneck, Dennis, Sonnichsen, Daryl S., Stalker, Dennis J., Wise, Stephen D., Dombey, Stuart, Loew, Caroline

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Abstract 2831: Developing and validating a high-throughput 9-color immunofluorescence assay for translational studies in immuno-oncology research von Remeniuk, Bethany, Coltharp, Carla, Roman, Kristin, Wang, Chichung, Neumeister, Veronique, Hoyt, Clifford

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Abstract 153: Quantifying tumor heterogeneity and mapping complex immune cell interactions with high-throughput, 7-color multispectral slide scans von Coltharp, Carla, Johnson, Kent, Zhang, Wenliang, Wang, Chichung, Roman, Kristin, Eversole, Daniel, Hoyt, Clifford, Miller, Peter

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Evaluation of the Predictive Role of Tumor Immune Infiltrate in Patients with HER2-Positive Breast Cancer Treated with Neoadjuvant Anti-HER2 Therapy without Chemotherapy von De Angelis, Carmine, Nagi, Chandandeep, Hoyt, Cliff C., Liu, Linying, Roman, Kristin, Wang, Chichung, Zheng, Yi, Veeraraghavan, Jamunarani, Sethunath, Vidyalakshmi, Nuciforo, Paolo, Wang, Tao, Tsimelzon, Anna, Mao, Sufeng, Hilsenbeck, Susan G., Trivedi, Meghana V., Cataldo, Maria Letizia, Pavlick, Anne, Wolff, Antonio C., Weigelt, Britta, Reis-Filho, Jorge S., Prat, Aleix, Gutierrez, Carolina, Osborne, Charles Kent, Rimawi, Mothaffar F., Schiff, Rachel

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Automated Multiplex Immunofluorescence Panel for Immuno-oncology Studies on Formalin-fixed Carcinoma Tissue Specimens von Surace, Michael, DaCosta, Karma, Huntley, Anna, Zhao, Weiguang, Bagnall, Christopher, Brown, Charles, Wang, Chichung, Roman, Kristin, Cann, Jennifer, Lewis, Arthur, Steele, Keith, Rebelatto, Marlon, Parra, Edwin R, Hoyt, Clifford C, Rodriguez-Canales, Jaime

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Abstract LB-318: Multi-institutional TSA-amplified Multiplexed Immunofluorescence Reproducibility Evaluation (MITRE study): Reproducibility assessment of an automated multiplexed i... von Hoyt, Clifford, Roman, Kristin, Engle, Liz, Wang, Chichung, Ballesteros-Merino, Carmen, Jensen, Shawn M., McGuire, John, Zheng, Yi, Coltharp, Carla, Jiang, Mei, Lucas, Justin, Parra, Edwin, Wistuba, Ignacio, Locke, Darren, Fox, Bernard A., Rimm, David L., Taube, Janis Marie

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Abstract P5-04-07: Multispectral imaging allows visualization and quantification of multiple immunologic cell types in breast tumor tissues von Mittendorf, Elizabeth A, Wang, Chichung, Yau, Peng, Roman, Kristin, Wu, Yun, Alatrash, Gheath, Hoyt, Clifford

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Evaluation of the predictive role of tumor immune infiltrate in HER2-positive breast cancer patients treated with neoadjuvant anti-HER2 therapy without chemotherapy von De Angelis, Carmine, Nagi, Chandandeep, Hoyt, Cliff C., Liu, Linying, Roman, Kristin, Wang, Chichung, Zheng, Yi, Veeraraghavan, Jamunarani, Sethunath, Vidyalakshmi, Nuciforo, Paolo, Wang, Tao, Tsimelzon, Anna, Mao, Sufeng, Hilsenbeck, Susan G., Trivedi, Meghana V., Cataldo, Maria Letizia, Pavlick, Anne C., Wolff, Antonio C., Weigelt, Britta, Reis-Filho, Jorge S., Prat, Aleix, Gutierrez, Carolina, Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel

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Abstract 5123: Multiplex in situ immunoprofiling and survival outcomes in non-small cell lung cancer von Lin, Steven H., Mansfield, James R., Rao, Xiayu, Jiang, Wen, Fang, Penny, Roman, Kristin, Wang, Chichung, Komaki, Ritsuko, Hahn, Stephen, Swisher, Stephen G., Fujimoto, Junya, Wistuba, Ignacio, Wang, Jing, Hoyt, Clifford C.

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Evaluation of tumor immune infiltrate as a determinant of response to neo-adjuvant lapatinib and trastuzumab (LT) in HER2-positive (+) breast cancer (BC) von De Angelis, Carmine, Nagi, Chandandeep, Hoyt, Cliff, Linying, Liu, Roman, Kristin, Wang, Chichung, Zheng, Yi, Wang, Tao, Mao, Rena, Hilsenbeck, Susan G., Gutierrez, Carolina, Wolff, Antonio C., Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel

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Automated Multiplex Immunofluorescence Panel for Immuno-oncology Studies on Formalin-fixed Carcinoma Tissue Specimens von Surace, Michael, DaCosta, Karma, Huntley, Anna, Zhao, Weiguang, Bagnall, Christopher, Brown, Charles, Wang, Chichung, Roman, Kristin, Cann, Jennifer, Lewis, Arthur, Steele, Keith, Rebelatto, Marlon, Parra, Edwin R., Hoyt, Clifford C., Rodriguez-Canales, Jaime

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Evaluation of Concordance Between Original Death Certifications and an Expert Panel Process in the Determination of Sudden Unexplained Death in Childhood von Crandall, Laura Gould, Lee, Joyce H., Friedman, Daniel, Lear, Kelly, Maloney, Katherine, Pinckard, J. Keith, Lin, Peter, Andrew, Thomas, Roman, Kristin, Landi, Kristen, Jarrell, Heather, Williamson, Alex K., Downs, J. C. Upshaw, Pinneri, Kathy, William, Christopher, Maleszewski, Joseph J., Reichard, R. Ross, Devinsky, Orrin

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Characterizing immune evasion in FFPE tissue sections - a new method for measuring cellular interactions via multiplexed phenotype mapping and spatial point patterns von Hoyt, Clifford, Wang, Chichung, Roman, Kristin, Johnson, Kent, Miller, Peter, Mittendorf, Elizabeth

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31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one: National Harbor, MD, USA. 9-13 November 2016 von Ramakrishnan, Rupal, Murthy, Ravi, Wargo, Jennifer, Luke, Jason J, Suryawanshi, Satyendra, Menk, Ashley V, Mostafid, Hugh, Harrington, Kevin, Grose, Mark, Van den Eynde, Marc, Ramachandran, Indu, Jensen, Shawn, Ott, Sascha, Lyngaa, Rikke, Fan, Aaron, Assadipour, Yasmine, Chinnasamy, Harshini, Rabinovich, Brian, Zoon, Kathryn C, Frey, Alan, Abdul-Alim, Siddiq, Mattsson, Jonas, Villarroel, Patricio Pérez, Schult, Silke, Kodumudi, Krithika, Havunen, Riikka, Lee, Tien, Grossenbacher, Steven K, Jennewein, Lukas, Joshi, Nikhil, Eyquem, Justin, Sadelain, Michel, Kim, Sung, Ogden, Julia, Hodgson, Darren R, Pan, Fan, Dennis, Lucas, Bryant, Bonita, Duhen, Thomas, Montler, Ryan, Kaufman, David R, Kang, S. Peter, Yearley, Jennifer, Guyre, Cheryl A, Trehu, Elizabeth, Hodkinson, Brendan P, Silski, Cynthia, O’Connor, Alison, Lai, Shu-Chuan, Scheel, Birgit, Wiegand, Volker, Katsarlinos, P, Kaufman, Howard L, Monette, Anne, Slingluff, Craig L, Vuyyuru, Raja, Graziano, Robert F, Clark, Joseph I, Asmellash, Senait, Petruzelka, Lubos, Ting, David, Tsai, Katy, Rosenblum, Michael, Ashworth-Sharpe, Julia, Farrell, Michael, Zhu, Yifei, Tsujikawa, Takahiro, Thibault, Guillaume, Ignacio, Eduardo, Merritt, Chris, Bernett, Matthew J, Zimarino, Carlo, Dubey, Aparajita, Veninga, Henrike, Shamsili, Setareh, Yee, Andrew J, Motzer, Robert J, Ross, Ashley, Paria, Biman, Lam, Bao, Dragnev, Konstanin, Hamadani, Mehdi, Sabado, Rachel, William, Loging, Zanhow, Cynthia, Weissman, Irving L, Gan, Hui, Colyer, Duncan, Millward, Michael, Kher, Uma, de Oliveira, Moacyr Ribeiro, Yu, Evan Y, Cordes, Lisa, Cao, Alexander, Weidlick, Jeffrey, Rothe, Christine, Hua, Ping, Freeman, Gordon J, Henningsohn, Lars, Huang, Hongying

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31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one von Zhang, Xiaonan, Lorent, Julie, Uemura, Marc, Tawbi, Hussein, Woodman, Scott, Bernatchez, Chantale, Logan, Theodore, Gu, Xuemin, Khushalani, Nikhil, Toth, Kyle, Carpentier, Sabrina, Galon, Jérôme, Haydu, Lauren E, Kline, Douglas, Workman, Creg, Ansa-Addo, Ephraim A, Maroto, Miguel, Chagin, Karen, Mackall, Crystal, Bennett, Alan D, Felber, Barbara, Assadipour, Yasmine, Gokuldass, Aishwarya, Hammill, Joanne, Bramson, Jonathan, Yu, Zhiya, Soon-Shiong, Patrick, Ruella, Marco, Hegde, Meenakshi, Hovgaard, Dorrit, Nguyen, Sang, Xue, Allen, Veerapathran, Anandaraman, Gunset, Gertrude, Angell, Helen K, Hodgson, Darren R, Ayers, Mark, Levitan, Diane, Liu, Fang, Yung-Jue Bang, Schalper, Kurt, Topalian, Suzanne, Conlon, Kevin, Delcommenne, Marc, Chin-Fu, Hsiao, Backert, Linus, Howells-Ferreira, Ana, Siraj, Ali, White, Eileen, Sun, Yongming, Glenn, Sean, Ehrmann, Jon M, Korman, Alan J, Reuben, Alex, Amin, Asim, Steingrimsson, Arni, Tufman, Amanda, Berger, Frank, Handy, John, Tian, Zhigang, Kulkarni, Anupriya, Edward El Rassi, Clayburgh, Daniel R, Hagberg, Hans, Zimarino, Carlo, De Bono, Johann, Özcan Met, Grossenbacher, Steven, Richards, Jon, Le, Dung T, Lee, Jean K, Leighl, Natasha, Copeland, Larry, Nam, Kijoeng, Pegram, Mark D, Juhler-Nøttrup, Trine, Tran, Ben, Qin, Zhen, Khattri, Arun, Shah, Jatin, Matsumoto, Morio, Yimer, Habte, MacKinnon, Andy, Whiting, Sam, Sondel, Paul M, Heery, Christopher R, Esteller, Manel, Park, Johanna, Leland, Pamela, Hastings, William D, Dranoff, Glenn, Bose, Nandita, Crocker, Andrea, Hartnett, Jim, Cong, Mei, Rachida-Siham Bel Aiba, Spranger, Stefani, Shukla, Sachet A, Boussiotis, Vassiliki A, Moran, Amy E

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